-
1
-
-
84856487711
-
Prevalence of obesity and trends in the distribution of body mass index among US adults 1999-2010
-
Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. JAMA 307(5), 491-497 (2012
-
(2012)
JAMA
, vol.307
, Issue.5
, pp. 491-497
-
-
Flegal, K.M.1
Carroll, M.D.2
Kit, B.K.3
Ogden, C.L.4
-
2
-
-
35748946267
-
Economic consequences of the obese
-
Runge CF. Economic consequences of the obese. Diabetes 56(11), 2668-2672 (2007
-
(2007)
Diabetes
, vol.56
, Issue.11
, pp. 2668-2672
-
-
Runge, C.F.1
-
3
-
-
2942675088
-
Obesity, metabolic syndrome, and cardiovascular disease
-
Grundy SM. Obesity, metabolic syndrome, and cardiovascular disease. J. Clin. Endocrinol. Metab. 89(6), 2595-2600 (2004
-
(2004)
J. Clin. Endocrinol. Metab
, vol.89
, Issue.6
, pp. 2595-2600
-
-
Grundy, S.M.1
-
4
-
-
33845886915
-
Abdominal obesity and metabolic syndrome
-
Despres JP, Lemieux I. Abdominal obesity and metabolic syndrome. Nature 444(7121), 881-887 (2006
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 881-887
-
-
Despres, J.P.1
Lemieux, I.2
-
5
-
-
4444382796
-
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the interheart study): Case-control study
-
Yusuf S, Hawken S, Ounpuu S et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study. Lancet 364(9438), 937-952 (2004
-
(2004)
Lancet
, vol.364
, Issue.9438
, pp. 937-952
-
-
Yusuf, S.1
Hawken, S.2
Ounpuu, S.3
-
6
-
-
34347351228
-
Abdominal visceral and subcutaneous adipose tissue compartments: Association with metabolic risk factors in the framingham heart study
-
Fox CS, Massaro JM, Hoffmann U et al. Abdominal visceral and subcutaneous adipose tissue compartments: Association with metabolic risk factors in the Framingham Heart Study. Circulation 116(1), 39-48 (2007
-
(2007)
Circulation
, vol.116
, Issue.1
, pp. 39-48
-
-
Fox, C.S.1
Massaro, J.M.2
Hoffmann, U.3
-
7
-
-
34249939788
-
Cardiovascular disease under the influence of excess visceral fat
-
Despres JP. Cardiovascular disease under the influence of excess visceral fat. Crit. Pathw. Cardiol. 6(2), 51-59 (2007
-
(2007)
Crit. Pathw. Cardiol
, vol.6
, Issue.2
, pp. 51-59
-
-
Despres, J.P.1
-
8
-
-
80051772066
-
Obesity and dyslipidemia
-
Franssen R, Monajemi H, Stroes ES, Kastelein JJ. Obesity and dyslipidemia. Med. Clin. North Am. 95(5), 893-902 (2011
-
(2011)
Med. Clin. North Am.
, vol.95
, Issue.5
, pp. 893-902
-
-
Franssen, R.1
Monajemi, H.2
Stroes, E.S.3
Kastelein, J.J.4
-
9
-
-
84859184996
-
Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: A meta-Analysis
-
Boekholdt SM, Arsenault BJ, Mora S et al. Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: A meta-Analysis. JAMA 307(12), 1302-1309 (2012).
