Factor XI anion-binding sites are required for productive interactions with polyphosphate

Journal of Thrombosis and Haemostasis

Volumn 11, Issue 11, 2013, Pages 2020-2028

  Geng, Y ^a   Verhamme, I M ^a   Smith, S A ^b   Cheng, Q ^a   Sun, M ^a   Sheehan, J P ^c   Morrissey, J H ^b   Gailani, D ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Blood coagulation; Factor XI; Factor XIa; Heparin; PolyPhosphates

Indexed keywords

ANION; ANTITHROMBIN; BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 11A; HEPARIN; POLYANION; POLYPHOSPHATE; RECOMBINANT THROMBIN; BLOOD CLOTTING FACTOR 9; POLYANIONS; POLYMER; RECOMBINANT PROTEIN; THROMBIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY THROMBOSIS; ARTICLE; BINDING SITE; BLOOD CLOTTING; BLOOD CLOTTING TIME; CONTROLLED STUDY; DISEASE ACTIVITY; ENZYME ACTIVE SITE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEINASE INHIBITION; THROMBOSIS; WILD TYPE; ANIMAL; BOVINAE; C57BL MOUSE; CHEMISTRY; METABOLISM;

ANIMALS; ANIONS; ANTITHROMBINS; BINDING SITES; BLOOD COAGULATION; CATTLE; FACTOR IX; FACTOR XI; FACTOR XIA; HEPARIN; HUMANS; MICE; MICE, INBRED C57BL; POLYMERS; POLYPHOSPHATES; RECOMBINANT PROTEINS; THROMBIN; THROMBOSIS;

EID: 84887510096     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12414     Document Type: Article

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