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Volumn 24, Issue 12, 2013, Pages 2110-2118

Cardioprotective effect of selenium via modulation of cardiac ryanodine receptor calcium release channels in diabetic rat cardiomyocytes through thioredoxin system

Author keywords

Calcium calmodulin kinase; Calcium spark; Cellular redox regulation; Glutathione; Heart; Protein kinase A

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; REACTIVE OXYGEN METABOLITE; RYANODINE RECEPTOR 2; SELENATE; SELENIUM; STREPTOZOCIN; THIOREDOXIN;

EID: 84887613648     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2013.08.002     Document Type: Article
Times cited : (31)

References (62)
  • 4
    • 23844469794 scopus 로고    scopus 로고
    • Oxidative stress and stress signaling: menace of diabetic cardiomyopathy
    • Wold L.E., Ceylan-Isik A.F., Ren J. Oxidative stress and stress signaling: menace of diabetic cardiomyopathy. Acta Pharmacol Sin 2005, 26(8):908-917.
    • (2005) Acta Pharmacol Sin , vol.26 , Issue.8 , pp. 908-917
    • Wold, L.E.1    Ceylan-Isik, A.F.2    Ren, J.3
  • 5
    • 0039483044 scopus 로고    scopus 로고
    • Changes in antioxidant status of heart muscle tissue in experimental diabetes in rabbits
    • Gumieniczek A., Hopkala H., Wojtowicz Z., Nikolajuk J. Changes in antioxidant status of heart muscle tissue in experimental diabetes in rabbits. Acta Biochim Pol 2002, 49(2):529-535.
    • (2002) Acta Biochim Pol , vol.49 , Issue.2 , pp. 529-535
    • Gumieniczek, A.1    Hopkala, H.2    Wojtowicz, Z.3    Nikolajuk, J.4
  • 6
    • 0035237261 scopus 로고    scopus 로고
    • Redox control of cellular function by thioredoxin; a new therapeutic direction in host defence
    • Nishinaka Y., Nakamura H., Masutani H., Yodoi J. Redox control of cellular function by thioredoxin; a new therapeutic direction in host defence. Arch Immunol Ther Exp (Warsz) 2001, 49(4):285-292.
    • (2001) Arch Immunol Ther Exp (Warsz) , vol.49 , Issue.4 , pp. 285-292
    • Nishinaka, Y.1    Nakamura, H.2    Masutani, H.3    Yodoi, J.4
  • 7
    • 0023576328 scopus 로고
    • Alterations in free radical tissue-defense mechanisms in streptozocin-induced diabetes in rat. Effects of insulin treatment
    • Wohaieb S.A., Godin D.V. Alterations in free radical tissue-defense mechanisms in streptozocin-induced diabetes in rat. Effects of insulin treatment. Diabetes 1987, 36(9):1014-1018.
    • (1987) Diabetes , vol.36 , Issue.9 , pp. 1014-1018
    • Wohaieb, S.A.1    Godin, D.V.2
  • 8
    • 33645740498 scopus 로고    scopus 로고
    • Selenium prevents diabetes-induced alterations in [zn2+]i and metallothionein level of rat heart via restoration of cell redox cycle
    • Ayaz M., Turan B. Selenium prevents diabetes-induced alterations in [zn2+]i and metallothionein level of rat heart via restoration of cell redox cycle. Am J Physiol Heart Circ Physiol 2006, 290(3):H1071-H1080.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , Issue.3
    • Ayaz, M.1    Turan, B.2
  • 9
    • 33644677758 scopus 로고    scopus 로고
    • Effects of diabetes on ryanodine receptor ca release channel (ryr2) and ca2+ homeostasis in rat heart
    • Yaras N., Ugur M., Ozdemir S., Gurdal H., Purali N., Lacampagne A., Vassort G., Turan B. Effects of diabetes on ryanodine receptor ca release channel (ryr2) and ca2+ homeostasis in rat heart. Diabetes 2005, 54(11):3082-3088.
