-
1
-
-
85047684589
-
Using chemical categories to fill data gaps in hazard assessment
-
van Leeuwen K, Schultz TW, Henry T et al. (2009) Using chemical categories to fill data gaps in hazard assessment. SAR QSAR Environ Res 20:207–220
-
(2009)
SAR QSAR Environ Res
, vol.20
, pp. 207-220
-
-
van Leeuwen, K.1
Schultz, T.W.2
Henry, T.3
-
3
-
-
77955860930
-
Grouping of petroleum substances
-
Worth AP, Patlewicz G, Available from ECB website
-
Comber M, Simpson B (2007) Grouping of petroleum substances. In: Worth AP, Patlewicz G (eds) A compendium of case studies that helped to shape the REACH guidance on chemical categories and read across. EUR report no 22481 EN. European Chemicals Bureau, Joint Research Centre, European Commission, Ispra, Italy. Available from ECB website: http://ecb.jrc.it/qsar/background/index.php?c=CAT
-
(2007)
A Compendium of Case Studies that Helped to Shape the REACH Guidance on Chemical Categories and Read Across. EUR Report No 22481 EN. European Chemicals Bureau, Joint Research Centre, European Commission, Ispra, Italy
-
-
Comber, M.1
Simpson, B.2
-
5
-
-
8344223858
-
The prospects for using (Q)SARs in a changing political environment—high expectations and a key role for the European Commission’s Joint Research Centre
-
Worth AP, van Leeuwen CJ, Hartung T (2004) The prospects for using (Q)SARs in a changing political environment—high expectations and a key role for the European Commission’s Joint Research Centre. SAR QSAR Environ Res 15:331–343
-
(2004)
SAR QSAR Environ Res
, vol.15
, pp. 331-343
-
-
Worth, A.P.1
van Leeuwen, C.J.2
Hartung, T.3
-
6
-
-
33748640373
-
Mechanistic applicability domains for non-animal based prediction of toxicological end points: General principles and application to reactive toxicity
-
Aptula AO, Roberts DW (2006) Mechanistic applicability domains for non-animal based prediction of toxicological end points: general principles and application to reactive toxicity. Chem Res Toxicol 19:1097–1105
-
(2006)
Chem Res Toxicol
, vol.19
, pp. 1097-1105
-
-
Aptula, A.O.1
Roberts, D.W.2
-
7
-
-
33749004016
-
Mechanistic applicability domains for non-animal based prediction of toxicological endpoints. QSAR analysis of the Schiff base applicability domain for skin sensitization
-
Roberts DW, Aptula AO, Patlewicz G (2006) Mechanistic applicability domains for non-animal based prediction of toxicological endpoints. QSAR analysis of the Schiff base applicability domain for skin sensitization. Chem Res Toxicol 19:1228–1233
-
(2006)
Chem Res Toxicol
, vol.19
, pp. 1228-1233
-
-
Roberts, D.W.1
Aptula, A.O.2
Patlewicz, G.3
-
8
-
-
0000898029
-
Identification of mechanisms of toxic action of phenols to Tetrahymena pyriformis from molecular descriptors
-
Chen F, Schuurmann G, SETAC, Florida
-
Schultz TW, Sinks GD, Cronin MTD (1997) Identification of mechanisms of toxic action of phenols to Tetrahymena pyriformis from molecular descriptors. In: Chen F, Schuurmann G (eds) Quantitative Structure-Activity Relationships in Environmental Sciences VII, SETAC, Florida
-
(1997)
Quantitative Structure-Activity Relationships in Environmental Sciences VII
-
-
Schultz, T.W.1
Sinks, G.D.2
Cronin, M.T.D.3
-
9
-
-
47349112107
-
