Identification of Mob2, a novel regulator of larval neuromuscular junction morphology, in natural populations of Drosophila melanogaster

Genetics

Volumn 195, Issue 3, 2013, Pages 915-926

  Campbell, Megan ^a   Ganetzky, Barry ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; MONOPOLAR SPINDLE ONE BINDING PROTEIN 2; UNCLASSIFIED DRUG;

ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; LARVA; NATURAL POPULATION; NEUROMUSCULAR SYNAPSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

DROSOPHILA MELANOGASTER;

BEHAVIOR; NATURAL VARIANTS; NEURAL EVOLUTION; NEURODEVELOPMENT; SYNAPSE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; GENES, INSECT; GENETIC VARIATION; GENETICS, POPULATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LARVA; MUTATION; NEUROMUSCULAR JUNCTION; PHENOTYPE; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES;

EID: 84887048419     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.113.156562     Document Type: Article

References (33)

1. Baillat, G., A. Moqrich, F. Castets, A. Baude, Y. Bailly et al., 2001 Molecular cloning and characterization of phoecein, a protein found from the Golgi complex to dendritic spines. Mol. Biol. Cell 12: 663-673.
2. Campbell, M., and B. Ganetzky, 2012 Extensive morphological divergence and rapid evolution of the larval neuromuscular junction in Drosophila. Proc. Natl. Acad. Sci. USA 109: E645-E655.
3. Carroll, S. B., 2005 Evolution at two levels: on genes and form. PLoS Biol. 3: e245.
4. Collins, C. A., and A. DiAntonio, 2007 Synaptic development: insights from Drosophila. Curr. Opin. Neurobiol. 17: 35-42.
5. Coyle, I. P., Y. H. Koh, W. C. Lee, J. Slind, T. Fergestad et al., 2004 Nervous Wreck, an SH3 adaptor protein that interacts with Wsp, regulates synaptic growth in Drosophila. Neuron 41: 521-534.
6. Dawson-Scully, K., G. A. Armstrong, C. Kent, R. M. Robertson, and M. B. Sokolowski, 2007 Natural variation in the thermotolerance of neural function and behavior due to a cGMP-dependent protein kinase. PLoS ONE 2: e773.
7. Ebert, D. H., and M. E. Greenberg, 2013 Activity-dependent neuronal signaling and autism spectrum disorders. Nature 493: 327-337.
8. Emoto, K., Y. He, B. Ye, W. B. Grueber, P. N. Adler et al., 2004 Control of dendritic branching and tiling by the Tricornered-kinase/Fury signaling pathway in Drosophila sensory neurons. Cell 119: 245-256.
9. Emoto, K., J. Z. Parrish, L. Y. Jan, and Y. N. Jan, 2006 The tumor suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance. Nature 443: 210-213.
10. He, Y., K. Emoto, C. Fang, N. Ren, X. Tian et al., 2005 Drosophila Mob family proteins interact with the related Tricornered (Trc) and Warts (Wts) kinases. Mol. Biol. Cell 16: 4139-4152.
11. Hergovich, A., 2011 MOB control: reviewing a conserved family of kinase regulators. Cell. Signal. 23: 1433-1440.
12. Houser, C. R., N. Zhang, Z. Peng, C. S. Huang, and Y. Cetina, 2012 Neuroanatomical clues to altered neuronal activity in epilepsy: from ultrastructure to signaling pathways of dentate granule cells. Epilepsia 53(Suppl 1): 67-77.
13. Katzenberger, R., M. A. Marengo, and D. A. Wassarman, 2006 ATM and ATR pathways signal alternative splicing of Drosophila TAF1 Pre-mRNA in response to DNA damage. Mol. Cell. Biol. 26: 9256-9267.
14. Krueger, D. D., L. P. Tuffy, T. Papadopoulos, and N. Brose, 2012 The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses. Curr. Opin. Neurobiol. 22: 412-422.
15. Lai, Z. C., X. Wei, T. Shimizu, E. Ramos, M. Rohrbaugh et al., 2005 Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell 120: 675-685.
16. Levenga, J., and R. Willemsen, 2012 Perturbation of dendritic protrusions in intellectual disability. Prog. Brain Res. 197: 153-168.
17. Li, H., A. Coghlan, J. Ruan, L. J. Coin, J. K. Heriche et al., 2006 TreeFam: a curated database of phylogenetic trees of animal gene families. Nucleic Acid Res. 34: D572-D580.
18. Lin, C. H., M. Hsieh, and S. S. Fan, 2011 The promotion of neurite formation in Neuro2A cells by mouse Mob2 protein. FEBS Lett. 585: 523-530.
19. Liu, L.-Y., C.-H. Lin, and S.-S. Fan, 2009 Function of Drosophila mob2 in photoreceptor morphogenesis. Cell Tissue Res. 338: 377-389.
20. Luca, F. C., and M. Winey, 1998 MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy. Mol. Biol. Cell 9: 29-46.
21. Mrkobrada S., L. Boucher, D. F. Ceccarelli, M. Tyers, and F. Sicheri, 2006 Structural and functional analysis of Saccaromyces cerevisiae Mob1. J. Mol. Biol. 362: 430-40.
22. Nelson, B., C. Kurischko, J. Horecka, M. Mody, P. Nair et al., 2003 RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Mol. Biol. Cell 14: 3782-3803.
23. Peça, J., and G. Feng, 2012 Cellular and synaptic network defects in autism. Curr. Opin. Neurobiol. 22: 866-872.
24. Russo, C. A. M., N. Takezaki, and M. Nei, 1995 Molecular Phylogeny and Divergence Times of Drosophilid Species. Mol. Biol. Evol. 12: 391-404.
25. Ryan, T. J., and S. G. N. Grant, 2009 The origin and evolution of synapses. Nat. Rev. Neurosci. 10: 701-712.
26. Sandler, L., D. L. Lindsley, B. Nicoletti, and G. Trippa, 1968 Mutants affecting meiosis in natural populations of Drosophila melanogaster. Genetics 60: 525-558.
27. Sawyer, L. A., J. Hennessy, A. A. Peixoto, E. Rosato, H. Parkinson et al., 1997 Natural variation in a Drosophila clock gene and temperature compensation. Science 278: 2117-2120.
28. Schulte, J., K. J. Sepp, R. A. Jorquera, C. Wu, Y. Song et al., 2010 DMob4/Phocein regulates synapse formation, axonal transport, and microtubule organization. J. Neurosci. 30: 5189-5203.
29. Shimizu, T., L. L. Ho, and Z. C. Lai, 2008 The mob as tumor suppressor gene is essential for early development and regulates tissue growth in Drosophila. Genetics 178: 957-965.
30. Stern, D. L., and V. Orgogozo, 2009 Is genetic evolution predictable? Science 323: 746-751.
31. Trammell, M. A., N. M. Mahoney, D. A. Agard, and R. D. Vale, 2008 Mob4 plays a role in spindle focusing in Drosophila S2 cells. J. Cell Sci. 121: 1284-1292.
32. Weiss, E. L., C. Kurischko, C. Zhang, K. Shokat, D. G. Drubin et al., 2002 The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2 transcription factor. J. Cell Biol. 158: 885-900.
33. West, A. E., and M. E. Greenberg, 2011 Neuronal activity-regulated gene transcription in synapse development and cognitive function. Cold Spring Harb. Perspect. Biol. 3: 1-21.