Acceleration of bone development and regeneration through the Wnt/β-catenin signaling pathway in mice heterozygously deficient for GSK-3β

Biochemical and Biophysical Research Communications

Volumn 440, Issue 4, 2013, Pages 677-682

  Arioka, Masaki ^a,b   Takahashi Yanaga, Fumi ^a   Sasaki, Masanori ^b   Yoshihara, Tatsuya ^a   Morimoto, Sachio ^a   Takashima, Akihiko ^c   Mori, Yoshihide ^b   Sasaguri, Toshiyuki ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

Bone regeneration; GSK 3 ; Wnt catenin signaling pathway

Indexed keywords

BETA CATENIN; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3BETA; MYC PROTEIN; TRANSCRIPTION FACTOR RUNX2; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE DEVELOPMENT; BONE INJURY; BONE MASS; BONE REGENERATION; CORTICAL BONE; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSSIFICATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRABECULAR BONE; WNT SIGNALING PATHWAY;

MUS;

EID: 84887053589     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.09.126     Document Type: Article

References (27)

1. C.Y. Logan, and R. Nusse The wnt signaling pathway in development and disease Annu. Rev. Cell Dev. Biol. 20 2004 781 810
2. G. Bain, T. Muller, X. Wang, and J. Papkoff Activated beta-catenin induces osteoblast differentiation of C3H10T1/2 cells and participates in BMP2 mediated signal transduction Biochem. Biophys. Res. Commun. 301 2003 84 91
3. J.J. Westendorf, R.A. Kahler, and T.M. Schroeder Wnt signaling in osteoblasts and bone diseases Gene 341 2004 19 39
4. G. Rawadi, B. Vayssiere, F. Dunn, R. Baron, and S. Roman-Roman BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a wnt autocrine loop J. Bone Miner. Res. 18 2003 1842 1853
5. A. Gambardella, C.K. Nagaraju, P.J. O'Shea, S.T. Mohanty, L. Kottam, J. Pilling, M. Sullivan, M. Djerbi, W. Koopmann, P.I. Croucher, and I. Bellantuono Glycogen synthase kinase-3alpha/beta inhibition promotes in vivo amplification of endogenous mesenchymal progenitors with osteogenic and adipogenic potential and their differentiation to the osteogenic lineage J. Bone Miner. Res. 26 2011 811 821
6. N.H. Kulkarni, J.E. Onyia, Q. Zeng, X. Tian, M. Liu, D.L. Halladay, C.A. Frolik, T. Engler, T. Wei, A. Kriauciunas, T.J. Martin, M. Sato, H.U. Bryant, and Y.L. Ma Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo J. Bone Miner. Res. 21 2006 910 920
7. R. Nakanishi, H. Akiyama, H. Kimura, B. Otsuki, M. Shimizu, T. Tsuboyama, and T. Nakamura Osteoblast-targeted expression of Sfrp4 in mice results in low bone mass J. Bone Miner. Res. 23 2008 271 277
8. P. Clement-Lacroix, M. Ai, F. Morvan, S. Roman-Roman, B. Vayssiere, C. Belleville, K. Estrera, M.L. Warman, R. Baron, and G. Rawadi Lrp5-independent activation of wnt signaling by lithium chloride increases bone formation and bone mass in mice Proc. Natl. Acad. Sci. USA 102 2005 17406 17411
9. A. Zamani, G.R. Omrani, and M.M. Nasab Lithium's effect on bone mineral density Bone 44 2009 331 334
10. F. Kugimiya, H. Kawaguchi, S. Ohba, N. Kawamura, M. Hirata, H. Chikuda, Y. Azuma, J.R. Woodgett, K. Nakamura, and U.I. Chung GSK-3beta controls osteogenesis through regulating Runx2 activity PLoS One 2 2007 e837
11. P. Ducy, R. Zhang, V. Geoffroy, A.L. Ridall, and G. Karsenty Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation Cell 89 1997 747 754
12. T. Komori, H. Yagi, S. Nomura, A. Yamaguchi, K. Sasaki, K. Deguchi, Y. Shimizu, R.T. Bronson, Y.H. Gao, M. Inada, M. Sato, R. Okamoto, Y. Kitamura, S. Yoshiki, and T. Kishimoto Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts Cell 89 1997 755 764
