Adult neural stem cells and their niche: A dynamic duo during homeostasis, regeneration, and aging

Current Opinion in Neurobiology

Volumn 23, Issue 6, 2013, Pages 935-942

  Silva Vargas, Violeta ^a   Crouch, Elizabeth E ^a   Doetsch, Fiona ^a  

^a College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; GROWTH FACTOR;

ADULTHOOD; AGING; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; BRAIN VENTRICLE; CELL ADHESION; CELL INTERACTION; CEREBROSPINAL FLUID; EPENDYMA CELL; FEEDBACK SYSTEM; HOMEOSTASIS; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROANATOMY; NONHUMAN; PRIORITY JOURNAL; REGENERATION; REVIEW; SIGNAL TRANSDUCTION; STEM CELL NICHE; SUBVENTRICULAR ZONE;

ADULT STEM CELLS; AGING; ANIMALS; HOMEOSTASIS; HUMANS; NERVE REGENERATION; NEURAL STEM CELLS; NEUROGENESIS; STEM CELL NICHE;

EID: 84887411205     PISSN: 09594388     EISSN: 18736882     Source Type: Journal    
DOI: 10.1016/j.conb.2013.09.004     Document Type: Review

References (58)

1. Pastrana E., Silva-Vargas V., Doetsch F. Eyes wide open: a critical review of sphere-formation as an assay for stem cells. Cell Stem Cell 2011, 8:486-498.
2. Mirzadeh Z., Merkle F.T., Soriano-Navarro M., Garcia-Verdugo J.M., Alvarez-Buylla A. Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell 2008, 3:265-278.
3. Doetsch F., Alvarez-Buylla A. Network of tangential pathways for neuronal migration in adult mammalian brain. Proc Natl Acad Sci U S A 1996, 93:14895-14900.
4. Shen Q., Wang Y., Kokovay E., Lin G., Chuang S.M., Goderie S.K., Roysam B., Temple S. Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions. Cell Stem Cell 2008, 3:289-300.
5. Tavazoie M., Van der Veken L., Silva-Vargas V., Louissaint M., Colonna L., Zaidi B., Garcia-Verdugo J.M., Doetsch F. A specialized vascular niche for adult neural stem cells. Cell Stem Cell 2008, 3:279-288.
6. Fuentealba L.C., Obernier K., Alvarez-Buylla A. Adult neural stem cells bridge their niche. Cell Stem Cell 2012, 10:698-708.
7. Redzic Z.B., Preston J.E., Duncan J.A., Chodobski A., Szmydynger-Chodobska J. The choroid plexus-cerebrospinal fluid system: from development to aging. Curr Top Dev Biol 2005, 71:1-52.
8. Zappaterra M.W., Lehtinen M.K. The cerebrospinal fluid: regulator of neurogenesis, behavior, and beyond. Cell Mol Life Sci 2012, 69:2863-2878.
9. Lehtinen M.K., Zappaterra M.W., Chen X., Yang Y.J., Hill A.D., Lun M., Maynard T., Gonzalez D., Kim S., Ye P., et al. The cerebrospinal fluid provides a proliferative niche for neural progenitor cells. Neuron 2011, 69:893-905.
10. Lee C., Hu J., Ralls S., Kitamura T., Loh Y.P., Yang Y., Mukouyama Y.S., Ahn S. The molecular profiles of neural stem cell niche in the adult subventricular zone. PLoS ONE 2012, 7:e50501.
11. Marques F., Sousa J.C., Coppola G., Gao F., Puga R., Brentani H., Geschwind D.H., Sousa N., Correia-Neves M., Palha J.A. Transcriptome signature of the adult mouse choroid plexus. Fluids Barriers CNS 2011, 8:10.
12. Marzesco A.M., Janich P., Wilsch-Brauninger M., Dubreuil V., Langenfeld K., Corbeil D., Huttner W.B. Release of extracellular membrane particles carrying the stem cell marker prominin-1 (CD133) from neural progenitors and other epithelial cells. J Cell Sci 2005, 118:2849-2858.
