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Volumn , Issue , 2013, Pages 199-223

Polymeric Drug Delivery Systems for Encapsulating Hydrophobic Drugs

Author keywords

Emulsion polymerization; In situ polymerization; Interfacial condensation; Interfacial polymerization; Miniemulsion; Nanocapsules; Nanospheres; Radical polymerization; Tank reactors

Indexed keywords


EID: 84887251816     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781118444726.ch6     Document Type: Chapter
Times cited : (5)

References (105)
  • 1
    • 80054794155 scopus 로고    scopus 로고
    • Drug delivery strategies for poorly water-soluble drugs: the industrial perspective
    • P. van Hoogevest, X. Liu, A. Fahr, Drug delivery strategies for poorly water-soluble drugs: the industrial perspective. Expert Opinion on Drug Delivery, 8(11), 1481-1500 (2011).
    • (2011) Expert Opinion on Drug Delivery , vol.8 , Issue.11 , pp. 1481-1500
    • van Hoogevest, P.1    Liu, X.2    Fahr, A.3
  • 2
    • 41949100244 scopus 로고    scopus 로고
    • Drug nanoparticles: Formulating poorly water-soluble compounds
    • E.M.G. Merisko-Liversidge, G. Liversidge, Drug nanoparticles: Formulating poorly water-soluble compounds. Toxicologic Pathology, 36(1), 43-48 (2008).
    • (2008) Toxicologic Pathology , vol.36 , Issue.1 , pp. 43-48
    • Merisko-Liversidge, E.M.G.1    Liversidge, G.2
  • 4
    • 79952290746 scopus 로고    scopus 로고
    • Polymers in drug delivery: State of the art and future trends
    • S. Grund, M. Bauer, D. Fischer, Polymers in drug delivery: State of the art and future trends. Advanced Engineering Materials, 13(3), B61-B87 (2011).
    • (2011) Advanced Engineering Materials , vol.13 , Issue.3
    • Grund, S.1    Bauer, M.2    Fischer, D.3
  • 5
    • 1642362625 scopus 로고    scopus 로고
    • Drug delivery systems: Entering the mainstream
    • T.M. Allen, P.R. Cullis, Drug delivery systems: Entering the mainstream. Science, 303(5665), 1818-1822 (2004).
    • (2004) Science , vol.303 , Issue.5665 , pp. 1818-1822
    • Allen, T.M.1    Cullis, P.R.2
  • 7
    • 56949102614 scopus 로고    scopus 로고
    • The origins and evolution of 'controlled' drug delivery systems
    • A.S. Hoffman, The origins and evolution of 'controlled' drug delivery systems. Journal of Controlled Release, 132(3), 153-163 (2008).
    • (2008) Journal of Controlled Release , vol.132 , Issue.3 , pp. 153-163
    • Hoffman, A.S.1
  • 8
    • 70349257014 scopus 로고    scopus 로고
    • Polymeric nanocarriers: New endeavors for the optimization of the technological aspects of drugs
    • A. Sosnik, A.M. Carcaboso, D.A. Chiappetta, Polymeric nanocarriers: New endeavors for the optimization of the technological aspects of drugs. Recent Patents on Biomedical Engineering, 1(1), 43-59 (2008).
    • (2008) Recent Patents on Biomedical Engineering , vol.1 , Issue.1 , pp. 43-59
    • Sosnik, A.1    Carcaboso, A.M.2    Chiappetta, D.A.3
  • 9
    • 77950500442 scopus 로고    scopus 로고
    • Drug delivery systems: Advanced technologies potentially applicable in personalized treatments
    • J. Coelho, et al., Drug delivery systems: Advanced technologies potentially applicable in personalized treatments. The EPMA Journal, 1(1), 164-209 (2010).
    • (2010) The EPMA Journal , vol.1 , Issue.1 , pp. 164-209
    • Coelho, J.1
  • 10
    • 33645034817 scopus 로고    scopus 로고
    • Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles. Nanomedicine: Nanotechnology
    • C. Pinto Reis, et al., Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine, 2(1), 8-21 (2006).
    • (2006) Biology and Medicine , vol.2 , Issue.1 , pp. 8-21
    • Pinto Reis, C.1
  • 11
    • 84887256651 scopus 로고
    • Controlled Drug Delivery with Nanoparticles: Current Possibilities and Future Trends
    • Amsterdam: Elsevier
    • P. Couvreur, C. Dubernet, F. Puisieux, Controlled Drug Delivery with Nanoparticles: Current Possibilities and Future Trends. Vol. 41. Amsterdam: Elsevier (1995).
    • (1995)
    • Couvreur, P.1    Dubernet, C.2    Puisieux, F.3
  • 12
    • 63949086707 scopus 로고    scopus 로고
    • Methods for the preparation and manufacture of polymeric nanoparticles
    • C.Vauthier, K. Bouchemal, Methods for the preparation and manufacture of polymeric nanoparticles. Pharm Res, 26(5), 1025-1058 (2009).
    • (2009) Pharm Res , vol.26 , Issue.5 , pp. 1025-1058
    • Vauthier, C.1    Bouchemal, K.2
  • 13
    • 64249109799 scopus 로고    scopus 로고
    • Principles and Applications of Emulsion Polymerization
    • New York: Wiley
    • C.S. Chern, Principles and Applications of Emulsion Polymerization. New York: Wiley (2008).
    • (2008)
    • Chern, C.S.1
  • 14
    • 33646703123 scopus 로고    scopus 로고
    • Emulsion polymerization mechanisms and kinetics
    • C.S. Chern, Emulsion polymerization mechanisms and kinetics. Progress in Polymer Science, 31(5), 443-486 (2006).
    • (2006) Progress in Polymer Science , vol.31 , Issue.5 , pp. 443-486
    • Chern, C.S.1
  • 15
    • 0003419115 scopus 로고
    • Kinetics of emulsion polymerization Journal of Chemical Physics
    • W.V. Smith, R.H. Ewart, Kinetics of emulsion polymerization Journal of Chemical Physics, 16(6), 592-599 (1948).
