-
1
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
M. Soda, Y.L. Choi, and M. Enomoto Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer Nature 448 2007 561 566
-
(2007)
Nature
, vol.448
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
-
2
-
-
84865431278
-
Results of a global phase II study with crizotinib in advanced ALK-positive non-small cell lung cancer (NSCLC)
-
(abstract 7533)
-
D.W. Kim, M.J. Ahn, and Y. Shi Results of a global phase II study with crizotinib in advanced ALK-positive non-small cell lung cancer (NSCLC) ASCO Meeting Abstracts 30 15 suppl 2012 (abstract 7533)
-
(2012)
ASCO Meeting Abstracts
, vol.30
, Issue.15 SUPPL.
-
-
Kim, D.W.1
Ahn, M.J.2
Shi, Y.3
-
3
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
E.L. Kwak, Y.J. Bang, and D.R. Camidge Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer N Engl J Med 363 2010 1693 1703
-
(2010)
N Engl J Med
, vol.363
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
-
4
-
-
84879071011
-
Crizotinib versus chemotherapy in advanced ALK-positive lung cancer
-
A.T. Shaw, D.W. Kim, and K. Nakagawa Crizotinib versus chemotherapy in advanced ALK-positive lung cancer N Engl J Med 368 2013 2385 2394
-
(2013)
N Engl J Med
, vol.368
, pp. 2385-2394
-
-
Shaw, A.T.1
Kim, D.W.2
Nakagawa, K.3
-
5
-
-
0030891198
-
LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes
-
C. Shih, V.J. Chen, and L.S. Gossett LY231514, a pyrrolo[2,3-d] pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes Cancer Res 57 1997 1116 1123
-
(1997)
Cancer Res
, vol.57
, pp. 1116-1123
-
-
Shih, C.1
Chen, V.J.2
Gossett, L.S.3
-
6
-
-
0032950347
-
Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis
-
L.G. Mendelsohn, C. Shih, and V.J. Chen Enzyme inhibition, polyglutamation, and the effect of LY231514 (MTA) on purine biosynthesis Semin Oncol 26 2 suppl 6 1999 42 47
-
(1999)
Semin Oncol
, vol.26
, Issue.2 SUPPL. 6
, pp. 42-47
-
-
Mendelsohn, L.G.1
Shih, C.2
Chen, V.J.3
-
7
-
-
84860352732
-
Treating ALK-positive lung cancer-early successes and future challenges
-
D.R. Camidge, and R.C. Doebele Treating ALK-positive lung cancer-early successes and future challenges Nat Rev Clin Oncol 9 2012 268 277
-
(2012)
Nat Rev Clin Oncol
, vol.9
, pp. 268-277
-
-
Camidge, D.R.1
Doebele, R.C.2
-
8
-
-
2442661845
-
Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
-
N. Hanna, F.A. Shepherd, and F.V. Fossella Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy J Clin Oncol 22 2004 1589 1597
-
(2004)
J Clin Oncol
, vol.22
, pp. 1589-1597
-
-
Hanna, N.1
Shepherd, F.A.2
Fossella, F.V.3
-
9
-
-
64049115311
-
The differential efficacy of pemetrexed according to NSCLC histology: A review of two Phase III studies
-
G. Scagliotti, N. Hanna, and F. Fossella The differential efficacy of pemetrexed according to NSCLC histology: a review of two Phase III studies Oncologist 14 2009 253 263
-
(2009)
Oncologist
, vol.14
, pp. 253-263
-
-
Scagliotti, G.1
Hanna, N.2
Fossella, F.3
-
10
-
-
79953029071
-
Anaplastic lymphoma kinase gene rearrangements in non-small cell lung cancer are associated with prolonged progression-free survival on pemetrexed
-
D.R. Camidge, S.A. Kono, and X. Lu Anaplastic lymphoma kinase gene rearrangements in non-small cell lung cancer are associated with prolonged progression-free survival on pemetrexed J Thorac Oncol 6 2011 774 780
-
(2011)
J Thorac Oncol
, vol.6
, pp. 774-780
-
-
Camidge, D.R.1
Kono, S.A.2
Lu, X.3
-
11
-
-
80052261903
-
Anaplastic lymphoma kinase translocation: A predictive biomarker of pemetrexed in patients with non-small cell lung cancer
