Decreased apolipoprotein A5 is implicated in insulin resistance-related hypertriglyceridemia in obesity

Atherosclerosis

Volumn 210, Issue 2, 2010, Pages 563-568

  Huang, Xian sheng ^a   Zhao, Shui Ping ^a   Hu, Min ^a   Bai, Lin ^a   Zhang, Qian ^a   Zhao, Wang ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Apolipoprotein A5; Inflammation; Insulin resistance; Obesity; Triglyceride

Indexed keywords

APOLIPOPROTEIN A5; DNA; FRUCTOSE; GUANINE; INSULIN; THYMINE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY MASS; CELL STRAIN HEPG2; CONTROLLED STUDY; DIETARY INTAKE; DNA CONTENT; FEMALE; HOMEOSTASIS; HUMAN; HUMAN CELL; HYPERTRIGLYCERIDEMIA; IN VITRO STUDY; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT;

ADULT; ANIMALS; APOLIPOPROTEINS; APOLIPOPROTEINS A; FEMALE; GLUCOSE CLAMP TECHNIQUE; HUMANS; HYPERTRIGLYCERIDEMIA; INSULIN; INSULIN RESISTANCE; MALE; MIDDLE AGED; OBESITY; RATS; RATS, ZUCKER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77953231023     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.12.004     Document Type: Article

References (34)