    • (1948) , vol.16 , Issue.6 , pp. 592-599
    • Smith, W.V.1    Ewart, R.H.2
  • 16
    • 24344453328 scopus 로고
    • The kinetics of styrene emulsion polymerization
    • W.V. Smith, The kinetics of styrene emulsion polymerization. Journal of the American Chemical Society, 70(11), 3695-3702 (1948).
    • (1948) Journal of the American Chemical Society , vol.70 , Issue.11 , pp. 3695-3702
    • Smith, W.V.1
  • 17
    • 0001068613 scopus 로고
    • Chain initiation in styrene emulsion polymerization
    • W.V. Smith, Chain initiation in styrene emulsion polymerization. Journal of the American Chemical Society, 71(12), 4077-4082 (1949).
    • (1949) Journal of the American Chemical Society , vol.71 , Issue.12 , pp. 4077-4082
    • Smith, W.V.1
  • 18
    • 24044476537 scopus 로고
    • A general theory of the mechanism of emulsion polymerization
    • W.D. Harkins, A general theory of the mechanism of emulsion polymerization. Journal of the American Chemical Society, 69(6), 1428-1444 (1947).
    • (1947) Journal of the American Chemical Society , vol.69 , Issue.6 , pp. 1428-1444
    • Harkins, W.D.1
  • 19
    • 0000891052 scopus 로고
    • Emulsion polymerization. I. Recalculation and extension of the Smith-Ewart theory
    • J.L. Gardon, Emulsion polymerization. I. Recalculation and extension of the Smith-Ewart theory. Journal of Polymer Science Part A-1: Polymer Chemistry, 6(3), 623-641 (1968).
    • (1968) Journal of Polymer Science Part A-1: Polymer Chemistry , vol.6 , Issue.3 , pp. 623-641
    • Gardon, J.L.1
  • 20
    • 0000891053 scopus 로고
    • Emulsion polymerization. II. Review of experimental data in the context of the revised Smith-Ewart theory
    • J.L. Gardon, Emulsion polymerization. II. Review of experimental data in the context of the revised Smith-Ewart theory. Journal of Polymer Science Part A-1: Polymer Chemistry, 6(3), 643-664 (1968).
    • (1968) Journal of Polymer Science Part A-1: Polymer Chemistry , vol.6 , Issue.3 , pp. 643-664
    • Gardon, J.L.1
  • 21
    • 0026900934 scopus 로고
    • Suspension, emulsion, and dispersion polymerization: A methodological survey
    • R. Arshady, Suspension, emulsion, and dispersion polymerization: A methodological survey. Colloid & Polymer Science, 270(8), 717-732 (1992).
    • (1992) Colloid & Polymer Science , vol.270 , Issue.8 , pp. 717-732
    • Arshady, R.1
  • 22
    • 1542364285 scopus 로고    scopus 로고
    • Emulsion polymerization: From fundamental mechanisms to process developments
    • J.M. Asua, Emulsion polymerization: From fundamental mechanisms to process developments. Journal of Polymer Science Part A: Polymer Chemistry, 42(5), 1025-1041 (2004).
    • (2004) Journal of Polymer Science Part A: Polymer Chemistry , vol.42 , Issue.5 , pp. 1025-1041
    • Asua, J.M.1
  • 23
    • 0036205158 scopus 로고    scopus 로고
    • Nanoparticle technology for drug delivery across the blood-brain barrier
    • P.R. Lockman, et al., Nanoparticle technology for drug delivery across the blood-brain barrier. Drug Development and Industrial Pharmacy, 28(1), 1-13 (2002).
    • (2002) Drug Development and Industrial Pharmacy , vol.28 , Issue.1 , pp. 1-13
    • Lockman, P.R.1
  • 24
    • 0003495893 scopus 로고    scopus 로고
    • Principles of Polymerization
    • New York: Wiley
    • G. Odian, Principles of Polymerization. New York: Wiley (2004).
    • (2004)
    • Odian, G.1
  • 26
    • 0035575938 scopus 로고    scopus 로고
    • Controlled/living radical polymerization in aqueous media: Homogeneous and heterogeneous systems
    • J. Qiu, B. Charleux, K. Matyjaszewski, Controlled/living radical polymerization in aqueous media: Homogeneous and heterogeneous systems. Progress in Polymer Science, 26(10), 2083-2134 (2001).
    • (2001) Progress in Polymer Science , vol.26 , Issue.10 , pp. 2083-2134
    • Qiu, J.1    Charleux, B.2    Matyjaszewski, K.3
  • 27
    • 84878772620 scopus 로고    scopus 로고
    • Emulsion polymerisation and latex applications
    • Rapra Reviews Reports, Shropshire: iSmithers Publishing
    • C.D. Anderson, E.S. Daniels, Emulsion polymerisation and latex applications. Rapra Reviews Reports. Vol. 14., Shropshire: iSmithers Publishing (2003).
    • (2003)
    • Anderson, C.D.1    Daniels, E.S.2
  • 28
    • 63949086707 scopus 로고    scopus 로고
    • Methods for the preparation and manufacture of polymeric nanoparticles
    • C.Vauthier, K. Bouchemal, Methods for the preparation and manufacture of polymeric nanoparticles. Pharmaceutical Research, 26(5), 1025-1058 (2009).
    • (2009) Pharmaceutical Research , vol.26 , Issue.5 , pp. 1025-1058
    • Vauthier, C.1    Bouchemal, K.2
  • 29
    • 0002266635 scopus 로고
    • Particle formation in polymer colloids, III: Prediction of the number of particles by a homogeneous nucleation theroy
    • Polymer Colloids, ed. R.M. Fitch. New York: Plenum Press
    • R.M. Fitch, C.H. Tsai, Particle formation in polymer colloids, III: Prediction of the number of particles by a homogeneous nucleation theroy. Polymer Colloids, ed. R.M. Fitch. New York: Plenum Press (1971).
