Quantitative therapy response assessment by volumetric iodine-uptake measurement: Initial experience in patients with advanced hepatocellular carcinoma treated with sorafenib

European Journal of Radiology

Volumn 82, Issue 2, 2013, Pages 327-334

  Dai, Xu ^a,b   Schlemmer, Heinz Peter ^b   Schmidt, Bernhard ^c   Höh, Karolin ^d   Xu, Ke ^a   Ganten, Tom M ^d   Ganten, Maria Katharina ^b  

^a CHINA MEDICAL UNIVERSITY   (China)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c SIEMENS AG   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

CT density; DECT; Hepatocellular carcinoma; Response evaluation; Sorafenib; Volumetric iodine uptake

Indexed keywords

IODINE; IOMEPROL; IOMEPROL 400; SORAFENIB; UNCLASSIFIED DRUG;

ADULT; ADVANCED CANCER; AGED; AMERICAN ASSOCIATION FOR THE STUDY OF LIVER DISEASE; ARTICLE; CANCER CHEMOTHERAPY; CANCER CONTROL; CANCER PATIENT; CHOI CRITERIA; CLINICAL ARTICLE; CLINICAL ASSESSMENT TOOL; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DUAL ENERGY COMPUTER TOMOGRAPHY; FEMALE; FOLLOW UP; HUMAN; INTERMETHOD COMPARISON; LIVER CELL CARCINOMA; MALE; OUTCOME ASSESSMENT; PATIENT MONITORING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIOLOGICAL PARAMETERS; RETROSPECTIVE STUDY; SCORING SYSTEM; TREATMENT RESPONSE; VOLUMETRIC IODINE UPTAKE;

AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CONTRAST MEDIA; FEMALE; HUMANS; IMAGING, THREE-DIMENSIONAL; IOPAMIDOL; LIVER NEOPLASMS; MALE; MIDDLE AGED; NIACINAMIDE; OUTCOME ASSESSMENT (HEALTH CARE); PHENYLUREA COMPOUNDS; PILOT PROJECTS; RADIOGRAPHY, DUAL-ENERGY SCANNED PROJECTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 84871921194     PISSN: 0720048X     EISSN: 18727727     Source Type: Journal    
DOI: 10.1016/j.ejrad.2012.11.013     Document Type: Article

References (20)

1. H.B. El-Serag, and K.L. Rudolph Hepatocellular carcinoma: epidemiology and molecular carcinogenesis Gastroenterology 132 7 2007 2557 2576
2. J.M. Llovet, S. Ricci, and V. Mazzaferro Sorafenib in advanced hepatocellular carcinoma New England Journal of Medicine 359 4 2008 378 390
3. S.M. Wilhelm, L. Adnane, P. Newell, A. Villanueva, J.M. Llovet, and M. Lynch Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling Molecular Cancer Therapeutics 7 10 2008 3129 3140
4. M. Horger, U.M. Lauer, and C. Schraml Early MRI response monitoring of patients with advanced hepatocellular carcinoma under treatment with the multikinase inhibitor sorafenib BMC Cancer 9 2009 208 218
5. E.A. Eisenhauer, P. Therasse, and J. Bogaerts New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1) European Journal of Cancer 45 2 2009 228 247
6. T. Jiang, A. Kambadakone, N.M. Kulkarni, A.X. Zhu, and D.V. Sahani Monitoring response to antiangiogenic treatment and predicting outcomes in advanced hepatocellular carcinoma using image biomarkers, CT perfusion, tumor density, and tumor size (RECIST) Investigative Radiology 47 1 2012 11 17
7. S.C. Efremidis, P. Hytiroglou, and O. Matsui Enhancement patterns and signal-intensity characteristics of small hepatocellular carcinoma in cirrhosis: pathologic basis and diagnostic challenges European Radiology 17 11 2007 2969 2982
8. J. Bruix, M. Sherman, and J.M. Llovet Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver Journal of Hepatology 35 3 2001 421 430
9. R. Lencioni, and J.M. Llovet Modified RECIST (mRECIST) assessment for hepatocellular carcinoma Seminars in Liver Disease 30 1 2010 52 60
10. J. Bruix, and M. Sherman American Association for the Study of Liver Diseases. Management of hepatocellular carcinoma: an update Hepatology 53 3 2011 1020 1022
11. D. Spira, M. Fenchel, and U.M. Lauer Comparison of different tumor response criteria in patients with hepatocellular carcinoma after systemic therapy with the multikinase inhibitor sorafenib Academic Radiology 18 1 2011 89 96
12. C.S. van Kessel, M.S. van Leeuwen, P.O. Witteveen, T.C. Kwee, H.M. Verkooijen, and R. van Hillegersberg Semi-automatic software increases CT measurement accuracy but not response classification of colorectal liver metastases after chemotherapy European Journal of Radiology January 2012 10.1016/j.ejrad.2011.12.026
13. H. Choi, C. Charnsangavej, and S.C. Faria Correlation of computed tomography and positron emission tomography in patients with metastatic gastrointestinal stromal tumor treated at a single institution with imatinib mesylate: proposal of new computed tomography response criteria Journal of Clinical Oncology 25 13 2007 1753 1759
14. S. Faivre, M. Zappa, and V. Vilgrain Changes in tumor density in patients with advanced hepatocellular carcinoma treated with sunitinib Clinical Cancer Research 17 13 2011 4504 4512
15. F. Rombolà, A. Caravetta, F. Mollo, A. Spinoso, L. Peluso, and R. Guarino Sorafenib, risk of bleeding and spontaneous rupture of hepatocellular carcinoma. A clinical case Acta Medica (Hradec Kralove) 54 4 2011 177 179
16. P. Apfaltrer, M. Meyer, and C. Meier Contrast-enhanced dual-energy CT of gastrointestinal stromal tumors: is iodine-related attenuation a potential indicator of tumor response? Investigative Radiology 47 1 2012 65 70
17. T.R. Johnson, B. Krauss, and M. Sedlmair Material differentiation by dual energy CT: initial experience European Radiology 17 6 2007 1510 1517
18. J.M. Llovet, A.M. Di Bisceglie, and J. Bruix Design and endpoints of clinical trials in hepatocellular carcinoma Journal of the National Cancer Institute 100 10 2008 698 711
19. 18F]-fluorodeoxyglucose and positron emission tomography: review and 1999 EORTC recommendations. European Organization for Research and Treatment of Cancer (EORTC) PET Study Group European Journal of Cancer 35 13 1999 1773 1782
20. S. Mangold, C. Thomas, and M. Fenchel Virtual nonenhanced dual-energy CT urography with tin-filter technology: determinants of detection of urinary calculi in the renal collecting system Radiology 264 1 2012 119 125