-
(2012)
JAMA
, vol.307
, Issue.12
, pp. 1302-1309
-
-
Boekholdt, S.M.1
Arsenault, B.J.2
Mora, S.3
-
10
-
-
84861227320
-
The role of non-HDL cholesterol in risk stratification for coronary artery disease
-
Rana JS, Boekholdt SM, Kastelein JJ, Shah PK. The role of non-HDL cholesterol in risk stratification for coronary artery disease. Curr. Atheroscler. Rep. 14(2), 130-134 (2012
-
(2012)
Curr. Atheroscler. Rep
, vol.14
, Issue.2
, pp. 130-134
-
-
Rana, J.S.1
Boekholdt, S.M.2
Kastelein, J.J.3
Shah, P.K.4
-
11
-
-
46249093117
-
Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome
-
Adiels M, Olofsson SO, Taskinen MR, Boren J. Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome. Arterioscler. Thromb. Vasc. Biol. 28(7), 1225-1236 (2008
-
(2008)
Arterioscler. Thromb. Vasc. Biol
, vol.28
, Issue.7
, pp. 1225-1236
-
-
Adiels, M.1
Olofsson, S.O.2
Taskinen, M.R.3
Boren, J.4
-
12
-
-
33646885074
-
Diabetic dyslipidaemia
-
Adiels M, Olofsson SO, Taskinen MR, Boren J. Diabetic dyslipidaemia. Curr. Opin. Lipidol. 17(3), 238-246 (2006
-
(2006)
Curr. Opin. Lipidol
, vol.17
, Issue.3
, pp. 238-246
-
-
Adiels, M.1
Olofsson, S.O.2
Taskinen, M.R.3
Boren, J.4
-
13
-
-
0037898380
-
Diabetic dyslipidaemia: From basic research to clinical practice
-
Taskinen MR. Diabetic dyslipidaemia: From basic research to clinical practice. Diabetologia 46(6), 733-749 (2003
-
(2003)
Diabetologia
, vol.46
, Issue.6
, pp. 733-749
-
-
Taskinen, M.R.1
-
14
-
-
1842767407
-
The relationship between cholesteryl ester transfer protein levels and risk factor profile in patients with familial hypercholesterolemia
-
de Grooth GJ, Smilde TJ, Van WS et al. The relationship between cholesteryl ester transfer protein levels and risk factor profile in patients with familial hypercholesterolemia. Atherosclerosis 173(2), 261-267 (2004
-
(2004)
Atherosclerosis
, vol.173
, Issue.2
, pp. 261-267
-
-
De Grooth, G.J.1
Smilde, T.J.2
Van, W.S.3
-
15
-
-
34247882089
-
Obesity and atherogenic dyslipidemia
-
Bamba V, Rader DJ. Obesity and atherogenic dyslipidemia. Gastroenterology 132(6), 2181-2190 (2007
-
(2007)
Gastroenterology
, vol.132
, Issue.6
, pp. 2181-2190
-
-
Bamba, V.1
Rader, D.J.2
-
16
-
-
84865523163
-
Selective hepatic insulin resistance vldl overproduction, and hypertriglyceridemia
-
Sparks JD, Sparks CE, Adeli K. Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia. Arterioscler. Thromb. Vasc. Biol. 32(9), 2104-2112 (2012
-
(2012)
Arterioscler. Thromb. Vasc. Biol
, vol.32
, Issue.9
, pp. 2104-2112
-
-
Sparks, J.D.1
Sparks, C.E.2
Adeli, K.3
-
17
-
-
33748516743
-
Insulin sensitisation affects lipoprotein lipase transport in Type 2 diabetes: Role of adipose tissue and skeletal muscle in response to rosiglitazone
-
Tan GD, Olivecrona G, Vidal H, Frayn KN, Karpe F. Insulin sensitisation affects lipoprotein lipase transport in Type 2 diabetes: Role of adipose tissue and skeletal muscle in response to rosiglitazone. Diabetologia 49(10), 2412-2418 (2006
-
(2006)
Diabetologia
, vol.49
, Issue.10
, pp. 2412-2418
-
-
Tan, G.D.1
Olivecrona, G.2
Vidal, H.3
Frayn, K.N.4
Karpe, F.5
-
18
-
-
5444267382
-
Increased apoC-III production is a characteristic feature of patients with hypertriglyceridemia
-
Cohn JS, Tremblay M, Batal R et al. Increased apoC-III production is a characteristic feature of patients with hypertriglyceridemia. Atherosclerosis 177(1), 137-145 (2004
-
(2004)
Atherosclerosis
, vol.177
, Issue.1
, pp. 137-145
-
-
Cohn, J.S.1
Tremblay, M.2
Batal, R.3
-
19
-
-
77953231023
-
Decreased apolipoprotein A5 is implicated in insulin resistance-related hypertriglyceridemia in obesity
-
Huang XS, Zhao SP, Hu M, Bai L, Zhang Q, Zhao W. Decreased apolipoprotein A5 is implicated in insulin resistance-related hypertriglyceridemia in obesity. Atherosclerosis 210(2), 563-568 (2010
-
(2010)
Atherosclerosis
, vol.210
, Issue.2
, pp. 563-568
-
-
Huang, X.S.1
Zhao, S.P.2
Hu, M.3
Bai, L.4
Zhang, Q.5
Zhao, W.6
-
20
-
-
20144375048
-
Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase
-
