Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women

JAMA

Volumn 301, Issue 5, 2009, Pages 513-521

  Bliuc, Dana ^a   Nguyen, Nguyen D ^a   Milch, Vivienne E ^a   Nguyen, Tuan V ^a   Eisman, John A ^a   Center, Jacqueline R ^a,b  

^a ST VINCENT S HOSPITAL   (Australia)

^b GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; AUSTRALIA; BONE DENSITY; FEMALE; FRAGILITY FRACTURE; HIP FRACTURE; HUMAN; INJURY; MAJOR CLINICAL STUDY; MALE; MORTALITY; MUSCLE WEAKNESS; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; SMOKING; VERTEBRA FRACTURE; FRACTURE; INCIDENCE; KAPLAN MEIER METHOD; LONGITUDINAL STUDY; MIDDLE AGED; OSTEOPOROSIS; RISK FACTOR;

AGED; AGED, 80 AND OVER; BONE DENSITY; FEMALE; FRACTURES, BONE; HUMANS; INCIDENCE; KAPLAN-MEIERS ESTIMATE; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; MORTALITY; NEW SOUTH WALES; OSTEOPOROSIS; RISK FACTORS;

EID: 59649116770     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2009.50     Document Type: Article

References (35)

1. The burden of brittle bones: costing osteoporosis in Australia. Prepared for Osteoporosis Australia by Access Economics Pty Ltd, Canberra, 2001. http://www.arthritiswa.org.au/Resources/Osteoporosis%20Reports/Brittle%20Bones. pdf. Accessed Janu-ary 2, 2009.
2. Cummings SR, Melton LJ. Epidemiology and outcomes of osteoporotic fractures. Lancet. 2002;359(9319):1761-1767.
3. Cooper C. The crippling consequences of fractures and their impact on quality of life. Am J Med. 1997;103(2A):12S-17S.
4. Randell AG, Nguyen TV, Bhalerao N, Silverman SL, Sambrook PN, Eisman JA. Deterioration in quality of life following hip fracture: a prospective study. Os-teoporos Int. 2000;11(5):460-466.
5. Center JR, Nguyen TV, Schneider P, Sambrook PN, Eisman JA. Mortality after all major types of osteo-porotic fracture in men and women: an observational study. Lancet. 1999;353(9156):878-882.
6. Cauley JA, Thompson DE, Ensrud KC, Scott JC, Black D. Risk of mortality following clinical fractures. Os-teoporos Int. 2000;11(7):556-561.
7. Browner WS, Pressman AR, Nevitt MC, Cummings SR. Mortality following fractures in older women: the study of osteoporotic fractures. Arch Intern Med. 1996;156(14):1521-1525.
8. Johnell O, Kanis JA, Oden A, et al. Mortality after osteoporotic fractures. Osteoporos Int. 2004;15 (1):38-42.
9. Vestergaard P, Rejnmark L, Mosekilde L. Increased mortality in patients with a hip fracture: effect of pre-morbid conditions and post-fracture complications. Osteoporos Int. 2007;18(12):1583-1593.
10. Hasserius R, Karlsson MK, Jonsson B, Redlund-Johnell I, Johnell O. Long-term morbidity and mortality after a clinically diagnosed vertebral fracture in the elderly: a 12-and 22-yearfollow-up of 257 patients. Calcif Tissue Int. 2005;76(4):235-242.
11. Center JR, Bliuc D, Nguyen TV, Eisman JA. Risk of subsequent fracture after low-trauma fracture in men and women. JAMA. 2007;297(4):387-394.
12. Tosteson AN, Gottlieb DJ, Radley DC, Fisher ES, Melton LJ III. Excess mortality following hip fracture: the role of underlying health status. Osteoporos Int. 2007;18(11):1463-1472.
13. SimonsLA, McCallum J, SimonsJ, etal. TheDubbo study: an Australian prospective community study of the health of elderly. Aust N Z J Med. 1990;20 (6):783-789.
14. Jones G, Nguyen T, Sambrook PN, Kelly PJ, Gilbert C, Eisman JA. Symptomatic fracture incidence in elderly men and women: the Dubbo Osteoporosis Epi-demiology Study (DOES). Osteoporos Int. 1994;4(5):277-282.
15. Woodward M. Formulae for sample size, power and minimum detectable relative risk inmedical studies. Statistician. 1992;41:185-196.
16. Base SAS: 9.1.3 Procedures Guide. 2nd ed. Cary, NC: SAS Publishing; 2006.
