-
1
-
-
0032742992
-
The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
-
Weyer C, Bogardus C, Mott DM, Pratley RE. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 1999; 104: 787-794.
-
(1999)
J Clin Invest
, vol.104
, pp. 787-794
-
-
Weyer, C.1
Bogardus, C.2
Mott, D.M.3
Pratley, R.E.4
-
2
-
-
0842284799
-
β-Cell glucotoxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes
-
Robertson RP, Harmon J, Tran PO, Poitout V. β-Cell glucotoxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes. Diabetes 2004; 53(Suppl. 1): S119-S124.
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 1
-
-
Robertson, R.P.1
Harmon, J.2
Tran, P.O.3
Poitout, V.4
-
3
-
-
33745863033
-
Islet β-cell failure in type 2 diabetes
-
Prentki M, Nolan CJ. Islet β-cell failure in type 2 diabetes. J Clin Invest 2006; 116: 1802-1812.
-
(2006)
J Clin Invest
, vol.116
, pp. 1802-1812
-
-
Prentki, M.1
Nolan, C.J.2
-
4
-
-
7444234167
-
Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of β-cell function
-
Li YB, Xu W, Liao ZH, et al. Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of β-cell function. Diabetes Care 2004; 27: 2597-2602.
-
(2004)
Diabetes Care
, vol.27
, pp. 2597-2602
-
-
Li, Y.B.1
Xu, W.2
Liao, Z.H.3
-
5
-
-
43849105857
-
Effect of intensive insulin therapy on β-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomized parallel-group trial
-
Weng JP, Li YB, Xu W, et al. Effect of intensive insulin therapy on β-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomized parallel-group trial. Lancet 2008; 371: 1753-1760.
-
(2008)
Lancet
, vol.371
, pp. 1753-1760
-
-
Weng, J.P.1
Li, Y.B.2
Xu, W.3
-
6
-
-
79959484802
-
The ADOPT study group. Effects of rosiglitazone, glyburide, and metformin on b-cell function and insulin sensitivity in ADOPT
-
Kahn SE, Lachin JM, Zinman B, et al. The ADOPT study group. Effects of rosiglitazone, glyburide, and metformin on b-cell function and insulin sensitivity in ADOPT. Diabetes 2011; 60: 1552-1560.
-
(2011)
Diabetes
, vol.60
, pp. 1552-1560
-
-
Kahn, S.E.1
Lachin, J.M.2
Zinman, B.3
-
7
-
-
84866268783
-
American Diabetes Association (ADA); European Association for the Study of Diabetes (EASD). Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
-
Inzucchi SE, Bergenstal RM, Buse JB, et al. American Diabetes Association (ADA); European Association for the Study of Diabetes (EASD). Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2012; 35: 1364-1379.
-
(2012)
Diabetes Care
, vol.35
, pp. 1364-1379
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
-
8
-
-
33751159555
-
Long-term efficacy of metformin therapy in nonobese individuals with type 2 diabetes
-
Ong CR, Molyneaux LM, Constantino MI, Twigg SM, Yue DK. Long-term efficacy of metformin therapy in nonobese individuals with type 2 diabetes. Diabetes Care 2006; 29: 2361-2364.
-
(2006)
Diabetes Care
, vol.29
, pp. 2361-2364
-
-
Ong, C.R.1
Molyneaux, L.M.2
Constantino, M.I.3
Twigg, S.M.4
Yue, D.K.5
-
9
-
-
80051978747
-
Use of metformin in the setting of mild-to-moderate renal insufficiency
-
Lipska KJ, Bailey CJ, Inzucchi SE. Use of metformin in the setting of mild-to-moderate renal insufficiency. Diabetes Care 2011; 34: 1431-1437.
-
(2011)
Diabetes Care
, vol.34
, pp. 1431-1437
-
-
Lipska, K.J.1
Bailey, C.J.2
Inzucchi, S.E.3
-
11
-
-
84874545012
-
Impact of baseline BMI on glycemic control and weight change with metformin monotherapy in Chinese type 2 diabetes patients: phase IV open-label trial
-
Ji L, Li H, Guo X, Li Y, Hu R, Zhu Z. Impact of baseline BMI on glycemic control and weight change with metformin monotherapy in Chinese type 2 diabetes patients: phase IV open-label trial. PLoS One 2013; 8: e57222.
-
(2013)
PLoS One
, vol.8
-
-
Ji, L.1
Li, H.2
Guo, X.3
Li, Y.4
Hu, R.5
Zhu, Z.6
-
12
-
-
0028963260
-
United Kingdom Prospective Diabetes Study (UKPDS 13): relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed three years
-
United Kingdom Prospective Diabetes Study Group.
-
United Kingdom Prospective Diabetes Study Group. United Kingdom Prospective Diabetes Study (UKPDS 13): relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed three years. BMJ 1995; 310: 83-88.