Merkel M, Loeffler B, Kluger M et al. Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase. J. Biol. Chem. 280(22), 21553-21560 (2005
-
(2005)
J. Biol. Chem
, vol.280
, Issue.22
, pp. 21553-21560
-
-
Merkel, M.1
Loeffler, B.2
Kluger, M.3
-
21
-
-
0037603589
-
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
-
Abifadel M, Varret M, Rabes JP et al. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat. Genet. 34(2), 154-156 (2003
-
(2003)
Nat. Genet
, vol.34
, Issue.2
, pp. 154-156
-
-
Abifadel, M.1
Varret, M.2
Rabes, J.P.3
-
22
-
-
17244377696
-
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9
-
Rashid S, Curtis DE, Garuti R et al. Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9. Proc. Natl Acad. Sci. USA 102(15), 5374-5379 (2005
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, Issue.15
, pp. 5374-5379
-
-
Rashid, S.1
Curtis, D.E.2
Garuti, R.3
-
23
-
-
33645103550
-
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
-
Cohen JC, Boerwinkle E, Mosley TH Jr, Hobbs HH. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N. Engl. J. Med. 354(12), 1264-1272 (2006
-
(2006)
N. Engl. J. Med
, vol.354
, Issue.12
, pp. 1264-1272
-
-
Cohen, J.C.1
Boerwinkle, E.2
Mosley Jr., T.H.3
Hobbs, H.H.4
-
24
-
-
3943090528
-
Apolipoprotein B100 metabolism in autosomal-dominant hypercholesterolemia related to mutations in PCSK9
-
Ouguerram K, Chetiveaux M, Zair Y et al. Apolipoprotein B100 metabolism in autosomal-dominant hypercholesterolemia related to mutations in PCSK9. Arterioscler. Thromb. Vasc. Biol. 24(8), 1448-1453 (2004
-
(2004)
Arterioscler. Thromb. Vasc. Biol
, vol.24
, Issue.8
, pp. 1448-1453
-
-
Ouguerram, K.1
Chetiveaux, M.2
Zair, Y.3
-
25
-
-
77953958749
-
Increased secretion of lipoproteins in transgenic mice expressing human D374Y PCSK9 under physiological genetic control
-
Herbert B, Patel D, Waddington SN et al. Increased secretion of lipoproteins in transgenic mice expressing human D374Y PCSK9 under physiological genetic control. Arterioscler. Thromb. Vasc. Biol. 30(7), 1333-1339 (2010
-
(2010)
Arterioscler. Thromb. Vasc. Biol
, vol.30
, Issue.7
, pp. 1333-1339
-
-
Herbert, B.1
Patel, D.2
Waddington, S.N.3
-
26
-
-
67650263873
-
Genetic and metabolic determinants of plasma PCSK9 levels
-
Lakoski SG, Lagace TA, Cohen JC, Horton JD, Hobbs HH. Genetic and metabolic determinants of plasma PCSK9 levels. J. Clin. Endocrinol. Metab. 94(7), 2537-2543 (2009
-
(2009)
J. Clin. Endocrinol. Metab
, vol.94
, Issue.7
, pp. 2537-2543
-
-
Lakoski, S.G.1
Lagace, T.A.2
Cohen, J.C.3
Horton, J.D.4
Hobbs, H.H.5
-
27
-
-
69549138572
-
Plasma PCSK9 is associated with age, sex, and multiple metabolic markers in a population-based sample of children and adolescents
-
Baass A, Dubuc G, Tremblay M et al. Plasma PCSK9 is associated with age, sex, and multiple metabolic markers in a population-based sample of children and adolescents. Clin. Chem. 55(9), 1637-1645 (2009
-
(2009)
Clin. Chem
, vol.55
, Issue.9
, pp. 1637-1645
-
-
Baass, A.1
Dubuc, G.2
Tremblay, M.3
-
28
-
-
84871942788
-
Plasma PCSK9 concentrations during an oral fat load and after short term high-fat, high-fat high-protein and high-fructose diets
-
Cariou B, Langhi C, Le BM et al. Plasma PCSK9 concentrations during an oral fat load and after short term high-fat, high-fat high-protein and high-fructose diets. Nutr. Metab. (Lond). 10(1), 4-10 (2013
-
(2013)
Nutr. Metab. (Lond
, vol.10
, Issue.1
, pp. 4-10
-
-
Cariou, B.1
Langhi C Le, B.M.2
-
29
-
-
2342451128
-
Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype
-
Maxwell KN, Breslow JL. Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype. Proc. Natl Acad. Sci. USA 101(18), 7100-7105 (2004
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.18
, pp. 7100-7105
-
-
Maxwell, K.N.1
Breslow, J.L.2
-
30
-
-
9644266673
-
Post-Transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver
-
Park SW, Moon YA, Horton JD. Post-Transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver. J. Biol. Chem. 279(48), 50630-50638 (2004
-
(2004)
J. Biol. Chem
, vol.279
, Issue.48
, pp. 50630-50638
-
-
