Dentin matrix protein 1 and dentin sialophosphoprotein in human sound and carious teeth: An immunohistochemical and colorimetric assay

European Journal of Histochemistry

Volumn 57, Issue 4, 2013, Pages 217-224

  Martini, D ^a   Trire A ^a   Breschi, L ^b,c   Mazzoni, A ^b,c   Orsini, G ^d   Teti, G ^a   Falconi, M ^a   Ruggeri Jr , Alessandra ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^d UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

Author keywords

Dentin matrix protein; Dentin sialophosphoprotein; Immunohistochemistry; Sclerotic dentin

Indexed keywords

DENTIN SIALOPHOSPHOPROTEIN; DMP1 PROTEIN, HUMAN; PHOSPHOPROTEIN; SCLEROPROTEIN; SIALOGLYCOPROTEIN;

ARTICLE; BIOSYNTHESIS; COLORIMETRY; DENTAL CARIES; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; ODONTOBLAST; PATHOLOGY; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

COLORIMETRY; DENTAL CARIES; EXTRACELLULAR MATRIX PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; ODONTOBLASTS; PHOSPHOPROTEINS; SIALOGLYCOPROTEINS;

EID: 84887133657     PISSN: 1121760X     EISSN: None     Source Type: Journal    
DOI: 10.4081/ejh.2013.e32     Document Type: Article

References (48)