    • (1971)
    • Fitch, R.M.1    Tsai, C.H.2
  • 30
    • 0001076026 scopus 로고
    • A general theory of the reaction loci in emulsion polymerization
    • W.D. Harkins, A general theory of the reaction loci in emulsion polymerization Journal of Chemical Physics, 13(9), 381 (1945).
    • (1945) , vol.13 , Issue.9 , pp. 381
    • Harkins, W.D.1
  • 31
    • 0035062191 scopus 로고    scopus 로고
    • Radical polymerization in direct mini-emulsion systems
    • In New Polymerization Techniques and Synthetic Methodologies, Berlin: Springer Verlag
    • I. Capek, C.-S. Chern, Radical polymerization in direct mini-emulsion systems, In New Polymerization Techniques and Synthetic Methodologies, Berlin: Springer Verlag, pp. 101-165 (2001).
    • (2001) , pp. 101-165
    • Capek, I.1    Chern, C.-S.2
  • 32
    • 0142091421 scopus 로고    scopus 로고
    • Nonionic nanoparticles by miniemulsion polymerization of vinyl acetate with oligocaprolactone macromonomer or miglyol as hydrophobe application to the encapsulation of indomethacin
    • I. Rajot, et al., Nonionic nanoparticles by miniemulsion polymerization of vinyl acetate with oligocaprolactone macromonomer or miglyol as hydrophobe application to the encapsulation of indomethacin. Macromolecules, 36(20), 7484-7490 (2003).
    • (2003) Macromolecules , vol.36 , Issue.20 , pp. 7484-7490
    • Rajot, I.1
  • 33
    • 33749170937 scopus 로고    scopus 로고
    • Synthesis of colloidal particles in miniemulsions, in Annual Review of Materials Research
    • Palo Alto, CA: Annual Reviews
    • K. Landfester, Synthesis of colloidal particles in miniemulsions, in Annual Review of Materials Research. Palo Alto, CA: Annual Reviews, pp. 231-279 (2006).
    • (2006) , pp. 231-279
    • Landfester, K.1
  • 34
    • 84967496077 scopus 로고    scopus 로고
    • Nanoparticulates as Drug Carriers
    • London: Imperial College Press
    • V.P. Torchilin, Nanoparticulates as Drug Carriers. London: Imperial College Press (2006).
    • (2006)
    • Torchilin, V.P.1
  • 35
    • 0025744048 scopus 로고
    • Biodegradable nanospheres containing phthalocyanines and naphthalocyanines for targeted photodynamic tumor therapy
    • A. Labib, et al., Biodegradable nanospheres containing phthalocyanines and naphthalocyanines for targeted photodynamic tumor therapy. Pharmaceutical Research, 8(8), 1027-1031 (1991).
    • (1991) Pharmaceutical Research , vol.8 , Issue.8 , pp. 1027-1031
    • Labib, A.1
  • 36
    • 0035821412 scopus 로고    scopus 로고
    • Combined hydroxypropyl-beta-cyclodextrin and poly(alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir
    • H. Boudad, et al., Combined hydroxypropyl-beta-cyclodextrin and poly(alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir. International Journal of Pharmaceutics, 218(1-2), 113-124 (2001).
    • (2001) International Journal of Pharmaceutics , vol.218 , Issue.1-2 , pp. 113-124
    • Boudad, H.1
  • 37
    • 0141830659 scopus 로고    scopus 로고
    • Polymeric nano-and microparticles for the oral delivery of peptides and peptidomimetics
    • E. Allémann, J. Leroux, R. Gurny, Polymeric nano-and microparticles for the oral delivery of peptides and peptidomimetics. Advanced Drug Delivery Reviews, 34(2-3), 171-189 (1998).
    • (1998) Advanced Drug Delivery Reviews , vol.34 , Issue.2-3 , pp. 171-189
    • Allémann, E.1    Leroux, J.2    Gurny, R.3
  • 38
    • 0030131010 scopus 로고    scopus 로고
    • Preparation and characterization of polyethyl-2-cyanoacrylate nanocapsules containing antiepileptic drugs
    • M. Fresta, et al., Preparation and characterization of polyethyl-2-cyanoacrylate nanocapsules containing antiepileptic drugs. Biomaterials, 17(8), 751-758 (1996).
    • (1996) Biomaterials , vol.17 , Issue.8 , pp. 751-758
    • Fresta, M.1
  • 39
    • 0026501260 scopus 로고
    • Colloidal drug delivery systems for the eye:Acomparison of the efficacy of three different polymers: PolYisobutylcyanoacrylate, polylactic-coglycolic acid, polyepsilon-caprolacton
    • L. Marchal-Heussler, et al., Colloidal drug delivery systems for the eye:Acomparison of the efficacy of three different polymers: PolYisobutylcyanoacrylate, polylactic-coglycolic acid, polyepsilon-caprolacton. STP Pharma Sciences, 2, 98-104 (1992).
    • (1992) STP Pharma Sciences , vol.2 , pp. 98-104
    • Marchal-Heussler, L.1
  • 40
    • 0034303241 scopus 로고    scopus 로고
    • Pluronic R F127-based ocular delivery system containing biodegradable polyisobutylcyanoacrylate nanocapsules of pilocarpine
    • S.D. Desai, J. Blanchard, Pluronic R F127-based ocular delivery system containing biodegradable polyisobutylcyanoacrylate nanocapsules of pilocarpine. Drug Delivery, 7(4), 201-207 (2000).
