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Volumn 23, Issue 6, 2013, Pages 225-232

The κ-opioid receptor gene as a predictor of response in a cocaine vaccine clinical trial

Author keywords

cocaine; gene; opioid; polymorphism; treatment; vaccine

Indexed keywords

COCAINE; COCAINE VACCINE; DNA; KAPPA OPIATE RECEPTOR; METHADONE; UNCLASSIFIED DRUG; VACCINE;

EID: 84887090767     PISSN: 09558829     EISSN: 14735873     Source Type: Journal    
DOI: 10.1097/YPG.0000000000000008     Document Type: Article
Times cited : (19)

References (50)
  • 2
    • 0031452403 scopus 로고    scopus 로고
    • Manual-guided psychosocial treatment. A new virtual requirement for pharmacotherapy trials?
    • Carroll KM (1997). Manual-guided psychosocial treatment. A new virtual requirement for pharmacotherapy trials? Arch Gen Psychiatry 54: 923-928.
    • (1997) Arch Gen Psychiatry , vol.54 , pp. 923-928
    • Carroll, K.M.1
  • 3
    • 1542336803 scopus 로고    scopus 로고
    • Efficacy of disulfiram and cognitive behavior therapy in cocainedependent outpatients: A randomized placebo-controlled trial
    • Carroll KM, Fenton LR, Ball SA, Nich C, Frankforter TL, Shi J, Rounsaville BJ (2004). Efficacy of disulfiram and cognitive behavior therapy in cocainedependent outpatients: a randomized placebo-controlled trial. Arch Gen Psychiatry 61: 264-272.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 264-272
    • Carroll, K.M.1    Fenton, L.R.2    Ball, S.A.3    Nich, C.4    Frankforter, T.L.5    Shi, J.6    Rounsaville, B.J.7
  • 4
    • 19044391142 scopus 로고    scopus 로고
    • Endogenous kappa-opioid receptor systems regulate mesoaccumbal dopamine dynamics and vulnerability to cocaine
    • Chefer VI, Czyzyk T, Bolan EA, Moron J, Pintar JE, Shippenberg TS (2005). Endogenous kappa-opioid receptor systems regulate mesoaccumbal dopamine dynamics and vulnerability to cocaine. J Neurosci 25: 5029-5037.
    • (2005) J Neurosci , vol.25 , pp. 5029-5037
    • Chefer, V.I.1    Czyzyk, T.2    Bolan, E.A.3    Moron, J.4    Pintar, J.E.5    Shippenberg, T.S.6
  • 5
    • 0000381871 scopus 로고    scopus 로고
    • Local perfusion of dynorphin A 1-17 reduces extracellular dopamine levels in the nucleus accumbens
    • Claye LH, Maisonneuve IM, Yu J, Ho A, Kreek MJ (1997). Local perfusion of dynorphin A 1-17 reduces extracellular dopamine levels in the nucleus accumbens. NIDA Res Monogr 174: 113.
    • (1997) NIDA Res Monogr , vol.174 , pp. 113
    • Claye, L.H.1    Maisonneuve, I.M.2    Yu, J.3    Ho, A.4    Kreek, M.J.5
  • 6
    • 0029929428 scopus 로고    scopus 로고
    • Priming effects with drugs and other reinforcers
    • De Wit H (1996). Priming effects with drugs and other reinforcers. Exp Clin Psychopharm 4: 5-10.
    • (1996) Exp Clin Psychopharm , vol.4 , pp. 5-10
    • De Wit, H.1
  • 7
    • 29544449443 scopus 로고    scopus 로고
    • Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 and CYP450 2C19
    • DeLeon J, Armstrong SC, Cozza KL (2006). Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 and CYP450 2C19. Psychosomatics 47: 75-85.
