메뉴 건너뛰기




Volumn 10, Issue 1, 2013, Pages

Efficient BST2 antagonism by Vpu is critical for early HIV-1 dissemination in humanized mice

Author keywords

BST2; HIV 1 release; Humanized mice; Viral dissemination; Vpu

Indexed keywords

BST2 PROTEIN; CHEMOKINE RECEPTOR CCR5; HOST FACTOR; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VPU PROTEIN;

EID: 84887041456     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-10-128     Document Type: Article
Times cited : (39)

References (50)
  • 1
    • 84866492666 scopus 로고    scopus 로고
    • Intrinsic cellular defenses against human immunodeficiency viruses
    • 10.1016/j.immuni.2012.08.013, 22999946
    • Blanco-Melo D, Venkatesh S, Bieniasz PD. Intrinsic cellular defenses against human immunodeficiency viruses. Immunity 2012, 37:399-411. 10.1016/j.immuni.2012.08.013, 22999946.
    • (2012) Immunity , vol.37 , pp. 399-411
    • Blanco-Melo, D.1    Venkatesh, S.2    Bieniasz, P.D.3
  • 2
    • 84870335313 scopus 로고    scopus 로고
    • The restriction factors of human immunodeficiency virus
    • 10.1074/jbc.R112.416925, 23043100
    • Harris RS, Hultquist JF, Evans DT. The restriction factors of human immunodeficiency virus. J Biol Chem 2012, 287:40875-40883. 10.1074/jbc.R112.416925, 23043100.
    • (2012) J Biol Chem , vol.287 , pp. 40875-40883
    • Harris, R.S.1    Hultquist, J.F.2    Evans, D.T.3
  • 3
    • 33747803946 scopus 로고    scopus 로고
    • Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation
    • Blasius AL, Giurisato E, Cella M, Schreiber RD, Shaw AS, Colonna M. Bone marrow stromal cell antigen 2 is a specific marker of type I IFN-producing cells in the naive mouse, but a promiscuous cell surface antigen following IFN stimulation. J Immunol 2006, 177:3260-3265.
    • (2006) J Immunol , vol.177 , pp. 3260-3265
    • Blasius, A.L.1    Giurisato, E.2    Cella, M.3    Schreiber, R.D.4    Shaw, A.S.5    Colonna, M.6
  • 4
    • 38549095979 scopus 로고    scopus 로고
    • Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
    • 10.1038/nature06553, 18200009
    • Neil SJ, Zang T, Bieniasz PD. Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature 2008, 451:425-430. 10.1038/nature06553, 18200009.
    • (2008) Nature , vol.451 , pp. 425-430
    • Neil, S.J.1    Zang, T.2    Bieniasz, P.D.3
  • 5
    • 41849116366 scopus 로고    scopus 로고
    • The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein
    • 10.1016/j.chom.2008.03.001, 2474773, 18342597
    • Van Damme N, Goff D, Katsura C, Jorgenson RL, Mitchell R, Johnson MC, Stephens EB, Guatelli J. The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host Microbe 2008, 3:245-252. 10.1016/j.chom.2008.03.001, 2474773, 18342597.
    • (2008) Cell Host Microbe , vol.3 , pp. 245-252
    • Van Damme, N.1    Goff, D.2    Katsura, C.3    Jorgenson, R.L.4    Mitchell, R.5    Johnson, M.C.6    Stephens, E.B.7    Guatelli, J.8
  • 6
    • 84855267408 scopus 로고    scopus 로고
    • Quantitative multicolor super-resolution microscopy reveals tetherin HIV-1 interaction
    • 10.1371/journal.ppat.1002456, 3240612, 22194693
    • Lehmann M, Rocha S, Mangeat B, Blanchet F, Uji IH, Hofkens J, Piguet V. Quantitative multicolor super-resolution microscopy reveals tetherin HIV-1 interaction. PLoS Pathog 2011, 7:e1002456. 10.1371/journal.ppat.1002456, 3240612, 22194693.
    • (2011) PLoS Pathog , vol.7
    • Lehmann, M.1    Rocha, S.2    Mangeat, B.3    Blanchet, F.4    Uji, I.H.5    Hofkens, J.6    Piguet, V.7
  • 7
    • 84884795357 scopus 로고    scopus 로고
    • Mechanism of HIV-1 virion entrapment by tetherin
    • 10.1371/journal.ppat.1003483, 3715405, 23874200
    • Venkatesh S, Bieniasz PD. Mechanism of HIV-1 virion entrapment by tetherin. PLoS Pathog 2013, 9:e1003483. 10.1371/journal.ppat.1003483, 3715405, 23874200.