-
(1995)
BMJ
, vol.310
, pp. 83-88
-
-
-
13
-
-
33646941576
-
Long-term efficacy of sulfonylureas: a United Kingdom Prospective Diabetes Study perspective
-
Holman RR. Long-term efficacy of sulfonylureas: a United Kingdom Prospective Diabetes Study perspective. Metabolism 2006; 55: S2-S5.
-
(2006)
Metabolism
, vol.55
-
-
Holman, R.R.1
-
14
-
-
0025837055
-
Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects
-
DeFronzo RA, Barzilai N, Simonson DC. Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects. J Clin Endocrinol Metab 1991; 73: 1294-1301.
-
(1991)
J Clin Endocrinol Metab
, vol.73
, pp. 1294-1301
-
-
DeFronzo, R.A.1
Barzilai, N.2
Simonson, D.C.3
-
15
-
-
0036318319
-
Lipotoxicity in human pancreatic islets and the protective effect of metformin
-
Lupi R, Del Guerra S, Fierabracci V, et al. Lipotoxicity in human pancreatic islets and the protective effect of metformin. Diabetes 2002; 51: S134-S137.
-
(2002)
Diabetes
, vol.51
-
-
Lupi, R.1
Del Guerra, S.2
Fierabracci, V.3
-
16
-
-
8744272467
-
Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin
-
Marchetti P, Del Guerra S, Marselli L, et al. Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin. J Clin Endocrinol Metab 2004; 89: 5535-5541.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 5535-5541
-
-
Marchetti, P.1
Del Guerra, S.2
Marselli, L.3
-
17
-
-
33846258421
-
Role of metformin in the initiation of pharmacotherapy for type 2 diabetes: an Asian-Pacific perspective
-
Chan JC, Deerochanawong C, Shera AS, et al. Role of metformin in the initiation of pharmacotherapy for type 2 diabetes: an Asian-Pacific perspective. Diabetes Res Clin Pract 2007; 75: 255-266.
-
(2007)
Diabetes Res Clin Pract
, vol.75
, pp. 255-266
-
-
Chan, J.C.1
Deerochanawong, C.2
Shera, A.S.3
-
18
-
-
0025800354
-
Different aetiologies of type 2 (non insulin-dependent) diabetes mellitus in obese and non-obese subjects
-
Arner P, Pollare T, Lithell H. Different aetiologies of type 2 (non insulin-dependent) diabetes mellitus in obese and non-obese subjects. Diabetologia 1991; 34: 483-487.
-
(1991)
Diabetologia
, vol.34
, pp. 483-487
-
-
Arner, P.1
Pollare, T.2
Lithell, H.3
-
19
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
-
Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 1998; 15: 539-553.
-
(1998)
Diabet Med
, vol.15
, pp. 539-553
-
-
Alberti, K.G.1
Zimmet, P.Z.2
-
20
-
-
0003922844
-
-
Steering Committee of the Western Pacific Region of the World Health Organization, the International Association for the Study of Obesity, and the International Obesity Task Force. Health Communications Australia Pty Ltd, Melbourne, Australia
-
Steering Committee of the Western Pacific Region of the World Health Organization, the International Association for the Study of Obesity, and the International Obesity Task Force. The Asia-Pacific perspective: redefining obesity and its treatment. Health Communications Australia Pty Ltd, Melbourne, Australia, 2000.
-
(2000)
The Asia-Pacific perspective: redefining obesity and its treatment
-
-
-
21
-
-
0027979127
-
A mathematical model for the determination of total area under glucose tolerance and other metabolic curves
-
Tai MM. A mathematical model for the determination of total area under glucose tolerance and other metabolic curves. Diabetes Care 1994; 17: 152-154.
-
(1994)
Diabetes Care
, vol.17
, pp. 152-154
-
-
Tai, M.M.1
-
22
-
-
84862857064
-
β-Cell function preservation after 3.5years of intensive diabetes therapy
-
Harrison LB, Adams-Huet B, Raskin P, Lingvay I. β-Cell function preservation after 3.5years of intensive diabetes therapy. Diabetes Care 2012; 35: 1406-1412.
-
(2012)
Diabetes Care
, vol.35
, pp. 1406-1412
-
-
Harrison, L.B.1
Adams-Huet, B.2
Raskin, P.3
Lingvay, I.4
-
23
-
-
0032821965
-
Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp
-
Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999; 22: 1462-1470.
-
(1999)
Diabetes Care
, vol.22
, pp. 1462-1470
-
-
Matsuda, M.1
DeFronzo, R.A.2
-
24
-
-
77949270229
-
For the ACT NOW study group. Determinants of glucose tolerance in impaired glucose tolerance at baseline in the Actos Now for Prevention of Diabetes (ACT NOW) study
-
Defronzo RA, Banerji MA, Bray GA, et al. For the ACT NOW study group. Determinants of glucose tolerance in impaired glucose tolerance at baseline in the Actos Now for Prevention of Diabetes (ACT NOW) study. Diabetologia 2010; 53: 435-445.