17. Haentjens P, Johnell O, Kanis JA, et al; Network on Male Osteoporosis in Europe (NEMO). Evidence from data searches and life-table analyses for gender-related differences in absolute risk of hip fracture after Colles' or spine fracture: Colles' fracture as an early and sensitive marker of skeletal fragility in white men. J Bone Miner Res. 2004;19(12):1933-1944.
18. Pongchaiyakul C, Nguyen ND, Jones G, Center JR, Eisman JA, Nguyen TV. Asymptomatic vertebral deformity as a major risk factor for subsequent fractures and mortality: a long-term prospective study. J Bone Miner Res. 2005;20(8):1349-1355.
19. Forsen L, Sogaard AJ, Meyer HE, Edna T, Kopjar B. Survival after hip fracture: short- and long-term excess mortality according to age and gender. Osteoporos Int. 1999;10(1):73-78.
20. Empana JP, Dargent-Molina P, Breart G; EPI-DOS Group. Effect of hip fracture on mortality in el-derly women: the EPIDOS prospective study. J Am Geriatr Soc. 2004;52(5):685-690.
21. Kado DM, Browner WS, Palermo L, Nevitt MC, Genant HK, Cummings SR; Study of Osteoporotic Fractures Research Group. Vertebral fractures and mortality in older women: a prospective study. Arch Intern Med. 1999;159(11):1215- 1220.
22. Kanis JA, Oden A, Johnell O, De Laet C, Jonsson B, Oglesby AK. The components of excess mortality after hip fracture. Bone. 2003;32(5):468-473.
23. Kanis JA, Oden A, Johnell O, De Laet C, Jonsson B. Excess mortality after hospitalisation for vertebral fracture. Osteoporos Int. 2004;15(2):108-112.
24. Trone DW, Kritz-Silverstein D, von Muhlen DG, Wingard DL, Barrett-Connor E. Is radiographic vertebral fracture a risk factor for mortality? Am J Epidemiol. 2007;166(10):1191-1197.
25. Farahmand BY, Michaelsson K, Ahlbom A, Ljunghall S, Baron JA; Swedish Hip Fracture Study Group. Survival after hip fracture. Osteoporos Int. 2005;16(12):1583-1590.
26. Karagiannis A, Papakitsou E, Dretakis K, et al. Mortality rates of patients with a hip fracture in a southwestern district of Greece: ten-yearfollow-up with reference to the type of fracture. Calcif Tissue Int. 2006;78(2):72-77.
27. Trombetti A, Herrmann F, Hoffmeyer P, Schurch MA, Bonjour JP, Rizzoli R. Survival and potential years oflife lost after hip fracture in men and age-matched women. Osteoporos Int. 2002;13(9):731-737.
28. Klotzbuecher CM, Ross PD, Landsman PB, Abbott TA III, Berger M. Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res. 2000;15(4):721-739.
29. Kado DM, DuongT, Stone KL, et al. Incidentver-tebral fractures and mortality in older women: a prospective study. Osteoporos Int. 2003;14(7):589-594.
30. Ensrud KE, Ewing SK, Taylor BC, et al; for the Study of Osteoporotic Fractures Research Group. Frailty and risk of falls, fracture, and mortality in older women: the study of osteoporotic fractures. J Gerontol A Biol Sci Med Sci. 2007;62(7):744-751.
31. Cawthon PM, Marshall LM, Michael Y, et al; Os-teoporotic Fractures in Men Research Group. Frailty in older men: prevalence, progression, and relationship with mortality. J Am Geriatr Soc. 2007;55(8):1216-1223.
32. Browner WS, Seeley DG, Vogt TM, Cummings SR; Study of Osteoporotic Fractures Research Group. Non-trauma mortality in elderly women with low bone mineral density. Lancet. 1991;338(8763):355-358.
33. Nguyen ND, Center JR, Eisman JA, Nguyen TV. Bone loss, weight loss, and weight fluctuation predict mortality risk in elderly men and women. J Bone Miner Res. 2007;22(8):1147-1154.
34. Ensrud KE, Thompson DE, Cauley JA, et al; Frac-tureIntervention Trial Research Group. Prevalentver-tebral deformities predict mortality and hospitaliza-tion in older women with low bone mass. J Am Geriatr Soc. 2000;48(3):241-249.
35. Lyles KW, Colon-Emeric CS, Magaziner JS, et al; HORIZON Recurrent Fracture Trial. Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med. 2007;357(18):1799-1809.