A Choice-based screening method for compulsive drug users in rats

Current Protocols in Neuroscience

Volumn 1, Issue SUPPL.64, 2013, Pages

  Lenoir, Magalie ^a   Augier, Eric ^a   Vouillac, Caroline ^a   Ahmed, Serge H ^a  

^a UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Addiction; Animal model; Choice; Cocaine; Saccharin; Screening

Indexed keywords

COCAINE; SACCHARIN; DOPAMINE UPTAKE INHIBITOR; SWEETENING AGENT;

ADULT; ANIMAL EXPERIMENT; ARTICLE; CHOICE BASED SCREENING; CLINICAL PROTOCOL; COMPULSION; CONTROLLED STUDY; DRUG INTOXICATION; DRUG SELF ADMINISTRATION; DRUG USE; EXPERIMENTAL REWARD ADDICTION TEST; MALE; NONHUMAN; OPERANT BEHAVIORAL TEST; PRIORITY JOURNAL; RAT; REINFORCEMENT; SCREENING; YOUNG ADULT; ANIMAL; COMPULSIVE BEHAVIOR; DECISION MAKING; DISEASE MODEL; DRUG ADMINISTRATION ROUTE; DRUG SEEKING BEHAVIOR; INSTRUMENTAL CONDITIONING; PATHOPHYSIOLOGY; PHYSIOLOGY; REWARD; SUBSTANCE ABUSE; TIME; WISTAR RAT;

ANIMALS; CHOICE BEHAVIOR; COCAINE; COMPULSIVE BEHAVIOR; CONDITIONING, OPERANT; DISEASE MODELS, ANIMAL; DOPAMINE UPTAKE INHIBITORS; DRUG ADMINISTRATION ROUTES; DRUG-SEEKING BEHAVIOR; RATS; RATS, WISTAR; REWARD; SACCHARIN; SELF ADMINISTRATION; SUBSTANCE ABUSE DETECTION; SWEETENING AGENTS; TIME FACTORS;

EID: 84887086671     PISSN: 19348584     EISSN: 19348576     Source Type: Journal    
DOI: 10.1002/0471142301.ns0944s64     Document Type: Article

References (36)