1. Fantuzzi G., Mazzone T. Adipose tissue and atherosclerosis: exploring the connection. Arterioscler Thromb Vasc Biol 2007, 27:996-1003.
2. Van Gaal L.F., Mertens I.L., De Block C.E. Mechanisms linking obesity with cardiovascular disease. Nature 2006, 444:875-880.
3. Pennacchio L.A., Olivier M., Hubacek J.A., et al. An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing. Science 2001, 294:169-173.
4. Priore Oliva C., Pisciotta L., Li Volti G., et al. Inherited apolipoprotein A-V deficiency in severe hypertriglyceridemia. Arterioscler Thromb Vasc Biol 2005, 25:411-417.
5. Dallinga-Thie G.M., van Tol A., Hattori H., et al. Plasma apolipoprotein A5 and triglycerides in type 2 diabetes. Diabetologia 2006, 49:1505-1511.
6. Dorfmeister B., Brandlhofer S., Schaap F.G., et al. Apolipoprotein AV does not contribute to hypertriglyceridaemia or triglyceride lowering by dietary fish oil and rosiglitazone in obese Zucker rats. Diabetologia 2006, 49:1324-1332.
7. Hahne P., Krempler F., Schaap F.G., et al. Determinants of plasma apolipoprotein A-V and APOA5 gene transcripts in humans. J Intern Med 2008, 264:452-462.
8. Alborn W.E., Prince M.J., Konrad R.J. Relationship of apolipoprotein A5 and apolipoprotein C3 levels to serum triglycerides in patients with type 2 diabetes. Clin Chim Acta 2007, 378:154-158.
9. Schaap F.G., Nierman M.C., Berbée J.F., et al. Evidence for a complex relationship between apoA-V and apoC-III in patients with severe hypertriglyceridemia. J Lipid Res 2006, 47:2333-2339.
10. Henneman P., Schaap F.G., Havekes L.M., et al. Plasma apoAV levels are markedly elevated in severe hypertriglyceridemia and positively correlated with the APOA5 S19W polymorphism. Atherosclerosis 2007, 193:129-134.
11. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser 2000; 894:1-253.
12. Wat N.M., Lam T.H., Janus E.D., et al. Central obesity predicts the worsening of glycemia in southern Chinese. Int J Obes Relat Metab Disord 2001, 25:1789-1793.
13. Tan K.C., Wat N.M., Tam S.C., et al. C-reactive protein predicts the deterioration of glycemia in Chinese subjects with impaired glucose tolerance. Diabetes Care 2003, 26:2323-2328.
14. Zhao S.P., Hu S., Li J., et al. Association of human serum apolipoprotein A5 with lipid profiles affected by gender. Clin Chim Acta 2007, 376:68-71.
15. Huang X.S., Zhao S.P., Zhang Q., et al. Association of plasma apoA5 with lipid profiles in patients with acute coronary syndrome. Atherosclerosis 2009, 204:e99-102.
16. Ishihara M., Kujiraoka T., Iwasaki T., et al. A sandwich enzyme-linked immunosorbent assay for human plasma apolipoprotein A-V concentration. J Lipid Res 2005, 46:2015-2022.
17. Henneman P., Schaap F.G., Havekes L.M., et al. Plasma apoA5 levels are markedly elevated in severe hypertriglyceridemia and positively correlated with the APOA5 S19W polymorphism. Atherosclerosis 2007, 193:129-134.
18. D'Angelo G., Elmarakby A.A., Pollock D.M., et al. Fructose feeding increases insulin resistance but not blood pressure in Sprague-Dawley rats. Hypertension 2005, 46:806-811.
19. Xie W., Wang W., Su H., et al. leaves on insulin sensitivity in rats and HepG2. Comp Biochem Physiol C Toxicol Pharmacol 2006, 143:429-435.
20. Zhang H.J., Ji B.P., Chen G., et al. A combination of grape seed-derived procyanidins and gypenosides alleviates insulin resistance in mice and HepG2 cells. J Food Sci 2009, 74:H1-H7.
21. Carr T.P., Andresen C.J., Rudel L.L. Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts. Clin Biochem 1993, 26:39-42.
22. Gupta D., Varma S., Khandelwal R.L. Long-term effects of tumor necrosis factor-alpha treatment on insulin signaling pathway in HepG2 cells and HepG2 cells overexpressing constitutively active Akt/PKB. J Cell Biochem 2007, 100:593-607.
23. Siri P., Candella N., Ko C., et al. Post-transcriptional stimulation of the assembly and secretion of triglyceride-rich apolipoprotein B-lipoproteins in a mouse with selective deficiency of brown adipose tissue, obesity, and insulin resistance. J Biol Chem 2001, 276:46064-46072.
24. Yu Y.-H., Ginsberg H.N. Adipocyte signaling and lipid homeostasis: sequelae of insulin-resistant adipose tissue. Circ Res. 2005, 96:1042-1052.
25. Miyashita Y., Shirai K., Itoh Y., et al. Low lipoprotein lipase mass in preheparin serum of type 2 diabetes mellitus patients and its recovery with insulin therapy. Diabetes Res Clin Pract 2002, 56:181-187.
26. Phillips M.S., Liu Q., Hammond H.A., et al. Leptin receptor missense mutation in the fatty Zucker rat. Nat Genet 1996, 13:18-19.
27. Grarup N., Andersen G. Gene-environment interactions in the pathogenesis of type 2 diabetes and metabolism. Curr Opin Clin Nutr Metab Care 2007, 10:420-426.
28. Ordovas J.M., Tai E.S. Why study gene-environment interactions?. Curr Opin Lipidol 2008, 19:158-167.
29. Nowak M., Helleboid-Chapman A., Jakel H., et al. Insulin-mediated down-regulation of apolipoprotein A5 gene expression through the phosphatidylinositol 3-kinase pathway: role of upstream stimulatory factor. Mol Cell Biol 2005, 25:1537-1548.
30. Hotamisligil G.S., Spiegelman B.M. Tumor necrosis factor alpha: a key component of the obesity-diabetes link. Diabetes 1994, 43:1271-1278.
31. Heliövaara M.K., Teppo A.M., Karonen S.L., et al. Inflammation affects lipid metabolism during recovery from hyperinsulinaemia. Eur J Clin Invest 2006, 36:860-865.
32. Yu Y.-H., Ginsberg H.N. Adipocyte signaling and lipid homeostasis: sequelae of insulin-resistant adipose tissue. Circ Res 2005, 96:1042-1052.
33. Genoux A., Gervois P., Vu-Dac N., et al. Apolipoprotein A5 is an inflammatory responsive gene down-regulated by tumor necrosis factor alpha and interleukin-1. Atherosclerosis 2003, 241. Suppl 4.
34. Khovidhunkit W., Duchateau P.N., Medzihradszky K.F., et al. Apolipoproteins A-IV and A-V are acute-phase proteins in mouse HDL. Atherosclerosis 2004, 176:37-44.