메뉴 건너뛰기




Volumn 74, Issue 11, 2000, Pages 5006-5015

Pegylated alpha interferon is an effective treatment for virulent venezuelan equine encephalitis virus and has profound effects on the host immune response to infection

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; MACROGOL; RECOMBINANT ALPHA INTERFERON AD; RECOMBINANT INTERLEUKIN 12; TUMOR NECROSIS FACTOR;

EID: 0034023856     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.74.11.5006-5015.2000     Document Type: Article
Times cited : (66)

References (42)
  • 1
    • 0028984619 scopus 로고
    • IL-12 activates IFN-g production through the preferential activation of CD30+ T cells
    • Alzona. M., H. M. Jack, R. I. Fisher, and T. M. Ellis. 1995. IL-12 activates IFN-g production through the preferential activation of CD30+ T cells. J. Immunol. 154:9-16.
    • (1995) J. Immunol. , vol.154 , pp. 9-16
    • Alzona, M.1    Jack, H.M.2    Fisher, R.I.3    Ellis, T.M.4
  • 2
    • 0028029170 scopus 로고
    • Cytokines in the generation of immune responses to, and resolution of, virus infection
    • Biron, C. A. 1994. Cytokines in the generation of immune responses to, and resolution of, virus infection. Curr. Opin. Immunol. 6:530-538.
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 530-538
    • Biron, C.A.1
  • 3
    • 0033082830 scopus 로고    scopus 로고
    • Interferon-alpha protects mice against lethal infection with St. Louis encephalitis virus delivered by the aerosol and subcutaneous routes
    • Brooks. T. J. G., and R. J. Phillpotts. 1999. Interferon-alpha protects mice against lethal infection with St. Louis encephalitis virus delivered by the aerosol and subcutaneous routes. Antiviral Res. 41:57-64.
    • (1999) Antiviral Res. , vol.41 , pp. 57-64
    • Brooks, T.J.G.1    Phillpotts, R.J.2
  • 4
    • 0030801240 scopus 로고    scopus 로고
    • Interleukin-12 exhibits potent antiviral activity in experimental herpesvirus infections
    • Carr, J. A., J. Rogerson, M. J. Mulqueen. N. A. Roberts, and R. F. Booth. 1997. Interleukin-12 exhibits potent antiviral activity in experimental herpesvirus infections. J. Virol. 71:7799-7803.
    • (1997) J. Virol. , vol.71 , pp. 7799-7803
    • Carr, J.A.1    Rogerson, J.2    Mulqueen, M.J.3    Roberts, N.A.4    Booth, R.F.5
  • 5
    • 0031575538 scopus 로고    scopus 로고
    • Mucosal immunity induced by parenteral immunisation with a live attenuated Venezuelan equine encephalitis virus vaccine candidate
    • Charles, P. C., K. W. Brown, N. L. Davis, M. K. Hart, and R. E. Johnston. 1997. Mucosal immunity induced by parenteral immunisation with a live attenuated Venezuelan equine encephalitis virus vaccine candidate. Virology 228:153-160.
    • (1997) Virology , vol.228 , pp. 153-160
    • Charles, P.C.1    Brown, K.W.2    Davis, N.L.3    Hart, M.K.4    Johnston, R.E.5
  • 6
    • 0033583516 scopus 로고    scopus 로고
    • Two roads diverged: Interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection
    • Coussens, L. P., R. Peterson, S. Hsu, A. Dorner, J. D. Altman, and C. A. Biron. 1999. Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection. J. Exp. Med. 189:1315-1328.
    • (1999) J. Exp. Med. , vol.189 , pp. 1315-1328
    • Coussens, L.P.1    Peterson, R.2    Hsu, S.3    Dorner, A.4    Altman, J.D.5    Biron, C.A.6
  • 8
    • 0030586559 scopus 로고    scopus 로고
    • Rhinovirus produces non-specific activation of lymphocytes through a monocyte-dependent mechanism
    • Gern, J. E., R. Vritis, E. A. B. Kelly, E. C. Dick, and W. W. Busse. 1996. Rhinovirus produces non-specific activation of lymphocytes through a monocyte-dependent mechanism. J. Immunol. 157:1605-1612.