    • (2000) Drug Delivery , vol.7 , Issue.4 , pp. 201-207
    • Desai, S.D.1    Blanchard, J.2
  • 41
    • 0024394894 scopus 로고
    • Evaluation of indomethacin nanocapsules for their physical stability and inhibitory activity on inflammation and platelet aggregation
    • A. Gürsoy, et al., Evaluation of indomethacin nanocapsules for their physical stability and inhibitory activity on inflammation and platelet aggregation. International Journal of Pharmaceutics, 52(2), 101-108 (1989).
    • (1989) International Journal of Pharmaceutics , vol.52 , Issue.2 , pp. 101-108
    • Gürsoy, A.1
  • 42
    • 0024950991 scopus 로고
    • Physicochemical characterization of polymeric nanocapsules and in vitro release evaluation of indomethacin as a model drug
    • N. Ammoury, et al., Physicochemical characterization of polymeric nanocapsules and in vitro release evaluation of indomethacin as a model drug. STP Pharma Sciences, 5, 642 (1989).
    • (1989) STP Pharma Sciences , vol.5 , pp. 642
    • Ammoury, N.1
  • 43
    • 0029745680 scopus 로고    scopus 로고
    • Ocular disposition of nanoencapsulated acyclovir and ganciclovir via intravitreal injection in rabbit's eye
    • M.S. El-Samaligy, et al., Ocular disposition of nanoencapsulated acyclovir and ganciclovir via intravitreal injection in rabbit's eye. Drug Delivery, 3(2), 93-97 (1996).
    • (1996) Drug Delivery , vol.3 , Issue.2 , pp. 93-97
    • El-Samaligy, M.S.1
  • 44
    • 0025907435 scopus 로고
    • Preparation and purification of polyisohexylcyanoacrylate nanocapsules
    • F. Chouinard, et al., Preparation and purification of polyisohexylcyanoacrylate nanocapsules. International Journal of Pharmaceutics, 72(3), 211-217 (1991).
    • (1991) International Journal of Pharmaceutics , vol.72 , Issue.3 , pp. 211-217
    • Chouinard, F.1
  • 45
    • 0022631242 scopus 로고
    • Development of a new process for the manufacture of polyisobutylcyanoacrylate nanocapsules
    • N. Al Khouri Fallouh, et al., Development of a new process for the manufacture of polyisobutylcyanoacrylate nanocapsules. International Journal of Pharmaceutics, 28(2-3), 125-132 (1986).
    • (1986) International Journal of Pharmaceutics , vol.28 , Issue.2-3 , pp. 125-132
    • Al Khouri Fallouh, N.1
  • 46
    • 0028791550 scopus 로고
    • Influence of the preparation conditions on poly(ethylcyanoacrylate) nanocapsule formation
    • G. Puglisi, et al., Influence of the preparation conditions on poly(ethylcyanoacrylate) nanocapsule formation. International Journal of Pharmaceutics, 125(2), 283-287 (1995).
    • (1995) International Journal of Pharmaceutics , vol.125 , Issue.2 , pp. 283-287
    • Puglisi, G.1
  • 47
    • 20444434285 scopus 로고    scopus 로고
    • In situ synthesis of temperature-sensitive hollow microspheres via interfacial polymerization
    • Q. Sun, Y. Deng, In situ synthesis of temperature-sensitive hollow microspheres via interfacial polymerization. Journal of the American Chemical Society, 127(23), 8274-8275 (2005).
    • (2005) Journal of the American Chemical Society , vol.127 , Issue.23 , pp. 8274-8275
    • Sun, Q.1    Deng, Y.2
  • 48
    • 0024578048 scopus 로고
    • Preparation of microspheres and microcapsules by interfacial polycondensation techniques
    • R. Arshady, Preparation of microspheres and microcapsules by interfacial polycondensation techniques. Journal of Microencapsulation, 6(1), 13-28 (1989).
    • (1989) Journal of Microencapsulation , vol.6 , Issue.1 , pp. 13-28
    • Arshady, R.1
  • 50
    • 0001704888 scopus 로고
    • Interfacial polycondensation. II. Fundamentals of polymer formation at liquid interfaces
    • P.W. Morgan, S.L.Kwolek, Interfacial polycondensation. II. Fundamentals of polymer formation at liquid interfaces. Journal of Polymer Science, 40(137), 299-327 (1959).
    • (1959) Journal of Polymer Science , vol.40 , Issue.137 , pp. 299-327
    • Morgan, P.W.1    Kwolek, S.L.2
  • 51
    • 32844462150 scopus 로고    scopus 로고
    • Simultaneous emulsification and interfacial polycondensation for the preparation of colloidal suspensions of nanocapsules
    • K. Bouchemal, et al., Simultaneous emulsification and interfacial polycondensation for the preparation of colloidal suspensions of nanocapsules. Materials Science and Engineering: C, 26(2-3), 472-480 (2006).
    • (2006) Materials Science and Engineering: C , vol.26 , Issue.2-3 , pp. 472-480
    • Bouchemal, K.1
  • 52
    • 0022571629 scopus 로고
    • Interfacial polymerization, a useful method for the preparation of polymethylcyanoacrylate nanoparticles
    • H-J.Krause, A. Schwarz, P. Rohdewald, Interfacial polymerization, a useful method for the preparation of polymethylcyanoacrylate nanoparticles. Drug Development and Industrial Pharmacy, 12(4), 527-552 (1986).
    • (1986) Drug Development and Industrial Pharmacy , vol.12 , Issue.4 , pp. 527-552
    • Krause, H.-J.1    Schwarz, A.2    Rohdewald, P.3
  • 53
    • 0346157325 scopus 로고    scopus 로고
    • Synthesis and characterization of polyurethane and poly(ether urethane) nanocapsules using a new technique of interfacial polycondensation combined to spontaneous emulsification
    • K.Bouchemal, et al., Synthesis and characterization of polyurethane and poly(ether urethane) nanocapsules using a new technique of interfacial polycondensation combined to spontaneous emulsification. International Journal of Pharmaceutics, 269(1), 89-100 (2004).