1. Fisher LW, Torchia DA, Fohr B, Young MF, Fedarko NS. Flexible structures of SIBLING proteins, bone sialoprotein, and osteopontin. Biochem Biophys Res Commun 2001;280:460-5.
2. Qin C, Baba O, Butler WT. Post-translational modifications of sibling proteins and their roles in osteogenesis and dentinogenesis. Crit Rev Oral Biol Med 2004;15:126-36.
3. Orsini G, Ruggeri A, Mazzoni A, Nato F, Falconi M, Putignano A, et al. Immunohistochemical localization of dentin matrix protein 1 in human dentin. Eur J Histochem 2008;52:215-20.
4. Deshpande AS, Fang PA, Zhang X, Jayaraman T, Sfeir C, Beniash E. Primary structure and phosphorylation of dentin matrix protein 1 (DMP1) and dentin phosphophoryn (DPP) uniquely determine their role in biomineralization. Bioma-cromolecules 2011;12:2933-45.
5. Goldberg M, Smith AJ. Cells and extracellular matrices of dentin and pulp: a biological basis for repair and tissue engineering. Crit Rev Oral Biol Med 2004;15:13-27.
6. Narayanan K, Srinivas R, Ramachandran A, Hao J, Quinn B, George A. Differen-tiation of embryonic mesenchymal cells to odontoblast-like cells by overexpression of dentin matrix protein 1. Proc Natl Acad Sci USA 2001;98:4516-21.
7. Ye L, MacDougall M, Zhang S, Xie Y, Zhang J, Li Z, et al. Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. J Biol Chem 2004;279:19141-8.
8. Lu Y, Ye L, Yu S, Zhang S, Xie Y, McKee MD, et al. Rescue of odontogenesis in Dmp1-deficient mice by targeted reexpression of DMP1 reveals roles for DMP1 in early odontogenesis and dentin apposition in vivo. Dev Biol 2007;303:191-201.
9. Turan S, Aydin C, Bereket A, Akcay T, Güran T, Yaralioglu BA, et al. Identification of a novel dentin matrix protein-1 (DMP-1) mutation and dental anomalies in a kindred with autosomal recessive hypophosphatemia. Bone 2010;46:402-9.
10. Qin C, Brunn JC, Cook RG, Orkiszewski RS, Malone JP, Veis A, et al. Evidence for the proteolytic processing of dentin matrix protein 1: identification and characterization of processed fragments and cleavage sites. J Biol Chem 2003;278:34700-8.
11. Huang B, Sun Y, Maciejewska I, Qin D, Peng T, McIntyre B, et al. Distribution of SIBLING proteins in the organic and inorganic phases of rat dentin and bone. Eur J Oral Sci 2008;116:104-12.
12. Sun Y, Lu Y, Chen L, Gao T, D'Souza R, Feng JQ, et al. DMP1 processing is essential to dentin and jaw formation. J Dent Res 2011;90:619-24.
13. Boskey AL. Biomineralization: an overview. Connec Tissue Res 2003;44 (Suppl.1):5-9.
14. Boskey A, Spevak L, Tan M, Doty SB, Butler WT. Dentin sialoprotein (DSP) has limited effects on in vitro apatite formation and growth. Calcif Tissue Int 2000;67:472-8.
15. Suzuki S, Sreenath T, Haruyama N, Honeycutt C, Terse A, Cho A, et al. Dentin sialoprotein and dentin phosphoprotein have distinct roles in dentin mineralization. Matrix Biol 2009;28:221-9.
16. Prasad M, Butler WT, Qin C. Dentin sialophosphoprotein in biomineralization. Connect Tissue Res 2010;51:404-17.
17. Sreenath T, Thyagarajan T, Hall B, Longenecker G, D'Souza R, Hong S, et al. Dentin sialophosphoprotein knockout mouse teeth display widened predentin zone and develop defective dentin mineralization similar to human dentinogenesis imperfecta type III. J Biol Chem 2003;278: 24874-80.
18. Nanci A, Wazen R, Nishio C, Zalzal SF. Immunocytochemistry of matrix proteins in calcified tissues: functional biochemistry on section. Eur J Histochem 2008;52:201-14.
19. Holappa H, Nieminen P, Tolva L, Lukinmaa PL, Alaluusua S. Splicing site mutations in dentin sialophosphoprotein causing dentinogenesis imperfecta type II. Eur J Oral Sci 2006;114:381-4.
20. Kim JW, Nam SH, Jang KT, Lee SH, Kim CC, Hahn SH, et al. A novel splice acceptor mutation in the DSPP gene causing dentinogenesis imperfecta type II. Hum Genet 2004;115:248-54.
21. Dong J, Gu T, Jeffords L, MacDougall M. Dentin phosphoprotein compound mutation in dentin sialophosphoprotein causes dentinogenesis imperfecta type III. Am J Med Genet A 2005;132A:305-9.
22. Feng JQ, Luan X, Wallace J, Jing D, Ohshima T, Kulkarni AB, et al. Genomic organization, chromosomal mapping, and promoter analysis of the mouse dentin sialophosphoprotein (Dspp) gene, which codes for both dentin sialoprotein and dentin phosphoprotein. J Biol Chem 1998;273:9457-64.
