메뉴 건너뛰기




Volumn 6, Issue 11, 2013, Pages 2272-2279

The SYT-SSX fusion protein and histological epithelial differentiation in synovial sarcoma: Relationship with extracellular matrix remodeling

Author keywords

Chromosomal translocation t(X; 18)(p11.2; q11.2); E cadherin; Epithelial differentiation; Synovial sarcoma; SYT SSX1; SYT SSX2

Indexed keywords

BIOLOGICAL MARKER; CADHERIN; ONCOPROTEIN; SYT SSX FUSION PROTEIN; SYT-SSX FUSION PROTEIN;

EID: 84887103913     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (31)

References (43)
  • 2
    • 0027933151 scopus 로고
    • Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma
    • Clark J, Rocques PJ, Crew AJ, Gill S, Shipley J, Chan AM, Gusterson BA and Cooper CS. Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma. Nat Genet 1994;7:502-508.
    • (1994) Nat Genet , vol.7 , pp. 502-508
    • Clark, J.1    Rocques, P.J.2    Crew, A.J.3    Gill, S.4    Shipley, J.5    Chan, A.M.6    Gusterson, B.A.7    Cooper, C.S.8
  • 4
    • 84875727068 scopus 로고    scopus 로고
    • Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma
    • Kadoch C and Crabtree GR. Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. Cell 2013;153:71-85.
    • (2013) Cell , vol.153 , pp. 71-85
    • Kadoch, C.1    Crabtree, G.R.2
  • 8
    • 33746906998 scopus 로고    scopus 로고
    • SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by Snail and Slug. A potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma
    • Saito T, Nagai M and Ladanyi M. SYT-SSX1 and SYT-SSX2 interfere with repression of E-cadherin by Snail and Slug. A potential mechanism for aberrant mesenchymal to epithelial transition in human synovial sarcoma. Cancer Res 2006;66:6919-6927.
    • (2006) Cancer Res , vol.66 , pp. 6919-6927
    • Saito, T.1    Nagai, M.2    Ladanyi, M.3
  • 11
    • 67649887764 scopus 로고    scopus 로고
    • Prognostic implication of SYT-SSX fusion type and clinicopathological parameters for tumor-related death, recurrence, and metastasis in synovial sarcoma
    • Sun Y, Sun B, Wang J, Cai W, Zhao X, Zhang S and Hao X. Prognostic implication of SYT-SSX fusion type and clinicopathological parameters for tumor-related death, recurrence, and metastasis in synovial sarcoma. Cancer Sci 2009;100:1018-1025.
    • (2009) Cancer Sci , vol.100 , pp. 1018-1025
    • Sun, Y.1    Sun, B.2    Wang, J.3    Cai, W.4    Zhao, X.5    Zhang, S.6    Hao, X.7
  • 16
    • 0033658259 scopus 로고    scopus 로고
    • Prognostic value of the preserved expression of the E-cadherin and catenin families of adhesion molecules and of β-catenin mutation in synovial sarcoma
    • Saito T, Oda Y, Sakamoto A, Tamiya S, Kinukawa N, Hayashi K, Iwamoto Y and Tsuneyoshi M. Prognostic value of the preserved expression of the E-cadherin and catenin families of adhesion molecules and of β-catenin mutation in synovial sarcoma. J Pathol 2000;192:342-350.
    • (2000) J Pathol , vol.192 , pp. 342-350
    • Saito, T.1    Oda, Y.2    Sakamoto, A.3    Tamiya, S.4    Kinukawa, N.5    Hayashi, K.6    Iwamoto, Y.7    Tsuneyoshi, M.8
  • 17
    • 0035087088 scopus 로고    scopus 로고
    • Prognostic significance of histologic grade and nuclear expression of beta-catenin in synovial sarcoma
    • Hasegawa T, Yokoyama R, Matsuno Y, Shimoda T and Hirohashi S. Prognostic significance of histologic grade and nuclear expression of beta-catenin in synovial sarcoma. Human Pathol 2001;32:257-263.
    • (2001) Human Pathol , vol.32 , pp. 257-263
    • Hasegawa, T.1    Yokoyama, R.2    Matsuno, Y.3    Shimoda, T.4    Hirohashi, S.5
  • 18
    • 3042749705 scopus 로고    scopus 로고
    • Aberrant expression of tight junction-related proteins ZO-1, claudin-1 and occluding in synovial sarcoma:an immunohistochemical study with ultrastructural correlation
