Interaction of differently functionalized fluorescent silica nanoparticles with neural stem- and tissue-type cells

Nanotoxicology

Volumn 8, Issue SUPPL. 1, 2014, Pages 138-148

  Izak Nau, Emilia ^a,b   Kenesei, Kata ^c   Murali, Kumarasamy ^c   Voetz, Matthias ^a   Eiden, Stefanie ^a   Puntes, Victor F ^d   Duschl, Albert ^b   Madarász, Emilia ^c  

^a BAYER AG   (Germany)

^b UNIVERSITY OF SALZBURG   (Austria)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^d CATALAN INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY ICN2   (Spain)

Author keywords

Fluorescence spectrum analysis; Neural cell types; Silica NP; Toxicity; Uptake

Indexed keywords

FLUORESCENT DYE; LACTATE DEHYDROGENASE; NANOPARTICLE; POVIDONE; SILICON DIOXIDE; SILICON DIOXIDE NANOPARTICLE; UNCLASSIFIED DRUG;

ABSORPTION; ADSORPTION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BIOLOGICAL ACTIVITY; CELL INTERACTION; CELL METABOLISM; CELL SURFACE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY ASSAY; DISPERSION; INTERNALIZATION; MICROGLIA; MOUSE; NANOFABRICATION; NERVE CELL NECROSIS; NERVOUS TISSUE; NEURAL STEM CELL; NEUROTOXICITY; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TOXICITY TESTING; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; CELL LINE; CHEMISTRY; CYTOLOGY; ELECTRON MICROSCOPY; HUMAN;

CELL LINE; FLUORESCENT DYES; HUMANS; MICROSCOPY, ELECTRON; NANOPARTICLES; NEURAL STEM CELLS; SILICON DIOXIDE;

EID: 84887817489     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2013.864427     Document Type: Article

References (55)