    • (1996) J. Immunol. , vol.157 , pp. 1605-1612
    • Gern, J.E.1    Vritis, R.2    Kelly, E.A.B.3    Dick, E.C.4    Busse, W.W.5
  • 9
    • 0026649827 scopus 로고
    • Different sensitivity to interleukin 4 of interleukin 2 and interferon alpha-induced CD69 expression in human resting NK cells and CD3+, CD4-, CD8-lymphocytes
    • Gerosa, F., M. Tomassi, G. Garra, G. Gandini, G. Tridente, and C. Benati. 1992. Different sensitivity to interleukin 4 of interleukin 2 and interferon alpha-induced CD69 expression in human resting NK cells and CD3+, CD4-, CD8-lymphocytes. Cell. Immunol. 141:342-351.
    • (1992) Cell. Immunol. , vol.141 , pp. 342-351
    • Gerosa, F.1    Tomassi, M.2    Garra, G.3    Gandini, G.4    Tridente, G.5    Benati, C.6
  • 10
    • 0032145655 scopus 로고    scopus 로고
    • Induction of protective immune responses against Venezuelan equine encephalitis (VEE) virus aerosol challenge with microencapsulated VEE virus vaccine
    • Greenway, T. E., J. H. Eldridge, G. Ludwig, J. K. Staas, J. F. Smith, R. M. Gilley, and S. M. Michalek. 1998. Induction of protective immune responses against Venezuelan equine encephalitis (VEE) virus aerosol challenge with microencapsulated VEE virus vaccine. Vaccine 16:1314-1323.
    • (1998) Vaccine , vol.16 , pp. 1314-1323
    • Greenway, T.E.1    Eldridge, J.H.2    Ludwig, G.3    Staas, J.K.4    Smith, J.F.5    Gilley, R.M.6    Michalek, S.M.7
  • 11
    • 0030874438 scopus 로고    scopus 로고
    • Kinetics of cytokine expression and regulation of host protection following infection with molecularly cloned Venezuelan equine encephalitis virus
    • Grieder, F. B., B. K. Davis, X. D. Zhou, S. J. Chen, F. D. Finkelman, and W. C. Gause. 1997. Kinetics of cytokine expression and regulation of host protection following infection with molecularly cloned Venezuelan equine encephalitis virus. Virology 233:302-312.
    • (1997) Virology , vol.233 , pp. 302-312
    • Grieder, F.B.1    Davis, B.K.2    Zhou, X.D.3    Chen, S.J.4    Finkelman, F.D.5    Gause, W.C.6
  • 12
    • 0028895608 scopus 로고
    • Specific restrictions in the progression of Venezuelan equine encephalitis virus-induced disease resulting from single amino acid changes in the glycoproteins
    • Grieder, F. B., N. L. Davis, J. F. Aronson, P. C. Charles, D. C. Sellon, K. Suzuki, and R. E. Johnston. 1995. Specific restrictions in the progression of Venezuelan equine encephalitis virus-induced disease resulting from single amino acid changes in the glycoproteins. Virology 206:994-1006.
    • (1995) Virology , vol.206 , pp. 994-1006
    • Grieder, F.B.1    Davis, N.L.2    Aronson, J.F.3    Charles, P.C.4    Sellon, D.C.5    Suzuki, K.6    Johnston, R.E.7
  • 13
    • 0030218898 scopus 로고    scopus 로고
    • Virulent and attenuated mutant Venezuelan equine encephalitis virus show marked differences in replication in infection in murine macrophages
    • Grieder, F. B., and H. T. Nguyen. 1996. Virulent and attenuated mutant Venezuelan equine encephalitis virus show marked differences in replication in infection in murine macrophages. Microb. Pathog. 21:85-95.
    • (1996) Microb. Pathog. , vol.21 , pp. 85-95
    • Grieder, F.B.1    Nguyen, H.T.2
  • 14
    • 0033602581 scopus 로고    scopus 로고
    • Role of interferon and interferon regulatory factors in early protection against Venezuelan equine encephalitis virus infection
    • Grieder, F. B., and S. N. Vogel. 1999. Role of interferon and interferon regulatory factors in early protection against Venezuelan equine encephalitis virus infection. Virology 257:106-118.