    • (2013) PLoS Pathog , vol.9
    • Venkatesh, S.1    Bieniasz, P.D.2
  • 9
    • 78049521946 scopus 로고    scopus 로고
    • Cell-cell spread of human immunodeficiency virus type 1 overcomes tetherin/BST-2-mediated restriction in T cells
    • 10.1128/JVI.01447-10, 2976402, 20861257
    • Jolly C, Booth NJ, Neil SJ. Cell-cell spread of human immunodeficiency virus type 1 overcomes tetherin/BST-2-mediated restriction in T cells. J Virol 2010, 84:12185-12199. 10.1128/JVI.01447-10, 2976402, 20861257.
    • (2010) J Virol , vol.84 , pp. 12185-12199
    • Jolly, C.1    Booth, N.J.2    Neil, S.J.3
  • 10
    • 84861206974 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in < italic > tetherin promotes retrovirus restriction < italic > in vivo
    • 10.1371/journal.ppat.1002596, 3310811, 22457621
    • Barrett BS, Smith DS, Li SX, Guo K, Hasenkrug KJ, Santiago ML. A single nucleotide polymorphism in < italic > tetherin promotes retrovirus restriction < italic > in vivo. PLoS Pathog 2012, 8:e1002596. 10.1371/journal.ppat.1002596, 3310811, 22457621.
    • (2012) PLoS Pathog , vol.8
    • Barrett, B.S.1    Smith, D.S.2    Li, S.X.3    Guo, K.4    Hasenkrug, K.J.5    Santiago, M.L.6
  • 11
    • 81055145390 scopus 로고    scopus 로고
    • Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo
    • 10.1073/pnas.1113694108, 3207693, 22025715
    • Liberatore RA, Bieniasz PD. Tetherin is a key effector of the antiretroviral activity of type I interferon in vitro and in vivo. Proc Natl Acad Sci U S A 2011, 108:18097-18101. 10.1073/pnas.1113694108, 3207693, 22025715.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 18097-18101
    • Liberatore, R.A.1    Bieniasz, P.D.2
  • 12
    • 78649401965 scopus 로고    scopus 로고
    • Determinants of tetherin antagonism in the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein
    • 10.1128/JVI.01699-10, 3004320, 20926557
    • Vigan R, Neil SJ. Determinants of tetherin antagonism in the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein. J Virol 2010, 84:12958-12970. 10.1128/JVI.01699-10, 3004320, 20926557.
    • (2010) J Virol , vol.84 , pp. 12958-12970
    • Vigan, R.1    Neil, S.J.2
  • 13
    • 84876864784 scopus 로고    scopus 로고
    • Vpu binds directly to tetherin and displaces it from nascent virions
    • 10.1371/journal.ppat.1003299, 3635990, 23633949
    • McNatt MW, Zang T, Bieniasz PD. Vpu binds directly to tetherin and displaces it from nascent virions. PLoS Pathog 2013, 9:e1003299. 10.1371/journal.ppat.1003299, 3635990, 23633949.
    • (2013) PLoS Pathog , vol.9
    • McNatt, M.W.1    Zang, T.2    Bieniasz, P.D.3
  • 14
    • 84855272482 scopus 로고    scopus 로고
    • HIV-1 Vpu protein antagonizes innate restriction factor BST-2 via lipid-embedded helix-helix interactions
    • 10.1074/jbc.M111.296772, 3249111, 22072710
    • Skasko M, Wang Y, Tian Y, Tokarev A, Munguia J, Ruiz A, Stephens EB, Opella SJ, Guatelli J. HIV-1 Vpu protein antagonizes innate restriction factor BST-2 via lipid-embedded helix-helix interactions. J Biol Chem 2012, 287:58-67. 10.1074/jbc.M111.296772, 3249111, 22072710.
    • (2012) J Biol Chem , vol.287 , pp. 58-67
    • Skasko, M.1    Wang, Y.2    Tian, Y.3    Tokarev, A.4    Munguia, J.5    Ruiz, A.6    Stephens, E.B.7    Opella, S.J.8    Guatelli, J.9
  • 16
    • 77954055324 scopus 로고    scopus 로고
    • Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment
    • 10.1371/journal.ppat.1000856, 2851737, 20386718
    • Dube M, Roy BB, Guiot-Guillain P, Binette J, Mercier J, Chiasson A, Cohen EA. Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment. PLoS Pathog 2010, 6:e1000856. 10.1371/journal.ppat.1000856, 2851737, 20386718.
