Neddylation plays an important role in the regulation of murine and human dendritic cell function

Blood

Volumn 122, Issue 12, 2013, Pages 2062-2073

  Mathewson, Nathan ^a,b   Toubai, Tomomi ^a   Kapeles, Steven ^a   Sun, Yaping ^a   Oravecz Wilson, Katherine ^a   Tamaki, Hiroya ^a   Wang, Ying ^a   Hou, Guoqing ^a   Sun, Yi ^b   Reddy, Pavan ^a  

^a UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; BORTEZOMIB; CD40 LIGAND; CD69 ANTIGEN; CD86 ANTIGEN; CULLIN; DEXAMETHASONE; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDOGLYCAN; PEVONEDISTAT; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; PROTEIN; RBX1 PROTEIN; RBX2 PROTEIN; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; ((1S,2S,4R) 4 (4 ((1S) 2,3 DIHYDRO 1H INDEN 1 YLAMINO) 7H PYRROLO(2,3 D)PYRIMIDIN 7 YL) 2 HYDROXYCYCLOPENTYL)METHYL SULPHAMATE; ((1S,2S,4R)-4-(4-((1S)-2,3-DIHYDRO-1H-INDEN-1-YLAMINO)-7H-PYRROLO(2,3-D)PYRIMIDIN-7-YL)-2-HYDROXYCYCLOPENTYL)METHYL SULPHAMATE; AUTACOID; CARRIER PROTEIN; CYCLOPENTANE DERIVATIVE; CYTOKINE; I KAPPA B; NEDD8 PROTEIN, HUMAN; NEDD8 PROTEIN, MOUSE; PYRIMIDINE DERIVATIVE; SAG PROTEIN, MOUSE; UBIQUITIN;

ALLOTRANSPLANTATION; ANIMAL CELL; ARTICLE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CELL LYSATE; CELL VIABILITY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE SILENCING; GRAFT VERSUS HOST REACTION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEDDYLATION; NEGATIVE FEEDBACK; NONHUMAN; OLIGOMERIZATION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; TRANSLATIONAL PROTEIN MODIFICATION; WESTERN BLOTTING; WHOLE BODY RADIATION; ANIMAL; APOPTOSIS; BIOSYNTHESIS; CELL LINE; DRUG EFFECT; DRUG POTENTIATION; ENZYME ACTIVATION; GENETICS; IMMUNOLOGY; METABOLISM; PHENOTYPE; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; APOPTOSIS; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; CARRIER PROTEINS; CELL LINE; CYCLOPENTANES; CYTOKINES; DENDRITIC CELLS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; I-KAPPA B PROTEINS; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHENOTYPE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; PROTEOLYSIS; PYRIMIDINES; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; UBIQUITINS;

EID: 84887568620     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-02-486373     Document Type: Article

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