    • (1999) Virology , vol.257 , pp. 106-118
    • Grieder, F.B.1    Vogel, S.N.2
  • 15
    • 0025334993 scopus 로고
    • Protection against lethal Venezuelan equine encephalitis (VEE) virus infection by cell-free supernatant obtained from immune spleen cells
    • Huprikar, J., M. C. Dal Canto, and S. G. Rabinowitz. 1990. Protection against lethal Venezuelan equine encephalitis (VEE) virus infection by cell-free supernatant obtained from immune spleen cells. J. Neurol. Sci. 97:143-153.
    • (1990) J. Neurol. Sci. , vol.97 , pp. 143-153
    • Huprikar, J.1    Dal Canto, M.C.2    Rabinowitz, S.G.3
  • 16
    • 0027465503 scopus 로고
    • Cell surface glycoproteins expressed on activated human T cells induce production of interleukin-1 beta by monocytic cells: A possible role of CD69
    • Isler, P., E. Vey, J. H. Zhang, and J. M. Dayer. 1993. Cell surface glycoproteins expressed on activated human T cells induce production of interleukin-1 beta by monocytic cells: a possible role of CD69. Eur. Cytokine Netw. 4:15-23.
    • (1993) Eur. Cytokine Netw. , vol.4 , pp. 15-23
    • Isler, P.1    Vey, E.2    Zhang, J.H.3    Dayer, J.M.4
  • 17
    • 0026214160 scopus 로고
    • Pathogenesis of Venezuelan equine encephalitis virus infection in mice and hamsters
    • Jackson, A. C., S. K. SenGupta, and J. F. Smith. 1991. Pathogenesis of Venezuelan equine encephalitis virus infection in mice and hamsters. Vet. Pathol. 28:410-418.
    • (1991) Vet. Pathol. , vol.28 , pp. 410-418
    • Jackson, A.C.1    SenGupta, S.K.2    Smith, J.F.3
  • 18
    • 0000113157 scopus 로고
    • Alphaviruses
    • B. N. Fields, D. M. Knipe, P. M. Howley, R. M. Chanock, J. L. Melnick, T. P. Monath, B. Roizman, and S. E. Strauss (ed.), Lippincott-Raven, Philadelphia, Pa.
    • Johnston, R. E., and C. J. Peters. 1995. Alphaviruses, p. 843-898. In B. N. Fields, D. M. Knipe, P. M. Howley, R. M. Chanock, J. L. Melnick, T. P. Monath, B. Roizman, and S. E. Strauss (ed.), Fields virology, 3rd ed. Lippincott-Raven, Philadelphia, Pa.
    • (1995) Fields Virology, 3rd Ed. , pp. 843-898
    • Johnston, R.E.1    Peters, C.J.2
  • 19
    • 0001365675 scopus 로고
    • Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model
    • Katre, N. V., M. J. Knauf, and W. J. Laird. 1987. Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model. Proc. Natl Acad. Sci. USA 84:1487-1491.
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 1487-1491
    • Katre, N.V.1    Knauf, M.J.2    Laird, W.J.3
  • 20
    • 0030928503 scopus 로고    scopus 로고
    • Interleukin-12 promotes recovery from viral encephalitis
    • Komatsu, T., M. Barna, and C. S. Reiss. 1997. Interleukin-12 promotes recovery from viral encephalitis. Viral Immunol. 10:35-47.
    • (1997) Viral Immunol. , vol.10 , pp. 35-47
    • Komatsu, T.1    Barna, M.2    Reiss, C.S.3
  • 21
    • 0024601569 scopus 로고
    • Macrophage activation for cytolysis of virally infected target cells
    • LeBlanc, P. A. 1989. Macrophage activation for cytolysis of virally infected target cells. J. Leukoc. Biol. 45:345-352.
    • (1989) J. Leukoc. Biol. , vol.45 , pp. 345-352
    • LeBlanc, P.A.1
  • 22
    • 0001503752 scopus 로고
    • Human infection with Venezuelan equine encephalomyelitis virus
    • Lennette, E. H., and H. Koprowski. 1943. Human infection with Venezuelan equine encephalomyelitis virus. JAMA 123:1088-1095.