Park, S.W.1
Moon, Y.A.2
Horton, J.D.3
-
31
-
-
33748752232
-
Fasting induces hyperlipidemia in mice overexpressing proprotein convertase subtilisin kexin type 9: Lack of modulation of very-low-density lipoprotein hepatic output by the low-density lipoprotein receptor
-
Lambert G, Jarnoux AL, Pineau T et al. Fasting induces hyperlipidemia in mice overexpressing proprotein convertase subtilisin kexin type 9: Lack of modulation of very-low-density lipoprotein hepatic output by the low-density lipoprotein receptor. Endocrinology 147(10), 4985-4995 (2006
-
(2006)
Endocrinology
, vol.147
, Issue.10
, pp. 4985-4995
-
-
Lambert, G.1
Jarnoux, A.L.2
Pineau, T.3
-
32
-
-
85027929193
-
Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor
-
Sun H, Samarghandi A, Zhang N, Yao Z, Xiong M, Teng BB. Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor. Arterioscler. Thromb. Vasc. Biol. 32(7), 1585-1595 (2012
-
(2012)
Arterioscler. Thromb. Vasc. Biol
, vol.32
, Issue.7
, pp. 1585-1595
-
-
Sun, H.1
Samarghandi, A.2
Zhang, N.3
Yao, Z.4
Xiong, M.5
Teng, B.B.6
-
33
-
-
0037007109
-
Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein B
-
Gillian-Daniel DL, Bates PW, Tebon A, Attie AD. Endoplasmic reticulum localization of the low density lipoprotein receptor mediates presecretory degradation of apolipoprotein B. Proc. Natl Acad. Sci. USA 99(7), 4337-4342 (2002
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, Issue.7
, pp. 4337-4342
-
-
Gillian-Daniel, D.L.1
Bates, P.W.2
Tebon, A.3
Attie, A.D.4
-
34
-
-
45549096592
-
Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB
-
Blasiole DA, Oler AT, Attie AD. Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB. J. Biol. Chem. 283(17), 11374-11381 (2008
-
(2008)
J. Biol. Chem
, vol.283
, Issue.17
, pp. 11374-11381
-
-
Blasiole, D.A.1
Oler, A.T.2
Attie, A.D.3
-
35
-
-
79957923056
-
Unexpected roles for PCSK9 in lipid metabolism
-
Soutar AK. Unexpected roles for PCSK9 in lipid metabolism. Curr. Opin. Lipidol. 22(3), 192-196 (2011
-
(2011)
Curr. Opin. Lipidol
, vol.22
, Issue.3
, pp. 192-196
-
-
Soutar, A.K.1
-
36
-
-
78149300891
-
Fasting reduces plasma proprotein convertase, subtilisin/ kexin type 9 and cholesterol biosynthesis in humans
-
Browning JD, Horton JD. Fasting reduces plasma proprotein convertase, subtilisin/ kexin type 9 and cholesterol biosynthesis in humans. J. Lipid Res. 51(11), 3359-3363 (2010
-
(2010)
J. Lipid Res
, vol.51
, Issue.11
, pp. 3359-3363
-
-
Browning, J.D.1
Horton, J.D.2
-
37
-
-
84859717544
-
Regulation of hepatic ldl receptors by mtorc1 and pcsk9 in mice
-
Ai D, Chen C, Han S et al. Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice. J. Clin. Invest. 122(4), 1262-1270 (2012
-
(2012)
J. Clin. Invest
, vol.122
, Issue.4
, pp. 1262-1270
-
-
Ai, D.1
Chen, C.2
Han, S.3
-
38
-
-
0035905758
-
The hormone resistin links obesity to diabetes
-
Steppan CM, Bailey ST, Bhat S et al. The hormone resistin links obesity to diabetes. Nature 409(6818), 307-312 (2001
-
(2001)
Nature
, vol.409
, Issue.6818
, pp. 307-312
-
-
Steppan, C.M.1
Bailey, S.T.2
Bhat, S.3
-
40
-
-
67649869416
-
Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice
-
Qatanani M, Szwergold NR, Greaves DR, Ahima RS, Lazar MA. Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice. J. Clin. Invest. 119(3), 531-539 (2009
-
(2009)
J. Clin. Invest
, vol.119
, Issue.3
, pp. 531-539
-
-
Qatanani, M.1
Szwergold, N.R.2
Greaves, D.R.3
Ahima, R.S.4
Lazar, M.A.5
-
42
-
-
4644226667
-
Resistin, adiponectin, ghrelin, leptin, and proinflammatory cytokines: Relationships in obesity
-
Vendrell J, Broch M, Vilarrasa N et al. Resistin, adiponectin, ghrelin, leptin, and proinflammatory cytokines: Relationships in obesity. Obes. Res. 12(6), 962-971 (2004
-
(2004)
Obes. Res
, vol.12
, Issue.6
, pp. 962-971
-
-
Vendrell, J.1
Broch, M.2
Vilarrasa, N.3
-
43
-
-
8444235048
-
Identification of variables influencing resistin serum levels in patients with Type 1 and Type 2 diabetes mellitus
-