1. Aillon KL, Xie YM, El-Gendy N, Berkland CJ, Forrest ML. 2009. Effects of nano-material physicochemical properties on in vivo toxicity. Adv Drug Deliv Rev 61: 457-66.
2. Ariano P, Zamburlin P, Gilardino A, Mortera R, Onida B, Tomatis M, et al. 2011. Interaction of spherical silica nanoparticles with neuronal cells: size-dependent toxicity and perturbation of calcium homeostasis. Small 7: 766-74.
3. Brunauer S, Emmett PH, Teller E. 1938. Adsorption of gases in multimolecular layers. J Am Chem Soc 60: 309-19.
4. Bühler V. 2005. Excipients for Pharmaceuticals - Povidone, Crospovidone and Copovidone. Heidelberg, Germany: Springer.
5. Cao G. 2004. Nanostructures and Nanomaterials: Synthesis, Properties and Applications. London, UK: Imperial College Press.
6. Dickinson ME, Bearman G, Tille S, Lansford R, Fraser SE. 2001. Multi-spectral imaging and linear unmixing add a whole new dimension to laser scanning fluorescence microscopy. BioTechniques 31: 1272-8.
7. Ehrenberg MS, Friedman AE, Finkelstein JN, Oberdörster G, McGrath JL. 2009. The influence of protein adsorption on nanoparticle association with cultured endothelial cells. Biomaterials 30: 603-10.
8. Gangwal S, Brown JS, Wang A, Houck KA, Dix DJ, Kavlock RJ, Hubal EAC. 2011. Informing selection of nanomaterial concentrations for ToxcCast in vitro testing based on occupational exposure potential. Environ Health Perspect 119: 1539-46.
9. Goodman CM, McCusker CD, Yilmaz T, Rotello VM. 2004. Toxicity of gold nanoparticles functionalized with cationic and anionic sidechains. Bioconjug Chem 15: 897-900.
10. Hádinger N, Varga B, Berzsenyi S, Környei Zs, Madarász E, Herberth B. 2009. Retinoic acid regulates astrogliogenesis. Int J Dev Neurosci 27: 365-75.
11. Haraguchi T, Shimi T, Koujin T, Hashiguchi N, Hiraoka Y. 2002. Spectral imaging fluorescence microscopy. Gene Cell 7: 881-7.
12. Heider EC, Barhoum M, Peterson EM, Schaefer J, Harris JM. 2010. Identification of single fluorescent labels using spectroscopic microscopy. Appl Spectrosc 64: 37-45.
13. Hettich C, Kalkbrenner T, Gerhardt I, Kühn S, Sandoghdar V. 2003. Single molecules, single nanoparticles and their optical interaction. 12th International Conference on Scanning Tunneling Microscopy/Spectroscopy and Related Techniques, 2003, July 21-25, Eindhoven, the Netherlands, 696: 127-35.
14. Hirsch LR, Stafford RJ, Bankson JA, Sershen SR, Rivera B, Price RE, et al. 2003. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc Natl Acad Sci USA 100: 13549-54.
15. Horie M, Nishio K, Fujita K, Endoh S, Miyauchi A, Saito Y, et al. 2009. Protein adsorption of ultrafine metal oxide and its influence on cytotoxicity toward cultured cells. Chem Res Toxicol 22: 543-53.
16. Jin Y, Kannan S, Wu M, Zhao JX. 2007. Toxicity of luminescent silica nanoparticles to living cells. Chem Res Toxicol 20: 1126-33.
17. Kazuho A, Norio M. 2000. Measurement of cellular 3-(4, 5-dimethylthiazol- 2-yl)-2, 5-diphenyltetrazolium bromide (MTT) reduction activity and lactate dehydrogenase release using MTT. Neurosci Res 38: 325-9.
18. Kim JS, Yoon TJ, Yu KN, Kim BG, Park SJ, Kim HW, et al. 2006. Toxicity and tissue distribution of magnetic nanoparticles in mice. Toxicol Sci 89: 338-47.
19. Kirchner C, Liedl T, Kudera S, Pellegrino T, Javier AM, Gaub HE, et al. 2005. Cytotoxicity of colloidal CdSe and CdSe/ZnS nanoparticles. Nano Lett 5: 331-8.
20. Lanone S, Boczkowski J. 2006. Biomedical applications and potential health risks of nanomaterials: molecular mechanisms. Curr Mol Med 6: 651-63.
21. Limbach LK, Grass RN, Stark WJ. 2009. Physico-chemical differences between particle- and molecule-derived toxicity: can we make inherently safe nanoparticles? CHIMIA Int J Chem 63: 38-43.
22. Limbach LK, Wick P, Manser P, Grass RN, Bruinink A, Stark WJ. 2007. Exposure of engineered nanoparticles to human lung epithelial cells: influence of chemical composition and catalytic activity on oxidative stress. Environ Sci Technol 41: 4158-63.
23. Lockman PR, Koziara JM, Mumper RJ, Allen DD. 2004. Nanoparticle surface charges alter blood-brain barrier integrity and permeability. J Drug Target 12: 635-41.
24. Madarász E, Kiss J, Bartók I. 1984. Cell production and morphological pattern formation in primary brain cell cultures. Brain Res 304: 339-49.
25. Madarász E, Theodosis DT, Poulain DA. 1991. In vitro formation of type 2 astrocytes derived from postnatal rat hypothalamus or cerebral cortex. Neuroscience 43: 211-21.
26. Monopoli MP, Walczyk D, Campbell A, Elia G, Lynch I, Baldelli- Bombelli F, Dawson KA. 2011. Physico-chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles. JACS 133: 2525-34.
27. Mosmann T. 1983. Rapid colorimetric assay for cellular growth and survival: application and proliferation and cytotoxicity assays. J Immunol Methods 65: 55-63.