    • (2010) PLoS Pathog , vol.6
    • Dube, M.1    Roy, B.B.2    Guiot-Guillain, P.3    Binette, J.4    Mercier, J.5    Chiasson, A.6    Cohen, E.A.7
  • 17
    • 81055156009 scopus 로고    scopus 로고
    • HIV-1 Vpu antagonizes BST-2 by interfering mainly with the trafficking of newly synthesized BST-2 to the cell surface
    • 10.1111/j.1600-0854.2011.01277.x, 21902775
    • Dube M, Paquay C, Roy BB, Bego MG, Mercier J, Cohen EA. HIV-1 Vpu antagonizes BST-2 by interfering mainly with the trafficking of newly synthesized BST-2 to the cell surface. Traffic 2011, 12:1714-1729. 10.1111/j.1600-0854.2011.01277.x, 21902775.
    • (2011) Traffic , vol.12 , pp. 1714-1729
    • Dube, M.1    Paquay, C.2    Roy, B.B.3    Bego, M.G.4    Mercier, J.5    Cohen, E.A.6
  • 18
    • 77953044868 scopus 로고    scopus 로고
    • HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment
    • 10.1186/1742-4690-7-51, 2890665, 20529266
    • Hauser H, Lopez LA, Yang SJ, Oldenburg JE, Exline CM, Guatelli JC, Cannon PM. HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment. Retrovirology 2010, 7:51. 10.1186/1742-4690-7-51, 2890665, 20529266.
    • (2010) Retrovirology , vol.7 , pp. 51
    • Hauser, H.1    Lopez, L.A.2    Yang, S.J.3    Oldenburg, J.E.4    Exline, C.M.5    Guatelli, J.C.6    Cannon, P.M.7
  • 19
    • 0032012456 scopus 로고    scopus 로고
    • A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif
    • 10.1016/S1097-2765(00)80056-8, 9660940
    • Margottin F, Bour SP, Durand H, Selig L, Benichou S, Richard V, Thomas D, Strebel K, Benarous R. A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif. Mol Cell 1998, 1:565-574. 10.1016/S1097-2765(00)80056-8, 9660940.
    • (1998) Mol Cell , vol.1 , pp. 565-574
    • Margottin, F.1    Bour, S.P.2    Durand, H.3    Selig, L.4    Benichou, S.5    Richard, V.6    Thomas, D.7    Strebel, K.8    Benarous, R.9
  • 20
    • 78650038839 scopus 로고    scopus 로고
    • Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu
    • 10.1128/JVI.01795-10, 3014196, 20980512
    • Tokarev AA, Munguia J, Guatelli JC. Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu. J Virol 2011, 85:51-63. 10.1128/JVI.01795-10, 3014196, 20980512.
    • (2011) J Virol , vol.85 , pp. 51-63
    • Tokarev, A.A.1    Munguia, J.2    Guatelli, J.C.3
  • 21
    • 84860354388 scopus 로고    scopus 로고
    • Ubiquitination of BST-2 protein by HIV-1 Vpu protein does not require lysine, serine, or threonine residues within the BST-2 cytoplasmic domain
    • 10.1074/jbc.M112.349928, 3340234, 22383521
    • Gustin JK, Douglas JL, Bai Y, Moses AV. Ubiquitination of BST-2 protein by HIV-1 Vpu protein does not require lysine, serine, or threonine residues within the BST-2 cytoplasmic domain. J Biol Chem 2012, 287:14837-14850. 10.1074/jbc.M112.349928, 3340234, 22383521.
    • (2012) J Biol Chem , vol.287 , pp. 14837-14850
    • Gustin, J.K.1    Douglas, J.L.2    Bai, Y.3    Moses, A.V.4
  • 22
    • 77954043624 scopus 로고    scopus 로고
    • The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin
    • 10.1371/journal.ppat.1000843, 2855335, 20419159
    • Pardieu C, Vigan R, Wilson SJ, Calvi A, Zang T, Bieniasz P, Kellam P, Towers GJ, Neil SJ. The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin. PLoS Pathog 2010, 6:e1000843. 10.1371/journal.ppat.1000843, 2855335, 20419159.