-
J.O. Lee, T.M. Kim, and S.H. Lee Anaplastic lymphoma kinase translocation: a predictive biomarker of pemetrexed in patients with non-small cell lung cancer J Thorac Oncol 6 2011 1474 1480
-
(2011)
J Thorac Oncol
, vol.6
, pp. 1474-1480
-
-
Lee, J.O.1
Kim, T.M.2
Lee, S.H.3
-
12
-
-
70349336416
-
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
-
A.T. Shaw, B.Y. Yeap, and M. Mino-Kenudson Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK J Clin Oncol 27 2009 4247 4253
-
(2009)
J Clin Oncol
, vol.27
, pp. 4247-4253
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
-
13
-
-
70349310325
-
Phase II-I-II study of two different doses and schedules of pralatrexate, a high-affinity substrate for the reduced folate carrier, in patients with relapsed or refractory lymphoma reveals marked activity in T-cell malignancies
-
O.A. O'Connor, S. Horwitz, and P. Hamlin Phase II-I-II study of two different doses and schedules of pralatrexate, a high-affinity substrate for the reduced folate carrier, in patients with relapsed or refractory lymphoma reveals marked activity in T-cell malignancies J Clin Oncol 27 2009 4357 4364
-
(2009)
J Clin Oncol
, vol.27
, pp. 4357-4364
-
-
O'Connor, O.A.1
Horwitz, S.2
Hamlin, P.3
-
14
-
-
63849263983
-
The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: New insights in ALK-mediated pathogenesis and the treatment of ALCL
-
F.E. Boccalatte, C. Voena, and C. Riganti The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL Blood 113 2009 2776 2790
-
(2009)
Blood
, vol.113
, pp. 2776-2790
-
-
Boccalatte, F.E.1
Voena, C.2
Riganti, C.3
-
15
-
-
84876415170
-
Thymidylate synthase (TS) gene expression in patients with ALK positive (+) non-small cell lung cancer (NSCLC): Implications for therapy
-
(abstract 7582)
-
D.R. Gandara, E. Huang, and S. Desai Thymidylate synthase (TS) gene expression in patients with ALK positive (+) non-small cell lung cancer (NSCLC): implications for therapy ASCO Meeting Abstracts 30 15 suppl 2012 (abstract 7582)
-
(2012)
ASCO Meeting Abstracts
, vol.30
, Issue.15 SUPPL. 3
-
-
Gandara, D.R.1
Huang, E.2
Desai, S.3
-
16
-
-
84887233977
-
ALK-driven lung cancer: Potential therapeutic strategies for treatment and prevention of drug resistance
-
(abstract 5594)
-
A.B. Pilling, A.T. Le, and A. Tan ALK-driven lung cancer: potential therapeutic strategies for treatment and prevention of drug resistance AACR Annual Meeting Abstracts 2012 (abstract 5594)
-
(2012)
AACR Annual Meeting Abstracts
-
-
Pilling, A.B.1
Le, A.T.2
Tan, A.3
-
17
-
-
84866934606
-
Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: Updated results from a phase 1 study
-
D.R. Camidge, Y. Bang, and E.L. Kwak Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study Lancet Oncol 13 2012 1011 1019
-
(2012)
Lancet Oncol
, vol.13
, pp. 1011-1019
-
-
Camidge, D.R.1
Bang, Y.2
Kwak, E.L.3
-
18
-
-
78349237453
-
Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment
-
D.R. Camidge, S.A. Kono, and A. Flacco Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment Clin Cancer Res 16 2010 5581 5590
-
(2010)
Clin Cancer Res
, vol.16
, pp. 5581-5590
-
-
Camidge, D.R.1
Kono, S.A.2
Flacco, A.3
-
19
-
-
78649508952
-
ALK gene rearrangements in unselected caucasians with non-small cell lung carcinoma (NSCLC)
-
(abstract 10533)
-
M. Varella-Garcia, Y. Cho, and X. Lu ALK gene rearrangements in unselected caucasians with non-small cell lung carcinoma (NSCLC) ASCO Meeting Abstracts 28 15 suppl 2010 (abstract 10533)
-
(2010)
ASCO Meeting Abstracts
, vol.28
, Issue.15 SUPPL.