    • (1943) JAMA , vol.123 , pp. 1088-1095
    • Lennette, E.H.1    Koprowski, H.2
  • 23
    • 0027512561 scopus 로고
    • CD3-stimulated Jurkat T cells mediate IL-I beta production in monocytic THP-1 cells: Role of LFA-1 molecule and participation of CD69 T cell antigen
    • Manie, S., J. Kubar, M. Limouse, B. Ferrua, M. Ticchioni, J. P. Breittmayer, J. F. Peyron, L. Schaffar, and B. Rossi. 1993. CD3-stimulated Jurkat T cells mediate IL-I beta production in monocytic THP-1 cells: role of LFA-1 molecule and participation of CD69 T cell antigen. Eur. Cytokine Netw. 4:7-13.
    • (1993) Eur. Cytokine Netw. , vol.4 , pp. 7-13
    • Manie, S.1    Kubar, J.2    Limouse, M.3    Ferrua, B.4    Ticchioni, M.5    Breittmayer, J.P.6    Peyron, J.F.7    Schaffar, L.8    Rossi, B.9
  • 24
    • 0028266819 scopus 로고
    • Effects of IL-12 on the response and susceptibility of experimental viral infections
    • Orange, J. S., S. F. Wolf, and C. A. Biron. 1994. Effects of IL-12 on the response and susceptibility of experimental viral infections. J. Immunol. 152:1253-1264.
    • (1994) J. Immunol. , vol.152 , pp. 1253-1264
    • Orange, J.S.1    Wolf, S.F.2    Biron, C.A.3
  • 25
    • 0038656827 scopus 로고
    • Venezuelan encephalitis
    • Pan American Health Organization, Washington, D.C.
    • Pan American Health Organization. 1972. Venezuelan encephalitis, p. 7-16. In Proceedings of the Workshop. Symposium on Venezuelan encephalitis virus. Pan American Health Organization, Washington, D.C.
    • (1972) Proceedings of the Workshop. Symposium on Venezuelan Encephalitis Virus , pp. 7-16
  • 26
    • 0001693601 scopus 로고
    • Alphaviruses
    • B. N. Fields and D. M. Knipe (ed.), Raven Press, New York, N.Y.
    • Peters, C. J., and J. M. Dalrymple. 1990. Alphaviruses, p. 713-761. In B. N. Fields and D. M. Knipe (ed.), Virology. Raven Press, New York, N.Y.
    • (1990) Virology , pp. 713-761
    • Peters, C.J.1    Dalrymple, J.M.2
  • 27
    • 0031050547 scopus 로고    scopus 로고
    • A simple device for the exposure of animals to infectious microorganisms by the airborne route
    • Phillpotts, R. J., T. J. G. Brooks, and C. S. Cox. 1997. A simple device for the exposure of animals to infectious microorganisms by the airborne route. Epidemiol. Infect. 118:71-75.
    • (1997) Epidemiol. Infect. , vol.118 , pp. 71-75
    • Phillpotts, R.J.1    Brooks, T.J.G.2    Cox, C.S.3
  • 28
    • 0033605098 scopus 로고    scopus 로고
    • TC-83 vaccine protects against airborne or subcutaneous challenge with heterologous mouse-virulent strains of Venezuelan equine encephalitis virus
    • Phillpotts, R. J., and A. J. Wright. 1999. TC-83 vaccine protects against airborne or subcutaneous challenge with heterologous mouse-virulent strains of Venezuelan equine encephalitis virus. Vaccine 17:982-988.
    • (1999) Vaccine , vol.17 , pp. 982-988
    • Phillpotts, R.J.1    Wright, A.J.2
  • 29
    • 0029960102 scopus 로고    scopus 로고
    • Long-term duration of delectable neutralizing antibodies after administration of live-attenuated VEE vaccine and following booster vaccination with inactivated VEE vaccine
    • Pittman, P. R., R. S. Makuch, J. A. Mangiafico, T. L. Cannon, P. H. Gibbs, and C. J. Peters. 1996. Long-term duration of delectable neutralizing antibodies after administration of live-attenuated VEE vaccine and following booster vaccination with inactivated VEE vaccine. Vaccine 14:337-343.
