Non-physician clinician provided HIV treatment results in equivalent outcomes as physician-provided care: A meta-analysis

Journal of the International AIDS Society

Volumn 16, Issue , 2013, Pages

  Emdin, Connor A ^a   Chong, Nicholas J ^a   Millson, Peggy E ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Antiretroviral therapy; ART; HIV treatment; Non physician; Substitution of physicians; Task shifting

Indexed keywords

ANTIVIRUS AGENT; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ANTIRETROVIRAL THERAPY; ANTIVIRAL THERAPY; FOLLOW UP; HEALTH CARE PERSONNEL; HEALTH CARE POLICY; HEALTH CARE QUALITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MANAGED CARE; META ANALYSIS; NURSE; PATIENT SATISFACTION; PHYSICIAN; PRIORITY JOURNAL; QUALITY CONTROL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SOUTH AFRICA; SYSTEMATIC REVIEW; TREATMENT OUTCOME; WEIGHT GAIN; AFRICA SOUTH OF THE SAHARA; ART; BODY WEIGHT; HIV TREATMENT; MEDICATION COMPLIANCE; NON-PHYSICIAN; PATHOLOGY; STATISTICS; SUBSTITUTION OF PHYSICIANS; SURVIVAL; TASK SHIFTING; TUBERCULOSIS;

ANTIRETROVIRAL THERAPY; ART; HIV TREATMENT; NON-PHYSICIAN; SUBSTITUTION OF PHYSICIANS; TASK SHIFTING;

AFRICA SOUTH OF THE SAHARA; ANTI-HIV AGENTS; BODY WEIGHT; HIV INFECTIONS; HUMANS; MEDICATION ADHERENCE; NURSES; PATIENT SATISFACTION; PHYSICIANS; SURVIVAL ANALYSIS; TREATMENT OUTCOME; TUBERCULOSIS;

EID: 84887288222     PISSN: None     EISSN: 17582652     Source Type: Journal    
DOI: 10.7448/IAS.16.1.18445     Document Type: Review

References (25)

1. Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365(6):493-505.
2. Maddison AR, Schlech WF. Will universal access to antiretroviral therapy ever be possible? The health care worker challenge. Can J Infect Dis Med Microbiol. 2010;21(1):64-9.
3. Callaghan M, Ford N, Schneider H. A systematic review of task shifting for HIV treatment and care in Africa. Hum Resour Health. 2010;8:8.
4. Colvin CJ, Fairall L, Lewin S, Georgeu D, Zwarenstein M, Bachmann MO, et al. Expanding access to ART in South Africa: the role of nurse-initiated treatment. S Afr Med J. 2010;100(4):210-2.
5. Emdin CA, Millson P. A systematic review evaluating the impact of task shifting on access to antiretroviral therapy in sub-Saharan Africa. Afr Health Sci. 2012;12(3):318-24.
6. Price J, Binagwaho A. From medical rationing to rationalizing the use of human resources for AIDS care and treatment in Africa: a case for task shifting. Develop World Bioeth. 2010;10(2):99-103.
7. Parmar MK, Torri V, Stewart L. Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Stat Med. 1998;17(24):2815-34.
8. Brennan AT, Long L, Maskew M, Sanne I, Jaffray I, MacPhail P, et al. Outcomes of stable HIV-positive patients down-referred from a doctor-managed antiretroviral therapy clinic to a nurse-managed primary health clinic for monitoring and treatment. AIDS. 2011;25(16):2027-36.
9. Sanne I, Orrell C, Fox MP, Conradie F, Ive P, Zeinecker J, et al. Nurse versus doctor management of HIV-infected patients receiving antiretroviral therapy (CIPRA-SA): a randomised non-inferiority trial. Lancet. 2010;376(9734):33-40.
10. Pienaar D, Myer L, Cleary S, Englebrecht M. Models of care for antiretroviral service delivery in three provinces of South Africa [Abstract]. 4th Public Health Association of South Africa Conference. Cape Town: University of Cape Town; 2008.
11. Humphreys CP, Wright J, Walley J, Mamvura CT, Bailey KA, Ntshalintshali SN, et al. Nurse led, primary care based antiretroviral treatment versus hospital care: a controlled prospective study in Swaziland. BMC Health Serv Res. 2010;10:229.
12. Labhardt N. Outcomes of antiretroviral treatment programs in rural Lesotho: health centers and hospitals compared [Abstract]. Washington, DC: AIDS; 2012.
13. Bedelu M, Ford N, Hilderbrand K, Reuter H. Implementing antiretroviral therapy in rural communities: the Lusikisiki model of decentralized HIV/AIDS care. J Infect Dis. 2007;196(Suppl 3):464-8.
14. Fairall L, Bachmann M, Lombard C, Timmerman V, Uebel K, Zwarenstein M, et al. Task shifting of antiretroviral treatment from doctors to primary-care nurses in South Africa (STRETCH): a pragmatic, parallel, cluster-randomised trial. Lancet. 2012;380(9845):889-98.
15. Assefa Y, Kiflie A, Tekle B, Mariam DH, Laga M, Van Damme W. Effectiveness and acceptability of delivery of antiretroviral treatment in health centres by health officers and nurses in Ethiopia. J Health Serv Res Pol. 2012;17(1):24-9.
16. Sherr KH, Micek MA, Gimbel SO, Gloyd SS, Hughes JP, John-Stewart GC, et al. Quality of HIV care provided by non-physician clinicians and physicians in Mozambique: a retrospective cohort study. AIDS. 2010;24(Suppl 1):59-66.
17. Monyatsi G, Mullan PC, Phelps BR, Tolle MA, Machine EM, Gennari FF, et al. HIV management by nurse prescribers compared with doctors at a paediatric centre in Gaborone, Botswana. S Afr Med J. 2012;102(1):34-7.
18. Boyer S, Clerc I, Bonono CR, Marcellin F, Bile PC, Ventelou B. Non-adherence to antiretroviral treatment and unplanned treatment interruption among people living with HIV/AIDS in Cameroon: individual and healthcare supply-related factors. Soc Sci Med. 2011;72(8):1383-92.
19. Vasan A, Kenya-Mugisha N, Seung KJ, Achieng M, Banura P, Lule F, et al. Agreement between physicians and non-physician clinicians in starting antiretroviral therapy in rural Uganda. Hum Resour Health. 2009;7:75.
20. Shumbusho F, van Griensven J, Lowrance D, Turate I, Weaver MA, Price J, et al. Task shifting for scale-up of HIV care: evaluation of nurse-centered antiretroviral treatment at rural health centers in Rwanda. PLoS Med. 2009;6(10):e1000163.
21. Bolton-Moore C, Mubiana-Mbewe M, Cantrell RA, Chintu N, Stringer EM, Chi BH, et al. Clinical outcomes and CD4 cell response in children receiving antiretroviral therapy at primary health care facilities in Zambia. J Am M A. 2007;298(16):1888-99.
22. Drummond M. Methods for the economic evaluation of health care programmes. 3rd ed. Oxford: Oxford University Press; 2005.
23. Ford N, Calmy A, Mills EJ. The first decade of antiretroviral therapy in Africa. Global Health. 2011;7:33.
24. Medicines Sans Frontieres. Speed up scale-up: strategies, tools and policies to get the best HIV treatment to more people, sooner. Medicines Sans Frontieres; 2012. Available from: http://www.msf.org/sites/msf.org/files/old- cms/fms/article-documents/MSF-Speed-up-Scale-up-report-webres.pdf
25. Long L, Brennan A, Fox MP, Ndibongo B, Jaffray I, Sanne I, et al. Treatment outcomes and cost-effectiveness of shifting management of stable ART patients to nurses in South Africa: an observational cohort. PLoS Med. 2011;8(7):e1001055.