Schaffler A, Buchler C, Muller-Ladner U et al. Identification of variables influencing resistin serum levels in patients with Type 1 and Type 2 diabetes mellitus. Horm. Metab. Res. 36(10), 702-707 (2004
-
(2004)
Horm. Metab. Res
, vol.36
, Issue.10
, pp. 702-707
-
-
Schaffler, A.1
Buchler, C.2
Muller-Ladner, U.3
-
44
-
-
1242313298
-
Correlation between serum resistin level and adiposity in obese individuals
-
Azuma K, Katsukawa F, Oguchi S et al. Correlation between serum resistin level and adiposity in obese individuals. Obes. Res. 11(8), 997-1001 (2003
-
(2003)
Obes. Res
, vol.11
, Issue.8
, pp. 997-1001
-
-
Azuma, K.1
Katsukawa, F.2
Oguchi, S.3
-
45
-
-
39849086222
-
Resistin increases with obesity and atherosclerotic risk factors in patients with myocardial infarction
-
Piestrzeniewicz K, Luczak K, Komorowski J, Maciejewski M, Jankiewicz WJ, Goch JH. Resistin increases with obesity and atherosclerotic risk factors in patients with myocardial infarction. Metabolism 57(4), 488-493 (2008
-
(2008)
Metabolism
, vol.57
, Issue.4
, pp. 488-493
-
-
Piestrzeniewicz, K.1
Luczak, K.2
Komorowski, J.3
Maciejewski, M.4
Jankiewicz, W.J.5
Goch, J.H.6
-
46
-
-
2342453229
-
High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in Pima Indians
-
Vozarova de Court, Degawa-Yamauchi M, Considine RV, Tataranni PA. High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in Pima Indians. Diabetes 53(5), 1279-1284 (2004
-
(2004)
Diabetes
, vol.53
, Issue.5
, pp. 1279-1284
-
-
Vozarova De, Court.1
Degawa-Yamauchi, M.2
Considine, R.V.3
Tataranni, P.A.4
-
47
-
-
0038359739
-
Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans
-
Yannakoulia M, Yiannakouris N, Bluher S, Matalas AL, Klimis-Zacas D, Mantzoros CS. Body fat mass and macronutrient intake in relation to circulating soluble leptin receptor, free leptin index, adiponectin, and resistin concentrations in healthy humans. J. Clin. Endocrinol. Metab. 88(4), 1730-1736 (2003
-
(2003)
J. Clin. Endocrinol. Metab
, vol.88
, Issue.4
, pp. 1730-1736
-
-
Yannakoulia, M.1
Yiannakouris, N.2
Bluher, S.3
Matalas, A.L.4
Klimis-Zacas, D.5
Mantzoros, C.S.6
-
48
-
-
14044257211
-
Resistin is an inflammatory marker of atherosclerosis in humans
-
Reilly MP, Lehrke M, Wolfe ML, Rohatgi A, Lazar MA, Rader DJ. Resistin is an inflammatory marker of atherosclerosis in humans. Circulation 111(7), 932-939 (2005
-
(2005)
Circulation
, vol.111
, Issue.7
, pp. 932-939
-
-
Reilly, M.P.1
Lehrke, M.2
Wolfe, M.L.3
Rohatgi, A.4
Lazar, M.A.5
Rader, D.J.6
-
49
-
-
33947725216
-
Plasma resistin levels correlate with determinants of the metabolic syndrome
-
Norata GD, Ongari M, Garlaschelli K, Raselli S, Grigore L, Catapano AL. Plasma resistin levels correlate with determinants of the metabolic syndrome. Eur. J. Endocrinol. 156(2), 279-284 (2007
-
(2007)
Eur. J. Endocrinol
, vol.156
, Issue.2
, pp. 279-284
-
-
Norata, G.D.1
Ongari, M.2
Garlaschelli, K.3
Raselli, S.4
Grigore, L.5
Catapano, A.L.6
-
50
-
-
79953056591
-
Human resistin stimulates hepatic overproduction of atherogenic ApoB-containing lipoprotein particles by enhancing ApoB stability and impairing intracellular insulin signaling
-
Costandi J, Melone M, Zhao A, Rashid S. Human resistin stimulates hepatic overproduction of atherogenic ApoB-containing lipoprotein particles by enhancing ApoB stability and impairing intracellular insulin signaling. Circ. Res. 108(6), 727-742 (2011
-
(2011)
Circ. Res
, vol.108
, Issue.6
, pp. 727-742
-
-
Costandi, J.1
Melone, M.2
Zhao, A.3
Rashid, S.4
-
51
-
-
0034800255
-
Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance
-
Adeli K, Taghibiglou C, Van Iderstine SC, Lewis GF. Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance. Trends Cardiovasc. Med. 11(5), 170-176 (2001
-
(2001)
Trends Cardiovasc. Med
, vol.11
, Issue.5
, pp. 170-176
-
-
Adeli, K.1
Taghibiglou, C.2
Van Iderstine, S.C.3
Lewis, G.F.4
-
52
-
-
84860465539
-
Discovery of a new role of human resistin in hepatocyte low-density lipoprotein receptor suppression mediated in part by proprotein convertase subtilisin/ kexin type 9
-