    • (2005) Diabetes , vol.54 , Issue.11 , pp. 3082-3088
    • Yaras, N.1    Ugur, M.2    Ozdemir, S.3    Gurdal, H.4    Purali, N.5    Lacampagne, A.6    Vassort, G.7    Turan, B.8
  • 10
    • 44949122716 scopus 로고    scopus 로고
    • Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases
    • Bjelakovic G., Nikolova D., Gluud L.L., Simonetti R.G., Gluud C. Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases. Cochrane Database Syst Rev 2008, (2):CD007176.
    • (2008) Cochrane Database Syst Rev , Issue.2
    • Bjelakovic, G.1    Nikolova, D.2    Gluud, L.L.3    Simonetti, R.G.4    Gluud, C.5
  • 11
    • 0035430412 scopus 로고    scopus 로고
    • Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve
    • Coppey L.J., Gellett J.S., Davidson E.P., Dunlap J.A., Lund D.D., Yorek M.A. Effect of antioxidant treatment of streptozotocin-induced diabetic rats on endoneurial blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve. Diabetes 2001, 50(8):1927-1937.
    • (2001) Diabetes , vol.50 , Issue.8 , pp. 1927-1937
    • Coppey, L.J.1    Gellett, J.S.2    Davidson, E.P.3    Dunlap, J.A.4    Lund, D.D.5    Yorek, M.A.6
  • 12
    • 4043086365 scopus 로고    scopus 로고
    • Rationale and design of the gissi heart failure trial: a large trial to assess the effects of n-3 polyunsaturated fatty acids and rosuvastatin in symptomatic congestive heart failure
    • Tavazzi L., Tognoni G., Franzosi M.G., Latini R., Maggioni A.P., Marchioli R., Nicolosi G.L., Porcu M., Investigators G.-H. Rationale and design of the gissi heart failure trial: a large trial to assess the effects of n-3 polyunsaturated fatty acids and rosuvastatin in symptomatic congestive heart failure. Eur J Heart Fail 2004, 6(5):635-641.
    • (2004) Eur J Heart Fail , vol.6 , Issue.5 , pp. 635-641
    • Tavazzi, L.1    Tognoni, G.2    Franzosi, M.G.3    Latini, R.4    Maggioni, A.P.5    Marchioli, R.6    Nicolosi, G.L.7    Porcu, M.8    Investigators, G.-H.9
  • 13
  • 14
    • 19444381651 scopus 로고    scopus 로고
    • Direct association of hepatopoietin with thioredoxin constitutes a redox signal transduction in activation of ap-1/nf-kappab
    • Li Y., Liu W., Xing G., Tian C., Zhu Y., He F. Direct association of hepatopoietin with thioredoxin constitutes a redox signal transduction in activation of ap-1/nf-kappab. Cell Signal 2005, 17(8):985-996.
    • (2005) Cell Signal , vol.17 , Issue.8 , pp. 985-996
    • Li, Y.1    Liu, W.2    Xing, G.3    Tian, C.4    Zhu, Y.5    He, F.6
  • 15
    • 18244390482 scopus 로고    scopus 로고
    • Beneficial effects of selenium on some enzymes of diabetic rat heart
    • Ulusu N.N., Turan B. Beneficial effects of selenium on some enzymes of diabetic rat heart. Biol Trace Elem Res 2005, 103(3):207-216.
    • (2005) Biol Trace Elem Res , vol.103 , Issue.3 , pp. 207-216
    • Ulusu, N.N.1    Turan, B.2
  • 16
    • 2342661187 scopus 로고    scopus 로고
    • Effects of selenium on altered mechanical and electrical cardiac activities of diabetic rat
    • Ayaz M., Ozdemir S., Ugur M., Vassort G., Turan B. Effects of selenium on altered mechanical and electrical cardiac activities of diabetic rat. Arch Biochem Biophys 2004, 426(1):83-90.