    • (2004) International Journal of Pharmaceutics , vol.269 , Issue.1 , pp. 89-100
    • Bouchemal, K.1
  • 54
    • 0035030718 scopus 로고    scopus 로고
    • Characterization of microcapsules prepared by interfacial polycondensation of methylene bis(phenyl isocyanate) with hexamethylene diamine
    • E. Jabbari, Characterization of microcapsules prepared by interfacial polycondensation of methylene bis(phenyl isocyanate) with hexamethylene diamine. Iranian Polymer Journal, 10(1), 33-43 (2001).
    • (2001) Iranian Polymer Journal , vol.10 , Issue.1 , pp. 33-43
    • Jabbari, E.1
  • 55
    • 33744790309 scopus 로고    scopus 로고
    • Polyamides nanocapsules: Modeling and wall thickness estimation
    • K. Bouchemal, et al., Polyamides nanocapsules: Modeling and wall thickness estimation. AIChE Journal, 52(6), 2161-2170 (2006).
    • (2006) AIChE Journal , vol.52 , Issue.6 , pp. 2161-2170
    • Bouchemal, K.1
  • 56
    • 17444428918 scopus 로고    scopus 로고
    • Interfacial polycondensation encapsulation in miniemulsion
    • L. Torini, J.F. Argillier, N. Zydowicz, Interfacial polycondensation encapsulation in miniemulsion. Macromolecules, 38(8), 3225-3236 (2005).
    • (2005) Macromolecules , vol.38 , Issue.8 , pp. 3225-3236
    • Torini, L.1    Argillier, J.F.2    Zydowicz, N.3
  • 57
    • 33750081114 scopus 로고    scopus 로고
    • Stability studies on colloidal suspensions of polyurethane nanocapsules
    • K. Bouchemal, et al., Stability studies on colloidal suspensions of polyurethane nanocapsules. Journal of Nanoscience and Nanotechnology, 6(9-10), 3187-3192 (2006).
    • (2006) Journal of Nanoscience and Nanotechnology , vol.6 , Issue.9-10 , pp. 3187-3192
    • Bouchemal, K.1
  • 58
    • 0017844057 scopus 로고
    • Improved stability of proteins immobilized in microparticles prepared by a modified emulsion polymerization technique
    • B.I. Ekman, I. Sjöholm, Improved stability of proteins immobilized in microparticles prepared by a modified emulsion polymerization technique. Journal of Pharmaceutical Sciences, 67(5), 693-696 (1978).
    • (1978) Journal of Pharmaceutical Sciences , vol.67 , Issue.5 , pp. 693-696
    • Ekman, B.I.1    Sjöholm, I.2
  • 59
    • 0028283741 scopus 로고
    • Calcitonin and insulin in isobutylcyanoacrylate nanocapsules: protection against proteases and effect on intestinal absorption in rats
    • P.J. Lowe, C.S. Temple, Calcitonin and insulin in isobutylcyanoacrylate nanocapsules: protection against proteases and effect on intestinal absorption in rats. Journal of Pharmacy and Pharmacology, 46(7), 547-552 (1994).
    • (1994) Journal of Pharmacy and Pharmacology , vol.46 , Issue.7 , pp. 547-552
    • Lowe, P.J.1    Temple, C.S.2
  • 61
    • 0024563970 scopus 로고
    • Manufacture of polyalkylcyanoacrylate nanoparticles with pilocarpine and timolol by micelle polymerization: Factors influencing particle formation
    • T. Harmia-Pulkkinen, A. Tuomi, E. Kristoffersson, Manufacture of polyalkylcyanoacrylate nanoparticles with pilocarpine and timolol by micelle polymerization: Factors influencing particle formation. Journal of Microencapsulation, 6(1), 87-93 (1989).
    • (1989) Journal of Microencapsulation , vol.6 , Issue.1 , pp. 87-93
    • Harmia-Pulkkinen, T.1    Tuomi, A.2    Kristoffersson, E.3
  • 62
    • 0017288984 scopus 로고
    • New adjuvants on a polymethylmethacrylate base
    • J.P. Kreuter, P. Speiser, New adjuvants on a polymethylmethacrylate base. Infection and Immunity, 13(1), 204-210 (1976).
    • (1976) Infection and Immunity , vol.13 , Issue.1 , pp. 204-210
    • Kreuter, J.P.1    Speiser, P.2
  • 63
    • 0022510846 scopus 로고
    • Purification et propriétés physico-chimiques des suspensions de nanoparticules de polymére
    • A. Rolland, et al., Purification et propriétés physico-chimiques des suspensions de nanoparticules de polymére. Journal de Pharmacie de Belgique, 41, 94-105 (1986).
    • (1986) Journal de Pharmacie de Belgique , vol.41 , pp. 94-105
    • Rolland, A.1
  • 65
    • 0022969998 scopus 로고
    • Ocular drug delivery of progesterone using nanoparticles
    • V.H.K. Li, et al., Ocular drug delivery of progesterone using nanoparticles. Journal of Microencapsulation, 3(3), 213-218 (1986).
    • (1986) Journal of Microencapsulation , vol.3 , Issue.3 , pp. 213-218
    • Li, V.H.K.1
  • 66
    • 0020021362 scopus 로고
    • Triamcinolone diacetate nanoparticles: a sustained release drug delivery system suitable for parental administration
    • M.S. El-Samaligy, P. Rohdewald, Triamcinolone diacetate nanoparticles: a sustained release drug delivery system suitable for parental administration. Pharmaceutica Acta Helvetiae, 57, 201-204 (1982).
    • (1982) Pharmaceutica Acta Helvetiae , vol.57 , pp. 201-204
    • El-Samaligy, M.S.1    Rohdewald, P.2
  • 67
    • 0001901784 scopus 로고
    • Nanoparticle: Preparation and applications
    • In Microcapsules and Nanoparticles in Medicine and Pharmacy, M. Donbrow (ed.). Boca Raton, FL: CRC Press
    • J. Kreuter, Nanoparticle: Preparation and applications. In Microcapsules and Nanoparticles in Medicine and Pharmacy, M. Donbrow (ed.). Boca Raton, FL: CRC Press (1992).