-
(2010)
Diabetologia
, vol.53
, pp. 435-445
-
-
Defronzo, R.A.1
Banerji, M.A.2
Bray, G.A.3
-
25
-
-
84855348576
-
Association of β-cell function and insulin sensitivity with fasting and 2h plasma glucose in a large Chinese population
-
Bi Y, Zeng LY, Zhu DL, et al. Association of β-cell function and insulin sensitivity with fasting and 2h plasma glucose in a large Chinese population. Diabetes Obes Metab 2012; 14: 174-180.
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 174-180
-
-
Bi, Y.1
Zeng, L.Y.2
Zhu, D.L.3
-
27
-
-
22344448987
-
Effects of metformin on glucagon-like peptide-1 levels in obese patients with and without type 2 diabetes
-
Mannucci E, Tesi F, Bardini G, et al. Effects of metformin on glucagon-like peptide-1 levels in obese patients with and without type 2 diabetes. Diabetes Nutr Metab 2004; 17: 336-342.
-
(2004)
Diabetes Nutr Metab
, vol.17
, pp. 336-342
-
-
Mannucci, E.1
Tesi, F.2
Bardini, G.3
-
28
-
-
84863998110
-
Effects of chronic treatment with metformin on dipeptidyl peptidase-4 activity, glucagon-like peptide 1 and Ghrelin in obese patients with type2 diabetes mellitus
-
Thondam SK, Cross A, Cuthbertson DJ, Wilding JP, Daousi C. Effects of chronic treatment with metformin on dipeptidyl peptidase-4 activity, glucagon-like peptide 1 and Ghrelin in obese patients with type2 diabetes mellitus. Diabet Med 2012; 29: e205-e210.
-
(2012)
Diabet Med
, vol.29
-
-
Thondam, S.K.1
Cross, A.2
Cuthbertson, D.J.3
Wilding, J.P.4
Daousi, C.5
-
29
-
-
0036298693
-
Metformin effects on dipeptidylpeptidase IV degradation of glucagon-like peptide-1
-
Hinke SA, Kühn-Wache K, Hoffmann T, et al. Metformin effects on dipeptidylpeptidase IV degradation of glucagon-like peptide-1. Biochem Biophys Res Commun 2002; 291: 1302-1308.
-
(2002)
Biochem Biophys Res Commun
, vol.291
, pp. 1302-1308
-
-
Hinke, S.A.1
Kühn-Wache, K.2
Hoffmann, T.3
-
30
-
-
78951479936
-
New aspects of an old drug: metformin as a glucagon-like peptide 1 (GLP-1) enhancer and sensitiser
-
Cho YM, Kieffer TJ. New aspects of an old drug: metformin as a glucagon-like peptide 1 (GLP-1) enhancer and sensitiser. Diabetologia 2011; 54: 219-222.
-
(2011)
Diabetologia
, vol.54
, pp. 219-222
-
-
Cho, Y.M.1
Kieffer, T.J.2
-
31
-
-
78951476273
-
Metformin regulates the incretin receptor axis via a pathway dependent on peroxisome proliferator-activated receptor-α in mice
-
Maida A, Lamont BJ, Cao X, Drucker DJ. Metformin regulates the incretin receptor axis via a pathway dependent on peroxisome proliferator-activated receptor-α in mice. Diabetologia 2011; 54: 339-349.
-
(2011)
Diabetologia
, vol.54
, pp. 339-349
-
-
Maida, A.1
Lamont, B.J.2
Cao, X.3
Drucker, D.J.4
-
32
-
-
0036724256
-
Glucose-sensing in glucagon-like eptide-1-secreting cells
-
Reimann F, Gribble FM. Glucose-sensing in glucagon-like eptide-1-secreting cells. Diabetes 2002; 51: 2757-2763.
-
(2002)
Diabetes
, vol.51
, pp. 2757-2763
-
-
Reimann, F.1
Gribble, F.M.2
-
33
-
-
84855459920
-
Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover
-
Unger RH, Cherrington AD. Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover. J Clin Invest 2012; 122: 4-12.
-
(2012)
J Clin Invest
, vol.122
, pp. 4-12
-
-
Unger, R.H.1
Cherrington, A.D.2
-
34
-
-
84873707522
-
Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP
-
Miller RA, Chu Q, Xie J, et al. Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP. Nature 2013; 494: 256-260.
-
(2013)
Nature
, vol.494
, pp. 256-260
-
-
Miller, R.A.1
Chu, Q.2
Xie, J.3
-
35
-
-
0032511566
-
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
-
UK Prospective Diabetes Study (UKPDS) Group.
-
UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 1998; 352: 854-865.
-
(1998)
Lancet
, vol.352
, pp. 854-865
-
-
-
36
-
-
0242535602
-
Cooperative meta-analysis group of working group on obesity in China. Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults: study on optimal cut-off points of body mass index and waist circumference in Chinese adults
-
Bei-Fan Z. Cooperative meta-analysis group of working group on obesity in China. Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults: study on optimal cut-off points of body mass index and waist circumference in Chinese adults. Asia Pac J Clin Nutr 2002; 11: S685-S693.
-
(2002)
Asia Pac J Clin Nutr
, vol.11
-
-
Bei-Fan, Z.1
|