CD44 is a marker for the outer pillar cells in the early postnatal mouse inner ear

JARO - Journal of the Association for Research in Otolaryngology

Volumn 11, Issue 3, 2010, Pages 407-418

  Hertzano, Ronna ^a   Puligilla, Chandrakala ^b   Chan, Siaw Lin ^a   Timothy, Caroline ^a   Depireux, Didier A ^c   Ahmed, Zubair ^d,e   Wolf, Jeffrey ^a   Eisenman, David J ^a   Friedman, Thomas B ^f   Riazuddin, Sheikh ^g   Kelley, Matthew W ^b   Strome, Scott E ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

^d CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^f NATIONAL INSTITUTES OF HEALTH   (United States)

^g UNIVERSITY OF THE PUNJAB   (Pakistan)

Author keywords

CD44; Cochlea; Deafness; FGFR3; Outer pillar cells

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 3; HERMES ANTIGEN; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; AUDITORY SYSTEM; CELL MATURATION; COCHLEA; CONTROLLED STUDY; GENE SEQUENCE; HEARING IMPAIRMENT; IMMUNOHISTOCHEMISTRY; INNER EAR; KNOCKOUT MOUSE; MOUSE; MOUSE STRAIN; NEWBORN; NONHUMAN; OPEN READING FRAME; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SACCULUS; UTRICLE;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD44; BIOLOGICAL MARKERS; DEAFNESS; EAR, INNER; GENE EXPRESSION PROFILING; HEARING; HUMANS; LABYRINTH SUPPORTING CELLS; MICE; MICE, KNOCKOUT; PROTEIN ISOFORMS; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 78650195911     PISSN: 15253961     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10162-010-0211-x     Document Type: Article

References (41)