Melone M, Wilsie L, Palyha O, Strack A, Rashid S. Discovery of a new role of human resistin in hepatocyte low-density lipoprotein receptor suppression mediated in part by proprotein convertase subtilisin/ kexin type 9. J. Am. Coll. Cardiol. 59(19), 1697-1705 (2012
-
(2012)
J. Am. Coll. Cardiol
, vol.59
, Issue.19
, pp. 1697-1705
-
-
Melone, M.1
Wilsie, L.2
Palyha, O.3
Strack, A.4
Rashid, S.5
-
53
-
-
84860475646
-
Proprotein convertase subtilisin/kexin type 9 as transducer of physiologic influences on cellular cholesterol: A case for resistin
-
Fazio S, Linton MF. Proprotein convertase subtilisin/kexin type 9 as transducer of physiologic influences on cellular cholesterol: A case for resistin. J. Am. Coll. Cardiol. 59(19), 1706-1708 (2012
-
(2012)
J. Am. Coll. Cardiol
, vol.59
, Issue.19
, pp. 1706-1708
-
-
Fazio, S.1
Linton, M.F.2
-
54
-
-
79958148945
-
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: Evidence and guidance for management
-
Chapman MJ, Ginsberg HN, Amarenco P et al. Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: Evidence and guidance for management. Eur. Heart J. 32(11), 1345-1361 (2011
-
(2011)
Eur. Heart J.
, vol.32
, Issue.11
, pp. 1345-1361
-
-
Chapman, M.J.1
Ginsberg, H.N.2
Amarenco, P.3
-
55
-
-
56349154187
-
The residual risk reduction initiative: A call to action to reduce residual vascular risk in patients with dyslipidemia
-
Suppl
-
Fruchart JC, Sacks F, Hermans MP et al. The Residual Risk Reduction Initiative: A call to action to reduce residual vascular risk in patients with dyslipidemia. Am. J. Cardiol. 102(10 Suppl.), 1K-34K (2008
-
(2008)
Am. J. Cardiol
, vol.102
, Issue.10
-
-
Fruchart, J.C.1
Sacks, F.2
Hermans, M.P.3
-
56
-
-
84855171302
-
Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy
-
Boden WE, Probstfield JL, Anderson T et al. Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy. N. Engl. J. Med. 365(24), 2255-2267 (2011
-
(2011)
N. Engl. J. Med
, vol.365
, Issue.24
, pp. 2255-2267
-
-
Boden, W.E.1
Probstfield, J.L.2
Anderson, T.3
-
57
-
-
84870556149
-
Management of dyslipidemias in the presence of the metabolic syndrome or Type 2 diabetes
-
Matikainen N, Taskinen MR. Management of dyslipidemias in the presence of the metabolic syndrome or Type 2 diabetes. Curr. Cardiol. Rep. 14(6), 721-731 (2012
-
(2012)
Curr. Cardiol. Rep
, vol.14
, Issue.6
, pp. 721-731
-
-
Matikainen, N.1
Taskinen, M.R.2
-
58
-
-
85027956505
-
Triglycerides: A case for treatment?
-
Wierzbicki AS, Clarke RE, Viljoen A, Mikhailidis DP. Triglycerides: A case for treatment? Curr. Opin. Cardiol. 27(4), 398-404 (2012
-
(2012)
Curr. Opin. Cardiol
, vol.27
, Issue.4
, pp. 398-404
-
-
Wierzbicki, A.S.1
Clarke, R.E.2
Viljoen, A.3
Mikhailidis, D.P.4
-
59
-
-
26944472828
-
A quantitative analysis of fish consumption and coronary heart disease mortality
-
Konig A, Bouzan C, Cohen JT et al. A quantitative analysis of fish consumption and coronary heart disease mortality. Am. J. Prev. Med. 29(4), 335-346 (2005
-
(2005)
Am. J. Prev. Med
, vol.29
, Issue.4
, pp. 335-346
-
-
Konig, A.1
Bouzan, C.2
Cohen, J.T.3
-
60
-
-
80051784104
-
Eicosapentaenoic acid ethyl ester (amr101) therapy in patients with very high triglyceride levels (from the multi-center, placebo-controlled, randomized, double-blind, 12-week study with an open-label extension [marine] trial
-
Bays HE, Ballantyne CM, Kastelein JJ, Isaacsohn JL, Braeckman RA, Soni PN. Eicosapentaenoic acid ethyl ester (AMR101) therapy in patients with very high triglyceride levels (from the Multi-center, plAcebo-controlled, Randomized, double-blINd, 12-week study with an open-label Extension [MARINE] trial). Am. J. Cardiol. 108(5), 682-690 (2011
-
(2011)
Am. J. Cardiol
, vol.108
, Issue.5
, pp. 682-690
-
-
Bays, H.E.1
Ballantyne, C.M.2
Kastelein, J.J.3
Isaacsohn, J.L.4
Braeckman, R.A.5
Soni, P.N.6
-
61
-
-
84866124338
-
Efficacy and safety of eicosapentaenoic acid ethyl ester (amr101) therapy in statin-Treated patients with persistent high triglycerides (from the anchor study
-