13. Street J.M., Barran P.E., Mackay C.L., Weidt S., Balmforth C., Walsh T.S., Chalmers R.T., Webb D.J., Dear J.W. Identification and proteomic profiling of exosomes in human cerebrospinal fluid. J Transl Med 2012, 10:5.
14. Pan S., Zhu D., Quinn J.F., Peskind E.R., Montine T.J., Lin B., Goodlett D.R., Taylor G., Eng J., Zhang J. A combined dataset of human cerebrospinal fluid proteins identified by multi-dimensional chromatography and tandem mass spectrometry. Proteomics 2007, 7:469-473.
15. Pastrana E., Cheng L.C., Doetsch F. Simultaneous prospective purification of adult subventricular zone neural stem cells and their progeny. Proc Natl Acad Sci U S A 2009, 106:6387-6392.
16. Kerever A., Schnack J., Vellinga D., Ichikawa N., Moon C., Arikawa-Hirasawa E., Efird J.T., Mercier F. Novel extracellular matrix structures in the neural stem cell niche capture the neurogenic factor fibroblast growth factor 2 from the extracellular milieu. Stem Cells 2007, 25:2146-2157.
17. Sawamoto K., Wichterle H., Gonzalez-Perez O., Cholfin J.A., Yamada M., Spassky N., Murcia N.S., Garcia-Verdugo J.M., Marin O., Rubenstein J.L., et al. New neurons follow the flow of cerebrospinal fluid in the adult brain. Science 2006, 311:629-632.
18. Guirao B., Meunier A., Mortaud S., Aguilar A., Corsi J.M., Strehl L., Hirota Y., Desoeuvre A., Boutin C., Han Y.G., et al. Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia. Nat Cell Biol 2010, 12:341-350.
19. Doetsch F., Garcia-Verdugo J.M., Alvarez-Buylla A. Regeneration of a germinal layer in the adult mammalian brain. Proc Natl Acad Sci U S A 1999, 96:11619-11624.
20. Beckervordersandforth R., Tripathi P., Ninkovic J., Bayam E., Lepier A., Stempfhuber B., Kirchhoff F., Hirrlinger J., Haslinger A., Lie D.C., et al. In vivo fate mapping and expression analysis reveals molecular hallmarks of prospectively isolated adult neural stem cells. Cell Stem Cell 2010, 7:744-758.
21. Kriegstein A., Alvarez-Buylla A. The glial nature of embryonic and adult neural stem cells. Annu Rev Neurosci 2009, 32:149-184.
22. Kokovay E., Wang Y., Kusek G., Wurster R., Lederman P., Lowry N., Shen Q., Temple S. VCAM1 is essential to maintain the structure of the SVZ niche and acts as an environmental sensor to regulate SVZ lineage progression. Cell Stem Cell 2012, 11:220-230.
23. Lacar B., Young S.Z., Platel J.C., Bordey A. Gap junction-mediated calcium waves define communication networks among murine postnatal neural progenitor cells. Eur J Neurosci 2011, 34:1895-1905.
24. Aguirre A., Rubio M.E., Gallo V. Notch EGFR pathway interaction regulates neural stem cell number and self-renewal. Nature 2010, 467:323-327.
25. Young S.Z., Taylor M.M., Bordey A. Neurotransmitters couple brain activity to subventricular zone neurogenesis. Eur J Neurosci 2011, 33:1123-1132.
26. Fernando R.N., Eleuteri B., Abdelhady S., Nussenzweig A., Andang M., Ernfors P. Cell cycle restriction by histone H2AX limits proliferation of adult neural stem cells. Proc Natl Acad Sci U S A 2011, 108:5837-5842.
27. Alfonso J., Le Magueresse C., Zuccotti A., Khodosevich K., Monyer H. Diazepam binding inhibitor promotes progenitor proliferation in the postnatal SVZ by reducing GABA signaling. Cell Stem Cell 2012, 10:76-87.