    • (1996) Vaccine , vol.14 , pp. 337-343
    • Pittman, P.R.1    Makuch, R.S.2    Mangiafico, J.A.3    Cannon, T.L.4    Gibbs, P.H.5    Peters, C.J.6
  • 30
    • 0029973267 scopus 로고    scopus 로고
    • Polyethylene glycol-modified interleukin-2 and thymosin alpha 1 in human immunodeficiency virus type 1 infection
    • Ramachandran, R., D. A, Katzenstein, M. A. Winters, S. K. Kundu, and T. C. Merigan. 1996. Polyethylene glycol-modified interleukin-2 and thymosin alpha 1 in human immunodeficiency virus type 1 infection. J. Infect. Dis. 173:1005-1008.
    • (1996) J. Infect. Dis. , vol.173 , pp. 1005-1008
    • Ramachandran, R.1    Katzenstein, D.A.2    Winters, M.A.3    Kundu, S.K.4    Merigan, T.C.5
  • 31
    • 0020064191 scopus 로고
    • Antigenic analysis of the surface glycoproteins of a Venezuelan equine encephalomyelitis virus (TC-83) using monoclonal antibodies
    • Roehrig, J. T., J. W. Day, and R. M. Kinney. 1982. Antigenic analysis of the surface glycoproteins of a Venezuelan equine encephalomyelitis virus (TC-83) using monoclonal antibodies. Virology 118:269-278.
    • (1982) Virology , vol.118 , pp. 269-278
    • Roehrig, J.T.1    Day, J.W.2    Kinney, R.M.3
  • 32
    • 0026366078 scopus 로고
    • Venezuelan equine encephalitis virus propagation in the olfactory tract of normal and immunized mice
    • Ryzhikov, A. B., N. V. Tkacheva, A. N. Sergeev, and E. I. Ryabchikova. 1991. Venezuelan equine encephalitis virus propagation in the olfactory tract of normal and immunized mice. Biomed. Sci. 2:607-614.
    • (1991) Biomed. Sci. , vol.2 , pp. 607-614
    • Ryzhikov, A.B.1    Tkacheva, N.V.2    Sergeev, A.N.3    Ryabchikova, E.I.4
  • 33
    • 0025739093 scopus 로고
    • Antiviral actions of interferon, interferon-regulated cellular proteins and their surprisingly selective antiviral activities
    • Samuel, C. E. 1991. Antiviral actions of interferon, interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Virology 183:1-11.
    • (1991) Virology , vol.183 , pp. 1-11
    • Samuel, C.E.1
  • 34
    • 0031774383 scopus 로고    scopus 로고
    • Resistance to alpha/beta interferons correlates with the epizootic and virulence potential of Venezuelan equine encephalitis viruses and is determined by the 5′ noncoding region and glycoproteins
    • Spotts, D. R., R. M. Reich, M. A. Kalkhan, R. M. Kinney, and J. T. Roehrig. 1998. Resistance to alpha/beta interferons correlates with the epizootic and virulence potential of Venezuelan equine encephalitis viruses and is determined by the 5′ noncoding region and glycoproteins. J Virol. 72:10286-10291.
    • (1998) J Virol. , vol.72 , pp. 10286-10291
    • Spotts, D.R.1    Reich, R.M.2    Kalkhan, M.A.3    Kinney, R.M.4    Roehrig, J.T.5
  • 35
    • 0032433054 scopus 로고    scopus 로고
    • Type 1 interferon-mediated stimulation of T cells by CpG DNA
    • Sun, S., X. Zhang, D. F. Tough, and J. Sprent. 1998. Type 1 interferon-mediated stimulation of T cells by CpG DNA. J. Exp. Med. 188:2335-2342.
    • (1998) J. Exp. Med. , vol.188 , pp. 2335-2342
    • Sun, S.1    Zhang, X.2    Tough, D.F.3    Sprent, J.4
  • 36
    • 0027401244 scopus 로고
    • Prolonged immunostimulatory effect of low-dose polyethylene glycol interleukin 2 in patients with human immunodeficiency virus type 1 infection
    • Teppler, H., G. Kaplan, K. A. Smith, A. L. Montana, P. Meyn, and Z. A. Cohn. 1993. Prolonged immunostimulatory effect of low-dose polyethylene glycol interleukin 2 in patients with human immunodeficiency virus type 1 infection. J. Exp. Med. 177:483-492.