    • (1992)
    • Kreuter, J.1
  • 68
    • 0020615103 scopus 로고
    • Pharmacokinetics and distribution of a biodegradable drug-carrier
    • L. Grislain, et al., Pharmacokinetics and distribution of a biodegradable drug-carrier. International Journal of Pharmaceutics, 15(3), 335-345 (1983).
    • (1983) International Journal of Pharmaceutics , vol.15 , Issue.3 , pp. 335-345
    • Grislain, L.1
  • 69
    • 0030691084 scopus 로고    scopus 로고
    • Poly(alkyl cyanoacrylate) nanocapsules as a delivery system in the rat for octreotide, a long-acting somatostatin analogue
    • C. Damgé, et al., Poly(alkyl cyanoacrylate) nanocapsules as a delivery system in the rat for octreotide, a long-acting somatostatin analogue. Journal of Pharmacy and Pharmacology, 49(10), 949-954 (1997)
    • (1997) Journal of Pharmacy and Pharmacology , vol.49 , Issue.10 , pp. 949-954
    • Damgé, C.1
  • 70
    • 0025854457 scopus 로고
    • The preparation and acute antihypertensive effects of a nanocapsular form of darodipine, a dihydropyridine calcium entry blocker
    • B. Hubert, et al., The preparation and acute antihypertensive effects of a nanocapsular form of darodipine, a dihydropyridine calcium entry blocker. Pharmaceutical Research, 8(6), 734-738 (1991).
    • (1991) Pharmaceutical Research , vol.8 , Issue.6 , pp. 734-738
    • Hubert, B.1
  • 71
    • 0028917794 scopus 로고
    • Nanocapsules with a reduced liver uptake: Targeting of phthalocyanines toEMT-6 mouse mammary tumour in vivo
    • V. Lenaerts, et al., Nanocapsules with a reduced liver uptake: Targeting of phthalocyanines toEMT-6 mouse mammary tumour in vivo. European Journal of Pharmaceutics and Biopharmaceutics, 41, 38-43 (1995).
    • (1995) European Journal of Pharmaceutics and Biopharmaceutics , vol.41 , pp. 38-43
    • Lenaerts, V.1
  • 73
    • 84887257712 scopus 로고    scopus 로고
    • Emulsion polymerization. 2012
    • Emulsion polymerization. 2012: http://en.wikipedia.org.
  • 74
    • 9444247318 scopus 로고    scopus 로고
    • Surfactants: Types and Uses
    • FIRP Booklet # 300A
    • J-L. Salager, Surfactants: Types and Uses. FIRP Booklet # 300A (1999).
    • (1999)
    • Salager, J.-L.1
  • 75
    • 20144384276 scopus 로고    scopus 로고
    • New green surfactants for emulsion polymerization
    • A.M. Fernandez, et al., New green surfactants for emulsion polymerization. Progress in Organic Coatings, 53(4), 246-255 (2005).
    • (2005) Progress in Organic Coatings , vol.53 , Issue.4 , pp. 246-255
    • Fernandez, A.M.1
  • 76
    • 33947732191 scopus 로고    scopus 로고
    • The effect of monomers on the formulation of polymeric nanocapsules based on polyureas and polyamides
    • I. Montasser, S. Briançon, H. Fessi, The effect of monomers on the formulation of polymeric nanocapsules based on polyureas and polyamides. International Journal of Pharmaceutics, 335(1-2), 176-179 (2007).
    • (2007) International Journal of Pharmaceutics , vol.335 , Issue.1-2 , pp. 176-179
    • Montasser, I.1    Briancon, S.2    Fessi, H.3
  • 77
    • 0344439650 scopus 로고
    • Preparation of model poly(vinyl toluene) lattices and characterization of their surface charge by titration and electrophoresis
    • P. Bagchi, B.V. Gray, S.M. Birnbaum, Preparation of model poly(vinyl toluene) lattices and characterization of their surface charge by titration and electrophoresis. Journal of Colloid and Interface Science, 69(3), 502-552 (1979).
    • (1979) Journal of Colloid and Interface Science , vol.69 , Issue.3 , pp. 502-552
    • Bagchi, P.1    Gray, B.V.2    Birnbaum, S.M.3
  • 78
    • 0003160564 scopus 로고    scopus 로고
    • Control of particle morphology
    • In Emulsion Polymerization and Emulsion Polymers, P.A. Lovell, M.S. El-Aasser (eds). New York: John Wiley and Sons
    • V. Dimonie, et al., Control of particle morphology. In Emulsion Polymerization and Emulsion Polymers, P.A. Lovell, M.S. El-Aasser (eds). New York: John Wiley and Sons (1997).
    • (1997)
    • Dimonie, V.1
  • 79
    • 0032770141 scopus 로고    scopus 로고
    • Non-equilibrium particle morphology development in seeded emulsion polymerization
    • J. Stubbs, et al., Non-equilibrium particle morphology development in seeded emulsion polymerization. 1: Penetration of monomer and radicals as a function of monomer feed rate during second stage polymerization. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 153(1-3), 255-270 (1999).
    • (1999) , vol.153 , Issue.1-3 , pp. 255-270
    • Stubbs, J.1
  • 80
    • 0025664377 scopus 로고
    • Morphology development of polymeric microparticles in aqueous dispersions. I. Thermodynamic considerations
    • D.C. Sundberg, et al., Morphology development of polymeric microparticles in aqueous dispersions. I. Thermodynamic considerations. Journal of Applied Polymer Science, 41(7-8), 1425-1442 (1990).