1. Ahmed, S.H. 2010. Validation crisis in animal models of drug addiction: Beyond non-disordered drug use toward drug addiction. Neurosci. Biobehav. Rev. 35:172-184.
2. Ahmed, S.H. 2012. The science of making drugaddicted animals. Neuroscience 211:107-125.
3. Ahmed, S.H. and Koob, G.F. 1998. Transition from moderate to excessive drug intake: Change in hedonic set point. Science 282:298-300.
4. Ahmed, S.H., Kenny, P.J., Koob, G.F., and Markou, A. 2002. Neurobiological evidence for hedonic allostasis associated with escalating cocaine use. Nat. Neurosci. 5:625-626.
5. Aigner, T.G. and Balster, R.L. 1978. Choice behavior in rhesus monkeys: Cocaine versus food. Science 201:534-535.
6. American Psychiatric Association. 2000. Diagnostic and Statistical Manual of Mental Disorders, revised 4th ed. American Psychiatric Association Washington, D.C.
7. Anthony, J.C. 2002. Epidemiology of drug dependence. In Neuropsychopharmacology: The Fifth Generation of Progress (K.L. Davis,D. Charney,J.T. Coyle, andC. Nemeroff, eds.) pp. 1557-1573. Lippincott Williams and Wilkins, Philadelphia.
8. Anthony, J.C., Warner, L.A., and Kessler, R.C. 1994. Comparative epidemiology of dependence on tobacco, alcohol, controlled substances, and inhalants: Basic findings from the National Comorbidity Survey. Exp. Clin. Psychopharmacol. 2:224-268.
9. Augier, E., Vouillac, C., and Ahmed, S.H. 2012. Diazepam promotes choice of abstinence in cocaine self-administering rats. Addict. Biol. 17:378-391.
10. Belin, D. and Deroche-Gamonet, V. 2012. Responses to novelty and vulnerability to cocaine addiction: Contribution of a multi-symptomatic animal model. Cold SpringHarb.Perspect.Med. doi:10.1101/cshperspect.a011940.
11. Cantin, L., Lenoir, M., Augier, E., Vanhille, N., Dubreucq, S., Serre, F., Vouillac, C., and Ahmed, S.H. 2010. Cocaine is low on the value ladder of rats: Possible evidence for resilience to addiction. PLoS One 5:e11592.
12. Collier, G. and Novell, K. 1967. Saccharin as a sugar surrogate. J. Comp. Physiol. Psychol. 64: 401-408.
13. Degenhardt, L., Bohnert, K.M., and Anthony, J.C. 2008. Assessment of cocaine and other drug dependence in the general population: "Gated" versus "ungated" approaches. Drug Alcohol Depend. 93:227-232.
14. Deroche-Gamonet, V., Belin, D., and Piazza, P.V. 2004. Evidence for addiction-like behavior in the rat. Science 305:1014-1017.
15. Haney, M. 2009. Self-administration of cocaine, cannabis and heroin in the human laboratory: Benefits and pitfalls. Addict. Biol. 14:9-21.
16. Heilig, M., Thorsell, A., Sommer, W.H., Hansson, A.C., Ramchandani, V.A., George, D.T., Hommer, D., and Barr, C.S. 2010. Translating the neuroscience of alcoholism into clinical treatments: From blocking the buzz to curing the blues. Neurosci. Biobehav. Rev. 35:334-344.
17. Hyman, S.E. 2007. Can neuroscience be integrated into the DSM-V? Nat. Rev. Neurosci. 8:725-732.
18. Hyman, S.E. and Malenka, R.C. 2001. Addiction and the brain: The neurobiology of compulsion and its persistence. Nat. Rev. Neurosci. 2:695-703.
19. Kerstetter, K.A., Ballis, M.A., Duffin-Lutgen, S., Carr, A.E., Behrens, A.M., and Kippin, T.E. 2012. Sex differences in selecting between food and cocaine reinforcement are mediated by estrogen. Neuropsychopharmacology 37:2605-614.
20. Koob, G.F., Kenneth Lloyd, G., and Mason, B.J. 2009. Development of pharmacotherapies for drug addiction: A Rosetta stone approach. Nat. Rev. Drug Discov. 8:500-515.
21. Lenoir, M., Serre, F., Cantin, L., and Ahmed, S.H. 2007. Intense sweetness surpasses cocaine reward. PLoS One 2:e698.
22. Lenoir, M., Cantin, L., Vanhille, N., Serre, F., and Ahmed, S.H. 2013. Extended heroin access increases heroin choices over a potent nondrug alternative. Neuropsychopharmacology 38:1209-1220.
23. Martin, C.S., Chung, T., and Langenbucher, J.W. 2008. How should we revise diagnostic criteria for substance use disorders in the DSM-V? J. Abnorm. Psychol. 117:561-575.
24. Nader,M.A. andWoolverton,W.L. 1991. Effects of increasing the magnitude of an alternative reinforcer on drug choice in a discrete-trials choice procedure. Psychopharmacology 105:169-174.
25. Nutt, D., King, L.A., Saulsbury, W., and Blakemore, C. 2007. Development of a rational scale to assess the harm of drugs of potential misuse. Lancet 369:1047-1053.
26. O'Connor,E.C., Chapman, K.,Butler, P., and Mead, A.N. 2010. The predictive validity of the rat selfadministration model for abuse liability. Neurosci. Biobehav. Rev. 35:912-938.
27. Pickens, R. and Thompson, T. 1968. Cocainereinforced behavior in rats: Effects of reinforcement magnitude and fixed-ratio size. J. Pharmacol. Exp. Ther. 161:122-129.
28. Smith, J.C. and Sclafani, A. 2002. Saccharin as a sugar surrogate revisited. Appetite 38:155-160.
29. Solinas, M., Panlilio, L.V., Justinova, Z., Yasar, S., and Goldberg, S.R. 2006. Using drugdiscrimination techniques to study the abuserelated effects of psychoactive drugs in rats. Nat. Protoc. 1:1194-1206.
30. Spragg, S.D.S. 1940. Morphine addiction in chimpanzees. Comp. Psychol. Monogr. 15:1-132.
31. Stein, D.J., Phillips, K.A., Bolton, D., Fulford, K.W., Sadler, J.Z., and Kendler, K.S. 2010. What is a mental/psychiatric disorder. From DSM-IV to DSM-V. Psychol. Med. 40:1759-1765.
32. Thompson, T. and Schuster, C.R. 1964. Morphine self-administration, food-reinforced, and avoidance behaviors in rhesus monkeys. Psychopharmacologia 5:87-94.
33. Vosburg, S. K., Haney, M., Rubin, E., and Foltin, R.W. 2010. Using a novel alternative to drug choice in a human laboratory model of a cocaine binge:Agame of chance. Drug Alcohol Depend. 110:144-150.
34. Wakefield, J.C. 2007. The concept of mental disorder: Diagnostic implications of the harmful dysfunction analysis. World Psychiatry 6:149-156.
35. Walsh, S.L., Donny, E.C., Nuzzo, P.A., Umbricht, A., and Bigelow, G.E. 2010. Cocaine abuse versus cocaine dependence: Cocaine selfadministration and pharmacodynamic response in the human laboratory. Drug Alcohol Depend. 106:28-37.
36. Weeks, J.R. 1962. Experimental morphine addiction: method for automatic intravenous injections in unrestrained rats. Science 138:143-144.