Genetic rescue of Muenke syndrome model hearing loss reveals prolonged FGF-dependent plasticity in cochlear supporting cell fates

Genes and Development

Volumn 27, Issue 21, 2013, Pages 2320-2331

  Mansour, Suzanne L ^a   Li, Chaoying ^a   Urness, Lisa D ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Cell fate transformation; Deiters' cell; FGF10; FGFR3 P244R; Mouse; Pillar cell

Indexed keywords

FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 10; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 3; HERMES ANTIGEN;

ARTICLE; BASILAR MEMBRANE; CELL DIFFERENTIATION; CELL FATE; COCHLEAR NERVE; GENE EXPRESSION; GENE MUTATION; GENOTYPE; HAIR CELL; HEARING IMPAIRMENT; HETEROZYGOSITY; HETEROZYGOTE; HOMOZYGOTE; IMMUNOREACTIVITY; MUENKE SYNDROME; NERVE CELL PLASTICITY; PHENOTYPE; PRIORITY JOURNAL; WILD TYPE;

CELL FATE TRANSFORMATION; DEITERS' CELL; FGF10; FGFR3 P244R; MOUSE; PILLAR CELL;

ANIMALS; CELL DIFFERENTIATION; COCHLEA; CRANIOSYNOSTOSES; DISEASE MODELS, ANIMAL; FIBROBLAST GROWTH FACTORS; GENE DOSAGE; HAIR CELLS, AUDITORY; HEARING LOSS; MICE; SIGNAL TRANSDUCTION;

EID: 84887126009     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.228957.113     Document Type: Article

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