    • (2010) PLoS Pathog , vol.6
    • Pardieu, C.1    Vigan, R.2    Wilson, S.J.3    Calvi, A.4    Zang, T.5    Bieniasz, P.6    Kellam, P.7    Towers, G.J.8    Neil, S.J.9
  • 23
    • 67749095196 scopus 로고    scopus 로고
    • Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism
    • 10.1128/JVI.00242-09, 2715753, 19515779
    • Douglas JL, Viswanathan K, McCarroll MN, Gustin JK, Fruh K, Moses AV. Vpu directs the degradation of the human immunodeficiency virus restriction factor BST-2/Tetherin via a {beta}TrCP-dependent mechanism. J Virol 2009, 83:7931-7947. 10.1128/JVI.00242-09, 2715753, 19515779.
    • (2009) J Virol , vol.83 , pp. 7931-7947
    • Douglas, J.L.1    Viswanathan, K.2    McCarroll, M.N.3    Gustin, J.K.4    Fruh, K.5    Moses, A.V.6
  • 24
    • 79751526122 scopus 로고    scopus 로고
    • Beta-TrCP is dispensable for Vpu's ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release
    • 10.1186/1742-4690-8-9, 3049139, 21310048
    • Tervo HM, Homann S, Ambiel I, Fritz JV, Fackler OT, Keppler OT. beta-TrCP is dispensable for Vpu's ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release. Retrovirology 2011, 8:9. 10.1186/1742-4690-8-9, 3049139, 21310048.
    • (2011) Retrovirology , vol.8 , pp. 9
    • Tervo, H.M.1    Homann, S.2    Ambiel, I.3    Fritz, J.V.4    Fackler, O.T.5    Keppler, O.T.6
  • 25
    • 84861209115 scopus 로고    scopus 로고
    • A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction
    • 10.1371/journal.ppat.1002609, 3315493, 22479182
    • Kueck T, Neil SJ. A cytoplasmic tail determinant in HIV-1 Vpu mediates targeting of tetherin for endosomal degradation and counteracts interferon-induced restriction. PLoS Pathog 2012, 8:e1002609. 10.1371/journal.ppat.1002609, 3315493, 22479182.
    • (2012) PLoS Pathog , vol.8
    • Kueck, T.1    Neil, S.J.2
  • 26
    • 77950495072 scopus 로고    scopus 로고
    • Antagonism of CD317 restriction of human immunodeficiency virus type 1 (HIV-1) particle release and depletion of CD317 are separable activities of HIV-1 Vpu
    • 10.1128/JVI.01549-09, 2849503, 20147395
    • Goffinet C, Homann S, Ambiel I, Tibroni N, Rupp D, Keppler OT, Fackler OT. Antagonism of CD317 restriction of human immunodeficiency virus type 1 (HIV-1) particle release and depletion of CD317 are separable activities of HIV-1 Vpu. J Virol 2010, 84:4089-4094. 10.1128/JVI.01549-09, 2849503, 20147395.
    • (2010) J Virol , vol.84 , pp. 4089-4094
    • Goffinet, C.1    Homann, S.2    Ambiel, I.3    Tibroni, N.4    Rupp, D.5    Keppler, O.T.6    Fackler, O.T.7
  • 27
    • 76949106980 scopus 로고    scopus 로고
    • Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue
    • 10.1186/1742-4690-7-1, 2823648, 20078884
    • Schindler M, Rajan D, Banning C, Wimmer P, Koppensteiner H, Iwanski A, Specht A, Sauter D, Dobner T, Kirchhoff F. Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue. Retrovirology 2010, 7:1. 10.1186/1742-4690-7-1, 2823648, 20078884.
    • (2010) Retrovirology , vol.7 , pp. 1
    • Schindler, M.1    Rajan, D.2    Banning, C.3    Wimmer, P.4    Koppensteiner, H.5    Iwanski, A.6    Specht, A.7    Sauter, D.8    Dobner, T.9    Kirchhoff, F.10
  • 28
    • 66149099203 scopus 로고    scopus 로고
    • Suppression of Tetherin-restricting activity upon human immunodeficiency virus type 1 particle release correlates with localization of Vpu in the trans-Golgi network
    • 10.1128/JVI.01800-08, 2668474, 19244337
    • Dube M, Roy BB, Guiot-Guillain P, Mercier J, Binette J, Leung G, Cohen EA. Suppression of Tetherin-restricting activity upon human immunodeficiency virus type 1 particle release correlates with localization of Vpu in the trans-Golgi network. J Virol 2009, 83:4574-4590. 10.1128/JVI.01800-08, 2668474, 19244337.