    • (2004) Arch Biochem Biophys , vol.426 , Issue.1 , pp. 83-90
    • Ayaz, M.1    Ozdemir, S.2    Ugur, M.3    Vassort, G.4    Turan, B.5
  • 17
    • 0033837781 scopus 로고    scopus 로고
    • Thiol homeostasis and supplements in physical exercise
    • Sen C.K., Packer L. Thiol homeostasis and supplements in physical exercise. Am J Clin Nutr 2000, 72(2 Suppl):653S-669S.
    • (2000) Am J Clin Nutr , vol.72 , Issue.2 SUPPL
    • Sen, C.K.1    Packer, L.2
  • 18
    • 0031589552 scopus 로고    scopus 로고
    • Glutathione regulation of tumor necrosis factor-alpha-induced nf-kappa b activation in skeletal muscle-derived l6 cells
    • Sen C.K., Khanna S., Reznick A.Z., Roy S., Packer L. Glutathione regulation of tumor necrosis factor-alpha-induced nf-kappa b activation in skeletal muscle-derived l6 cells. Biochem Biophys Res Commun 1997, 237(3):645-649.
    • (1997) Biochem Biophys Res Commun , vol.237 , Issue.3 , pp. 645-649
    • Sen, C.K.1    Khanna, S.2    Reznick, A.Z.3    Roy, S.4    Packer, L.5
  • 19
    • 34648816994 scopus 로고    scopus 로고
    • Gender related differential effects of omega-3e treatment on diabetes-induced left ventricular dysfunction
    • Tuncay E., Seymen A.A., Tanriverdi E., Yaras N., Tandogan B., Ulusu N.N., Turan B. Gender related differential effects of omega-3e treatment on diabetes-induced left ventricular dysfunction. Mol Cell Biochem 2007, 304(1-2):255-263.
    • (2007) Mol Cell Biochem , vol.304 , Issue.1-2 , pp. 255-263
    • Tuncay, E.1    Seymen, A.A.2    Tanriverdi, E.3    Yaras, N.4    Tandogan, B.5    Ulusu, N.N.6    Turan, B.7
  • 20
    • 67650257495 scopus 로고    scopus 로고
    • High glucose sensitizes adult cardiomyocytes to ischaemia/reperfusion injury through nitrative thioredoxin inactivation
    • Luan R., Liu S., Yin T., Lau W.B., Wang Q., Guo W., Wang H., Tao L. High glucose sensitizes adult cardiomyocytes to ischaemia/reperfusion injury through nitrative thioredoxin inactivation. Cardiovasc Res 2009, 83(2):294-302.
    • (2009) Cardiovasc Res , vol.83 , Issue.2 , pp. 294-302
    • Luan, R.1    Liu, S.2    Yin, T.3    Lau, W.B.4    Wang, Q.5    Guo, W.6    Wang, H.7    Tao, L.8
  • 22
    • 17144413032 scopus 로고    scopus 로고
    • Effects of a supranutritional dose of selenate compared with selenite on insulin sensitivity in type II diabetic dbdb mice
    • Muller A.S., Most E., Pallauf J. Effects of a supranutritional dose of selenate compared with selenite on insulin sensitivity in type II diabetic dbdb mice. J Anim Physiol Anim Nutr (Berl) 2005, 89(3-6):94-104.
    • (2005) J Anim Physiol Anim Nutr (Berl) , vol.89 , Issue.3-6 , pp. 94-104
    • Muller, A.S.1    Most, E.2    Pallauf, J.3
  • 24
    • 33749505491 scopus 로고    scopus 로고
    • Biphasic modulation of ryanodine receptors by sulfhydryl oxidation in rat ventricular myocytes
    • Xie H., Zhu P.H. Biphasic modulation of ryanodine receptors by sulfhydryl oxidation in rat ventricular myocytes. Biophys J 2006, 91(8):2882-2891.
    • (2006) Biophys J , vol.91 , Issue.8 , pp. 2882-2891
    • Xie, H.1    Zhu, P.H.2
  • 25
    • 33745198418 scopus 로고    scopus 로고
    • Redox regulation of cardiac calcium channels and transporters
    • Zima A.V., Blatter L.A. Redox regulation of cardiac calcium channels and transporters. Cardiovasc Res 2006, 71(2):310-321.
