A fast-evolving human NPAS3 enhancer gained reporter expression in the developing forebrain of transgenic mice

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 368, Issue 1632, 2013, Pages

  Kamm, Gretel B ^a   López Leal, Rodrigo ^b   Lorenzo, Juan R ^a   Franchini, Lucía F ^a  

^a INSTITUTO DE INVESTIGACIONES EN INGENIERÍA GENÉTICA Y BIOLOGÍA MOLECULAR   (Argentina)

^b CENTRO DE ESTUDIOS CIENTÍFICOS CECS   (Chile)

Author keywords

Brain; Evolution; Exaptation; MIR; NPAS3; Schizophrenia

Indexed keywords

BRAIN; GENE EXPRESSION; GENETICALLY MODIFIED ORGANISM; HUMAN EVOLUTION; MOLECULAR ANALYSIS; NEUROLOGY; PRIMATE; RODENT;

5 BROMO 4 CHLORO 3 INDOLYL BETA GALACTOSIDE; 5-BROMO-4-CHLORO-3-INDOLYL BETA-GALACTOSIDE; GALACTOSIDE; INDOLE DERIVATIVE; NERVE PROTEIN; NPAS3 PROTEIN, HUMAN; PRIMER DNA; TRANSCRIPTION FACTOR;

ANIMAL; ARTICLE; BIOLOGY; BRAIN; ENHANCER REGION; EVOLUTION; EXAPTATION; FOREBRAIN; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LACTOSE OPERON; METABOLISM; MIR; MOLECULAR EVOLUTION; MOUSE; NPAS3; NUCLEOTIDE SEQUENCE; PAN TROGLODYTES; SCHIZOPHRENIA; SHORT INTERSPERSED REPEAT; SPECIES DIFFERENCE; TRANSGENIC MOUSE;

BRAIN; EVOLUTION; EXAPTATION; MIR; NPAS3; SCHIZOPHRENIA;

ANIMALS; COMPUTATIONAL BIOLOGY; CONSERVED SEQUENCE; DNA PRIMERS; ENHANCER ELEMENTS, GENETIC; EVOLUTION, MOLECULAR; GALACTOSIDES; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INDOLES; LAC OPERON; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; PAN TROGLODYTES; PROSENCEPHALON; SHORT INTERSPERSED NUCLEOTIDE ELEMENTS; SPECIES SPECIFICITY; TRANSCRIPTION FACTORS;

EID: 84887497668     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2013.0019     Document Type: Article

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