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Volumn 59, Issue , 2014, Pages 20-27

Genome-wide association study for radiographic vertebral fractures: A potential role for the 16q24 BMD locus

(54)  Oei, Ling a,b   Estrada, Karol a,b   Duncan, Emma L c,d   Christiansen, Claus e   Liu, Ching Ti f   Langdahl, Bente L g   Obermayer Pietsch, Barbara h   Riancho, José A i,j   Prince, Richard L k,l   van Schoor, Natasja M m   McCloskey, Eugene n,o   Hsu, Yi Hsiang p,q   Evangelou, Evangelos r,s   Ntzani, Evangelia r   Evans, David M t   Alonso, Nerea u   Husted, Lise B g   Valero, Carmen i,j   Hernandez, Jose L i,j   Lewis, Joshua R k,l   more..


Author keywords

FOXC2; GEFOS consortium; Genetics of osteoporosis; Genome wide association study; Vertebral fracture risk

Indexed keywords

ADULT; AGED; AGING; ALLELE; ARTICLE; BONE DENSITY; CHROMOSOME 16Q; CONTROLLED STUDY; FEMALE; FOXC2 GENE; FRAGILITY FRACTURE; GENE; GENE CLUSTER; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC TRAIT; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MARKER GENE; PHENOTYPE; RADIOGRAPHIC VERTEBRAL FRACTURE; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; SPINE FRACTURE;

EID: 84887568962     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2013.10.015     Document Type: Article
Times cited : (29)

References (86)
  • 2
    • 24644524544 scopus 로고    scopus 로고
    • Vertebral compression fractures in primary care: recommendations from a consensus panel
    • Brunton S., Carmichael B., Gold D., Hull B., Kauffman T., Papaioannou A., et al. Vertebral compression fractures in primary care: recommendations from a consensus panel. J Fam Pract 2005, 54:781-788.
    • (2005) J Fam Pract , vol.54 , pp. 781-788
    • Brunton, S.1    Carmichael, B.2    Gold, D.3    Hull, B.4    Kauffman, T.5    Papaioannou, A.6
  • 3
    • 33746469492 scopus 로고    scopus 로고
    • Incidence and risk factors for vertebral fracture in women and men: 25-year follow-up results from the population-based Framingham study
    • Samelson E.J., Hannan M.T., Zhang Y., Genant H.K., Felson D.T., Kiel D.P. Incidence and risk factors for vertebral fracture in women and men: 25-year follow-up results from the population-based Framingham study. J Bone Miner Res 2006, 21:1207-1214.
    • (2006) J Bone Miner Res , vol.21 , pp. 1207-1214
    • Samelson, E.J.1    Hannan, M.T.2    Zhang, Y.3    Genant, H.K.4    Felson, D.T.5    Kiel, D.P.6
  • 5
    • 0036128572 scopus 로고    scopus 로고
    • Incidence of vertebral fracture in Europe: results from the European Prospective Osteoporosis Study (EPOS)
    • Incidence of vertebral fracture in Europe: results from the European Prospective Osteoporosis Study (EPOS). J Bone Miner Res 2002, 17:716-724.
    • (2002) J Bone Miner Res , vol.17 , pp. 716-724
  • 7
    • 0030884058 scopus 로고    scopus 로고
    • Clinical consequences of vertebral fractures
    • [discussion 42S-43S]
    • Ross P.D. Clinical consequences of vertebral fractures. Am J Med 1997, 103:30S-42S. [discussion 42S-43S].
    • (1997) Am J Med , vol.103
    • Ross, P.D.1
  • 8
    • 0032524460 scopus 로고    scopus 로고
    • The association of radiographically detected vertebral fractures with back pain and function: a prospective study
    • Nevitt M.C., Ettinger B., Black D.M., Stone K., Jamal S.A., Ensrud K., et al. The association of radiographically detected vertebral fractures with back pain and function: a prospective study. Ann Intern Med 1998, 128:793-800.
    • (1998) Ann Intern Med , vol.128 , pp. 793-800
    • Nevitt, M.C.1    Ettinger, B.2    Black, D.M.3    Stone, K.4    Jamal, S.A.5    Ensrud, K.6
  • 9
    • 0029942682 scopus 로고    scopus 로고
    • The clinical impact of vertebral fractures: quality of life in women with osteoporosis
    • Gold D.T. The clinical impact of vertebral fractures: quality of life in women with osteoporosis. Bone 1996, 18:185S-189S.
    • (1996) Bone , vol.18
    • Gold, D.T.1
  • 10
    • 0034046985 scopus 로고    scopus 로고
    • Health-related quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures
    • Oleksik A., Lips P., Dawson A., Minshall M.E., Shen W., Cooper C., et al. Health-related quality of life in postmenopausal women with low BMD with or without prevalent vertebral fractures. J Bone Miner Res 2000, 15:1384-1392.