    • Billings SD, Walsh SV, Fisher C, Nusrat A, Weiss SW and Folpe AL. Aberrant expression of tight junction-related proteins ZO-1, claudin-1 and occluding in synovial sarcoma:an immunohistochemical study with ultrastructural correlation. Mod Pathol 2004;17:141-149.
    • (2004) Mod Pathol , vol.17 , pp. 141-149
    • Billings, S.D.1    Walsh, S.V.2    Fisher, C.3    Nusrat, A.4    Weiss, S.W.5    Folpe, A.L.6
  • 19
    • 0036645310 scopus 로고    scopus 로고
    • SYT-SSX is critical for cyclin D1 expression in synovial sarcoma cells:a gain of function of the t(X;18)(p11.2;q11.2) translocation
    • Xie Y, Skytting B, Nilsson G, Gasbarri A, Haslam K, Bartolazzi A, Brodin B, Mandahl N and Larsson O. SYT-SSX is critical for cyclin D1 expression in synovial sarcoma cells:a gain of function of the t(X;18)(p11.2;q11.2) translocation. Cancer Res 2002;62:3861-3867.
    • (2002) Cancer Res , vol.62 , pp. 3861-3867
    • Xie, Y.1    Skytting, B.2    Nilsson, G.3    Gasbarri, A.4    Haslam, K.5    Bartolazzi, A.6    Brodin, B.7    Mandahl, N.8    Larsson, O.9
  • 20
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions:a comparison with Snail and E47 repressors
    • Bolós V, Hector Peinado H, Pérez-Moreno MA, Fraga MF, Esteller M and Cano A. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions:a comparison with Snail and E47 repressors. J Cell Sci 2003;116:499-511.
    • (2003) J Cell Sci , vol.116 , pp. 499-511
    • Bolós, V.1    Hector Peinado, H.2    Pérez-Moreno, M.A.3    Fraga, M.F.4    Esteller, M.5    Cano, A.6
  • 21
    • 0037086277 scopus 로고    scopus 로고
    • The SLUG zinc-finger protein represses E-cadherin in breast cancer
    • Hajra KM, Chen DY and Fearon ER. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res 2002;62:1613-1618.
    • (2002) Cancer Res , vol.62 , pp. 1613-1618
    • Hajra, K.M.1    Chen, D.Y.2    Fearon, E.R.3
  • 23
    • 34247599745 scopus 로고    scopus 로고
    • Molecular detection of SS18-SSX fusion gene transcripts by cRNA in situ hybridization in synovial sarcoma using formalin-fixed, paraffin-embedded tumor tissue specimens
    • Kanemitsu S, Hisaoka M, Shimajiri S, Matsuyama A and Hashimoto H. Molecular detection of SS18-SSX fusion gene transcripts by cRNA in situ hybridization in synovial sarcoma using formalin-fixed, paraffin-embedded tumor tissue specimens. Diagn Mol Pathol 2007;16:9-17.
    • (2007) Diagn Mol Pathol , vol.16 , pp. 9-17
    • Kanemitsu, S.1    Hisaoka, M.2    Shimajiri, S.3    Matsuyama, A.4    Hashimoto, H.5
  • 24
    • 80051962513 scopus 로고    scopus 로고
    • Immunohistochemical study of correlation between histologic subtype and expression of epithelial-mesenchymal transition-related proteins in synovial sarcomas
    • Subramaniam MM, Navarro S and Llombart-Bosch A. Immunohistochemical study of correlation between histologic subtype and expression of epithelial-mesenchymal transition-related proteins in synovial sarcomas. Arch Pathol Lab Med 2011;135:1001-1009.
    • (2011) Arch Pathol Lab Med , vol.135 , pp. 1001-1009
    • Subramaniam, M.M.1    Navarro, S.2    Llombart-Bosch, A.3
  • 27
    • 84879358593 scopus 로고    scopus 로고
    • Dishevelled-2 silencing reduces androgen-dependent prostate tumor cell proliferation and migration and expression of Wnt-3a and matrix metalloproteinases
    • Yang Y, Jiao L, Hou J, Xu C, Wang L, Yu Y, Li Y, Yang C, Wang X and Sun Y. Dishevelled-2 silencing reduces androgen-dependent prostate tumor cell proliferation and migration and expression of Wnt-3a and matrix metalloproteinases. Mol Biol Rep 2013;40:4241-50.
    • (2013) Mol Biol Rep , vol.40 , pp. 4241-4250