    • (1990) Journal of Applied Polymer Science , vol.41 , Issue.7-8 , pp. 1425-1442
    • Sundberg, D.C.1
  • 82
    • 0037351265 scopus 로고    scopus 로고
    • Fundamental studies on morphology control for latex systems with application to waterborne coatings: The effect of polymer radical mobility in latex particles during polymerization
    • J Stubbs, D. Sundberg, Fundamental studies on morphology control for latex systems with application to waterborne coatings: The effect of polymer radical mobility in latex particles during polymerization. Journal of Coatings Technology, 75(938), 59-67 (2003).
    • (2003) Journal of Coatings Technology , vol.75 , Issue.938 , pp. 59-67
    • Stubbs, J.1    Sundberg, D.2
  • 83
    • 0033659793 scopus 로고    scopus 로고
    • Influence of glass transition temperature on latex particle morphology
    • L.E. Ivarsson, L.E., O.J. Karlsson, D.C. Sundberg, Influence of glass transition temperature on latex particle morphology. Macromolecular Symposia, 151(1), 407-412 (2000).
    • (2000) Macromolecular Symposia , vol.151 , Issue.1 , pp. 407-412
    • Ivarsson, L.E.1    Karlsson, O.J.2    Sundberg, D.C.3
  • 84
    • 84887228495 scopus 로고
    • Comparison of Body Distribution of Poly(Vinyl Alcohol) with Other Water-Soluble Polymers after Intravenous Administration
    • Chichester: Wiley
    • T. Yamaoka, Tabata, Y. Ikada, Comparison of Body Distribution of Poly(Vinyl Alcohol) with Other Water-Soluble Polymers after Intravenous Administration. Vol. 47. Chichester: Wiley (1995).
    • (1995)
    • Yamaoka, T.1    Tabata, Y.2    Ikada3
  • 85
    • 0028337034 scopus 로고
    • Distribution and tissue uptake of poly(ethylene glycol) with different molecular weights after intravenous administration to mice
    • T. Yamaoka, Y. Tabata, Y. Ikada, Distribution and tissue uptake of poly(ethylene glycol) with different molecular weights after intravenous administration to mice. Journal of Pharmaceutical Sciences, 83(4), 601-606 (1994).
    • (1994) Journal of Pharmaceutical Sciences , vol.83 , Issue.4 , pp. 601-606
    • Yamaoka, T.1    Tabata, Y.2    Ikada, Y.3
  • 86
    • 0028913713 scopus 로고
    • Fate of water-soluble polymers administered via different routes
    • T. Yamaoka, Y. Tabata, Y. Ikada, Fate of water-soluble polymers administered via different routes. Journal of Pharmaceutical Sciences, 84(3), 349-354 (1995).
    • (1995) Journal of Pharmaceutical Sciences , vol.84 , Issue.3 , pp. 349-354
    • Yamaoka, T.1    Tabata, Y.2    Ikada, Y.3
  • 87
    • 0346634895 scopus 로고    scopus 로고
    • In vitro cytotoxicity testing of polycations: Influence of polymer structure on cell viability and hemolysis
    • D. Fischer, et al., In vitro cytotoxicity testing of polycations: Influence of polymer structure on cell viability and hemolysis. Biomaterials, 24(7), 1121-1131 (2003).
    • (2003) Biomaterials , vol.24 , Issue.7 , pp. 1121-1131
    • Fischer, D.1
  • 88
    • 77955879616 scopus 로고    scopus 로고
    • Polycation cytotoxicity: A delicate matter for nucleic acid therapy-focus on polyethylenimine
    • Soft Matter
    • L. Parhamifar, et al., Polycation cytotoxicity: A delicate matter for nucleic acid therapy-focus on polyethylenimine. Soft Matter (2010).
    • (2010)
    • Parhamifar, L.1
  • 89
    • 0028997949 scopus 로고
    • In vitro cytotoxicity of macromolecules in different cell culture systems
    • S. Choksakulnimitr, et al., In vitro cytotoxicity of macromolecules in different cell culture systems. Journal of Controlled Release, 34(3), 233-241 (1995).
    • (1995) Journal of Controlled Release , vol.34 , Issue.3 , pp. 233-241
    • Choksakulnimitr, S.1
  • 90
    • 33746379251 scopus 로고    scopus 로고
    • Blood compatibility of novel water soluble hyperbranched polyglycerol-based multivalent cationic polymers and their interaction with DNA
    • R.K. Kainthan, et al., Blood compatibility of novel water soluble hyperbranched polyglycerol-based multivalent cationic polymers and their interaction with DNA. Biomaterials, 27(31), 5377-90 (2006).
    • (2006) Biomaterials , vol.27 , Issue.31 , pp. 5377-5390
    • Kainthan, R.K.1
  • 91
    • 84887234018 scopus 로고    scopus 로고
    • Recent advances in the preparation of drug-loaded poly(alkyl cyanoacrylate) colloidal particles for cancer treatment: Nanoprecipitation vs. polymerization
    • G. Yordanov, C. Dushkin, Recent advances in the preparation of drug-loaded poly(alkyl cyanoacrylate) colloidal particles for cancer treatment: Nanoprecipitation vs. polymerization. http://costd43.lcpe.uni-sofia.bg/files/Articles/Yordanov_ NW2011_rev2.pdf, 2012.
    • (2012)
    • Yordanov, G.1    Dushkin, C.2
  • 92
    • 79953277370 scopus 로고    scopus 로고
    • Computational analysis of mixing and scale-up in emulsion polymerization reactors
    • J. Pohn, et al., Computational analysis of mixing and scale-up in emulsion polymerization reactors. Macromolecular Symposia, 302(1), 133-141 (2011).
    • (2011) Macromolecular Symposia , vol.302 , Issue.1 , pp. 133-141
    • Pohn, J.1
  • 93
    • 0024088996 scopus 로고
    • Perspectives on industrial reactor control
    • J.R. Richards, Schnelle, P.D. Jr., Perspectives on industrial reactor control. Chem. Eng. Prog., 84(10), 32-36 (1988).