    • (1993) J. Exp. Med. , vol.177 , pp. 483-492
    • Teppler, H.1    Kaplan, G.2    Smith, K.A.3    Montana, A.L.4    Meyn, P.5    Cohn, Z.A.6
  • 37
    • 0024390970 scopus 로고
    • T cell activation via Leu-23 (CD69)
    • Testi, R., J. H. Phillips, and L. L. Lanier. 1989. T cell activation via Leu-23 (CD69). J. Immunol. 143:1123-1128.
    • (1989) J. Immunol. , vol.143 , pp. 1123-1128
    • Testi, R.1    Phillips, J.H.2    Lanier, L.L.3
  • 38
    • 0030438699 scopus 로고    scopus 로고
    • Molecular design of hybrid tumour necrosis factor-alpha III: Polyethylene glycol-modified tumour necrosis factor-alpha has markedly enhanced antitumour potency due to longer plasma half-life and higher tumour accumulation
    • Tsutsumi, Y., T. Kihira, S. Tsunoda, H. Kamada, S. Nakagawa, Y. Kaneda, T. Kanamori, and T. Mayumi. 1996. Molecular design of hybrid tumour necrosis factor-alpha III: polyethylene glycol-modified tumour necrosis factor-alpha has markedly enhanced antitumour potency due to longer plasma half-life and higher tumour accumulation. J. Pharmacol. Exp. Ther. 278: 1006-1011.
    • (1996) J. Pharmacol. Exp. Ther. , vol.278 , pp. 1006-1011
    • Tsutsumi, Y.1    Kihira, T.2    Tsunoda, S.3    Kamada, H.4    Nakagawa, S.5    Kaneda, Y.6    Kanamori, T.7    Mayumi, T.8
  • 39
    • 0030053528 scopus 로고    scopus 로고
    • Role of monocytes in the up-regulation of the early activation marker CD69 on B and T murine lymphocytes induced by microbial mitogens
    • Vilanova, M., D. Tavares, P. Ferreira, L. Oliveira, A. Nobrega, R. Appelberg, and M. Arala-Chaves. 1996. Role of monocytes in the up-regulation of the early activation marker CD69 on B and T murine lymphocytes induced by microbial mitogens. Scand. J. Immunol. 43:155-163.
    • (1996) Scand. J. Immunol. , vol.43 , pp. 155-163
    • Vilanova, M.1    Tavares, D.2    Ferreira, P.3    Oliveira, L.4    Nobrega, A.5    Appelberg, R.6    Arala-Chaves, M.7
  • 40
    • 0030059236 scopus 로고    scopus 로고
    • Venezuelan equine encephalitis in BALB/c mice: Kinetic analysis of central nervous system infection following aerosol or subcutaneous inoculation
    • Vogel, P., D. Abplanalp, W. Kell, M. S. Ibrahim, M. B. Downs, W. D. Pratt, and K. J. Davis. 1996. Venezuelan equine encephalitis in BALB/c mice: kinetic analysis of central nervous system infection following aerosol or subcutaneous inoculation. Arch. Pathol. Lab. Med. 120:164-172.
    • (1996) Arch. Pathol. Lab. Med. , vol.120 , pp. 164-172
    • Vogel, P.1    Abplanalp, D.2    Kell, W.3    Ibrahim, M.S.4    Downs, M.B.5    Pratt, W.D.6    Davis, K.J.7
  • 41
    • 0009312259 scopus 로고    scopus 로고
    • Humane endpoints are an objective measure of morbidity in Venezuelan encephalomyelitis virus infection in mice
    • Wright, A. W., and R. J. Phillpotts. 1998. Humane endpoints are an objective measure of morbidity in Venezuelan encephalomyelitis virus infection in mice. Arch. Virol. 141:71-75.
    • (1998) Arch. Virol. , vol.141 , pp. 71-75
    • Wright, A.W.1    Phillpotts, R.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.