    • (2006) Cardiovasc Res , vol.71 , Issue.2 , pp. 310-321
    • Zima, A.V.1    Blatter, L.A.2
  • 30
    • 77955841993 scopus 로고    scopus 로고
    • Antioxidant treatment protects diabetic rats from cardiac dysfunction by preserving contractile protein targets of oxidative stress
    • Aydemir-Koksoy A., Bilginoglu A., Sariahmetoglu M., Schulz R., Turan B. Antioxidant treatment protects diabetic rats from cardiac dysfunction by preserving contractile protein targets of oxidative stress. J Nutr Biochem 2010, 21(9):827-833.
    • (2010) J Nutr Biochem , vol.21 , Issue.9 , pp. 827-833
    • Aydemir-Koksoy, A.1    Bilginoglu, A.2    Sariahmetoglu, M.3    Schulz, R.4    Turan, B.5
  • 31
    • 79960777814 scopus 로고    scopus 로고
    • Profound cardioprotection with timolol in a female rat model of aging-related altered left ventricular function
    • Sozmen N.N., Tuncay E., Bilginoglu A., Turan B. Profound cardioprotection with timolol in a female rat model of aging-related altered left ventricular function. Can J Physiol Pharmacol 2011, 89(4):277-288.
    • (2011) Can J Physiol Pharmacol , vol.89 , Issue.4 , pp. 277-288
    • Sozmen, N.N.1    Tuncay, E.2    Bilginoglu, A.3    Turan, B.4
  • 32
    • 84857053110 scopus 로고    scopus 로고
    • Cardioprotective effect of propranolol on diabetes-induced altered intracellular ca2+ signaling in rat
    • Tuncay E., Zeydanli E.N., Turan B. Cardioprotective effect of propranolol on diabetes-induced altered intracellular ca2+ signaling in rat. J Bioenerg Biomembr 2011, 43(6):747-756.
    • (2011) J Bioenerg Biomembr , vol.43 , Issue.6 , pp. 747-756
    • Tuncay, E.1    Zeydanli, E.N.2    Turan, B.3
  • 33
    • 0028619963 scopus 로고
    • The analysis of free radicals, lipid peroxides, antioxidant enzymes and compounds related to oxidative stress as applied to the clinical chemistry laboratory
    • Armstrong D., Browne R. The analysis of free radicals, lipid peroxides, antioxidant enzymes and compounds related to oxidative stress as applied to the clinical chemistry laboratory. Adv Exp Med Biol 1994, 366:43-58.
    • (1994) Adv Exp Med Biol , vol.366 , pp. 43-58
    • Armstrong, D.1    Browne, R.2
  • 34
    • 0032824908 scopus 로고    scopus 로고
    • Induction of thioredoxin, thioredoxin reductase and glutaredoxin activity in mouse skin by tpa, a calcium ionophore and other tumor promoters
    • Kumar S., Holmgren A. Induction of thioredoxin, thioredoxin reductase and glutaredoxin activity in mouse skin by tpa, a calcium ionophore and other tumor promoters. Carcinogenesis 1999, 20(9):1761-1767.
    • (1999) Carcinogenesis , vol.20 , Issue.9 , pp. 1761-1767
    • Kumar, S.1    Holmgren, A.2
  • 35
    • 0036890289 scopus 로고    scopus 로고
    • Protective effect of selenium treatment on diabetes-induced myocardial structural alterations
    • Ayaz M., Can B., Ozdemir S., Turan B. Protective effect of selenium treatment on diabetes-induced myocardial structural alterations. Biol Trace Elem Res 2002, 89(3):215-226.
