Exosomes: The novel vehicles for intercellular communication

Progress in Biochemistry and Biophysics

Volumn 40, Issue 8, 2013, Pages 719-727

  Liu, Ru Tao ^a   Wang, Shi Wei ^a   Liu, Jing ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Exosomes; Gene therapy; Intercellular communication; Neural system; Stem cells

Indexed keywords

EID: 84887260919     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2012.00578     Document Type: Review

References (44)

1. Lasser C, Seyed Alikhani V, Ekstrom K, et al. Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. J Translational Medicine, 2011, 9: 9
2. Valadi H, Ekström K, Bossios A, et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol, 2007, 9(6): 654-659 (Pubitemid 47214727)
3. Alvarez-Erviti L, Seow Y, Yin H, et al. Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes. Nat Biotechnol, 2011, 29(4): 341-345
4. Pan B T, Teng K, Wu C, et al. Electron microscopic evidence for externalization of the transferring receptor in vesicular form in sheep reticulocytes. J Cell Biol, 1985, 101(3): 942-948 (Pubitemid 16256847)
5. Clayton A, Harris C L, Court J, et al. Antigen- presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59. European J Immunology, 2003, 33(2): 522-531 (Pubitemid 36267618)
6. Mathivanan S, Simpson R J. ExoCarta: a compendium of exosomal proteins and RNA. Proteomics, 2009, 9(21): 4997-5000
7. Mathivanan S, Fahner C J, Reid G E, et al. ExoCarta 2012: database of exosomal proteins, RNA and lipids. Nucl Acid Res, 2012, 40(D1): D1241-D1244
8. Simon M, Raposo G. Exosomes-vesicular carriers for intercellular communication. Current Opinion in Cell Biology, 2009, 21 (4): 575-581
9. Skoq J, Wurdinger T, van Rijn S, et al. Glioblastoma microvesicles transport RNA and protein that promote tumor growth and provide diagnostic biomarkers. Nat Cell Biol, 2008, 10(12): 1470-1476
10. Zhou Q, Li M Z, Wang X Y, et al. Immune-related microRNAs are abundant in breast milk exosomes. Int J Biol Sci, 2012, 8(1): 118-123
11. Bian S, Sun T. Functions of noncoding RNAs in neural development and neurological diseases. Mol Neurobiol, 2011, 44(3): 359-373
12. Chen T S, Arslan F, Yin Y J, et al. Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs. J Translational Medicine, 2011, 9: 47
13. Théry C, Amigorena S, Raposo G, et al. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol, 2006, 3: 22
14. Jodo S, Xiao S, Hohlbaum A, et al. Apoptosis- inducing Membrane Vesicles: a novel agent with unique properties. J Biol Chem, 2001, 276(43): 39938-39944
15. Raposo G, Nijman HW, Stoorvogel W, et al. B lymphocytes secrete antigen-presenting vesicles. J Exp Med, 1996, 183(3): 1161-1172 (Pubitemid 26113979)
16. Gross J C, Chaudhary V, Bartscherer K, et al. Active Wnt proteins are secreted on exosomes. Nat Cell Biol, 2012, 14(10): 1036-1045
17. Montecalvo A, Larregina A T, Shufesky W J, et al. Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes. Blood, 2012, 119(3): 756-766
18. Taylor D D, Gercel-Taylor C. Exosomes/microvesicles: mediators of cancer-associated immunosuppressive microenvironments. Semin Immunopathol, 2011, 33(5): 441-454
19. Hergenreider E, Heydt S, Tréguer K, et al. Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol, 2012, 14(3): 249-256
20. Müller G, Schneider M, Biemer-Daub G, et al. Microvesicles released from rat adipocytes and harboring glycosylphosphatidylinositol-anchored proteins transfer RNA stimulating lipid synthesis. Cell Signal, 2011, 23(7): 1207-1223
21. Chen T S, Lai R C, Lee M M, et al. Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs. Nucleic Acids Res, 2010, 38(1): 215-224