28. Song J., Zhong C., Bonaguidi M.A., Sun G.J., Hsu D., Gu Y., Meletis K., Huang Z.J., Ge S., Enikolopov G., et al. Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision. Nature 2012, 489:150-154.
29. Lennington J.B., Pope S., Goodheart A.E., Drozdowicz L., Daniels S.B., Salamone J.D., Conover J.C. Midbrain dopamine neurons associated with reward processing innervate the neurogenic subventricular zone. J Neurosci 2011, 31:13078-13087.
30. Matarredona E.R., Murillo-Carretero M., Moreno-Lopez B., Estrada C. Role of nitric oxide in subventricular zone neurogenesis. Brain Res Brain Res Rev 2005, 49:355-366.
31. Simpson K.L., Fisher T.M., Waterhouse B.D., Lin R.C. Projection patterns from the raphe nuclear complex to the ependymal wall of the ventricular system in the rat. J Comp Neurol 1998, 399:61-72.
32. Vukovic J., Colditz M.J., Blackmore D.G., Ruitenberg M.J., Bartlett P.F. Microglia modulate hippocampal neural precursor activity in response to exercise and aging. J Neurosci 2012, 32:6435-6443.
33. Sierra A., Encinas J.M., Deudero J.J., Chancey J.H., Enikolopov G., Overstreet-Wadiche L.S., Tsirka S.E., Maletic-Savatic M. Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. Cell Stem Cell 2010, 7:483-495.
34. Mosher K.I., Andres R.H., Fukuhara T., Bieri G., Hasegawa-Moriyama M., He Y., Guzman R., Wyss-Coray T. Neural progenitor cells regulate microglia functions and activity. Nat Neurosci 2012, 15:1485-1487.
35. Palmer T.D., Willhoite A.R., Gage F.H. Vascular niche for adult hippocampal neurogenesis. J Comp Neurol 2000, 425:479-494.
36. Mercier F., Kitasako J.T., Hatton G.I. Anatomy of the brain neurogenic zones revisited: fractones and the fibroblast/macrophage network. J Comp Neurol 2002, 451:170-188.
37. Douet V., Arikawa-Hirasawa E., Mercier F. Fractone-heparan sulfates mediate BMP-7 inhibition of cell proliferation in the adult subventricular zone. Neurosci Lett 2012, 528:120-125.
38. Kazanis I., Lathia J.D., Vadakkan T.J., Raborn E., Wan R., Mughal M.R., Eckley D.M., Sasaki T., Patton B., Mattson M.P., et al. Quiescence and activation of stem and precursor cell populations in the subependymal zone of the mammalian brain are associated with distinct cellular and extracellular matrix signals. J Neurosci 2010, 30:9771-9781.
39. Niola F., Zhao X., Singh D., Castano A., Sullivan R., Lauria M., Nam H.S., Zhuang Y., Benezra R., Di Bernardo D., et al. Id proteins synchronize stemness and anchorage to the niche of neural stem cells. Nat Cell Biol 2012, 14:477-487.
40. Culver J.C., Vadakkan T.J., Dickinson M.E. A specialized microvascular domain in the mouse neural stem cell niche. PLoS ONE 2013, 8:e53546.
41. Gomez-Gaviro M.V., Scott C.E., Sesay A.K., Matheu A., Booth S., Galichet C., Lovell-Badge R. Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis. Proc Natl Acad Sci U S A 2012, 109:1317-1322.
42. Ramirez-Castillejo C., Sanchez-Sanchez F., Andreu-Agullo C., Ferron S.R., Aroca-Aguilar J.D., Sanchez P., Mira H., Escribano J., Farinas I. Pigment epithelium-derived factor is a niche signal for neural stem cell renewal. Nat Neurosci 2006, 9:331-339.