    • (2006) Psychosomatics , vol.47 , pp. 75-85
    • Deleon, J.1    Armstrong, S.C.2    Cozza, K.L.3
  • 9
    • 0031034889 scopus 로고    scopus 로고
    • Discriminative stimulus and subjective effects of opioids with mu and kappa activity: Data from laboratory animals and human subjects
    • Dykstra LA, Preston KL, Bigelow GE (1997). Discriminative stimulus and subjective effects of opioids with mu and kappa activity: data from laboratory animals and human subjects. Psychopharmacology (Berl) 130: 14-27.
    • (1997) Psychopharmacology (Berl) , vol.130 , pp. 14-27
    • Dykstra, L.A.1    Preston, K.L.2    Bigelow, G.E.3
  • 10
    • 44849122922 scopus 로고    scopus 로고
    • A regulatory variation in OPRK1, the gene encoding the kappa-opioid receptor, is associated with alcohol dependence
    • Edenberg HJ, Wang J, Tian H, Pochareddy S, Xuei X, Wetherill L, et al. (2008). A regulatory variation in OPRK1, the gene encoding the kappa-opioid receptor, is associated with alcohol dependence. Hum Mol Genet 17: 1783-1789.
    • (2008) Hum Mol Genet , vol.17 , pp. 1783-1789
    • Edenberg, H.J.1    Wang, J.2    Tian, H.3    Pochareddy, S.4    Xuei, X.5    Wetherill, L.6
  • 12
    • 21344469970 scopus 로고    scopus 로고
    • The genetics of addictions: Uncovering the genes
    • Goldman D, Oroszi G, Ducci F (2005). The genetics of addictions: uncovering the genes. Nat Rev Genet 6: 521-532.
    • (2005) Nat Rev Genet , vol.6 , pp. 521-532
    • Goldman, D.1    Oroszi, G.2    Ducci, F.3
  • 13
    • 46249094214 scopus 로고    scopus 로고
    • Pharmacogenetic treatments for drug addiction: Alcohol and opiates
    • Haile CN, Kosten TA, Kosten TR (2008). Pharmacogenetic treatments for drug addiction: alcohol and opiates. Am J Drug Alcohol Abuse 34: 355-381.
    • (2008) Am J Drug Alcohol Abuse , vol.34 , pp. 355-381
    • Haile, C.N.1    Kosten, T.A.2    Kosten, T.R.3
  • 14
    • 68249161346 scopus 로고    scopus 로고
    • Pharmacogenetic treatments for drug addiction: Cocaine, amphetamine and methamphetamine
    • Haile CN, Kosten TR, Kosten TA (2009). Pharmacogenetic treatments for drug addiction: cocaine, amphetamine and methamphetamine. Am J Drug Alcohol Abuse 35: 161-177.
    • (2009) Am J Drug Alcohol Abuse , vol.35 , pp. 161-177
    • Haile, C.N.1    Kosten, T.R.2    Kosten, T.A.3
  • 15
    • 71349084953 scopus 로고    scopus 로고
    • Cocainespecific antibodies blunt the subjective effects of smoked cocaine in humans
    • Haney M, Gunderson EW, Jiang H, Collins ED, Foltin RW (2010). Cocainespecific antibodies blunt the subjective effects of smoked cocaine in humans. Biol Psychiatry 67: 59-65.
    • (2010) Biol Psychiatry , vol.67 , pp. 59-65
    • Haney, M.1    Gunderson, E.W.2    Jiang, H.3    Collins, E.D.4    Foltin, R.W.5
  • 16
    • 0028071283 scopus 로고
    • U-69593 prevents cocaine sensitization by normalizing basal accumbens dopamine
    • Heidbreder CA, Shippenberg TS (1994). U-69593 prevents cocaine sensitization by normalizing basal accumbens dopamine. Neuroreport 5: 1797-1800.
    • (1994) Neuroreport , vol.5 , pp. 1797-1800
    • Heidbreder, C.A.1    Shippenberg, T.S.2
  • 19
    • 0032589934 scopus 로고    scopus 로고
    • Dynorphin A1-13 causes elevation of serum levels of prolactin through an opioid receptor mechanism in humans: Gender differences and implications for modulation of dopaminergic tone in the treatment of addictions
    • Kreek MJ, Schluger J, Borg L, Gunduz M, Ho A (1999). Dynorphin A1-13 causes elevation of serum levels of prolactin through an opioid receptor mechanism in humans: gender differences and implications for modulation of dopaminergic tone in the treatment of addictions. J Pharmacol Exp Ther 288: 260-269.