22. Lai R C, Arslan F, Lee M M, et al. Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury. Stem Cell Res, 2010, 4(3): 214-222
23. Xin H, Li Y, Buller B, et al. Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowth. Stem Cells, 2012, 30(7): 1556-1564
24. Looze C, Yui D, Leung L, et al. Proteomic profiling of human plasma exosomes identifies PPARγ as an exosome-associated protein. Biochem Biophys Res Commun, 2009, 378(3): 433-438
25. Beloribi S, Ristorcelli E, Breuzard G, et al. Exosomal lipids impact notch signaling and induce death of human pancreatic tumoral SOJ-6 cells. PLoS One, 2012, 7(10): e47480
26. Wang S, Cesca F, Loers G, et al. Synapsin I is an oligomannose-canying glycoprotein, acts as an oligomannose- binding lectin, and promotes neunte outgrowth and neuronal survival when released via glia-derived exosomes. J Neuroscience, 2011, 31(20): 7275-7290
27. Bakhti M, Winter C, Simons M, et al. Inhibition of myelin membrane sheath formation by oligodendrocyte-derived exosome-like vesicles. J Biol Chem, 2011, 286(1): 787-796
28. Twiss J L, Fainzilber M. Ribosomes in axons-scrounging from the neighbors?. Trends Cell Biol, 2009, 19(5): 236-243
29. Coleman B M, Hanssen E, Lawson V A, et al. Prion-infected cells regulate the release of exosomes with distinct ultrastructural features. FASEB J, 2012, 26(10): 4160-4173
30. Alvarez-Erviti L, Seow Y, Schapira A H, et al. Lysosomal dysfunction increases exosome-mediated alpha- synuclein release and transmission. Neurobiology of Disease, 2011, 42(3): 360-367
31. Sharples R A, Vella L J, Nisbet R M, et al. Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes. FASEB J, 2008, 22(5): 1469-1478 (Pubitemid 351656787)
32. Liu J, He Q J, Zou W, et al. Catalpol increases hippocampal neuroplasticity and up-regulates PKC and BDNF in the aged rats. Brain Research, 2006, 1123(1): 68-79
33. Zhang H G, Grizzle W E. Exosomes and cancer: a newly described pathway of immune suppression. Clin Cancer Res, 2011, 17(5): 959-964
34. Webber J, Steadman R, Mason M D, et al. Cancer exosomes trigger fibroblast to myofibroblast differentiation. Cancer Res, 2010, 70(23): 9621-9630
35. Hong B S, Cho J H, Choi E J, et al. Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells. BMC Genomics, 2009, 10: 556
36. Gutwein P, Stoeck A, Riedle S, et al. Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells. Clin Cancer Res, 2005, 11(7): 2492-2501 (Pubitemid 40569445)
37. Khan S, Aspe J R, Asumen M G, et al. Extracellular cell-permeable survivin inhibits apoptosis while promoting proliferative and metastatic potential. Br J Cancer, 2009, 100(7): 1073-1086
38. Mathivanan S, Lim J W, Tauro B J, et al. Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature. Mol Cell Proteomics, 2010, 9(2): 197-208
39. Miranda K C, Bond D T, McKee Mary, et al. Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease. Kidney Int, 2010, 78(2): 191-199
40. Mitchell P S, Parkin R K, Kroh E M, et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci USA, 2008, 105(30): 10513-10518
41. Bianco N R, Kim S H, Ruffher M A, et al. Therapeutic effect of exosomes from indoleamine 2, 3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models. Arthritis Rheum, 2009, 60(2): 380-389
42. Yang X, Meng S, Jiang H, et al. Exosomes derived from interleukin-10-treated dendritic cells can inhibit trinitrobenzene sulfonic acid-induced rat colitis. Scand J Gastroenterol, 2010, 45(10): 1168-1177
43. Sahoo S, Klychko E, Thorne T, et al. Exosomes from human CD34 + stem cells mediate their proangiogenic paracrine activity. Circ Res, 2011, 109(7): 724-728
44. van den Boom J G, Schlee M, Coch C, et al. siRNA delivery with exosome nanoparticles. Nat Biotechnol, 2011, 29(4): 325-326