Toxmatch – a new software tool to aid in the development and evaluation of chemically similar groups
-
Patlewicz G, Jeliazkova N, Gallegos Saliner A et al. (2008) Toxmatch – a new software tool to aid in the development and evaluation of chemically similar groups. SAR QSAR Environ Res 19:397–412
-
(2008)
SAR QSAR Environ Res
, vol.19
, pp. 397-412
-
-
Patlewicz, G.1
Jeliazkova, N.2
Gallegos Saliner, A.3
-
10
-
-
67949118899
-
Formation of structural categories to allow for read-across for reproductive toxicity
-
Enoch SJ, Cronin MTD, Madden JC et al. (2009) Formation of structural categories to allow for read-across for reproductive toxicity. QSAR Comb Sci 28:696–708
-
(2009)
QSAR Comb Sci
, vol.28
, pp. 696-708
-
-
Enoch, S.J.1
Cronin, M.T.D.2
Madden, J.C.3
-
11
-
-
85073170962
-
-
US EPA (2002) Chemical categories report (http://www.epa.gov/opptintr/newchems/pubs/chemcat.htm)
-
(2002)
Chemical Categories Report
-
-
-
13
-
-
85073150848
-
-
UNEP Chemicals Screening Information Dataset (SIDS) for High Volume Chemicals
-
UNEP Chemicals Screening Information Dataset (SIDS) for High Volume Chemicals (http://www.chem.unep.ch/irptc/sids/OECDSIDS/sidspub.html)
-
-
-
-
14
-
-
33749857464
-
A category approach for reproductive effects of phthalates
-
Fabjan E, Hulzebos E, Mennes W et al. (2006) A category approach for reproductive effects of phthalates. Crit Rev Toxicol 36:695–726
-
(2006)
Crit Rev Toxicol
, vol.36
, pp. 695-726
-
-
Fabjan, E.1
Hulzebos, E.2
Mennes, W.3
-
15
-
-
25444520273
-
Skin sensitization: Reaction mechanistic applicability domains for structure-activity relationships
-
Aptula AO, Patlewicz G, Roberts DW (2005) Skin sensitization: reaction mechanistic applicability domains for structure-activity relationships. Chem Res Toxicol 18:1420–1426
-
(2005)
Chem Res Toxicol
, vol.18
, pp. 1420-1426
-
-
Aptula, A.O.1
Patlewicz, G.2
Roberts, D.W.3
-
16
-
-
57349172613
-
Reactivity assays for non-animal based prediction of skin sensitisation potential
-
Aptula AO, Roberts DW, Schultz TW et al. (2007) Reactivity assays for non-animal based prediction of skin sensitisation potential. Toxicol 231:117–118
-
(2007)
Toxicol
, vol.231
, pp. 117-118
-
-
Aptula, A.O.1
Roberts, D.W.2
Schultz, T.W.3
-
17
-
-
0030981036
-
Predicting modes of toxic action from chemical structure: Acute toxicity in the fathead minnow (Pimephales promelas)
-
Russom CL, Bradbury SP, Broderius SJ (1997) Predicting modes of toxic action from chemical structure: acute toxicity in the fathead minnow (Pimephales promelas). Environ Toxicol Chem 16:948–967
-
(1997)
Environ Toxicol Chem
, vol.16
, pp. 948-967
-
-
Russom, C.L.1
Bradbury, S.P.2
Broderius, S.J.3
-
18
-
-
0036123607
-
Regression comparisons of Tetrahymena pyriformis and Poecilia reticulata toxicity
-
Seward JR, Hamblen EL, Schultz TW (2002) Regression comparisons of Tetrahymena pyriformis and Poecilia reticulata toxicity. Chemosphere 47:93–101
-
(2002)
Chemosphere
, vol.47
, pp. 93-101
-
-
Seward, J.R.1
Hamblen, E.L.2
Schultz, T.W.3
-
19
-
-
35148890884
-
Verification of the structural alerts for Michael acceptors
-
Schultz TW, Yarbrough JW, Hunter RS et al. (2007) Verification of the structural alerts for Michael acceptors. Chem Res Toxicol 20:1359–1363
-
(2007)
Chem Res Toxicol
, vol.20
, pp. 1359-1363