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 260-269
    • Kreek, M.J.1    Schluger, J.2    Borg, L.3    Gunduz, M.4    Ho, A.5
  • 20
    • 84855339940 scopus 로고    scopus 로고
    • Epistatic effects between variants of kappa-opioid receptor gene and A118G of mu-opioid receptor gene increase susceptibility to addiction in Indian population
    • Kumar D, Chakraborty J, Das S (2012). Epistatic effects between variants of kappa-opioid receptor gene and A118G of mu-opioid receptor gene increase susceptibility to addiction in Indian population. Prog Neuropsychopharmacol Biol Psychiatry 36: 225-230.
    • (2012) Prog Neuropsychopharmacol Biol Psychiatry , vol.36 , pp. 225-230
    • Kumar, D.1    Chakraborty, J.2    Das, S.3
  • 21
    • 35848962100 scopus 로고    scopus 로고
    • The pharmacogenetics of major depression: Past, present, and future
    • Laje G, McMahon FJ (2007). The pharmacogenetics of major depression: past, present, and future. Biol Psychiatry 62: 1205-1207.
    • (2007) Biol Psychiatry , vol.62 , pp. 1205-1207
    • Laje, G.1    McMahon, F.J.2
  • 22
    • 0030816449 scopus 로고    scopus 로고
    • Addiction is a brain disease, and it matters
    • Leshner AI (1997). Addiction is a brain disease, and it matters. Science 278: 45-47.
    • (1997) Science , vol.278 , pp. 45-47
    • Leshner, A.I.1
  • 26
    • 70349690285 scopus 로고    scopus 로고
    • Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: A randomized, double-blind, placebo-controlled efficacy trial
    • Martell BA, Orson FM, Poling J, Mitchell E, Rossen RD, Gardner T, Kosten TR (2009). Cocaine vaccine for the treatment of cocaine dependence in methadone-maintained patients: a randomized, double-blind, placebo-controlled efficacy trial. Arch Gen Psychiatry 66: 1116-1123.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 1116-1123
    • Martell, B.A.1    Orson, F.M.2    Poling, J.3    Mitchell, E.4    Rossen, R.D.5    Gardner, T.6    Kosten, T.R.7
  • 27
    • 0038383854 scopus 로고    scopus 로고
    • Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses
    • McLaughlin JP, Marton-Popovici M, Chavkin C (2003). Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses. J Neurosci 23: 5674-5683.
    • (2003) J Neurosci , vol.23 , pp. 5674-5683
    • McLaughlin, J.P.1    Marton-Popovici, M.2    Chavkin, C.3
  • 29
    • 0034605531 scopus 로고    scopus 로고
    • Drug dependence, a chronic medical illness: Implications for treatment, insurance, and outcomes evaluation
    • McLellan AT, Lewis DC, O'Brien CP, Kleber HD (2000). Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation. JAMA 284: 1689-1695.
    • (2000) JAMA , vol.284 , pp. 1689-1695
    • McLellan, A.T.1    Lewis, D.C.2    O'brien, C.P.3    Kleber, H.D.4
  • 31
    • 84887084031 scopus 로고    scopus 로고
    • R: A language and environment for statistical computing 2. 9. 1. Vienna, Austria
    • R Development Core Team
    • R Development Core Team (2009). R: a language and environment for statistical computing 2.9.1. Vienna, Austria: R Foundation for Statistical Computing.
    • (2009) R Foundation for Statistical Computing
  • 32
    • 0037115525 scopus 로고    scopus 로고
    • Pharmacogenetics affects dosing, efficacy, and toxicity of cytochrome P450-metabolized drugs
    • Rogers JF, Nafziger AN, Bertino JSJ (2002). Pharmacogenetics affects dosing, efficacy, and toxicity of cytochrome P450-metabolized drugs. Am J Med 113: 746-750.
