Liposomal bupivacaine as a single-injection peripheral nerve block: A dose-response study

Anesthesia and Analgesia

Volumn 117, Issue 5, 2013, Pages 1248-1256

  Ilfeld, Brian M ^a   Malhotra, Nisha ^a   Furnish, Timothy J ^a   Donohue, Michael C ^a   Madison, Sarah J ^a  

^a University of California   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUPIVACAINE; DIAZEPAM; DELAYED RELEASE FORMULATION; DRUG CARRIER; LIPOSOME; LOCAL ANESTHETIC AGENT;

ADULT; ARTICLE; CHILL; DOSE RESPONSE; ELECTRIC CURRENT; ERYTHEMA; EXUDATE; FEMALE; FEMORAL NERVE; FEVER; FOOD AND DRUG ADMINISTRATION; HUMAN; INJECTION SITE PRURITUS; MALE; MUSCLE ISOMETRIC CONTRACTION; NAUSEA AND VOMITING; NERVE BLOCK; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; RASH; RIGOR; ADMINISTRATION AND DOSAGE; CHEMISTRY; COHORT ANALYSIS; CONTROLLED STUDY; DELAYED RELEASE FORMULATION; DRUG EFFECTS; PERIPHERAL NERVOUS SYSTEM; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; TIME; TREATMENT OUTCOME;

ADULT; ANESTHETICS, LOCAL; BUPIVACAINE; COHORT STUDIES; DELAYED-ACTION PREPARATIONS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; FEMALE; HUMANS; LIPOSOMES; MALE; NERVE BLOCK; PERIPHERAL NERVOUS SYSTEM; TIME FACTORS; TREATMENT OUTCOME;

EID: 84887056859     PISSN: 00032999     EISSN: 15267598     Source Type: Journal    
DOI: 10.1213/ANE.0b013e31829cc6ae     Document Type: Article

References (34)