43. Kokovay E., Goderie S., Wang Y., Lotz S., Lin G., Sun Y., Roysam B., Shen Q., Temple S. Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling. Cell Stem Cell 2010, 7:163-173.
44. Mathieu C., Sii-Felice K., Fouchet P., Etienne O., Haton C., Mabondzo A., Boussin F.D., Mouthon M.A. Endothelial cell-derived bone morphogenetic proteins control proliferation of neural stem/progenitor cells. Mol Cell Neurosci 2008, 38:569-577.
45. Lacar B., Herman P., Platel J.C., Kubera C., Hyder F., Bordey A. Neural progenitor cells regulate capillary blood flow in the postnatal subventricular zone. J Neurosci 2012, 32:16435-16448.
46. Crisan M., Yap S., Casteilla L., Chen C.W., Corselli M., Park T.S., Andriolo G., Sun B., Zheng B., Zhang L., et al. A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell 2008, 3:301-313.
47. Paul G., Ozen I., Christophersen N.S., Reinbothe T., Bengzon J., Visse E., Jansson K., Dannaeus K., Henriques-Oliveira C., Roybon L., et al. The adult human brain harbors multipotent perivascular mesenchymal stem cells. PLoS ONE 2012, 7:e35577.
48. Signer R.A., Morrison S.J. Mechanisms that regulate stem cell aging and life span. Cell Stem Cell 2013, 12:152-165.
49. Conover J.C., Shook B.A. Aging of the subventricular zone neural stem cell niche. Aging Dis 2011, 2:149-163.
50. Bouab M., Paliouras G.N., Aumont A., Forest-Berard K., Fernandes K.J. Aging of the subventricular zone neural stem cell niche: evidence for quiescence-associated changes between early and mid-adulthood. Neuroscience 2011, 173:135-149.
51. Jin K., Sun Y., Xie L., Batteur S., Mao X.O., Smelick C., Logvinova A., Greenberg D.A. Neurogenesis and aging: FGF-2 and HB-EGF restore neurogenesis in hippocampus and subventricular zone of aged mice. Aging Cell 2003, 2:175-183.
52. Pineda J.R., Daynac M., Chicheportiche A., Cebrian-Silla A., Sii Felice K., Garcia-Verdugo J.M., Boussin F.D., Mouthon M.A. Vascular-derived TGF-beta increases in the stem cell niche and perturbs neurogenesis during aging and following irradiation in the adult mouse brain. EMBO Mol Med 2013, 5:548-562.
53. Shook B.A., Manz D.H., Peters J.J., Kang S., Conover J.C. Spatiotemporal changes to the subventricular zone stem cell pool through aging. J Neurosci 2012, 32:6947-6956.
54. Villeda S.A., Luo J., Mosher K.I., Zou B., Britschgi M., Bieri G., Stan T.M., Fainberg N., Ding Z., Eggel A., et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 2011, 477:90-94.
55. Lugert S., Basak O., Knuckles P., Haussler U., Fabel K., Gotz M., Haas C.A., Kempermann G., Taylor V., Giachino C. Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging. Cell Stem Cell 2010, 6:445-456.
56. Dranovsky A., Picchini A.M., Moadel T., Sisti A.C., Yamada A., Kimura S., Leonardo E.D., Hen R. Experience dictates stem cell fate in the adult hippocampus. Neuron 2011, 70:908-923.
57. Blackmore D.G., Golmohammadi M.G., Large B., Waters M.J., Rietze R.L. Exercise increases neural stem cell number in a growth hormone-dependent manner, augmenting the regenerative response in aged mice. Stem Cells 2009, 27:2044-2052.
58. Christie K.J., Turnley A.M. Regulation of endogenous neural stem/progenitor cells for neural repair-factors that promote neurogenesis and gliogenesis in the normal and damaged brain. Front Cell Neurosci 2012, 6:70.