    • (2000) J Bone Miner Res , vol.15 , pp. 1384-1392
    • Oleksik, A.1    Lips, P.2    Dawson, A.3    Minshall, M.E.4    Shen, W.5    Cooper, C.6
  • 11
    • 23744497660 scopus 로고    scopus 로고
    • Impact of incident vertebral fractures on health related quality of life (HRQOL) in postmenopausal women with prevalent vertebral fractures
    • Oleksik A.M., Ewing S., Shen W., van Schoor N.M., Lips P. Impact of incident vertebral fractures on health related quality of life (HRQOL) in postmenopausal women with prevalent vertebral fractures. Osteoporos Int 2005, 16:861-870.
    • (2005) Osteoporos Int , vol.16 , pp. 861-870
    • Oleksik, A.M.1    Ewing, S.2    Shen, W.3    van Schoor, N.M.4    Lips, P.5
  • 12
    • 59649116770 scopus 로고    scopus 로고
    • Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women
    • Bliuc D., Nguyen N.D., Milch V.E., Nguyen T.V., Eisman J.A., Center J.R. Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women. JAMA 2009, 301:513-521.
    • (2009) JAMA , vol.301 , pp. 513-521
    • Bliuc, D.1    Nguyen, N.D.2    Milch, V.E.3    Nguyen, T.V.4    Eisman, J.A.5    Center, J.R.6
  • 13
    • 0034022117 scopus 로고    scopus 로고
    • Prevalent vertebral deformities predict mortality and hospitalization in older women with low bone mass
    • Ensrud K.E., Thompson D.E., Cauley J.A., Nevitt M.C., Kado D.M., Hochberg M.C., et al. Prevalent vertebral deformities predict mortality and hospitalization in older women with low bone mass. J Am Geriatr Soc 2000, 48:241-249.
    • (2000) J Am Geriatr Soc , vol.48 , pp. 241-249
    • Ensrud, K.E.1    Thompson, D.E.2    Cauley, J.A.3    Nevitt, M.C.4    Kado, D.M.5    Hochberg, M.C.6
  • 14
    • 34247194211 scopus 로고    scopus 로고
    • Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025
    • Burge R., Dawson-Hughes B., Solomon D.H., Wong J.B., King A., Tosteson A. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res 2007, 22:465-475.
    • (2007) J Bone Miner Res , vol.22 , pp. 465-475
    • Burge, R.1    Dawson-Hughes, B.2    Solomon, D.H.3    Wong, J.B.4    King, A.5    Tosteson, A.6
  • 17
    • 0032951747 scopus 로고    scopus 로고
    • Prevalent vertebral deformities predict hip fractures and new vertebral deformities but not wrist fractures
    • Study of Osteoporotic Fractures Research Group
    • Black D.M., Arden N.K., Palermo L., Pearson J., Cummings S.R. Prevalent vertebral deformities predict hip fractures and new vertebral deformities but not wrist fractures. J Bone Miner Res 1999, 14:821-828. Study of Osteoporotic Fractures Research Group.
    • (1999) J Bone Miner Res , vol.14 , pp. 821-828
    • Black, D.M.1    Arden, N.K.2    Palermo, L.3    Pearson, J.4    Cummings, S.R.5
  • 19
    • 84863375739 scopus 로고    scopus 로고
    • Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study
    • Liu C.T., Karasik D., Zhou Y., Hsu Y.H., Genant H.K., Broe K.E., et al. Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study. J Bone Miner Res 2011, 27:954-958.
    • (2011) J Bone Miner Res , vol.27 , pp. 954-958
    • Liu, C.T.1    Karasik, D.2    Zhou, Y.3    Hsu, Y.H.4    Genant, H.K.5    Broe, K.E.6
  • 20
    • 8444247855 scopus 로고    scopus 로고
    • A family history of fracture and fracture risk: a meta-analysis
    • Kanis J.A., Johansson H., Oden A., Johnell O., De Laet C., Eisman J.A., et al. A family history of fracture and fracture risk: a meta-analysis. Bone 2004, 35:1029-1037.
    • (2004) Bone , vol.35 , pp. 1029-1037
    • Kanis, J.A.1    Johansson, H.2    Oden, A.3    Johnell, O.4    De Laet, C.5    Eisman, J.A.6
  • 21
    • 77954407332 scopus 로고    scopus 로고
    • Genomewide association studies and assessment of the risk of disease
    • Manolio T.A. Genomewide association studies and assessment of the risk of disease. N Engl J Med 2010, 363:166-176.
