Retention of α-helical structure by HDL mimetic peptide ATI-5261 upon extensive dilution represents an important determinant for stimulating ABCA1 cholesterol efflux with high efficiency

Biochemical and Biophysical Research Communications

Volumn 441, Issue 1, 2013, Pages 71-76

  Zheng, Ying ^a   Patel, Arti B ^b   Narayanaswami, Vasanthy ^b,c   Bielicki, John K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CALIFORNIA STATE UNIVERSITY   (United States)

^c CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

Author keywords

Helix; Atherosclerosis; Cholesterol efflux; HDL mimetic peptides; Macrophages; Reverse cholesterol transport; Therapeutic peptides

Indexed keywords

ABC TRANSPORTER A1; AMINO ACID; ARGININE; ATI 5261; CHOLESTEROL; GLUTAMINE; PEPTIDE; PEPTIDOMIMETIC AGENT; UNCLASSIFIED DRUG; ABCA1 PROTEIN, MOUSE; ATI-5261; DIMYRISTOYLPHOSPHATIDYLCHOLINE; HIGH DENSITY LIPOPROTEIN;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DILUTION; HYDROPHOBICITY; MACROPHAGE; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; REDUCTION; STEREOSPECIFICITY; AMINO ACID SEQUENCE; ANIMAL; BIOPHYSICS; CELL LINE; CHEMISTRY; LIPID METABOLISM; METABOLISM; MOLECULAR GENETICS; MOUSE; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; TRANSPORT AT THE CELLULAR LEVEL;

AMINO ACID SEQUENCE; ANIMALS; ATP BINDING CASSETTE TRANSPORTER 1; BIOLOGICAL TRANSPORT; BIOPHYSICAL PHENOMENA; CELL LINE; CHOLESTEROL; DIMYRISTOYLPHOSPHATIDYLCHOLINE; LIPID METABOLISM; LIPOPROTEINS, HDL; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84887492227     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.10.017     Document Type: Article

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