    • (2002) Am J Med , vol.113 , pp. 746-750
    • Rogers, J.F.1    Nafziger, A.N.2    Jsj, B.3
  • 34
    • 84887064779 scopus 로고    scopus 로고
    • Rockville, MD: Substance Abuse and Mental Health Services Administration
    • Rockville, MD: Substance Abuse and Mental Health Services Administration.
  • 36
    • 0032481350 scopus 로고    scopus 로고
    • Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50, 488H and attenuates morphine withdrawal
    • Simonin F, Valverde O, Smadja C, Slowe S, Kitchen I, Dierich A, et al. (1998). Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50,488H and attenuates morphine withdrawal. EMBO J 17: 886-897.
    • (1998) EMBO J. , vol.17 , pp. 886-897
    • Simonin, F.1    Valverde, O.2    Smadja, C.3    Slowe, S.4    Kitchen, I.5    Dierich, A.6
  • 37
    • 0036272535 scopus 로고    scopus 로고
    • A national 5-year follow-up of treatment outcomes for cocaine dependence
    • Simpson DD, Joe GW, Broome KM (2002). A national 5-year follow-up of treatment outcomes for cocaine dependence. Arch Gen Psychiatry 59: 538-565.
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 538-565
    • Simpson, D.D.1    Joe, G.W.2    Broome, K.M.3
  • 38
    • 33645120326 scopus 로고    scopus 로고
    • Emerging pharmacological strategies in the fight against cocaine addiction
    • Sofuoglu M, Kosten TR (2006). Emerging pharmacological strategies in the fight against cocaine addiction. Expert Opin Investig Drugs 11: 91-98.
    • (2006) Expert Opin Investig Drugs , vol.11 , pp. 91-98
    • Sofuoglu, M.1    Kosten, T.R.2
  • 39
    • 0025107375 scopus 로고
    • The effects of opioid peptides on dopamine release in the nucleus accumbens: An in vivo microdialysis study
    • Spanagel R, Herz A, Shippenberg TS (1990). The effects of opioid peptides on dopamine release in the nucleus accumbens: an in vivo microdialysis study. J Neurochem 55: 1734-1740.
    • (1990) J Neurochem , vol.55 , pp. 1734-1740
    • Spanagel, R.1    Herz, A.2    Shippenberg, T.S.3
  • 40
    • 85047700129 scopus 로고    scopus 로고
    • Cocaine, reward, movement and monoamine transporters
    • Uhl GR, Hall FS, Sora I (2002). Cocaine, reward, movement and monoamine transporters. Mol Psychiatry 7: 21-26.
    • (2002) Mol Psychiatry , vol.7 , pp. 21-26
    • Uhl, G.R.1    Hall, F.S.2    Sora, I.3
  • 41
    • 0028110978 scopus 로고
    • Repeated cocaine administration upregulates kappa and mu, but not delta, opioid receptors
    • Unterwald EM, Rubenfeld JM, Kreek MJ (1994). Repeated cocaine administration upregulates kappa and mu, but not delta, opioid receptors. Neuroreport 5: 1613-1616.
    • (1994) Neuroreport , vol.5 , pp. 1613-1616
    • Unterwald, E.M.1    Rubenfeld, J.M.2    Kreek, M.J.3
  • 42
    • 0035805085 scopus 로고    scopus 로고
    • The frequency of cocaine administration impacts cocaine-induced receptor alterations
    • Unterwald EM, Kreek MJ, Cuntapay M (2001). The frequency of cocaine administration impacts cocaine-induced receptor alterations. Brain Res 900: 103-109.
    • (2001) Brain Res , vol.900 , pp. 103-109
    • Unterwald, E.M.1    Kreek, M.J.2    Cuntapay, M.3
  • 43
    • 0034807831 scopus 로고    scopus 로고
    • Enadoline and butorphanol: Evaluation of kappa-agonists on cocaine pharmacodynamics and cocaine self-administration in humans
    • Walsh SL, Geter-Douglas B, Strain EC, Bigelow GE (2001a). Enadoline and butorphanol: evaluation of kappa-agonists on cocaine pharmacodynamics and cocaine self-administration in humans. J Pharmacol Exp Ther 299: 147-158.