    • (2010) N Engl J Med , vol.363 , pp. 166-176
    • Manolio, T.A.1
  • 22
    • 84860331458 scopus 로고    scopus 로고
    • Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
    • Estrada K., Styrkarsdottir U., Evangelou E., Hsu Y.H., Duncan E.L., Ntzani E.E., et al. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet 2012, 44:491-501.
    • (2012) Nat Genet , vol.44 , pp. 491-501
    • Estrada, K.1    Styrkarsdottir, U.2    Evangelou, E.3    Hsu, Y.H.4    Duncan, E.L.5    Ntzani, E.E.6
  • 23
    • 70350646912 scopus 로고    scopus 로고
    • Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies
    • Rivadeneira F., Styrkarsdottir U., Estrada K., Halldorsson B.V., Hsu Y.H., Richards J.B., et al. Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet 2009, 41:1199-1206.
    • (2009) Nat Genet , vol.41 , pp. 1199-1206
    • Rivadeneira, F.1    Styrkarsdottir, U.2    Estrada, K.3    Halldorsson, B.V.4    Hsu, Y.H.5    Richards, J.B.6
  • 24
    • 84863887333 scopus 로고    scopus 로고
    • Genetics of osteoporosis from genome-wide association studies: advances and challenges
    • Richards J.B., Zheng H.F., Spector T.D. Genetics of osteoporosis from genome-wide association studies: advances and challenges. Nat Rev Genet 2012, 13:576-588.
    • (2012) Nat Rev Genet , vol.13 , pp. 576-588
    • Richards, J.B.1    Zheng, H.F.2    Spector, T.D.3
  • 26
    • 41949128499 scopus 로고    scopus 로고
    • Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study
    • Langdahl B.L., Uitterlinden A.G., Ralston S.H., Trikalinos T.A., Balcells S., Brandi M.L., et al. Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study. Bone 2008, 42:969-981.
    • (2008) Bone , vol.42 , pp. 969-981
    • Langdahl, B.L.1    Uitterlinden, A.G.2    Ralston, S.H.3    Trikalinos, T.A.4    Balcells, S.5    Brandi, M.L.6
  • 27
    • 33646248070 scopus 로고    scopus 로고
    • Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study
    • Ralston S.H., Uitterlinden A.G., Brandi M.L., Balcells S., Langdahl B.L., Lips P., et al. Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study. PLoS Med 2006, 3:e90.
    • (2006) PLoS Med , vol.3
    • Ralston, S.H.1    Uitterlinden, A.G.2    Brandi, M.L.3    Balcells, S.4    Langdahl, B.L.5    Lips, P.6
  • 28
    • 79955578829 scopus 로고    scopus 로고
    • Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk
    • Duncan E.L., Danoy P., Kemp J.P., Leo P.J., McCloskey E., Nicholson G.C., et al. Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. PLoS Genet 2011, 7:e1001372.
    • (2011) PLoS Genet , vol.7
    • Duncan, E.L.1    Danoy, P.2    Kemp, J.P.3    Leo, P.J.4    McCloskey, E.5    Nicholson, G.C.6
  • 29
    • 41849149688 scopus 로고    scopus 로고
    • Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes
    • Sims A.M., Shephard N., Carter K., Doan T., Dowling A., Duncan E.L., et al. Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes. J Bone Miner Res 2008, 23:499-506.
    • (2008) J Bone Miner Res , vol.23 , pp. 499-506
    • Sims, A.M.1    Shephard, N.2    Carter, K.3    Doan, T.4    Dowling, A.5    Duncan, E.L.6
  • 32
    • 33845922409 scopus 로고    scopus 로고
    • Clodronate reduces the incidence of fractures in community-dwelling elderly women unselected for osteoporosis: results of a double-blind, placebo-controlled randomized study
    • McCloskey E.V., Beneton M., Charlesworth D., Kayan K., deTakats D., Dey A., et al. Clodronate reduces the incidence of fractures in community-dwelling elderly women unselected for osteoporosis: results of a double-blind, placebo-controlled randomized study. J Bone Miner Res 2007, 22:135-141.
    • (2007) J Bone Miner Res , vol.22 , pp. 135-141
    • McCloskey, E.V.1    Beneton, M.2    Charlesworth, D.3    Kayan, K.4    deTakats, D.5    Dey, A.6
  • 33
    • 77953869175 scopus 로고    scopus 로고
    • Genotypes and haplotypes of the estrogen receptor genes, but not the retinoblastoma-interacting zinc finger protein 1 gene, are associated with osteoporosis
    • Harslof T., Husted L.B., Carstens M., Stenkjaer L., Langdahl B.L. Genotypes and haplotypes of the estrogen receptor genes, but not the retinoblastoma-interacting zinc finger protein 1 gene, are associated with osteoporosis. Calcif Tissue Int 2010, 87:25-35.