    • (2009) J Virol , vol.83 , pp. 4574-4590
    • Dube, M.1    Roy, B.B.2    Guiot-Guillain, P.3    Mercier, J.4    Binette, J.5    Leung, G.6    Cohen, E.A.7
  • 29
    • 37749032764 scopus 로고    scopus 로고
    • Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum
    • 10.1186/1742-4690-4-75, 2170451, 17937819
    • Binette J, Dube M, Mercier J, Halawani D, Latterich M, Cohen EA. Requirements for the selective degradation of CD4 receptor molecules by the human immunodeficiency virus type 1 Vpu protein in the endoplasmic reticulum. Retrovirology 2007, 4:75. 10.1186/1742-4690-4-75, 2170451, 17937819.
    • (2007) Retrovirology , vol.4 , pp. 75
    • Binette, J.1    Dube, M.2    Mercier, J.3    Halawani, D.4    Latterich, M.5    Cohen, E.A.6
  • 30
    • 0026452726 scopus 로고
    • Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4
    • 240416, 1433512
    • Willey RL, Maldarelli F, Martin MA, Strebel K. Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4. J Virol 1992, 66:7193-7200. 240416, 1433512.
    • (1992) J Virol , vol.66 , pp. 7193-7200
    • Willey, R.L.1    Maldarelli, F.2    Martin, M.A.3    Strebel, K.4
  • 31
    • 77954047969 scopus 로고    scopus 로고
    • Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps
    • 10.1371/journal.ppat.1000869, 2861688, 20442859
    • Magadan JG, Perez-Victoria FJ, Sougrat R, Ye Y, Strebel K, Bonifacino JS. Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps. PLoS Pathog 2010, 6:e1000869. 10.1371/journal.ppat.1000869, 2861688, 20442859.
    • (2010) PLoS Pathog , vol.6
    • Magadan, J.G.1    Perez-Victoria, F.J.2    Sougrat, R.3    Ye, Y.4    Strebel, K.5    Bonifacino, J.S.6
  • 32
    • 0033578072 scopus 로고    scopus 로고
    • Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner
    • 10.1016/S0960-9822(99)80284-X, 10375528
    • Lama J, Mangasarian A, Trono D. Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner. Curr Biol 1999, 9:622-631. 10.1016/S0960-9822(99)80284-X, 10375528.
    • (1999) Curr Biol , vol.9 , pp. 622-631
    • Lama, J.1    Mangasarian, A.2    Trono, D.3
  • 33
    • 0042346262 scopus 로고    scopus 로고
    • Vpu exerts a positive effect on HIV-1 infectivity by down-modulating CD4 receptor molecules at the surface of HIV-1-producing cells
    • 10.1074/jbc.M300327200, 12746459
    • Levesque K, Zhao YS, Cohen EA. Vpu exerts a positive effect on HIV-1 infectivity by down-modulating CD4 receptor molecules at the surface of HIV-1-producing cells. J Biol Chem 2003, 278:28346-28353. 10.1074/jbc.M300327200, 12746459.
    • (2003) J Biol Chem , vol.278 , pp. 28346-28353
    • Levesque, K.1    Zhao, Y.S.2    Cohen, E.A.3
  • 34
    • 33746799703 scopus 로고    scopus 로고
    • Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection
    • 10.1128/JVI.00252-06, 1563805, 16873261
    • Wildum S, Schindler M, Munch J, Kirchhoff F. Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection. J Virol 2006, 80:8047-8059. 10.1128/JVI.00252-06, 1563805, 16873261.
    • (2006) J Virol , vol.80 , pp. 8047-8059
    • Wildum, S.1    Schindler, M.2    Munch, J.3    Kirchhoff, F.4
  • 35
    • 78349264184 scopus 로고    scopus 로고
    • Degranulation of natural killer cells following interaction with HIV-1-infected cells is hindered by downmodulation of NTB-A by Vpu
    • 10.1016/j.chom.2010.10.008, 3005698, 21075351
    • Shah AH, Sowrirajan B, Davis ZB, Ward JP, Campbell EM, Planelles V, Barker E. Degranulation of natural killer cells following interaction with HIV-1-infected cells is hindered by downmodulation of NTB-A by Vpu. Cell Host Microbe 2010, 8:397-409. 10.1016/j.chom.2010.10.008, 3005698, 21075351.