13. F. Otto, A.P. Thornell, T. Crompton, A. Denzel, K.C. Gilmour, I.R. Rosewell, G.W. Stamp, R.S. Beddington, S. Mundlos, B.R. Olsen, P.B. Selby, and M.J. Owen Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development Cell 89 1997 765 771
14. T. Kimura, S. Yamashita, S. Nakao, J.M. Park, M. Murayama, T. Mizoroki, Y. Yoshiike, N. Sahara, and A. Takashima GSK-3beta is required for memory reconsolidation in adult brain PLoS One 3 2008 e3540
15. F. Takahashi-Yanaga, Y. Taba, Y. Miwa, Y. Kubohara, Y. Watanabe, M. Hirata, S. Morimoto, and T. Sasaguri Dictyostelium differentiation-inducing factor-3 activates glycogen synthase kinase-3beta and degrades cyclin D1 in mammalian cells J. Biol. Chem. 278 2003 9663 9670
16. M.L. Bouxsein, S.K. Boyd, B.A. Christiansen, R.E. Guldberg, K.J. Jepsen, and R. Muller Guidelines for assessment of bone microstructure in rodents using micro-computed tomography J. Bone Miner. Res. 25 2010 1468 1486
17. O. Kaidanovich-Beilin, and J.R. Woodgett GSK-3: functional insights from cell biology and animal models Front. Mol. Neurosci. 4 2011 40
18. A. Kikuchi, H. Yamamoto, and S. Kishida Multiplicity of the interactions of wnt proteins and their receptors Cell. Signal. 19 2007 659 671
19. T. Gaur, C.J. Lengner, H. Hovhannisyan, R.A. Bhat, P.V. Bodine, B.S. Komm, A. Javed, A.J. van Wijnen, J.L. Stein, G.S. Stein, and J.B. Lian Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression J. Biol. Chem. 280 2005 33132 33140
20. Y. Gong, R.B. Slee, N. Fukai, G. Rawadi, S. Roman-Roman, A.M. Reginato, H. Wang, T. Cundy, F.H. Glorieux, D. Lev, M. Zacharin, K. Oexle, J. Marcelino, W. Suwairi, S. Heeger, G. Sabatakos, S. Apte, W.N. Adkins, J. Allgrove, M. Arslan-Kirchner, J.A. Batch, P. Beighton, G.C. Black, R.G. Boles, L.M. Boon, C. Borrone, H.G. Brunner, G.F. Carle, B. Dallapiccola, A. De Paepe, B. Floege, M.L. Halfhide, B. Hall, R.C. Hennekam, T. Hirose, A. Jans, H. Juppner, C.A. Kim, K. Keppler-Noreuil, A. Kohlschuetter, D. LaCombe, M. Lambert, E. Lemyre, T. Letteboer, L. Peltonen, R.S. Ramesar, M. Romanengo, H. Somer, E. Steichen-Gersdorf, B. Steinmann, B. Sullivan, A. Superti-Furga, W. Swoboda, M.J. van den Boogaard, W. Van Hul, M. Vikkula, M. Votruba, B. Zabel, T. Garcia, R. Baron, B.R. Olsen, and M.L. Warman Osteoporosis-Pseudoglioma Syndrome Collaborative Group. LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development Cell 107 2001 513 523
21. M.P. Whyte, W.H. Reinus, and S. Mumm High-bone-mass disease and LRP5 N. Engl. J. Med. 350 2004 2096 2099 author reply 2096-2099
22. M.L. Johnson, K. Harnish, R. Nusse, and W. Van Hul LRP5 and wnt signaling: a union made for bone J. Bone Miner. Res. 19 2004 1749 1757
23. F. Takahashi-Yanaga Activator or inhibitor? GSK-3 as a new drug target Biochem. Pharmacol. 86 2013 191 199
24. H. Eldar-Finkelman, and A. Martinez GSK-3 inhibitors: preclinical and clinical focus on CNS Front. Mol. Neurosci. 4 2011 32
25. B.W. Doble, S. Patel, G.A. Wood, L.K. Kockeritz, and J.R. Woodgett Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines Dev. Cell 12 2007 957 971
26. J. Zhou, T.A. Freeman, F. Ahmad, X. Shang, E. Mangano, E. Gao, J. Farber, Y. Wang, X.L. Ma, J. Woodgett, R.J. Vagnozzi, H. Lal, and T. Force GSK-3alpha is a central regulator of age-related pathologies in mice J. Clin. Invest. 123 2013 1821 1832
27. M. Schou Lithium treatment at 52 J. Affect. Disord. 67 2001 21 32