    • (2010) Calcif Tissue Int , vol.87 , pp. 25-35
    • Harslof, T.1    Husted, L.B.2    Carstens, M.3    Stenkjaer, L.4    Langdahl, B.L.5
  • 37
    • 33846945766 scopus 로고    scopus 로고
    • Identification of an aromatase haplotype that is associated with gene expression and postmenopausal osteoporosis
    • Riancho J.A., Valero C., Naranjo A., Morales D.J., Sanudo C., Zarrabeitia M.T. Identification of an aromatase haplotype that is associated with gene expression and postmenopausal osteoporosis. J Clin Endocrinol Metab 2007, 92:660-665.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 660-665
    • Riancho, J.A.1    Valero, C.2    Naranjo, A.3    Morales, D.J.4    Sanudo, C.5    Zarrabeitia, M.T.6
  • 38
    • 33847704966 scopus 로고    scopus 로고
    • Adiposity, estradiol, and genetic variants of steroid-metabolizing enzymes as determinants of bone mineral density
    • Zarrabeitia M.T., Hernandez J.L., Valero C., Zarrabeitia A., Amado J.A., Gonzalez-Macias J., et al. Adiposity, estradiol, and genetic variants of steroid-metabolizing enzymes as determinants of bone mineral density. Eur J Endocrinol 2007, 156:117-122.
    • (2007) Eur J Endocrinol , vol.156 , pp. 117-122
    • Zarrabeitia, M.T.1    Hernandez, J.L.2    Valero, C.3    Zarrabeitia, A.4    Amado, J.A.5    Gonzalez-Macias, J.6
  • 39
    • 33646131205 scopus 로고    scopus 로고
    • Effects of calcium supplementation on clinical fracture and bone structure: results of a 5-year, double-blind, placebo-controlled trial in elderly women
    • Prince R.L., Devine A., Dhaliwal S.S., Dick I.M. Effects of calcium supplementation on clinical fracture and bone structure: results of a 5-year, double-blind, placebo-controlled trial in elderly women. Arch Intern Med 2006, 166:869-875.
    • (2006) Arch Intern Med , vol.166 , pp. 869-875
    • Prince, R.L.1    Devine, A.2    Dhaliwal, S.S.3    Dick, I.M.4
  • 42
    • 0034520197 scopus 로고    scopus 로고
    • Estimation of the prevalence of low bone density in Canadian women and men using a population-specific DXA reference standard: the Canadian Multicentre Osteoporosis Study (CaMos)
    • Tenenhouse A., Joseph L., Kreiger N., Poliquin S., Murray T.M., Blondeau L., et al. Estimation of the prevalence of low bone density in Canadian women and men using a population-specific DXA reference standard: the Canadian Multicentre Osteoporosis Study (CaMos). Osteoporos Int 2000, 11:897-904.
    • (2000) Osteoporos Int , vol.11 , pp. 897-904
    • Tenenhouse, A.1    Joseph, L.2    Kreiger, N.3    Poliquin, S.4    Murray, T.M.5    Blondeau, L.6
  • 43
    • 0033038617 scopus 로고    scopus 로고
    • The Danish Osteoporosis Prevention Study (DOPS): project design and inclusion of 2000 normal perimenopausal women
    • Mosekilde L., Hermann A.P., Beck-Nielsen H., Charles P., Nielsen S.P., Sorensen O.H. The Danish Osteoporosis Prevention Study (DOPS): project design and inclusion of 2000 normal perimenopausal women. Maturitas 1999, 31:207-219.
    • (1999) Maturitas , vol.31 , pp. 207-219
    • Mosekilde, L.1    Hermann, A.P.2    Beck-Nielsen, H.3    Charles, P.4    Nielsen, S.P.5    Sorensen, O.H.6
  • 44
    • 0034002439 scopus 로고    scopus 로고
    • Validity of self-report of fractures: results from a prospective study in men and women across Europe. EPOS Study Group. European Prospective Osteoporosis Study Group
    • Ismail A.A., O'Neill T.W., Cockerill W., Finn J.D., Cannata J.B., Hoszowski K., et al. Validity of self-report of fractures: results from a prospective study in men and women across Europe. EPOS Study Group. European Prospective Osteoporosis Study Group. Osteoporos Int 2000, 11:248-254.
    • (2000) Osteoporos Int , vol.11 , pp. 248-254
    • Ismail, A.A.1    O'Neill, T.W.2    Cockerill, W.3    Finn, J.D.4    Cannata, J.B.5    Hoszowski, K.6
  • 45
    • 0030001379 scopus 로고    scopus 로고
    • The prevalence of vertebral deformity in European men and women: the European Vertebral Osteoporosis Study
    • O'Neill T.W., Felsenberg D., Varlow J., Cooper C., Kanis J.A., Silman A.J. The prevalence of vertebral deformity in European men and women: the European Vertebral Osteoporosis Study. J Bone Miner Res 1996, 11:1010-1018.
