Size and CT density of iodine-containing ethosomal vesicles obtained by membrane extrusion: Potential for use as CT contrast agents

Biotechnology Journal

Volumn 8, Issue 11, 2013, Pages 1347-1353

  Na, Bomin ^a   Choi, Byoung Wook ^b   Kim, Bumsang ^a  

^a Hong Ik University   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

Computed tomography (CT); Contrast agents; Ethosomes; Extrusion; Macrophages

Indexed keywords

CELLULAR TOXICITIES; CONTRAST AGENT; ETHOSOMES; EXTRUSION TECHNIQUES; IODINE CONCENTRATION; MEMBRANE EXTRUSIONS; NON-INVASIVE IMAGING; POLYCARBONATE MEMBRANES;

EXTRUSION; IMAGING TECHNIQUES; IODINE; LIPID BILAYERS; MACROPHAGES;

COMPUTERIZED TOMOGRAPHY;

IODINATED CONTRAST MEDIUM; POLYCARBONATE;

ARTICLE; CELL DENSITY; CELL ENCAPSULATION; CELL SIZE; CELL STRUCTURE; CELL VACUOLE; CELL VIABILITY; CONCENTRATION (PARAMETERS); DISPERSION; DRUG CYTOTOXICITY; IN VIVO STUDY; KUPFFER CELL; LIPID BILAYER; MACROPHAGE; PARTICLE SIZE; PHAGOCYTOSIS; PRIORITY JOURNAL; SPIRAL COMPUTER ASSISTED TOMOGRAPHY;

COMPUTED TOMOGRAPHY (CT); CONTRAST AGENTS; ETHOSOMES; EXTRUSION; MACROPHAGES;

ANIMALS; CELL LINE; CONTRAST MEDIA; HUMANS; IODINE; LIVER; MACROPHAGES; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; TOMOGRAPHY, X-RAY COMPUTED; TRANSPORT VESICLES;

EID: 84887082551     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201300110     Document Type: Article

References (26)