23. George A, Srinivasan RSR, Liu K, Veis A. Rat dentin matrix protein 3 is a compound protein of rat dentin sialoprotein and phosphophoryn. Connect Tissue Res 1999; 40: 49-57.
24. Ritchie HH, Ritchie DG, Wang LH. Six decades of dentinogenesis research. Historical and prospective views on phosphophoryn and dentin sialoprotein. Eur J Oral Sci 1998;106(Suppl.1):211-20.
25. MacDougall M, Zeichner-David M, Slavkin HC. Production and characterization of antibodies against murine dentine phosphoprotein. Biochem J 1985;1232:493-500.
26. Weinstock M, Leblond CP. Radioauto-graphic visualization of the deposition of a phosphoprotein at the mineralization front in the dentin of the rat incisor. J Cell Biol 1973;56:838-45.
27. Stetler-Stevenson WG, Veis A. Type I collagen shows a specific binding affinity for bovine dentin phosphophoryn. Calcif Tissue Int 1986;38:135-41.
28. Orsini G, Ruggeri A, Mazzoni A, Nato F, Falconi M, Putignano A, et al. Immunohi-stochemical localization of dentin matrix protein 1 in human dentin. Eur J Histochem 2008;52:215-20.
29. Ruggeri A, Orsini G, Mazzoni A, Nato F, Papa V, Piccirilli M, et al. Immunohi-stochemical and biochemical assay of versican in human sound predentine/dentine matrix. Eur J Histochem 2009;23;53:125-33.
30. Orsini G, Ruggeri A Jr, Mazzoni A, Papa V, Mazzotti G, Di Lenarda R, et al. Immunohistochemical identification of decorin and biglycan in human dentin: a correlative field emission scanning electron microscopy/transmission electron microscopy study. Calcif Tissue Int 2007;81:39-45.
31. Breschi L, Lopes M, Gobbi P, Mazzotti G, Falconi M, Perdigão J. Dentin proteoglycans: an immunocytochemical FEISEM study. J Biomed Mater Res 2002;61:40-6.
32. Mazzoni A, Mannello F, Tay FR, Tonti GA, Papa S, Mazzotti G, et al. Zymographic analysis and characterization of MMP-2 and-9 forms in human sound dentin. J Dent Res 2007;86:436-40.
33. Weber DF. Human dentine sclerosis: a microradiographic survey. Arch Oral Biol 1974;19:163-9.
34. Blake GC. The peritubular zones in human dentin. Br Dent J 1958;104:57-64.
35. Arnold WH, Konopka S, Kriwalsky MS, Gaengler P. Morphological analysis and chemical content of natural dentin carious lesion zones. Ann Anat 2003;185:419-24.
36. Vahl J, Höhling HJ, Frank RM. Elektronen-strahlbeugung an rhomboedrisch aussehenden Mineralbildungen in kariösem Dentin. Arch Oral Biol 1969;9:315-20.
37. Daculsi G, LeGeros RZ, Jean A, Kerebel B. Possible physico-chemical processes in human dentin caries. J Dent Res 1987;66: 1356-9.
38. Riccio M, Resca E, Maraldi T, Pisciotta A, Ferrari A, Bruzzesi G. et al. Human dental pulp stem cells produce mineralized matrix in 2D and 3D cultures. Eur J Histochem 2010;54:e46.
39. Schroeder HE. [Orale Strukturbiologie]. [Book in German]. Thieme Ed., Stuttgart, Germany, 1992.
40. Arnold WH, Konopka S, Gaengler P. Qualitative and quantitative assessment of intratubular dentin formation in human natural carious lesions. Calcif Tissue Int 2001;69:268-73.
41. Teti G, Salvatore V, Ruggeri A, Manzoli L, Gesi M, Orsini G, et al. In vitro reparative dentin: a biochemical and morphological study. Eur J Histochem 2013;57:e23.
42. Tabatabaei FS, Ai J, Jafarzadeh Kashi TS, Khazaei M, Kajbafzadeh AM, Ghanbari Z. Effect of dentine matrix proteins on human endometrial adult stem-like cells: in vitro regeneration of odontoblasts cells. Arch Oral Biol 2013;58:871-9.
43. Li Y, Lü X, Sun X, Bai S, Li S, Shi J. Odonto-blast-like cell differentiation and dentin formation induced with TGF-1. Arch Oral Biol 2011;56:1221-9.
44. Brännström M, Lind PO. Pulpal response to early dental caries. J Dent Res 1965;44: 1045-50.
45. Bjørndal L, Darvann T, Thylstrup A. A quantitative light microscopic study of the odontoblast and subodontoblastic reactions to active and arrested enamel caries without cavitation. Caries Res 1998;32:59-69.
46. Pashley DH. The influence of dentin permeability and pulpal blood flow on pulpal solute concentrations. J Endod 1979;5:355-61.
47. Pashley DH. Dynamics of the pulpo-dentin complex. Crit Rev Oral Biol Med 1996;7: 104-33.
48. Yoshiba K, Yoshiba N, Ejiri S, Iwaku M, Ozawa H. Odontoblast processes in human dentin revealed by fluorescence labeling and transmission electron microscopy. Histochem Cell Biol 2002;118:205-12.