    • (1996) J Bone Miner Res , vol.11 , pp. 1010-1018
    • O'Neill, T.W.1    Felsenberg, D.2    Varlow, J.3    Cooper, C.4    Kanis, J.A.5    Silman, A.J.6
  • 47
    • 0018612858 scopus 로고
    • An investigation of coronary heart disease in families. The Framingham offspring study
    • Kannel W.B., Feinleib M., McNamara P.M., Garrison R.J., Castelli W.P. An investigation of coronary heart disease in families. The Framingham offspring study. Am J Epidemiol 1979, 110:281-290.
    • (1979) Am J Epidemiol , vol.110 , pp. 281-290
    • Kannel, W.B.1    Feinleib, M.2    McNamara, P.M.3    Garrison, R.J.4    Castelli, W.P.5
  • 48
    • 34247579476 scopus 로고    scopus 로고
    • The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination
    • Splansky G.L., Corey D., Yang Q., Atwood L.D., Cupples L.A., Benjamin E.J., et al. The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination. Am J Epidemiol 2007, 165:1328-1335.
    • (2007) Am J Epidemiol , vol.165 , pp. 1328-1335
    • Splansky, G.L.1    Corey, D.2    Yang, Q.3    Atwood, L.D.4    Cupples, L.A.5    Benjamin, E.J.6
  • 49
    • 38449103748 scopus 로고    scopus 로고
    • Association of FLT3 polymorphisms with low BMD and risk of osteoporotic fracture in postmenopausal women
    • Koh J.M., Oh B., Lee J.Y., Lee J.K., Kimm K., Park B.L., et al. Association of FLT3 polymorphisms with low BMD and risk of osteoporotic fracture in postmenopausal women. J Bone Miner Res 2007, 22:1752-1758.
    • (2007) J Bone Miner Res , vol.22 , pp. 1752-1758
    • Koh, J.M.1    Oh, B.2    Lee, J.Y.3    Lee, J.K.4    Kimm, K.5    Park, B.L.6
  • 50
    • 0036131102 scopus 로고    scopus 로고
    • Attrition in the Longitudinal Aging Study Amsterdam. The effect of differential inclusion in side studies
    • Deeg D.J., van Tilburg T., Smit J.H., de Leeuw E.D. Attrition in the Longitudinal Aging Study Amsterdam. The effect of differential inclusion in side studies. J Clin Epidemiol 2002, 55:319-328.
    • (2002) J Clin Epidemiol , vol.55 , pp. 319-328
    • Deeg, D.J.1    van Tilburg, T.2    Smit, J.H.3    de Leeuw, E.D.4
  • 51
    • 33645333405 scopus 로고    scopus 로고
    • Free testosterone is an independent predictor of BMD and prevalent fractures in elderly men: MrOS Sweden
    • Mellstrom D., Johnell O., Ljunggren O., Eriksson A.L., Lorentzon M., Mallmin H., et al. Free testosterone is an independent predictor of BMD and prevalent fractures in elderly men: MrOS Sweden. J Bone Miner Res 2006, 21:529-535.
    • (2006) J Bone Miner Res , vol.21 , pp. 529-535
    • Mellstrom, D.1    Johnell, O.2    Ljunggren, O.3    Eriksson, A.L.4    Lorentzon, M.5    Mallmin, H.6
  • 52
    • 33847639253 scopus 로고    scopus 로고
    • Links between cardiovascular disease and osteoporosis in postmenopausal women: serum lipids or atherosclerosis per se?
    • Bagger Y.Z., Rasmussen H.B., Alexandersen P., Werge T., Christiansen C., Tanko L.B. Links between cardiovascular disease and osteoporosis in postmenopausal women: serum lipids or atherosclerosis per se?. Osteoporos Int 2007, 18:505-512.
    • (2007) Osteoporos Int , vol.18 , pp. 505-512
    • Bagger, Y.Z.1    Rasmussen, H.B.2    Alexandersen, P.3    Werge, T.4    Christiansen, C.5    Tanko, L.B.6
  • 53
    • 0027252910 scopus 로고
    • The assessment of vertebral deformity: a method for use in population studies and clinical trials
    • McCloskey E.V., Spector T.D., Eyres K.S., Fern E.D., O'Rourke N., Vasikaran S., et al. The assessment of vertebral deformity: a method for use in population studies and clinical trials. Osteoporos Int 1993, 3:138-147.
    • (1993) Osteoporos Int , vol.3 , pp. 138-147
    • McCloskey, E.V.1    Spector, T.D.2    Eyres, K.S.3    Fern, E.D.4    O'Rourke, N.5    Vasikaran, S.6
  • 54
    • 0027219544 scopus 로고
    • Vertebral fracture assessment using a semiquantitative technique
    • Genant H.K., Wu C.Y., van Kuijk C., Nevitt M.C. Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 1993, 8:1137-1148.
