Comparison of transduction efficiency among various lentiviruses containing GFP reporter in bone marrow hematopoietic stem cell transplantation

Experimental Hematology

Volumn 41, Issue 11, 2013, Pages 934-943

  Wang, Nan ^a   Rajasekaran, Narendiran ^a   Hou, Tieying ^a   Lisowski, Leszek ^a   Mellins, Elizabeth D ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; ELONGATION FACTOR 1ALPHA; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN II; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; GENE EXPRESSION; GFP GENE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; II GENE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INDUCTION; TRANSGENE; TRANSIENT TRANSFECTION; VIRAL GENE DELIVERY SYSTEM; VIRUS INDUCTION;

ANIMALS; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; BONE MARROW; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; LENTIVIRUS; MICE; MICE, INBRED NOD; PEPTIDE ELONGATION FACTOR 1; PROMOTER REGIONS, GENETIC; RETROVIRIDAE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSDUCTION, GENETIC;

LENTIVIRUS; MURINAE;

EID: 84887611242     PISSN: 0301472X     EISSN: 18732399     Source Type: Journal    
DOI: 10.1016/j.exphem.2013.07.002     Document Type: Article

References (33)

1. Hu B., Tai A., Wang P. Immunization delivered by lentiviral vectors for cancer and infectious diseases. Immunol Rev 2011, 239:45-61.
2. Barrette S., Douglas J.L., Seidel N.E., Bodine D.M. Lentivirus-based vectors transduce mouse hematopoietic stem cells with similar efficiency to moloney murine leukemia virus-based vectors. Blood 2000, 96:3385-3391.
3. Bank A. Hematopoietic stem cell gene therapy: selecting only the best. J Clin Invest 2003, 112:1478-1480.
4. Wanisch K., Yanez-Munoz R.J. Integration-deficient lentiviral vectors: a slow coming of age. Mol Ther 2009, 17:1316-1332.
5. Leuci V., Mesiano G., Gammaitoni L., et al. Transient proteasome inhibition as a strategy to enhance lentiviral transduction of hematopoietic CD34(+) cells and T lymphocytes: implications for the use of low viral doses and large-size vectors. J Biotechnol 2011, 156:218-226.
6. Liu Y., Hangoc G., Campbell T.B., et al. Identification of parameters required for efficient lentiviral vector transduction and engraftment of human cord blood CD34(+) NOD/SCID-repopulating cells. Exp Hematol 2008, 36:947-956.
7. de Felipe P. Polycistronic viral vectors. Curr Gene Ther 2002, 2:355-378.
8. Yu X., Zhan X., D'Costa J., et al. Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Mol Ther 2003, 7:827-838.
9. Szymczak-Workman A.L., Vignali K.M., Vignali D.A. Design and construction of 2A peptide-linked multicistronic vectors. Cold Spring Harb Protoc 2012, 2012:199-204.
10. Tian J., Andreadis S.T. Independent and high-level dual-gene expression in adult stem-progenitor cells from a single lentiviral vector. Gene Ther 2009, 16:874-884.
11. Sitnicka E., Buza-Vidas N., Larsson S., Nygren J.M., Liuba K., Jacobsen S.E. Human CD34(+) hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic stem cells. Blood 2003, 102:881-886.
12. Rinderknecht C.H., Lu N., Crespo O., et al. I-Ag7 is subject to post-translational chaperoning by CLIP. Int Immunol 2010, 22:705-716.
13. Varma N.R., Janic B., Ali M.M., Iskander A., Arbab A.S. Lentiviral based gene transduction and promoter studies in human hematopoietic stem cells (hHSCs). J Stem Cells Regen Med 2011, 7:41-53.
14. Ramezani A., Hawley T.S., Hawley R.G. Lentiviral vectors for enhanced gene expression in human hematopoietic cells. Mol Ther 2000, 2:458-469.
15. Kutner R.H., Zhang X.Y., Reiser J. Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors. Nat Protoc 2009, 4:495-505.
16. Rajasekaran N., Wang N., Truong P., et al. Host-derived CD4(+) T cells attenuate stem cell-mediated transfer of autoimmune arthritis in lethally irradiated C57BL/6.g7 mice. Arthritis Rheum 2013, 65:681-692.
17. Lu R., Neff N.F., Quake S.R., Weissman I.L. Tracking single hematopoietic stem cells invivo using high-throughput sequencing in conjunction with viral genetic barcoding. Nat Biotechnol 2011, 29:928-933.
18. Suri A., Walters J.J., Gross M.L., Unanue E.R. Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity. J Clin Invest 2005, 115:2268-2276.
19. Hausmann D.H., Yu B., Hausmann S., Wucherpfennig K.W. pH-dependent peptide binding properties of the type I diabetes-associated I-Ag7 molecule: rapid release of CLIP at an endosomal pH. J Exp Med 1999, 189:1723-1734.
20. Curtin J.A., Dane A.P., Swanson A., Alexander I.E., Ginn S.L. Bidirectional promoter interference between two widely used internal heterologous promoters in a late-generation lentiviral construct. Gene Ther 2008, 15:384-390.
21. Choi J.K., Hoang N., Vilardi A.M., Conrad P., Emerson S.G., Gewirtz A.M. Hybrid HIV/MSCV LTR enhances transgene expression of lentiviral vectors in human CD34(+) hematopoietic cells. Stem Cells 2001, 19:236-246.
22. Swindle C.S., Kim H.G., Klug C.A. Mutation of CpGs in the murine stem cell virus retroviral vector long terminal repeat represses silencing in embryonic stem cells. J Biol Chem 2004, 279:34-41.
23. Steptoe R.J., Ritchie J.M., Harrison L.C. Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes. J Clin Invest 2003, 111:1357-1363.
24. Buchschacher G.L., Wong-Staal F. Development of lentiviral vectors for gene therapy for human diseases. Blood 2000, 95:2499-2504.
25. Frimpong K., Spector S.A. Cotransduction of nondividing cells using lentiviral vectors. Gene Ther 2000, 7:1562-1569.
26. Virology Chicurel M. Probing HIV's elusive activities within the host cell. Science 2000, 290:1876-1879.
27. Ellis J. Silencing and variegation of gammaretrovirus and lentivirus vectors. Hum Gene Ther 2005, 16:1241-1246.
28. Pannell D., Ellis J. Silencing of gene expression: implications for design of retrovirus vectors. Rev Med Virol 2001, 11:205-217.
29. Schlesinger S., Goff S.P. Silencing of proviruses in embryonic cells: efficiency, stability and chromatin modifications. EMBO Rep 2013, 14:73-79.
30. Klug C.A., Cheshier S., Weissman I.L. Inactivation of a GFP retrovirus occurs at multiple levels in long-term repopulating stem cells and their differentiated progeny. Blood 2000, 96:894-901.
31. Yamagata Y., Parietti V., Stockholm D., et al. Lentiviral transduction of CD34(+) cells induces genome-wide epigenetic modifications. PLoS One 2012, 7:e48943.
32. Cui Y., Golob J., Kelleher E., Ye Z., Pardoll D., Cheng L. Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Blood 2002, 99:399-408.
33. Moreno-Carranza B., Gentsch M., Stein S., et al. Transgene optimization significantly improves SIN vector titers, gp91phox expression and reconstitution of superoxide production in X-CGD cells. Gene Ther 2009, 16:111-118.