-
-
Varella-Garcia, M.1
Cho, Y.2
Lu, X.3
-
20
-
-
67650305798
-
New TNM classification for non-small-cell lung cancer
-
L.T. Tanoue, and F.C. Detterbeck New TNM classification for non-small-cell lung cancer Expert Rev Anticancer Ther 9 2009 413 423
-
(2009)
Expert Rev Anticancer Ther
, vol.9
, pp. 413-423
-
-
Tanoue, L.T.1
Detterbeck, F.C.2
-
21
-
-
79957487193
-
CSF concentration of the anaplastic lymphoma kinase inhibitor crizotinib
-
D.B. Costa, S. Kobayashi, and S.S. Pandya CSF concentration of the anaplastic lymphoma kinase inhibitor crizotinib J Clin Oncol 29 2011 e443 e445
-
(2011)
J Clin Oncol
, vol.29
-
-
Costa, D.B.1
Kobayashi, S.2
Pandya, S.S.3
-
22
-
-
84870317390
-
Local ablative therapy of oligoprogressive disease prolongs disease control by tyrosine kinase inhibitors in oncogene-addicted non-small-cell lung cancer
-
A.J. Weickhardt, B. Scheier, and J.M. Burke Local ablative therapy of oligoprogressive disease prolongs disease control by tyrosine kinase inhibitors in oncogene-addicted non-small-cell lung cancer J Thorac Oncol 7 2012 1807 1814
-
(2012)
J Thorac Oncol
, vol.7
, pp. 1807-1814
-
-
Weickhardt, A.J.1
Scheier, B.2
Burke, J.M.3
-
23
-
-
57849117384
-
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
-
E.A. Eisenhauer, P. Therasse, and J. Bogaerts New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1) Eur J Cancer 45 2009 228 247
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogaerts, J.3
-
25
-
-
84870956882
-
A large retrospective analysis of the activity of pemetrexed (PEM) in patients (pts) with ALK-positive (ALK+) non-small cell lung cancer (NSCLC) prior to crizotinib (CRIZ)
-
(abstract 7599)
-
G. Scagliotti, D.W. Kim, and A.T. Shaw A large retrospective analysis of the activity of pemetrexed (PEM) in patients (pts) with ALK-positive (ALK+) non-small cell lung cancer (NSCLC) prior to crizotinib (CRIZ) ASCO Meeting Abstracts 30 15 suppl 2012 (abstract 7599)
-
(2012)
ASCO Meeting Abstracts
, vol.30
, Issue.15 SUPPL.
-
-
Scagliotti, G.1
Kim, D.W.2
Shaw, A.T.3
-
26
-
-
33749587054
-
Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase
-
P. Ceppi, M. Volante, and S. Saviozzi Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase Cancer 107 2006 1589 1596
-
(2006)
Cancer
, vol.107
, pp. 1589-1596
-
-
Ceppi, P.1
Volante, M.2
Saviozzi, S.3
-
27
-
-
84876507123
-
Pemetrexed-based chemotherapy in patients with advanced, ALK-positive non-small cell lung cancer
-
A.T. Shaw, A.M. Varghese, and B.J. Solomon Pemetrexed-based chemotherapy in patients with advanced, ALK-positive non-small cell lung cancer Ann Oncol 24 2013 59 66
-
(2013)
Ann Oncol
, vol.24
, pp. 59-66
-
-
Shaw, A.T.1
Varghese, A.M.2
Solomon, B.J.3
-
28
-
-
78049426102
-
ABCC11/MRP8 confers pemetrexed resistance in lung cancer
-
T. Uemura, T. Oguri, and H. Ozasa ABCC11/MRP8 confers pemetrexed resistance in lung cancer Cancer Sci 101 2010 2404 2410
-
(2010)
Cancer Sci
, vol.101
, pp. 2404-2410
-
-
Uemura, T.1
Oguri, T.2
Ozasa, H.3
-
29
-
-
84856999699
-
Mechanisms of acquired crizotinib resistance in ALK-rearranged lung Cancers
-
R. Katayama, A.T. Shaw, and T.M. Khan Mechanisms of acquired crizotinib resistance in ALK-rearranged lung Cancers Sci Transl Med 4 2012 120ra17
-
(2012)
Sci Transl Med
, vol.4
-
-
Katayama, R.1
Shaw, A.T.2
Khan, T.M.3
-
30
-
-
84856990335
-
Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer
-
R.C. Doebele, A.B. Pilling, and D.L. Aisner Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer Clin Cancer Res 18 2012 1472 1482
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1472-1482
-
-
Doebele, R.C.1
Pilling, A.B.2
Aisner, D.L.3
-
31
-
-
77950457810
-
Activity of pemetrexed on brain metastases from Non-small cell lung cancer
-
A. Bearz, I. Garassino, and M. Tiseo Activity of pemetrexed on brain metastases from Non-small cell lung cancer Lung Cancer 68 2010 264 268
-
(2010)
Lung Cancer
, vol.68
, pp. 264-268
-
-
Bearz, A.1
Garassino, I.2
Tiseo, M.3
|