    • (1993) J Bone Miner Res , vol.8 , pp. 1137-1148
    • Genant, H.K.1    Wu, C.Y.2    van Kuijk, C.3    Nevitt, M.C.4
  • 55
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • The International HapMap Project. Nature 2003, 426:789-796.
    • (2003) Nature , vol.426 , pp. 789-796
  • 58
    • 78649508578 scopus 로고    scopus 로고
    • MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes
    • Li Y., Willer C.J., Ding J., Scheet P., Abecasis G.R. MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet Epidemiol 2010, 34:816-834.
    • (2010) Genet Epidemiol , vol.34 , pp. 816-834
    • Li, Y.1    Willer, C.J.2    Ding, J.3    Scheet, P.4    Abecasis, G.R.5
  • 59
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price A.L., Patterson N.J., Plenge R.M., Weinblatt M.E., Shadick N.A., Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006, 38:904-909.
    • (2006) Nat Genet , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5    Reich, D.6
  • 60
    • 70349999413 scopus 로고    scopus 로고
    • GRIMP: a web- and grid-based tool for high-speed analysis of large-scale genome-wide association using imputed data
    • Estrada K., Abuseiris A., Grosveld F.G., Uitterlinden A.G., Knoch T.A., Rivadeneira F. GRIMP: a web- and grid-based tool for high-speed analysis of large-scale genome-wide association using imputed data. Bioinformatics 2009, 25:2750-2752.
    • (2009) Bioinformatics , vol.25 , pp. 2750-2752
    • Estrada, K.1    Abuseiris, A.2    Grosveld, F.G.3    Uitterlinden, A.G.4    Knoch, T.A.5    Rivadeneira, F.6
  • 61
    • 77955894071 scopus 로고    scopus 로고
    • METAL: fast and efficient meta-analysis of genomewide association scans
    • Willer C.J., Li Y., Abecasis G.R. METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics 2010, 26:2190-2191.
    • (2010) Bioinformatics , vol.26 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2    Abecasis, G.R.3
  • 62
    • 79955860273 scopus 로고    scopus 로고
    • Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
    • Han B., Eskin E. Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am J Hum Genet 2011, 88:586-598.
    • (2011) Am J Hum Genet , vol.88 , pp. 586-598
    • Han, B.1    Eskin, E.2
  • 63
    • 66449113643 scopus 로고    scopus 로고
    • Genomic and genic deletions of the FOX gene cluster on 16q24.1 and inactivating mutations of FOXF1 cause alveolar capillary dysplasia and other malformations
    • Stankiewicz P., Sen P., Bhatt S.S., Storer M., Xia Z., Bejjani B.A., et al. Genomic and genic deletions of the FOX gene cluster on 16q24.1 and inactivating mutations of FOXF1 cause alveolar capillary dysplasia and other malformations. Am J Hum Genet 2009, 84:780-791.
    • (2009) Am J Hum Genet , vol.84 , pp. 780-791
    • Stankiewicz, P.1    Sen, P.2    Bhatt, S.S.3    Storer, M.4    Xia, Z.5    Bejjani, B.A.6
  • 64
    • 0034803019 scopus 로고    scopus 로고
    • Bone morphogenetic protein regulation of forkhead/winged helix transcription factor Foxc2 (Mfh1) in a murine mesodermal cell line C1 and in skeletal precursor cells
    • Nifuji A., Miura N., Kato N., Kellermann O., Noda M. Bone morphogenetic protein regulation of forkhead/winged helix transcription factor Foxc2 (Mfh1) in a murine mesodermal cell line C1 and in skeletal precursor cells. J Bone Miner Res 2001, 16:1765-1771.
    • (2001) J Bone Miner Res , vol.16 , pp. 1765-1771
    • Nifuji, A.1    Miura, N.2    Kato, N.3    Kellermann, O.4    Noda, M.5
  • 66
    • 0030991153 scopus 로고    scopus 로고
    • The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo
    • Winnier G.E., Hargett L., Hogan B.L. The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo. Genes Dev 1997, 11:926-940.
    • (1997) Genes Dev , vol.11 , pp. 926-940
    • Winnier, G.E.1    Hargett, L.2    Hogan, B.L.3
  • 67
  • 68
    • 33845770756 scopus 로고    scopus 로고
    • The evolution of epidemiologic research: from cottage industry to "big" science
    • Hoover R.N. The evolution of epidemiologic research: from cottage industry to "big" science. Epidemiology 2007, 18:13-17.