    • (2002) Biol Trace Elem Res , vol.89 , Issue.3 , pp. 215-226
    • Ayaz, M.1    Can, B.2    Ozdemir, S.3    Turan, B.4
  • 36
    • 33845657896 scopus 로고    scopus 로고
    • Dyssynchronous (non-uniform) ca2+ release in myocytes from streptozotocin-induced diabetic rats
    • Shao C.H., Rozanski G.J., Patel K.P., Bidasee K.R. Dyssynchronous (non-uniform) ca2+ release in myocytes from streptozotocin-induced diabetic rats. J Mol Cell Cardiol 2007, 42(1):234-246.
    • (2007) J Mol Cell Cardiol , vol.42 , Issue.1 , pp. 234-246
    • Shao, C.H.1    Rozanski, G.J.2    Patel, K.P.3    Bidasee, K.R.4
  • 37
    • 74249092946 scopus 로고    scopus 로고
    • Nf-kappab-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes
    • Mariappan N., Elks C.M., Sriramula S., Guggilam A., Liu Z., Borkhsenious O., Francis J. Nf-kappab-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes. Cardiovasc Res 2010, 85(3):473-483.
    • (2010) Cardiovasc Res , vol.85 , Issue.3 , pp. 473-483
    • Mariappan, N.1    Elks, C.M.2    Sriramula, S.3    Guggilam, A.4    Liu, Z.5    Borkhsenious, O.6    Francis, J.7
  • 38
    • 24144502073 scopus 로고    scopus 로고
    • Selenium improves cardiac function by attenuating the activation of NF-kappab due to ischemia-reperfusion injury
    • Turan B., Saini H.K., Zhang M., Prajapati D., Elimban V., Dhalla N.S. Selenium improves cardiac function by attenuating the activation of NF-kappab due to ischemia-reperfusion injury. Antioxid Redox Signal 2005, 7(9-10):1388-1397.
    • (2005) Antioxid Redox Signal , vol.7 , Issue.9-10 , pp. 1388-1397
    • Turan, B.1    Saini, H.K.2    Zhang, M.3    Prajapati, D.4    Elimban, V.5    Dhalla, N.S.6
  • 39
    • 15444377306 scopus 로고    scopus 로고
    • Thioredoxin: a multifunctional antioxidant enzyme in kidney, heart and vessels
    • Yamawaki H., Berk B.C. Thioredoxin: a multifunctional antioxidant enzyme in kidney, heart and vessels. Curr Opin Nephrol Hypertens 2005, 14(2):149-153.
    • (2005) Curr Opin Nephrol Hypertens , vol.14 , Issue.2 , pp. 149-153
    • Yamawaki, H.1    Berk, B.C.2
  • 40
    • 34147198734 scopus 로고    scopus 로고
    • Thioredoxin in the cardiovascular system
    • World C.J., Yamawaki H., Berk B.C. Thioredoxin in the cardiovascular system. J Mol Med (Berl) 2006, 84(12):997-1003.
    • (2006) J Mol Med (Berl) , vol.84 , Issue.12 , pp. 997-1003
    • World, C.J.1    Yamawaki, H.2    Berk, B.C.3
  • 41
    • 0036283762 scopus 로고    scopus 로고
    • Thermodynamically irreversible gating of ryanodine receptors in situ revealed by stereotyped duration of release in ca(2+) sparks
    • Wang S.Q., Song L.S., Xu L., Meissner G., Lakatta E.G., Rios E., Stern M.D., Cheng H. Thermodynamically irreversible gating of ryanodine receptors in situ revealed by stereotyped duration of release in ca(2+) sparks. Biophys J 2002, 83(1):242-251.
    • (2002) Biophys J , vol.83 , Issue.1 , pp. 242-251
    • Wang, S.Q.1    Song, L.S.2    Xu, L.3    Meissner, G.4    Lakatta, E.G.5    Rios, E.6    Stern, M.D.7    Cheng, H.8
  • 42
    • 23844456403 scopus 로고    scopus 로고
    • Abnormal ryanodine receptor function in heart failure
    • Yano M., Yamamoto T., Ikemoto N., Matsuzaki M. Abnormal ryanodine receptor function in heart failure. Pharmacol Ther 2005, 107(3):377-391.