1. Dai, X., Schlemmer, H.-P., Schmidt, B., Hoh, K. et al., Quantitative therapy response assessment by volumetric iodine-uptake measurement: Initial experience in patients with advanced hepatocellular carcinoma treated with sorafenib. Eur. J. Radiol. 2013, 82, 327-334.
2. Montet, X., Pastor, C. M., Vallee, J.-P., Becker, C. D. et al., Improved visualization of vessels and hepatic tumors by micro-computed tomography (CT) using iodinated liposomes. Invest. Radiol. 2007, 42, 652-658.
3. Leander, P., Hoglund, P., Borseth, A., Kloster, Y., Berg, A., A new liposomal liver-specific contrast agent for CT: First human phase-I clinical trial assessing efficacy and safety. Eur. Radiol. 2001, 11, 698-704.
4. Kemmerer, S. R., Mortele, K. J., Ros, P. R., CT scan of the liver. Radiol. Clin. North Am. 1998, 36, 247-260.
5. Baron, R. L., Understanding and optimizing use of contrast material for CT of the liver. Am. J. Roentgenol. 1994, 163, 323-331.
6. Zheng, J., Liu, J., Dunne, M., Jaffray, D. A., Allen, C., In vivo performance of a liposomal vascular contrast agent for CT and MR-based image guidance applications. Pharm. Res. 2007, 24, 1193-120.
7. Katayama, H., Spinazzi, A., Fouillet, X., Kirchin, M. A. et al., Iomeprol: Current and future profile of a radiocontrast agent. Invest. Radiol. 2001, 36, 87-96.
8. Celia, C., Cilurzo, F., Trapasso, E., Cosco, D. et al., Ethosomes® and transfersomes® containing linoleic acid: Physicochemical and technological features of topical drug delivery carriers for the potential treatment of melasma disorders. Biomed. Microdevices 2012, 14, 119-130.
9. Xing, X. J., Yang, L., You, Y., Zhong, B. Y. et al., Study of the biological function and penetration pathways of the mouse epidermal growth factor ethosomal delivery system. Exp. Dermatol. 2011, 20, 945-947.
10. Ainbinder, D., Paolino, D., Fresta, M., Touitou, E., Drug delivery applications with ethosomes. J. Biomed. Nanotechnol. 2010, 6, 558-568.
11. Paolino, D., Lucania, G., Mardente, D., Alhaique, F., Fresta, M., Ethosomes for skin delivery of ammonium glycyrrhizinate: In vitro percutaneous permeation through human skin and in vivo anti-inflammatory activity on human volunteers. J. Control. Rel. 2005, 106, 99-110.
12. Touitou, E., Dayan, N., Bergelson, L., Godin, B., Eliaz, M., Ethosomes - novel vesicular carriers for enhanced delivery: Characterization and skin penetration properties. J. Control. Rel. 2000, 65, 403-418.
13. Gaillard, P. J., Appeldoorn, C. C. M., Rip, J., Dorland, R. et al., Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation. J. Control. Rel. 2012, 164, 364-369.
14. Leung, S. J., Romanowski, M., Molecular Catch and Release: Controlled delivery using optical trapping with light-responsive liposomes. Adv. Mater. 2012, 24, 6380-6383.
15. Al-Jamal, W. T., Kostarelos, K., Liposomes: From a clinically established drug delivery system to a nanoparticle platform for theranostic nanomedicine. Accounts Chem. Res. 2011, 44, 1094-1104.
16. Longmuir, K. J., Haynes, S. M., Baratta, J. L., Kasabwalla, N., Robertson, R. T., Liposomal delivery of doxorubicin to hepatocytes in vivo by targeting heparin sulfate. Int. J. Pharmaceut. 2009, 382, 222-233.
17. Biruss, B., Valenta, C., Skin permeation of different hormones from polymeric coated liposomal formulations. Eur. J. Pharm. Biopharm. 2006, 62, 210-219.
18. Cortesi, R., Romagnoli, R., Drechsler, M., Menegatti, E. et al., Liposomes- and ethosomes-associated distamycins: A comparative study. J. Liposome Res. 2010, 20, 277-285.
19. Dayan, N., Touitou, E., Carriers for skin delivery of trihexyphenidyl HCl: Ethosomes vs. liposomes. Biomaterials 2000, 21, 1879-1885.
20. Elrod, D. B., Partha, R., Danila, D., Casscells, S. W., Conyers, J. L., An iodinated liposomal computed tomographic contrast agent prepared from a diiodophosphatidylcholine lipid. Nanomed.-Nanotechnol. 2009, 5, 42-45.
21. Kao, C.-Y., Hoffman, E. A., Beck, K. C., Bellamkonda, R. V., Annapragada, A. V., Long-residence-time nano-scale liposomal iohexol for X-ray-based blood pool imaging. Acad. Radiol. 2003, 10, 475-48.
22. Desser, T. S., Rubin, D. L., Muller, H., Mclntire, G. L. et al., Blood pool and liver enhancement in CT with liposomal iodixanol: Comparison with iohexol. Acad. Radiol. 1999, 6, 176-183.
23. Hyafil, F., Cornily, J.-C., Feig, J. E., Gordon, R. et al., Noninvasive detection of macrophages using a nanoparticulate contrast agent for computed tomography. Nat. Med. 2007, 13, 636-641.
24. Campli, C. D., Wu, J., Zern, M. A., Targeting of therapeutics to the liver: Liposomes and viral vectors. Alcohol. Clin. Exp. Res. 1999, 23, 950-954.
25. Olson, F., Hunt, C. A., Szoka, F. C., Vail, W. J., Papahadjopoulos, D., Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes. Biochim. Biophys. Acta 1979, 557, 9-23.
26. Hope, M. J., Bally, M. B., Webb, G., Cullis, P. R., Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential. Biochim. Biophys. Acta 1985, 812, 55-65.