    • (2007) Epidemiology , vol.18 , pp. 13-17
    • Hoover, R.N.1
  • 69
    • 84863338087 scopus 로고    scopus 로고
    • What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations
    • Panagiotou O.A., Ioannidis J.P. What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations. Int J Epidemiol 2012, 41:273-286.
    • (2012) Int J Epidemiol , vol.41 , pp. 273-286
    • Panagiotou, O.A.1    Ioannidis, J.P.2
  • 70
    • 50549104256 scopus 로고    scopus 로고
    • Why most discovered true associations are inflated
    • Ioannidis J.P. Why most discovered true associations are inflated. Epidemiology 2008, 19:640-648.
    • (2008) Epidemiology , vol.19 , pp. 640-648
    • Ioannidis, J.P.1
  • 71
    • 77955144299 scopus 로고    scopus 로고
    • Replication in genome-wide association studies
    • Kraft P., Zeggini E., Ioannidis J.P. Replication in genome-wide association studies. Stat Sci 2009, 24:561-573.
    • (2009) Stat Sci , vol.24 , pp. 561-573
    • Kraft, P.1    Zeggini, E.2    Ioannidis, J.P.3
  • 72
    • 75649147432 scopus 로고    scopus 로고
    • Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases
    • Zhong H., Prentice R.L. Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases. Genet Epidemiol 2010, 34:78-91.
    • (2010) Genet Epidemiol , vol.34 , pp. 78-91
    • Zhong, H.1    Prentice, R.L.2
  • 73
    • 0037312921 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    • Lohmueller K.E., Pearce C.L., Pike M., Lander E.S., Hirschhorn J.N. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 2003, 33:177-182.
    • (2003) Nat Genet , vol.33 , pp. 177-182
    • Lohmueller, K.E.1    Pearce, C.L.2    Pike, M.3    Lander, E.S.4    Hirschhorn, J.N.5
  • 74
    • 33645767434 scopus 로고    scopus 로고
    • An evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population
    • Montpetit A., Nelis M., Laflamme P., Magi R., Ke X., Remm M., et al. An evaluation of the performance of tag SNPs derived from HapMap in a Caucasian population. PLoS Genet 2006, 2:e27.
    • (2006) PLoS Genet , vol.2
    • Montpetit, A.1    Nelis, M.2    Laflamme, P.3    Magi, R.4    Ke, X.5    Remm, M.6
  • 75
    • 78651410150 scopus 로고    scopus 로고
    • Caution in generalizing known genetic risk markers for breast cancer across all ethnic/racial populations
    • Chen F., Stram D.O., Le Marchand L., Monroe K.R., Kolonel L.N., Henderson B.E., et al. Caution in generalizing known genetic risk markers for breast cancer across all ethnic/racial populations. Eur J Hum Genet 2011, 19:243-245.
    • (2011) Eur J Hum Genet , vol.19 , pp. 243-245
    • Chen, F.1    Stram, D.O.2    Le Marchand, L.3    Monroe, K.R.4    Kolonel, L.N.5    Henderson, B.E.6
  • 76
    • 78651443365 scopus 로고    scopus 로고
    • Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations
    • He J., Wilkens L.R., Stram D.O., Kolonel L.N., Henderson B.E., Wu A.H., et al. Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations. Cancer Epidemiol Biomarkers Prev 2011, 20:70-81.
    • (2011) Cancer Epidemiol Biomarkers Prev , vol.20 , pp. 70-81
    • He, J.1    Wilkens, L.R.2    Stram, D.O.3    Kolonel, L.N.4    Henderson, B.E.5    Wu, A.H.6
  • 77
    • 79955638028 scopus 로고    scopus 로고
    • Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia
    • Sim X., Ong R.T., Suo C., Tay W.T., Liu J., Ng D.P., et al. Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. PLoS Genet 2011, 7:e1001363.
    • (2011) PLoS Genet , vol.7
    • Sim, X.1    Ong, R.T.2    Suo, C.3    Tay, W.T.4    Liu, J.5    Ng, D.P.6
  • 78
    • 70349860293 scopus 로고    scopus 로고
    • Ranking of genome-wide association scan signals by different measures
    • Stromberg U., Bjork J., Vineis P., Broberg K., Zeggini E. Ranking of genome-wide association scan signals by different measures. Int J Epidemiol 2009, 38:1364-1373.
    • (2009) Int J Epidemiol , vol.38 , pp. 1364-1373
    • Stromberg, U.1    Bjork, J.2    Vineis, P.3    Broberg, K.4    Zeggini, E.5
  • 79
    • 84878164957 scopus 로고    scopus 로고
    • Review of radiological scoring methods of osteoporotic vertebral fractures for clinical and research settings
    • Oei L., Rivadeneira F., Ly F., Breda S.J., Zillikens M.C., Hofman A., et al. Review of radiological scoring methods of osteoporotic vertebral fractures for clinical and research settings. Eur Radiol 2013, 23(2):476-486.