-
-
Schultz, T.W.1
Yarbrough, J.W.2
Hunter, R.S.3
-
20
-
-
53849113018
-
Identification of mechanisms of toxic action for skin sensitisation using a SMARTS pattern based approach
-
Enoch SJ, Madden JC, Cronin MTD (2008) Identification of mechanisms of toxic action for skin sensitisation using a SMARTS pattern based approach. SAR QSAR Environ Res 19:555–578
-
(2008)
SAR QSAR Environ Res
, vol.19
, pp. 555-578
-
-
Enoch, S.J.1
Madden, J.C.2
Cronin, M.T.D.3
-
21
-
-
41649114183
-
Quantitative and mechanistic read across for predicting the skin sensitization potential of alkenes acting via Michael addition
-
Enoch SJ, Cronin MTD, Schultz TW et al. (2008) Quantitative and mechanistic read across for predicting the skin sensitization potential of alkenes acting via Michael addition. Chem Res Toxicol 21:513–520
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 513-520
-
-
Enoch, S.J.1
Cronin, M.T.D.2
Schultz, T.W.3
-
22
-
-
33846889946
-
Electrophilic chemistry related to skin sensitization. Reaction mechanistic applicability domain classification for a published data set of 106 chemicals tested in the mouse local lymph node assay
-
Roberts DW, Aptula AO, Patlewicz G (2007) Electrophilic chemistry related to skin sensitization. Reaction mechanistic applicability domain classification for a published data set of 106 chemicals tested in the mouse local lymph node assay. Chem Res Toxicol 20:44–60
-
(2007)
Chem Res Toxicol
, vol.20
, pp. 44-60
-
-
Roberts, D.W.1
Aptula, A.O.2
Patlewicz, G.3
-
23
-
-
2442687730
-
Further evaluation of quantitative structure-activity relationship models for the prediction of the skin sensitization potency of selected fragrance allergens
-
Patlewicz GY, Basketter DA, Pease CKS et al. (2004) Further evaluation of quantitative structure-activity relationship models for the prediction of the skin sensitization potency of selected fragrance allergens. Contact Derm 50:91–97
-
(2004)
Contact Derm
, vol.50
, pp. 91-97
-
-
Patlewicz, G.Y.1
Basketter, D.A.2
Pease, C.K.S.3
-
24
-
-
0036823303
-
Structure-activity relationships for selected fragrance allergens
-
Patlewicz GY, Wright ZM, Basketter DA et al. (2002) Structure-activity relationships for selected fragrance allergens. Contact Derm 47:219–226
-
(2002)
Contact Derm
, vol.47
, pp. 219-226
-
-
Patlewicz, G.Y.1
Wright, Z.M.2
Basketter, D.A.3
-
25
-
-
58149085640
-
Formation of categories from structure-activity relationships to allow read-across for risk assessment: Toxicity of α, β-unsaturated carbonyl compounds
-
Koleva YK, Madden JC, Cronin MTD (2008) Formation of categories from structure-activity relationships to allow read-across for risk assessment: toxicity of α, β-unsaturated carbonyl compounds. Chem Res Toxicol 21:2300–2312
-
(2008)
Chem Res Toxicol
, vol.21
, pp. 2300-2312
-
-
Koleva, Y.K.1
Madden, J.C.2
Cronin, M.T.D.3
-
28
-
-
30144443263
-
Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods
-
Gerberick GF, Ryan CA, Kern PS et al. (2005) Compilation of historical local lymph node data for evaluation of skin sensitization alternative methods. Dermatitis 16:157–202
-
(2005)
Dermatitis
, vol.16
, pp. 157-202
-
-
Gerberick, G.F.1
Ryan, C.A.2
Kern, P.S.3
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