    • (2001) J Pharmacol Exp Ther , vol.299 , pp. 147-158
    • Walsh, S.L.1    Geter-Douglas, B.2    Strain, E.C.3    Bigelow, G.E.4
  • 44
    • 0034873586 scopus 로고    scopus 로고
    • Enadoline, a selective kappa opioid agonist: Comparison with butorphanol and hydromorphone in humans
    • Walsh SL, Strain EC, Abreu ME, Bigelow GE (2001b). Enadoline, a selective kappa opioid agonist: comparison with butorphanol and hydromorphone in humans. Psychopharmacology (Berl) 157: 151-162.
    • (2001) Psychopharmacology (Berl) , vol.157 , pp. 151-162
    • Walsh, S.L.1    Strain, E.C.2    Abreu, M.E.3    Bigelow, G.E.4
  • 45
    • 0038391177 scopus 로고    scopus 로고
    • How important is treatment?Oneyear outcomes of treated and untreated alcohol-dependent individuals
    • Weisner C, Matzger H, Kaskutas LA (2003). How important is treatment? Oneyear outcomes of treated and untreated alcohol-dependent individuals. Addiction 98: 901-911.
    • (2003) Addiction , vol.98 , pp. 901-911
    • Weisner, C.1    Matzger, H.2    Kaskutas, L.A.3
  • 47
    • 11144235902 scopus 로고    scopus 로고
    • Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction
    • Yuferov V, Fussell D, LaForge KS, Nielsen DA, Gordon D, Ho A, et al. (2004). Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction. Pharmacogenetics 14: 793-804.
    • (2004) Pharmacogenetics , vol.14 , pp. 793-804
    • Yuferov, V.1    Fussell, D.2    Laforge, K.S.3    Nielsen, D.A.4    Gordon, D.5    Ho, A.6
  • 48
    • 42349085474 scopus 로고    scopus 로고
    • The OPRD1 and OPRK1 loci in alcohol or drug dependence: OPRD1 variation modulates substance dependence risk
    • Zhang H, Kranzler HR, Yang BZ, Luo X, Gelernter J (2008). The OPRD1 and OPRK1 loci in alcohol or drug dependence: OPRD1 variation modulates substance dependence risk. Mol Psychiatry 13: 531-543.
    • (2008) Mol Psychiatry , vol.13 , pp. 531-543
    • Zhang, H.1    Kranzler, H.R.2    Yang, B.Z.3    Luo, X.4    Gelernter, J.5
  • 49
    • 2442488532 scopus 로고    scopus 로고
    • Effect of the endogenous kappa opioid agonist dynorphin A(1-17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice
    • Zhang Y, Butelman ER, Schlussman SD, Ho A, Kreek MJ (2004a). Effect of the endogenous kappa opioid agonist dynorphin A(1-17) on cocaine-evoked increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice. Psychopharmacology (Berl) 172: 422-429.
    • (2004) Psychopharmacology (Berl) , vol.172 , pp. 422-429
    • Zhang, Y.1    Butelman, E.R.2    Schlussman, S.D.3    Ho, A.4    Kreek, M.J.5
  • 50
    • 2342545387 scopus 로고    scopus 로고
    • Effect of the kappa opioid agonist R-84760 on cocaine-induced increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice
    • Zhang Y, Butelman ER, Schlussman SD, Ho A, Kreek MJ (2004b). Effect of the kappa opioid agonist R-84760 on cocaine-induced increases in striatal dopamine levels and cocaine-induced place preference in C57BL/6J mice. Psychopharmacology (Berl) 173: 146-152.
    • (2004) Psychopharmacology (Berl) , vol.173 , pp. 146-152
    • Zhang, Y.1    Butelman, E.R.2    Schlussman, S.D.3    Ho, A.4    Kreek, M.J.5


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