Nuclear import and export inhibitors alter capsid protein distribution in mammalian cells and reduce Venezuelan Equine Encephalitis Virus replication

Antiviral Research

Volumn 100, Issue 3, 2013, Pages 662-672

  Lundberg, Lindsay ^a   Pinkham, Chelsea ^a   Baer, Alan ^a   Amaya, Moushimi ^a   Narayanan, Aarthi ^a   Wagstaff, Kylie M ^b   Jans, David A ^b   Kehn Hall, Kylene ^a  

^a GEORGE MASON UNIVERSITY   (United States)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Capsid; Ivermectin; Mifepristone; Nuclear export; Nuclear import; Venezuelan Equine Encephalitis Virus

Indexed keywords

CAPSID PROTEIN; EXPORTIN 1; IMPORTIN BETA1; IVERMECTIN; KARYOPHERIN ALPHA; LEPTOMYCIN B; MIFEPRISTONE; NUCLEAR PROTEIN; UNCLASSIFIED DRUG; CELL RECEPTOR; EXPORTIN 1 PROTEIN; KARYOPHERIN; KARYOPHERIN BETA; KPNB1 PROTEIN, HUMAN; MACROMOLECULE; SMALL INTERFERING RNA; UNSATURATED FATTY ACID;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; ASTROCYTE CULTURE; CELL PROTECTION; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; NUCLEAR EXPORT SIGNAL; NUCLEAR IMPORT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; VENEZUELAN EQUINE ENCEPHALOMYELITIS ALPHAVIRUS; VERO CELL; VIRUS CAPSID; VIRUS INHIBITION; VIRUS REPLICATION; ACTIVE TRANSPORT; ANIMAL; ANTAGONISTS AND INHIBITORS; ASTROCYTOMA; CELL COMPARTMENTALIZATION; CELL NUCLEUS; CHLOROCEBUS AETHIOPS; DRUG EFFECTS; GENETICS; MACROMOLECULE; METABOLISM; PATHOLOGY; PHYSIOLOGY; RNA INTERFERENCE; TUMOR CELL LINE; VERO CELL LINE; VIRUS CULTURE; DRUG ANTAGONISM; DRUG EFFECT; NUCLEAR EXPORT;

MAMMALIA; MIRIDAE; VENEZUELAN EQUINE ENCEPHALITIS VIRUS;

ACTIVE TRANSPORT, CELL NUCLEUS; ALPHA KARYOPHERINS; ANIMALS; ASTROCYTOMA; BETA KARYOPHERINS; CAPSID; CELL COMPARTMENTATION; CELL LINE, TUMOR; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; CYTOPATHOGENIC EFFECT, VIRAL; ENCEPHALITIS VIRUS, VENEZUELAN EQUINE; FATTY ACIDS, UNSATURATED; HUMANS; IVERMECTIN; KARYOPHERINS; MACROMOLECULAR SUBSTANCES; MIFEPRISTONE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA INTERFERENCE; RNA, SMALL INTERFERING; VERO CELLS; VIRUS CULTIVATION; VIRUS REPLICATION;

CAPSID; IVERMECTIN; MIFEPRISTONE; NUCLEAR EXPORT; NUCLEAR IMPORT; VENEZUELAN EQUINE ENCEPHALITIS VIRUS;

EID: 84887196211     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2013.10.004     Document Type: Article

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