    • (1988) Chem. Eng. Prog. , vol.84 , Issue.10 , pp. 32-36
    • Richards, J.R.1    Schnelle, P.D.2
  • 94
    • 33747883073 scopus 로고    scopus 로고
    • Congalidis, measurement and control of polymerization reactors
    • J.R. Richards, Congalidis, measurement and control of polymerization reactors. Chemical Engineering and Processing, 30(10-12), 1447-1463 (2006).
    • (2006) Chemical Engineering and Processing , vol.30 , Issue.10-12 , pp. 1447-1463
    • Richards, J.R.1
  • 95
    • 0004056396 scopus 로고
    • Control of Polymerization Reactors
    • New York: Marcel Dekker Inc.
    • F.J. Schork, P.B. Deshpande, K.W. Leffew, Control of Polymerization Reactors. New York: Marcel Dekker Inc. (1993).
    • (1993)
    • Schork, F.J.1    Deshpande, P.B.2    Leffew, K.W.3
  • 96
    • 0030195945 scopus 로고    scopus 로고
    • ESR study of MMA batch emulsion polymerization in real time: Effects of particle size
    • H.Y. Parker, D.G. Westmoreland, H.R. Chang, ESR study of MMA batch emulsion polymerization in real time: Effects of particle size. Macromolecules, 29(15), 5119-5127 (1996).
    • (1996) Macromolecules , vol.29 , Issue.15 , pp. 5119-5127
    • Parker, H.Y.1    Westmoreland, D.G.2    Chang, H.R.3
  • 97
    • 0031189174 scopus 로고    scopus 로고
    • Semibatch seeded emulsion polymerization of acrylic monomers: Bimodal particle size distribution
    • C.S. Chern, et al., Semibatch seeded emulsion polymerization of acrylic monomers: Bimodal particle size distribution. Journal of Macromolecular Science, Part A, 34(7), 1221-1236 (1997).
    • (1997) Journal of Macromolecular Science, Part A , vol.34 , Issue.7 , pp. 1221-1236
    • Chern, C.S.1
  • 98
    • 0346615686 scopus 로고    scopus 로고
    • Characterization of polybutyl acrylate latex particles stabilized by a reactive surfactant, in particle size distribution III
    • C.S. Chern, Y.-C. Chen, Characterization of polybutyl acrylate latex particles stabilized by a reactive surfactant, in particle size distribution III. American Chemical Society, 161-179 (1998).
    • (1998) American Chemical Society , pp. 161-179
    • Chern, C.S.1    Chen, Y.-C.2
  • 99
    • 0035814203 scopus 로고    scopus 로고
    • Study of different types of monomer emulsion feedings to semibatch emulsion polymerization reactors
    • S. Sajjadi, Study of different types of monomer emulsion feedings to semibatch emulsion polymerization reactors. Journal of Applied Polymer Science, 82(10), 2472-2477 (2001).
    • (2001) Journal of Applied Polymer Science , vol.82 , Issue.10 , pp. 2472-2477
    • Sajjadi, S.1
  • 100
    • 0036695157 scopus 로고    scopus 로고
    • Operation of semi-batch emulsion polymerisation reactors: Modelling, validation and effect of operating conditions
    • J. Zeaiter, et al., Operation of semi-batch emulsion polymerisation reactors: Modelling, validation and effect of operating conditions. Chemical Engineering Science, 57(15), 2955-2969 (2002).
    • (2002) Chemical Engineering Science , vol.57 , Issue.15 , pp. 2955-2969
    • Zeaiter, J.1
  • 101
    • 84887219607 scopus 로고
    • Influence of parameters and drying conditions of lattices on the particle size of the PVC powder obtained
    • E.L. Eskin, et al., Influence of parameters and drying conditions of lattices on the particle size of the PVC powder obtained. Plasticheskie Massy, 1, 3-4 (1995).
    • (1995) Plasticheskie Massy , vol.1 , pp. 3-4
    • Eskin, E.L.1
  • 102
    • 0018467565 scopus 로고
    • Scaleup factors of tubular emulsion polymerization reactors
    • T. Vatanatham, H. Forsyth, Scaleup factors of tubular emulsion polymerization reactors. Polymer Engineering & Science, 19(7), 482-487 (1979).
    • (1979) Polymer Engineering & Science , vol.19 , Issue.7 , pp. 482-487
    • Vatanatham, T.1    Forsyth, H.2
  • 103
    • 0033887644 scopus 로고    scopus 로고
    • Ultrasound-assisted emulsion polymerization of methyl methacrylate and styrene
    • H.M.K. Cheung, K. Gaddam, Ultrasound-assisted emulsion polymerization of methyl methacrylate and styrene. Journal of Applied Polymer Science, 76(1), 101-104 (2000).
    • (2000) Journal of Applied Polymer Science , vol.76 , Issue.1 , pp. 101-104
    • Cheung, H.M.K.1    Gaddam, K.2
  • 104
    • 34848913431 scopus 로고    scopus 로고
    • Ultrasound initiated miniemulsion polymerization of methacrylate monomers
    • B.M. Teo, et al., Ultrasound initiated miniemulsion polymerization of methacrylate monomers. Ultrasonics Sonochemistry, 15(1), 89-94 (2008).
    • (2008) Ultrasonics Sonochemistry , vol.15 , Issue.1 , pp. 89-94
    • Teo, B.M.1
  • 105
    • 80051471031 scopus 로고    scopus 로고
    • Analysis of semibatch emulsion polymerization: Role of ultrasound and initiator
    • B.A. Bhanvase, et al., Analysis of semibatch emulsion polymerization: Role of ultrasound and initiator. Ultrasonics Sonochemistry, 19, 97-103 (2012).
    • (2012) Ultrasonics Sonochemistry , vol.19 , pp. 97-103
    • Bhanvase, B.A.1


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