    • (2005) Pharmacol Ther , vol.107 , Issue.3 , pp. 377-391
    • Yano, M.1    Yamamoto, T.2    Ikemoto, N.3    Matsuzaki, M.4
  • 45
    • 80155123422 scopus 로고    scopus 로고
    • Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis
    • Kain V., Kumar S., Sitasawad S.L. Azelnidipine prevents cardiac dysfunction in streptozotocin-diabetic rats by reducing intracellular calcium accumulation, oxidative stress and apoptosis. Cardiovasc Diabetol 2011, 10:97.
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 97
    • Kain, V.1    Kumar, S.2    Sitasawad, S.L.3
  • 46
  • 47
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • Baynes J.W. Role of oxidative stress in development of complications in diabetes. Diabetes 1991, 40(4):405-412.
    • (1991) Diabetes , vol.40 , Issue.4 , pp. 405-412
    • Baynes, J.W.1
  • 48
    • 0036665229 scopus 로고    scopus 로고
    • Oxidative stress, nitric oxide, and vascular disease
    • Jeremy J.Y., Yim A.P., Wan S., Angelini G.D. Oxidative stress, nitric oxide, and vascular disease. J Card Surg 2002, 17(4):324-327.
    • (2002) J Card Surg , vol.17 , Issue.4 , pp. 324-327
    • Jeremy, J.Y.1    Yim, A.P.2    Wan, S.3    Angelini, G.D.4
  • 49
    • 22444444913 scopus 로고    scopus 로고
    • Selenium treatment protects diabetes-induced biochemical and ultrastructural alterations in liver tissue
    • Can B., Ulusu N.N., Kilinc K., Leyla Acan N., Saran Y., Turan B. Selenium treatment protects diabetes-induced biochemical and ultrastructural alterations in liver tissue. Biol Trace Elem Res 2005, 105(1-3):135-150.
    • (2005) Biol Trace Elem Res , vol.105 , Issue.1-3 , pp. 135-150
    • Can, B.1    Ulusu, N.N.2    Kilinc, K.3    Leyla Acan, N.4    Saran, Y.5    Turan, B.6
  • 50
    • 0031908442 scopus 로고    scopus 로고
    • Sodium selenate corrects glucose tolerance and heart function in STZ diabetic rats
    • Battell M.L., Delgatty H.L., Mcneill J.H. Sodium selenate corrects glucose tolerance and heart function in STZ diabetic rats. Mol Cell Biochem 1998, 179(1-2):27-34.
    • (1998) Mol Cell Biochem , vol.179 , Issue.1-2 , pp. 27-34
    • Battell, M.L.1    Delgatty, H.L.2    Mcneill, J.H.3
  • 51
    • 0029563153 scopus 로고
    • Insulin-like effects of vanadate and selenate on the expression of glucose-6-phosphate dehydrogenase and fatty acid synthase in diabetic rats
    • Berg E.A., Wu J.Y., Campbell L., Kagey M., Stapleton S.R. Insulin-like effects of vanadate and selenate on the expression of glucose-6-phosphate dehydrogenase and fatty acid synthase in diabetic rats. Biochimie 1995, 77(12):919-924.
    • (1995) Biochimie , vol.77 , Issue.12 , pp. 919-924
    • Berg, E.A.1    Wu, J.Y.2    Campbell, L.3    Kagey, M.4    Stapleton, S.R.5
  • 53
    • 49349099323 scopus 로고    scopus 로고
    • Emerging potential of thioredoxin and thioredoxin interacting proteins in various disease conditions
    • Maulik N., Das D.K. Emerging potential of thioredoxin and thioredoxin interacting proteins in various disease conditions. Biochim Biophys Acta 2008, 1780(11):1368-1382.
