The delayed addition of human mesenchymal stem cells to pre-formed endothelial cell networks results in functional vascularization of a collagen-glycosaminoglycan scaffold in vivo

Acta Biomaterialia

Volumn 9, Issue 12, 2013, Pages 9303-9316

  McFadden, T M ^a,b   Duffy, G P ^a,b   Allen, A B ^c   Stevens, H Y ^c   Schwarzmaier, S M ^a   Plesnila, N ^a   Murphy, J M ^d   Barry, F P ^d   Guldberg, R E ^c   O'Brien, F J ^a,b  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^d NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Co culture; Collagen GAG scaffold; Endothelial cells; In vivo vascularization; Mesenchymal stem cells

Indexed keywords

BLOOD VESSELS; COLLAGEN; ENDOTHELIAL CELLS; FLOWCHARTING; SCAFFOLDS (BIOLOGY); STEM CELLS; TISSUE;

CELL NETWORK; CO-CULTURES; COLLAGEN-GAG SCAFFOLDS; ENDOTHELIAL-CELLS; HUMAN MESENCHYMAL STEM CELLS; IN VIVO VASCULARIZATION; IN-VITRO; IN-VIVO; MESENCHYMAL STEM CELL; VASCULARIZATION;

CELL CULTURE;

COLLAGEN; GLYCOSAMINOGLYCAN; PLATELET DERIVED GROWTH FACTOR; TISSUE SCAFFOLD; VASCULOTROPIN;

ANASTOMOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INTERACTION; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; FUNCTIONAL ASSESSMENT; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; MESENCHYMAL STEM CELL; MICROVASCULATURE; NONHUMAN; PERICYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TISSUE IMPLANT; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULARIZATION;

RATTUS;

CO-CULTURE; COLLAGEN-GAG SCAFFOLD; ENDOTHELIAL CELLS; IN VIVO VASCULARIZATION; MESENCHYMAL STEM CELLS;

ANGIOGRAPHY; ANIMALS; BLOOD VESSELS; CATTLE; COCULTURE TECHNIQUES; COLLAGEN; GLYCOSAMINOGLYCANS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MESENCHYMAL STROMAL CELLS; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; NEOVASCULARIZATION, PHYSIOLOGIC; PLATELET-DERIVED GROWTH FACTOR; RATS; STAINING AND LABELING; TISSUE SCAFFOLDS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; X-RAY MICROTOMOGRAPHY;

EID: 84887205900     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.08.014     Document Type: Article

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