28. Nabeshi H, Yoshikawa T, Matsuyama K, Nakazato Y, Arimori A, Isobe M, et al. 2010. Size-dependent cytotoxic effects of amorphous silica nanoparticles on Langerhans cells. Pharmazie 65: 199-201.
29. Naqvi S, Samim M, Abdin M, Ahmed FJ, Maitra A, Prashant C, Dinda AK. 2010. Concentration-dependent toxicity of iron oxide nanoparticles mediated by increased oxidative stress. Int J Nanomedicine 5: 983-9.
30. Oberdörster G. 2010. Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology. J Intern Med 267: 89-105.
31. Oberdörster G, Maynard A, Donaldson K, Castranova V, Fitzpatrick J, Ausman K, et al. 2005. Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Part Fibre Toxicol 2: 1-35.
32. Ow H, Larson DR, Srivastava M, Baird BA, Webb WW, Wiesner U. 2005. Bright and stable core-shell fluorescent silica nanoparticles. Nano Lett 5: 113-17.
33. Petersen EJ, Nelson BC. 2010. Mechanisms and measurements of nanomaterial-induced oxidative damage to DNA. Anal Bioanal Chem 398: 613-50.
34. Pickard MR, Chari DM. 2010. Robust uptake of magnetic nanoparticles (MNPS) by central nervous system (CNS) microglia: implications for particle uptake in mixed neural cell populations. Int J Mol Sci 11: 967-81.
35. Powers KW, Palazuelos M, Moudgil BM, Roberts SM. 2007. Characterization of the size, shape, and state of dispersion of nanoparticles for toxicological studies. Nanotoxicology 1: 42-51.
36. Ravi Kumar MNV, Sameti M, Mohapatra SS, Kong X, Lockey RF, Bakowsky U, et al. 2004. Cationic silica nanoparticles as gene carriers: synthesis, characterization and transfection efficiency in vitro and in vivo. J Nanosci Nanotechnol 4: 876-81.
37. Rejman J, Oberle V, Zuhorn IS, Hoekstra D. 2004. Size-dependent internalization of particles via the pathways of clathrin- and caveolae -mediated endocytosis. Biochem J 377: 159-69.
38. Resch-Genger U, Grabolle M, Nitschke R, Nann T. 2010. Nanocrystals and nanoparticles versus molecular fluorescent labels as reporters for bioanalysis and the life sciences: a critical comparison. In: Demchenko AP, ed. Advanced Fluorescence Reporters in Chemistry and Biology II. Springer Series on Fluorescence Methods and Applications. Berlin, Heidelberg: Springer-Verlag, 3-40.
39. Robinson S, Williams PA. 2002. Inhibition of protein adsorption onto silica by polyvinylpyrrolidone. Langmuir 18: 8743-8.
40. Ruedas-Rama MJ, Walters JD, Orte A, Hall EAH. 2012. Fluorescent nanoparticles for intracellular sensing: a review. Anal Chim Acta 751: 1-23.
41. Salvati A, A berg C, dos Santos T, Varela J, Pinto P, Lynch I, Dawson KA. 2011. Experimental and theoretical comparison of intracellular import of polymeric nanoparticles and small molecules: toward models of uptake kinetics. Nanomedicine 7: 818-26.
42. Saura J, Tusell JM, Serratosa J. 2003. High-yield isolation of murine microglia by mild trypsinization. Glia 44: 183-9.
43. Schlett K, Madarász E. 1997. Retinoic acid induced neural differentiation in a neuroectodermal cell line immortalized by p53 deficiency. J Neurosci Res 47: 405-15.
44. Slowing II, Vivero-Escoto JL, Wu CW, Lin VS. 2008. Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers. Adv Drug Deliv Rev 60: 1278-88.
45. Stark WJ. 2011. Nanoparticles in biological systems. Angew Chem Int Ed Engl 50: 1242-58.
46. Stöber W, Fink A, Bohn EJ. 1868. Controlled growth of monodisperse silica spheres in the micron size range. J Colloid Interface Sci 26: 62-9.
47. Sun L, Li Y, Liu X, Jin M, Zhang L, Du Z, et al. 2011. Cytotoxicity and mitochondrial damage caused by silica nanoparticles. Toxicol In Vitro 25: 1619-29.
48. Sundaram S, Roy SK, Ambati BK, Kompella UB. 2009. Surface functionalized nanoparticles for targeted gene delivery across nasal respiratory epithelium. FASEB J 23: 3752-65.
49. Varga B, Hádinger N, Gócza E, Dulberg V, Demeter K, Madarász E, Herberth B. 2008. Generation of diverse neuronal subtypes in cloned populations of stem-like cells. BMC Devl Biol 8: 89-107.
50. Verma A, Stellacci F. 2010. Effect of surface properties on nanoparticlecell interactions. Small 6: 12-21.
51. Vijayanathan V, Thomas T, Thomas TJ. 2002. DNA nanoparticles and development of DNA delivery vehicles for gene therapy. Biochemistry 41: 14085-94.
52. Walcarius A, Ganesan V. 2006. Ion-exchange properties and electrochemical characterization of quaternary ammonium-functionalized silica microspheres obtained by the surfactant template route. Langmuir 22: 469-77.
53. Xia T, Kovochich M, Liong M, Zink JI, Nel AE. 2008. Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways. ACS Nano 2: 85-96.
54. Yang H, Wu Q, Tang M, Kong L, Lu Z. 2009. Cell membrane injury induced by silica nanoparticles in mouse macrophage. J Biomed Nanotechnol 5: 528-35.
55. Zhu Y, Li W, Li Q, Li Y, Li Y, Zhang X, Huang Q. 2009. Effects of serum proteins on intracellular uptake and cytotoxicity of carbon nanoparticles. Carbon 47: 1351-8.