1. Mulroy MF, Larkin KL, Batra MS, Hodgson PS, Owens BD. Femoral nerve block with 0.25% or 0.5% bupivacaine improves postoperative analgesia following outpatient arthroscopic anterior cruciate ligament repair. Reg Anesth Pain Med 2001;26:24-9
2. Candido KD, Winnie AP, Ghaleb AH, Fattouh MW, Franco CD. Buprenorphine added to the local anesthetic for axillary brachial plexus block prolongs postoperative analgesia. Reg Anesth Pain Med 2002;27:162-7
3. Movafegh A, Nouralishahi B, Sadeghi M, Nabavian O. An ultra-low dose of naloxone added to lidocaine or lidocainefentanyl mixture prolongs axillary brachial plexus blockade. Anesth Analg 2009;109:1679-83
4. McCartney CJ, Duggan E, Apatu E. Should we add clonidine to local anesthetic for peripheral nerve blockade? A qualitative systematic review of the literature. Reg Anesth Pain Med 2007;32:330-8
5. Movafegh A, Razazian M, Hajimaohamadi F, Meysamie A. Dexamethasone added to lidocaine prolongs axillary brachial plexus blockade. Anesth Analg 2006;102:263-7
6. Rose JS, Neal JM, Kopacz DJ. Extended-duration analgesia: update on microspheres and liposomes. Reg Anesth Pain Med 2005;30:275-85
7. Grant GJ, Bansinath M. Liposomal delivery systems for local anesthetics. Reg Anesth Pain Med 2001;26:61-3
8. Gesztes A, Mezei M. Topical anesthesia of the skin by liposomeencapsulated tetracaine. Anesth Analg 1988;67:1079-81
9. Hung OR, Comeau L, Riley MR, Tan S, Whynot S, Mezei M. Comparative topical anaesthesia of EMLA and liposomeencapsulated tetracaine. Can J Anaesth 1997;44:707-11
10. Eichenfield LF, Funk A, Fallon-Friedlander S, Cunningham BB. A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children. Pediatrics 2002;109:1093-9
11. Holte K, Werner MU, Lacouture PG, Kehlet H. Dexamethasone prolongs local analgesia after subcutaneous infiltration of bupivacaine microcapsules in human volunteers. Anesthesiology 2002;96:1331-5
12. Kopacz DJ, Bernards CM, Allen HW, Landau C, Nandy P, Wu D, Lacouture PG. A model to evaluate the pharmacokinetic and pharmacodynamic variables of extended-release products using in vivo tissue microdialysis in humans: bupivacaineloaded microcapsules. Anesth Analg 2003;97:124-31
13. Pedersen JL, Lillesø J, Hammer NA, Werner MU, Holte K, Lacouture PG, Kehlet H. Bupivacaine in microcapsules prolongs analgesia after subcutaneous infiltration in humans: a dose-finding study. Anesth Analg 2004;99:912-8
14. Boogaerts JG, Lafont ND, Declercq AG, Luo HC, Gravet ET, Bianchi JA, Legros FJ. Epidural administration of liposomeassociated bupivacaine for the management of postsurgical pain: a first study. J Clin Anesth 1994;6:315-20
15. Lafont ND, Legros FJ, Boogaerts JG. Use of liposome-associated bupivacaine in a cancer pain syndrome. Anaesthesia 1996;51:578-9
16. Kopacz DJ, Lacouture PG, Wu D, Nandy P, Swanton R, Landau C. The dose response and effects of dexamethasone on bupivacaine microcapsules for intercostal blockade (T9 to T11) in healthy volunteers. Anesth Analg 2003;96:576-82
17. Viscusi ER. Liposomal drug delivery for postoperative pain management. Reg Anesth Pain Med 2005;30:491-6
18. Richard BM, Rickert DE, Doolittle D, Mize A, Liu J, Lawson CF. Pharmacokinetic Compatibility Study of Lidocaine with EXPAREL in Yucatan Miniature Pigs. ISRN Pharm 2011;2011:582351
19. Richard BM, Rickert DE, Newton PE, Ott LR, Haan D, Brubaker AN, Cole PI, Ross PE, Rebelatto MC, Nelson KG. Safety Evaluation of EXPAREL (DepoFoam Bupivacaine) Administered by Repeated Subcutaneous Injection in Rabbits and Dogs: Species Comparison. J Drug Deliv 2011;2011:467429
20. Bergese SD, Ramamoorthy S, Patou G, Bramlett K, Gorfine SR, Candiotti KA. Efficacy profile of liposome bupivacaine, a novel formulation of bupivacaine for postsurgical analgesia. J Pain Res 2012;5:107-16
21. Richard BM, Newton P, Ott LR, Haan D, Brubaker AN, Cole PI, Ross PE, Rebelatto MC, Nelson KG. The Safety of EXPAREL (Bupivacaine Liposome Injectable Suspension) Administered by Peripheral Nerve Block in Rabbits and Dogs. J Drug Deliv 2012;2012:962101
22. The Common Rule, Title 45 (Public Welfare), Code of Federal Regulations, Part 46 (Protection of Human Subjects), 2001:1-18
23. Stevens JE, Mizner RL, Snyder-Mackler L. Quadriceps strength and volitional activation before and after total knee arthroplasty for osteoarthritis. J Orthop Res 2003;21:775-9
24. Salinas FV, Neal JM, Sueda LA, Kopacz DJ, Liu SS. Prospective comparison of continuous femoral nerve block with nonstimulating catheter placement versus stimulating catheter-guided perineural placement in volunteers. Reg Anesth Pain Med 2004;29:212-20
25. Kwoh CK, Petrick MA, Munin MC. Inter-rater reliability for function and strength measurements in the acute care hospital after elective hip and knee arthroplasty. Arthritis Care Res 1997;10:128-34
26. Roy MA, Doherty TJ. Reliability of hand-held dynamometry in assessment of knee extensor strength after hip fracture. Am J Phys Med Rehabil 2004;83:813-8
27. Bohannon RW. Measuring knee extensor muscle strength. Am J Phys Med Rehabil 2001;80:13-8
28. Krishnan C, Williams GN. Evoked tetanic torque and activation level explain strength differences by side. Eur J Appl Physiol 2009;106:769-74
29. Ostenberg A, Roos E, Ekdahl C, Roos H. Isokinetic knee extensor strength and functional performance in healthy female soccer players. Scand J Med Sci Sports 1998;8:257-64
30. Ilfeld BM, Moeller LK, Mariano ER, Loland VJ, Stevens-Lapsley JE, Fleisher AS, Girard PJ, Donohue MC, Ferguson EJ, Ball ST. Continuous peripheral nerve blocks: is local anesthetic dose the only factor, or do concentration and volume influence infusion effects as well? Anesthesiology 2010;112:347-54
31. Petersen-Felix S, Zbinden AM, Fischer M, Thomson DA. Isoflurane minimum alveolar concentration decreases during anesthesia and surgery. Anesthesiology 1993;79:959-65
32. Laird NM, Ware JH. Random-effects models for longitudinal data. Biometrics 1982;38:963-74
33. Pinheiro JCB, Douglas M. Mixed-Effects Models in S and S-PLUS. New York, NY: Springer, 2000
34. Ilfeld BM, Loland VJ, Sandhu NS, Suresh PJ, Bishop MJ, Donohue MC, Ferguson EJ, Madison SJ. Continuous femoral nerve blocks: the impact of catheter tip location relative to the femoral nerve (anterior versus posterior) on quadriceps weakness and cutaneous sensory block. Anesth Analg 2012;115:721-7