    • Yang, Y.1    Jiao, L.2    Hou, J.3    Xu, C.4    Wang, L.5    Yu, Y.6    Li, Y.7    Yang, C.8    Wang, X.9    Sun, Y.10
  • 29
    • 0036120137 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 expression correlates with morphological and immunohistochemical epithelial characteristics in synovial sarcoma
    • Saito T, Oda Y, Sakamoto A, Tamiya S, Iwamoto Y and Tsuneyoshi M. Matrix metalloproteinase-2 expression correlates with morphological and immunohistochemical epithelial characteristics in synovial sarcoma. Histopathology 2002;40:279-285.
    • (2002) Histopathology , vol.40 , pp. 279-285
    • Saito, T.1    Oda, Y.2    Sakamoto, A.3    Tamiya, S.4    Iwamoto, Y.5    Tsuneyoshi, M.6
  • 34
    • 33847022953 scopus 로고    scopus 로고
    • Differentially expressed genes defined by expression profiling of sarcomas with chimeric transcription factors provide an enriched source of candidate transcriptional targets
    • Saito T, Nagai M, Tsuda M and Ladanyi M. Differentially expressed genes defined by expression profiling of sarcomas with chimeric transcription factors provide an enriched source of candidate transcriptional targets. Abstracts of LXX Cold Spring Harbor Symposium 2005;225.
    • (2005) Abstracts of LXX Cold Spring Harbor Symposium , pp. 225
    • Saito, T.1    Nagai, M.2    Tsuda, M.3    Ladanyi, M.4
  • 35
    • 33745454527 scopus 로고    scopus 로고
    • Nuclear β-catenin correlates with cyclin D1 expression in spindle and pleomorphic sarcomas but not in synovial sarcoma
    • Saito T, Oda Y, Yamamoto H, Kawaguchi K, Tanaka K, Matsuda S, Iwamoto Y and Tsuneyoshi M. Nuclear β-catenin correlates with cyclin D1 expression in spindle and pleomorphic sarcomas but not in synovial sarcoma. Hum Pathol 2006;37:689-697.
    • (2006) Hum Pathol , vol.37 , pp. 689-697
    • Saito, T.1    Oda, Y.2    Yamamoto, H.3    Kawaguchi, K.4    Tanaka, K.5    Matsuda, S.6    Iwamoto, Y.7    Tsuneyoshi, M.8
  • 37
    • 0032884884 scopus 로고    scopus 로고
    • β-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer
    • Brabletz T, Jung A, Dag S, Hlubek F and Kirchner T. β-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am J Pathol 1999;155:1033-1038.
    • (1999) Am J Pathol , vol.155 , pp. 1033-1038
    • Brabletz, T.1    Jung, A.2    Dag, S.3    Hlubek, F.4    Kirchner, T.5
  • 40
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O and McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999;398:422-426.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 42
    • 0345599013 scopus 로고    scopus 로고
    • Autoregulation of E-cadherin expression by cadherin-cadherin interactions:the roles of β-catenin signaling, slug, and MAPK
    • Conacci-Sorrell M, Simcha I, Ben-Yedidia T, Blechman J, Savagner P and Ben-Ze'ev A. Autoregulation of E-cadherin expression by cadherin-cadherin interactions:the roles of β-catenin signaling, slug, and MAPK. J Cell Biol 2003;163:847-857.
    • (2003) J Cell Biol , vol.163 , pp. 847-857
    • Conacci-Sorrell, M.1    Simcha, I.2    Ben-Yedidia, T.3    Blechman, J.4    Savagner, P.5    Ben-Ze'ev, A.6
  • 43
    • 33745543651 scopus 로고    scopus 로고
    • The synovial sarcoma translocation protein SYT-SSX2 recruits β-catenin to the nucleus and associates with it in an active complex
    • Pretto D, Barco R, Rivera J, Neel N, Gustavson MD and Eid JE. The synovial sarcoma translocation protein SYT-SSX2 recruits β-catenin to the nucleus and associates with it in an active complex. Oncogene 2006;25:3661-3669.
    • (2006) Oncogene , vol.25 , pp. 3661-3669
    • Pretto, D.1    Barco, R.2    Rivera, J.3    Neel, N.4    Gustavson, M.D.5    Eid, J.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.