Ballantyne CM, Bays HE, Kastelein JJ et al. Efficacy and safety of eicosapentaenoic acid ethyl ester (AMR101) therapy in statin-Treated patients with persistent high triglycerides (from the ANCHOR study). Am. J. Cardiol. 110(7), 984-992 (2012
-
(2012)
Am. J. Cardiol
, vol.110
, Issue.7
, pp. 984-992
-
-
Ballantyne, C.M.1
Bays, H.E.2
Kastelein, J.J.3
-
62
-
-
84878637167
-
Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans
-
Graham MJ, Lee RG, Bell TA, III et al. Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans. Circ. Res. 112(11), 1479-1490 (2013
-
(2013)
Circ. Res
, vol.112
, Issue.11
, pp. 1479-1490
-
-
Graham, M.J.1
Lee, R.G.2
Bell III, T.A.3
-
63
-
-
84863984123
-
Gene therapy for lipoprotein lipase deficiency
-
Gaudet D, Methot J, Kastelein J. Gene therapy for lipoprotein lipase deficiency. Curr. Opin. Lipidol. 23(4), 310-320 (2012
-
(2012)
Curr. Opin. Lipidol
, vol.23
, Issue.4
, pp. 310-320
-
-
Gaudet, D.1
Methot, J.2
Kastelein, J.3
-
64
-
-
84880133265
-
Microsomal transfer protein inhibition in humans
-
Cuchel M, Rader DJ. Microsomal transfer protein inhibition in humans. Curr. Opin. Lipidol. 24(3), 246-250 (2013
-
(2013)
Curr. Opin. Lipidol
, vol.24
, Issue.3
, pp. 246-250
-
-
Cuchel, M.1
Rader, D.J.2
-
65
-
-
77956230636
-
Plasma PCSK9 is increased by fenofibrate and atorvastatin in a non-Additive fashion in diabetic patients
-
Costet P, Hoffmann MM, Cariou B, Guyomarch DB, Konrad T, Winkler K. Plasma PCSK9 is increased by fenofibrate and atorvastatin in a non-Additive fashion in diabetic patients. Atherosclerosis 212(1), 246-251 (2010
-
(2010)
Atherosclerosis
, vol.212
, Issue.1
, pp. 246-251
-
-
Costet, P.1
Hoffmann, M.M.2
Cariou, B.3
Guyomarch, D.B.4
Konrad, T.5
Winkler, K.6
-
66
-
-
84868689211
-
Atorvastatin with or without an antibody to PCSK9 in primary hypercholesterolemia
-
Roth EM, McKenney JM, Hanotin C, Asset G, Stein EA. Atorvastatin with or without an antibody to PCSK9 in primary hypercholesterolemia. N. Engl. J. Med. 367(20), 1891-1900 (2012
-
(2012)
N. Engl. J. Med
, vol.367
, Issue.20
, pp. 1891-1900
-
-
Roth, E.M.1
McKenney, J.M.2
Hanotin, C.3
Asset, G.4
Stein, E.A.5
-
67
-
-
84870478439
-
Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 in combination with a statin in patients with hypercholesterolaemia (laplace-Timi 57): A randomised, placebo-controlled, dose-ranging, phase 2 study
-
Giugliano RP, Desai NR, Kohli P et al. Efficacy, safety, and tolerability of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 in combination with a statin in patients with hypercholesterolaemia (LAPLACE-TIMI 57): A randomised, placebo-controlled, dose-ranging, phase 2 study. Lancet 380(9858), 2007-2017 (2012
-
(2012)
Lancet
, vol.380
, Issue.9858
, pp. 2007-2017
-
-
Giugliano, R.P.1
Desai, N.R.2
Kohli, P.3
-
68
-
-
84871780432
-
Lipids antibodies against pcsk9-A new era of therapy
-
King A. Lipids. Antibodies against PCSK9-A new era of therapy. Nat. Rev. Cardiol. 10(1), 1 (2013
-
(2013)
Nat. Rev. Cardiol
, vol.10
, Issue.1
, pp. 1
-
-
King, A.1
-
69
-
-
84880095092
-
Pcsk9 inhibitors
-
Farnier M. PCSK9 inhibitors. Curr. Opin. Lipidol. 24(3), 251-258 (2013
-
(2013)
Curr. Opin. Lipidol
, vol.24
, Issue.3
, pp. 251-258
-
-
Farnier, M.1
-
70
-
-
84873927641
-
Anti-pcsk9 therapies for the treatment of hypercholesterolemia
-
Hooper AJ, Burnett Jr. Anti-PCSK9 therapies for the treatment of hypercholesterolemia. Expert Opin. Biol. Ther. 13(3), 429-435 (2013
-
(2013)
Expert Opin. Biol. Ther
, vol.13
, Issue.3
, pp. 429-435
-
-
Hooper, A.J.1
Burnett, J.R.2
-
71
-
-
78651350647
-
Pcsk9: An emerging target for treatment of hypercholesterolemia
-
Duff CJ, Hooper NM. PCSK9: An emerging target for treatment of hypercholesterolemia. Expert Opin. Ther. Targets 15(2), 157-168 (2011
-
(2011)
Expert Opin. Ther. Targets
, vol.15
, Issue.2
, pp. 157-168
-
-
Duff, C.J.1
Hooper, N.M.2
-
72
-
-
84863582389
-
Antisense oligonucleotides for the treatment of dyslipidaemia
-
Visser ME, Witztum JL, Stroes ES, Kastelein JJ. Antisense oligonucleotides for the treatment of dyslipidaemia. Eur. Heart J. 33(12), 1451-1458 (2012
-
(2012)
Eur. Heart J.