    • (2013) Eur Radiol , vol.23 , Issue.2 , pp. 476-486
    • Oei, L.1    Rivadeneira, F.2    Ly, F.3    Breda, S.J.4    Zillikens, M.C.5    Hofman, A.6
  • 80
    • 78651481020 scopus 로고    scopus 로고
    • Severity of vertebral fracture and risk of hip fracture: a nested case-control study
    • Puisto V., Heliovaara M., Impivaara O., Jalanko T., Kroger H., Knekt P., et al. Severity of vertebral fracture and risk of hip fracture: a nested case-control study. Osteoporos Int 2011, 22:63-68.
    • (2011) Osteoporos Int , vol.22 , pp. 63-68
    • Puisto, V.1    Heliovaara, M.2    Impivaara, O.3    Jalanko, T.4    Kroger, H.5    Knekt, P.6
  • 81
    • 8644238812 scopus 로고    scopus 로고
    • Comparison of methods for the visual identification of prevalent vertebral fracture in osteoporosis
    • Jiang G., Eastell R., Barrington N.A., Ferrar L. Comparison of methods for the visual identification of prevalent vertebral fracture in osteoporosis. Osteoporos Int 2004, 15:887-896.
    • (2004) Osteoporos Int , vol.15 , pp. 887-896
    • Jiang, G.1    Eastell, R.2    Barrington, N.A.3    Ferrar, L.4
  • 82
    • 79951853292 scopus 로고    scopus 로고
    • Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium
    • Kerkhof H.J., Meulenbelt I., Akune T., Arden N.K., Aromaa A., Bierma-Zeinstra S.M., et al. Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: the TREAT-OA consortium. Osteoarthritis Cartilage 2011, 19:254-264.
    • (2011) Osteoarthritis Cartilage , vol.19 , pp. 254-264
    • Kerkhof, H.J.1    Meulenbelt, I.2    Akune, T.3    Arden, N.K.4    Aromaa, A.5    Bierma-Zeinstra, S.M.6
  • 83
    • 10744229381 scopus 로고    scopus 로고
    • Determinants of the size of incident vertebral deformities in European men and women in the sixth to ninth decades of age: the European Prospective Osteoporosis Study (EPOS)
    • Reeve J., Lunt M., Felsenberg D., Silman A.J., Scheidt-Nave C., Poor G., et al. Determinants of the size of incident vertebral deformities in European men and women in the sixth to ninth decades of age: the European Prospective Osteoporosis Study (EPOS). J Bone Miner Res 2003, 18:1664-1673.
    • (2003) J Bone Miner Res , vol.18 , pp. 1664-1673
    • Reeve, J.1    Lunt, M.2    Felsenberg, D.3    Silman, A.J.4    Scheidt-Nave, C.5    Poor, G.6
  • 84
    • 0036128572 scopus 로고    scopus 로고
    • Incidence of vertebral fracture in Europe: results from the European Prospective Osteoporosis Study (EPOS)
    • Felsenberg D., Silman A.J., Lunt M., Armbrecht G., Ismail A.A., Finn J.D., et al. Incidence of vertebral fracture in Europe: results from the European Prospective Osteoporosis Study (EPOS). J Bone Miner Res 2002, 17:716-724.
    • (2002) J Bone Miner Res , vol.17 , pp. 716-724
    • Felsenberg, D.1    Silman, A.J.2    Lunt, M.3    Armbrecht, G.4    Ismail, A.A.5    Finn, J.D.6
  • 85
    • 0036820823 scopus 로고    scopus 로고
    • Defining incident vertebral deformities in population studies: a comparison of morphometric criteria
    • Lunt M., Ismail A.A., Felsenberg D., Cooper C., Kanis J.A., Reeve J., et al. Defining incident vertebral deformities in population studies: a comparison of morphometric criteria. Osteoporos Int 2002, 13:809-815.
    • (2002) Osteoporos Int , vol.13 , pp. 809-815
    • Lunt, M.1    Ismail, A.A.2    Felsenberg, D.3    Cooper, C.4    Kanis, J.A.5    Reeve, J.6
  • 86
    • 0035658157 scopus 로고    scopus 로고
    • A statistical method to minimize magnification errors in serial vertebral radiographs
    • Lunt M., Gowin W., Johnell, Armbrecht G., Felsenberg D. A statistical method to minimize magnification errors in serial vertebral radiographs. Osteoporos Int 2001, 12:909-13.
    • (2001) Osteoporos Int , vol.12 , pp. 909-913
    • Lunt, M.1    Gowin, W.2    Johnell3    Armbrecht, G.4    Felsenberg, D.5


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