    • (2008) Biochim Biophys Acta , vol.1780 , Issue.11 , pp. 1368-1382
    • Maulik, N.1    Das, D.K.2
  • 54
    • 35348814361 scopus 로고    scopus 로고
    • Effect of selenium on thioredoxin reductase activity in txnrd1 or txnrd2 hemizygous mice
    • Kiermayer C., Michalke B., Schmidt J., Brielmeier M. Effect of selenium on thioredoxin reductase activity in txnrd1 or txnrd2 hemizygous mice. Biol Chem 2007, 388(10):1091-1097.
    • (2007) Biol Chem , vol.388 , Issue.10 , pp. 1091-1097
    • Kiermayer, C.1    Michalke, B.2    Schmidt, J.3    Brielmeier, M.4
  • 55
    • 24344446442 scopus 로고    scopus 로고
    • Effect of selenium-supplement on the calcium signaling in human endothelial cells
    • Zheng Y., Zhong L., Shen X. Effect of selenium-supplement on the calcium signaling in human endothelial cells. J Cell Physiol 2005, 205(1):97-106.
    • (2005) J Cell Physiol , vol.205 , Issue.1 , pp. 97-106
    • Zheng, Y.1    Zhong, L.2    Shen, X.3
  • 56
    • 79957977089 scopus 로고    scopus 로고
    • Restoration of cardiomyocyte function in streptozotocin-induced diabetic rats after treatment with vanadate in a tea decoction
    • Clark T.A., Maddaford T.G., Tappia P.S., Heyliger C.E., Ganguly P.K., Pierce G.N. Restoration of cardiomyocyte function in streptozotocin-induced diabetic rats after treatment with vanadate in a tea decoction. Curr Pharm Biotechnol 2010, 11(8):906-910.
    • (2010) Curr Pharm Biotechnol , vol.11 , Issue.8 , pp. 906-910
    • Clark, T.A.1    Maddaford, T.G.2    Tappia, P.S.3    Heyliger, C.E.4    Ganguly, P.K.5    Pierce, G.N.6
  • 58
    • 0021991110 scopus 로고
    • Effect of vanadate on elevated blood glucose and depressed cardiac performance of diabetic rats
    • Heyliger C.E., Tahiliani A.G., Mcneill J.H. Effect of vanadate on elevated blood glucose and depressed cardiac performance of diabetic rats. Science 1985, 227(4693):1474-1477.
    • (1985) Science , vol.227 , Issue.4693 , pp. 1474-1477
    • Heyliger, C.E.1    Tahiliani, A.G.2    Mcneill, J.H.3
  • 60
    • 33847640513 scopus 로고    scopus 로고
    • Thiol-related genes in diabetic complications: a novel protective role for endogenous thioredoxin 2
    • Liang M., Pietrusz J.L. Thiol-related genes in diabetic complications: a novel protective role for endogenous thioredoxin 2. Arterioscler Thromb Vasc Biol 2007, 27(1):77-83.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , Issue.1 , pp. 77-83
    • Liang, M.1    Pietrusz, J.L.2
  • 61
    • 0029070687 scopus 로고
    • Alpha-lipoic acid as a biological antioxidant
    • Packer L., Witt E.H., Tritschler H.J. Alpha-lipoic acid as a biological antioxidant. Free Radic Biol Med 1995, 19(2):227-250.
    • (1995) Free Radic Biol Med , vol.19 , Issue.2 , pp. 227-250
    • Packer, L.1    Witt, E.H.2    Tritschler, H.J.3
  • 62
    • 77956255433 scopus 로고    scopus 로고
    • Pkc alpha phosphorylates cytosolic nf-kappab/p65 and pkc delta delays nuclear translocation of nf-kappab/p65 in u1242 glioblastoma cells
    • Mut M., Amos S., Hussaini I.M. Pkc alpha phosphorylates cytosolic nf-kappab/p65 and pkc delta delays nuclear translocation of nf-kappab/p65 in u1242 glioblastoma cells. Turk Neurosurg 2010, 20(3):277-285.
    • (2010) Turk Neurosurg , vol.20 , Issue.3 , pp. 277-285
    • Mut, M.1    Amos, S.2    Hussaini, I.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.