1. AHMED ZM, RIAZUDDIN S, BERNSTEIN SL, AHMED Z, KHAN S, GRIFFITH AJ, MORELL RJ, FRIEDMAN TB, WILCOX ER (2001.) Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F. Am J Hum Genet 69: 25-34
2. ARUFEO A, SIAMENKOVIC I, MELNICK M, UNDERBILL CB, SEED B (1990) CD44 is the principal cell surface receptor for hyaluronate. Cell 61: 1303-1313
3. BEARE A, STOCKINGER H, ZOLA H, NICHOLSON I (2008) Monoclonal antibodies to human cell surface antigens. Curr Protoč Immunol Appendix 4:4A
4. BELYANTSEVA IA, ADLER HJ, CURI R, FROLENKOV GI, KACHAR B (2000) Expression and localization of prestin and the sugar transporter GLUTS during development of electromotility in cochlear outer hair cells. J Neurosa 20: RC116
5. BOURGUIGNON IY (2008) Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression. Semin Cancer Biol 18: 251-259
6. COLVINJS, BOHNE BA, HARDING GW, McEWEN DG, ORNITZ DM (1996) Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nat Genet 12: 390-397
7. DABDOUB A, PULIGILLA C, JONES JM, FRITZSCH B, CHEAH KS, PEVNY LH, KELLEY MW (2008) Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci USA. 105: 18396-18401.
8. DOETZLHOFER A, WHITE P, LEE YS, GROVES A, SEGIL N (2006) Prospective identification and purification of hair cell and supporting cell progenitors from the embryonic cochlea. Brain Res 1091: 282-288
9. DOETZLHOFER A, BASCH ML, OHYAMAT, GESSLER M, GROVES AK, SEGIL N (2009) Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ, of Corti. Dev Cell 16: 58-69
10. DROR AA, AVRAHAM. KB (2009) Hearing loss: mechanisms revealed by genetics and cell biology. Annu Rev Genet 43: 411-437
11. FORGE A, WRIGHT T (2002) The molecular architecture of the inner ear. Br Med Bull 63: 5-24
12. GOODISON S, URQUIDI V, TARIN D (1999) CD44 cell adhesion molecules. Mol Pathol 52: 189-196
13. HASSON T, HEINTZELMAN MB, SANTOS-SACCHI J, COREY DP, MOOSEKER MS (1995) Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type IB. Proc Nad Acad Sci USA 92: 9815-9819
14. HASSON T, GILLESPIE PG, GARCIA JA, MACDONALD RB, ZHAO Y, YEE AG, MOOSEKER MS, COREY DP (1997) Unconventional myosins in inner-ear sensory epithelia. J Cell Biol 137: 1287-1307
15. HAYASHI T, CUNNINGHAM D, BERMINOHAM-MCDONOOH O (2007) Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev Dyn. 236: 525-533
16. HERTZANO R, MONTCOUQUIOL M, RASHI-ELKELES S, ELKON R, YUCEL R, FRANKEL WN, RECHAVI G, MOROY T, FRIEDMAN TB, KELLEY MW, AVRAHAM KB (2004) Transcription profiling of inner ears from Pou4f3(dd1/dd1) identifies Gfil as a target of the Pou4f3 deafness gene. Hum Mol Genet 13: 2143-2153
17. HERZENBERG LA, DE ROSA SC (2000) Monoclonal antibodies and the FACS: complementary tools for immunobiology and medicine. Immunol Today 21: 383-390
18. HUME CR, BRAIT DL, OESTERLE EC (2007) Expression of LHXS and SOX2 during mouse inner ear development. Gene Expr Patterns 7: 798-807
19. IVANOV D, DVORIANTCHIKOVA G, BARAKAT DJ, NATHANSON L, SHESTOPALOV VT (2008) Differential gene expression profiling of large and small retinal ganglion cells. J Neurosa Methods 174: 10-17
20. JOHNSON P, RUFFELL B (2009) CD44 and its role in inflammation and inflammatory diseases. Inflamm Allergy Drug Targets 8: 208-220
21. KELLEY MW (2007) Cellular commitment and differentiation in the organ of Corti. Int J Dev Biol 51: 571-583
22. Liu J, JIANG G (2006) CD44 and hematologic malignancies. Cell Mol Immunol 3: 359-365
23. LOBO MK, KARSTEN SL, GRAY M, GESCHWIND DH, YANG XW (2006) FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains. Nat Neurosa 9: 443-452
24. MANSOUR SL, TWIGG SR, FREELAND RM, WALL SA, Li C, WILKIE AO (2009) Hearing loss in a mouse model of Muenke syndrome. Hum Mol Genet 18: 43-50
25. MARSH ED, MINARGIK J, CAMPBELL K, BROOKS-KAYAI. AR, GOLDEN JA (2008) FACS-array gene expression analysis during early development of mouse telencephalic lnterneurons. Dev Neurobiol 68: 434-445
26. McKENZIE E, KRUFIN A, KELLEY MW (2004) Cellular growth and rearrangement during the development of the mammalian organ of Corti. Dev Dyn 229: 802-812
27. MONTCOUQUIOL M, CORWIN JT (2001) Intracellular signals that control cell proliferation in mammalian balance epithelia: key roles for phosphatidylinositol-3 kinase, mammalian target of rapamycin, and S6 kinases in preference to calcium, protein kinase C, and mitogenactivated protein kinase. J Neurosci 21: 570-580
28. MORRISON A, HODGETTS C., GOSSLER A, HRABE DE ANGELIS M, LEWIS J (1999) Expression of Deitai and Serrate 1 (Jaggedl) in the mouse inner ear. Mech Dev 84: 169-172
29. MUELLER KL, JACQUES BE, KELLEY MW (2002) Fibroblast growth factor signaling regulates pillar cell development in the organ of Corti. J Neurosci 22: 9368-9377
30. PANNIER S, COULOIGNER V, MESSADDEQ N, ELMALEH-BERCES M, MUNNICH A, ROMAND R, LEGEAI-MALLET L (2009) Activating FgfR3 Y367C mutation causes hearing loss and inner ear defect in a mouse model of chondrodysplasia. Biochim Biophys Acta 1792: 140-147
31. PETERS K, ORNTTZ D, WERNER S, WILLIAMS L (1993) Unique expression, pattern of the FGF receptor 3 gene during mouse organogenesis. Dev Biol 155: 423-430
32. PRDTIN U, SCHWEIGHOFEER T, JOCHUM W, HILBERGF(1999) CD44-deficient mice develop normally with changes in subpopulations and recirculation of lymphocyte subsets.J Immunol 163: 4917-4923
33. PULIGILLA C, FENG F, ISHIKAWA K, BERTUZZI S, DABDOUB A, GRIFFITH AJ, FRITZSCH B, KELLEY MW (2007) Disruption of fibroblast growdi factor receptor 3 signaling results in defects in cellular differentiation, neuronal patterning, and hearing impairment. Dev Dyn 236: 1905-1917
34. RAPHAEL Y, ALTSCHULER RA (2003) Structure and innervation of the cochlea. Brain Res Bull 60: 397-422
35. SCHMITS R, FILMUS J, GERWIN N, SENALDI G, KIEFER F, KUNDIG T, WAKEHAM A, SHAHINIAN A, CATZAVELOS C, RAK J, FURLONGER C, ZAKARIAN A, SIMARD JJ, OHASHI PS, PAIGE CJ, GUTIERREZ-RAMOS JC, MAK TW (1997) CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity. Blood 90: 2217-2233
36. SHAIKH RS, RAMZAN K, NAZLI S, SATTAR S, KHAN SN, RIAZUDDIN S, AHMED ZM, FRIEDMAN TB (2005) A new locus for nonsyndromic deafness DFN.B51 maps to chromosome 11p13-p12. Am J Med Genet 138: 392-395
37. SPRING FA, DALCHAU R, DANIELS GL, MALLINSON G, JUDSON PA, PARSONS SF, FABRE JW, ANSTEE DJ (1988) The Ina and Inb blood group antigens are located on a glycoprotein of 80, 000 MW (the CDw44 glycoprotein) whose expression is influenced by the In (Lu) gene. Immunology 64: 37-43
38. STEFANOVA I, HILGERT I, BAZILV, KRISTOFOVA H, HOREJSI V (1989) Human leucocyte surface glycoprotein CDw44 and lymphocyte homing receptor are identical molecules. Immunogenetics 29: 402-404
39. WHITE PM, DOETZLHOFER A, LEE YS, GROVES AK, SEGIL N (2006) Mammalian cochlear supporting cells can divide and transdifferentiate into hair cells. Nature 441: 984-987
40. XIANG M, GAO WQ, HASSON T, SHIN JJ (1998) Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells. Development 125: 3935-3946
41. Yu Q, TOOLE BP (1997) Common pattern of CD44 isoforms is expressed in morphogenetically active epithelia. Dev Dyn 208: 1-10