Rubus idaeus L. reverses epithelial-to-mesenchymal transition and suppresses cell invasion and protease activities by targeting ERK1/2 and FAK pathways in human lung cancer cells

Food and Chemical Toxicology

Volumn 62, Issue , 2013, Pages 908-918

  Hsieh, Yih Shou ^a,b   Chu, Shu Chen ^c   Hsu, Li Sung ^a,b   Chen, Kuo Shuen ^a,b   Lai, Ming Tsung ^a,b   Yeh, Chia Heng ^b   Chen, Pei Ni ^a,b  

^a CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

EMT; FAK; Invasion; MMP 2; Rubus idaeus; U PA

Indexed keywords

ALPHA CATENIN; FIBRONECTIN; FOCAL ADHESION KINASE; GELATINASE A; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NERVE CELL ADHESION MOLECULE; PAXILLIN; PLANT EXTRACT; RUBUS IDAEUS EXTRACT; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; UROKINASE; UVOMORULIN; VIMENTIN; WATER; ANTINEOPLASTIC AGENT; CADHERIN; FOCAL ADHESION KINASE 1; MAPK1 PROTEIN, HUMAN; PTK2 PROTEIN, HUMAN; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL INVASION; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG ADENOCARCINOMA; METASTASIS INHIBITION; MOUSE; NONHUMAN; PHYTOCHEMISTRY; PROTEIN EXPRESSION; RASPBERRY; RNA INTERFERENCE; TUMOR XENOGRAFT; UPREGULATION; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; CELL MOTION; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; GENETICS; LUNG NEOPLASMS; METABOLISM; NUDE MOUSE; PATHOLOGY; RUBUS; TUMOR CELL LINE;

GASTROPODA; MUS MUSCULUS; RUBUS IDAEUS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CADHERINS; CELL LINE, TUMOR; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; FOCAL ADHESION KINASE 1; HUMANS; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 2; MICE, INBRED BALB C; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PLANT EXTRACTS; RUBUS; TRANSCRIPTION FACTORS; UROKINASE-TYPE PLASMINOGEN ACTIVATOR; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84887510032     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.10.021     Document Type: Article

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