, vol.33
, Issue.12
, pp. 1451-1458
-
-
Visser, M.E.1
Witztum, J.L.2
Stroes, E.S.3
Kastelein, J.J.4
-
73
-
-
84856517940
-
Pcsk9 lna antisense oligonucleotides induce sustained reduction of ldl cholesterol in nonhuman primates
-
Lindholm MW, Elmen J, Fisker N et al. PCSK9 LNA antisense oligonucleotides induce sustained reduction of LDL cholesterol in nonhuman primates. Mol. Ther. 20(2), 376-381 (2012
-
(2012)
Mol. Ther
, vol.20
, Issue.2
, pp. 376-381
-
-
Lindholm, M.W.1
Elmen, J.2
Fisker, N.3
-
74
-
-
77956519356
-
A locked nucleic acid antisense oligonucleotide (lna) silences pcsk9 and enhances ldlr expression in vitro and in vivo
-
Gupta N, Fisker N, Asselin MC et al. A locked nucleic acid antisense oligonucleotide (LNA) silences PCSK9 and enhances LDLR expression in vitro and in vivo. PLoS ONE 5(5), e10682 (2010
-
(2010)
PLoS ONE
, vol.5
, Issue.5
-
-
Gupta, N.1
Fisker, N.2
Asselin, M.C.3
-
75
-
-
50149101511
-
Therapeutic rnai targeting pcsk9 acutely lowers plasma cholesterol in rodents and ldl cholesterol in nonhuman primates
-
Frank-Kamenetsky M, Grefhorst A, Anderson NN et al. Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates. Proc. Natl Acad. Sci. USA 105(33), 11915-11920 (2008
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, Issue.33
, pp. 11915-11920
-
-
Frank-Kamenetsky, M.1
Grefhorst, A.2
Anderson, N.N.3
-
76
-
-
79960010914
-
An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells
-
Daquinag AC, Zhang Y, Amaya-Manzanares F, Simmons PJ, Kolonin MG. An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells. Cell Stem Cell. 9(1), 74-86 (2011
-
(2011)
Cell Stem Cell
, vol.9
, Issue.1
, pp. 74-86
-
-
Daquinag, A.C.1
Zhang, Y.2
Amaya-Manzanares, F.3
Simmons, P.J.4
Kolonin, M.G.5
-
77
-
-
38949171001
-
Impact of triglyceride levels beyond low-density lipoprotein cholesterol after acute coronary syndrome in the prove it-Timi 22 trial
-
Miller M, Cannon CP, Murphy SA, Qin J, Ray KK, Braunwald E. Impact of triglyceride levels beyond low-density lipoprotein cholesterol after acute coronary syndrome in the PROVE IT-TIMI 22 trial. J. Am.Coll.Cardiol. 51(7), 724-730 (2008
-
(2008)
J. Am.Coll.Cardiol
, vol.51
, Issue.7
, pp. 724-730
-
-
Miller, M.1
Cannon, C.P.2
Murphy, S.A.3
Qin, J.4
Ray, K.K.5
Braunwald, E.6
-
78
-
-
33846637379
-
Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies
-
Sarwar N, Danesh J, Eiriksdottir G et al. Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies. Circulation 115(4), 450-458 (2007
-
(2007)
Circulation
, vol.115
, Issue.4
, pp. 450-458
-
-
Sarwar, N.1
Danesh, J.2
Eiriksdottir, G.3
|