Probing the non-canonical interface for agonist interaction with an α5 containing nicotinic acetylcholine receptor

Neuropharmacology

Volumn 77, Issue , 2014, Pages 342-349

  Marotta, Christopher B ^a   Dilworth, Crystal N ^a   Lester, Henry A ^b   Dougherty, Dennis A ^a  

^a California Institute of Technology   (United States)

^b California Institute of Technology   (United States)

Author keywords

Addiction; Biophysics; Cholinergic receptor; Electrophysiology; Ion channels; Nicotinic acetylcholine receptors

Indexed keywords

NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA4; NICOTINIC RECEPTOR ALPHA5; NICOTINIC RECEPTOR BETA2; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ELECTROPHYSIOLOGY; GAIN OF FUNCTION MUTATION; LIGAND BINDING; MOLECULAR PROBE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SUBUNIT; STOICHIOMETRY; STRUCTURE ACTIVITY RELATION;

A2B3; A3B2; ADDICTION; BIOPHYSICS; CENTRAL NERVOUS SYSTEM; CHOLINERGIC RECEPTOR; CNS; ELECTROPHYSIOLOGY; HIGH SENSITIVITY (Α4Β2)(2)(Β2) RECEPTOR; HILL COEFFICIENT; ION CHANNELS; LOW SENSITIVITY (Α4Β2)(2)(Α4) RECEPTOR; NACHR; NH; NICOTINIC ACETYLCHOLINE RECEPTOR; NICOTINIC ACETYLCHOLINE RECEPTORS; SEM; STANDARD ERROR OF THE MEAN;

ANIMALS; BINDING SITES; NICOTINE; PROTEIN SUBUNITS; RECEPTORS, NICOTINIC; XENOPUS LAEVIS;

EID: 84887455017     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.09.028     Document Type: Article

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