    • (2010) Cell Host Microbe , vol.8 , pp. 397-409
    • Shah, A.H.1    Sowrirajan, B.2    Davis, Z.B.3    Ward, J.P.4    Campbell, E.M.5    Planelles, V.6    Barker, E.7
  • 36
    • 84861391185 scopus 로고    scopus 로고
    • The human immunodeficiency virus type 1 Nef and Vpu proteins downregulate the natural killer cell-activating ligand PVR
    • 10.1128/JVI.05788-11, 3318642, 22301152
    • Matusali G, Potesta M, Santoni A, Cerboni C, Doria M. The human immunodeficiency virus type 1 Nef and Vpu proteins downregulate the natural killer cell-activating ligand PVR. J Virol 2012, 86:4496-4504. 10.1128/JVI.05788-11, 3318642, 22301152.
    • (2012) J Virol , vol.86 , pp. 4496-4504
    • Matusali, G.1    Potesta, M.2    Santoni, A.3    Cerboni, C.4    Doria, M.5
  • 37
    • 84861321795 scopus 로고    scopus 로고
    • Vpu augments the initial burst phase of HIV-1 propagation and downregulates BST2 and CD4 in humanized mice
    • 10.1128/JVI.07062-11, 3347374, 22357275
    • Sato K, Misawa N, Fukuhara M, Iwami S, An DS, Ito M, Koyanagi Y. Vpu augments the initial burst phase of HIV-1 propagation and downregulates BST2 and CD4 in humanized mice. J Virol 2012, 86:5000-5013. 10.1128/JVI.07062-11, 3347374, 22357275.
    • (2012) J Virol , vol.86 , pp. 5000-5013
    • Sato, K.1    Misawa, N.2    Fukuhara, M.3    Iwami, S.4    An, D.S.5    Ito, M.6    Koyanagi, Y.7
  • 38
    • 77957582392 scopus 로고    scopus 로고
    • Innate immune activation in primary HIV-1 infection
    • 10.1086/655657, 2945608, 20846036
    • Chang JJ, Altfeld M. Innate immune activation in primary HIV-1 infection. J Infect Dis 2010, 202:S297-S301. 10.1086/655657, 2945608, 20846036.
    • (2010) J Infect Dis , vol.202
    • Chang, J.J.1    Altfeld, M.2
  • 39
    • 33846036832 scopus 로고    scopus 로고
    • Inefficient human immunodeficiency virus replication in mobile lymphocytes
    • 10.1128/JVI.01629-06, 1797449, 17079292
    • Sourisseau M, Sol-Foulon N, Porrot F, Blanchet F, Schwartz O. Inefficient human immunodeficiency virus replication in mobile lymphocytes. J Virol 2007, 81:1000-1012. 10.1128/JVI.01629-06, 1797449, 17079292.
    • (2007) J Virol , vol.81 , pp. 1000-1012
    • Sourisseau, M.1    Sol-Foulon, N.2    Porrot, F.3    Blanchet, F.4    Schwartz, O.5
  • 40
    • 36049037370 scopus 로고    scopus 로고
    • Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses
    • 10.1128/JVI.00381-07, 2169007, 17728240
    • Chen P, Hubner W, Spinelli MA, Chen BK. Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses. J Virol 2007, 81:12582-12595. 10.1128/JVI.00381-07, 2169007, 17728240.
    • (2007) J Virol , vol.81 , pp. 12582-12595
    • Chen, P.1    Hubner, W.2    Spinelli, M.A.3    Chen, B.K.4
  • 41
    • 84872020321 scopus 로고    scopus 로고
    • Cell-to-cell transmission can overcome multiple donor and target cell barriers imposed on cell-free HIV
    • 10.1371/journal.pone.0053138, 3538641, 23308151
    • Zhong P, Agosto LM, Ilinskaya A, Dorjbal B, Truong R, Derse D, Uchil PD, Heidecker G, Mothes W. Cell-to-cell transmission can overcome multiple donor and target cell barriers imposed on cell-free HIV. PLoS One 2013, 8:e53138. 10.1371/journal.pone.0053138, 3538641, 23308151.
    • (2013) PLoS One , vol.8
    • Zhong, P.1    Agosto, L.M.2    Ilinskaya, A.3    Dorjbal, B.4    Truong, R.5    Derse, D.6    Uchil, P.D.7    Heidecker, G.8    Mothes, W.9
  • 42
    • 79955114733 scopus 로고    scopus 로고
    • Tetherin does not significantly restrict dendritic cell-mediated HIV-1 transmission and its expression is upregulated by newly synthesized HIV-1 Nef
    • 10.1186/1742-4690-8-26, 3108291, 21504576
    • Coleman CM, Spearman P, Wu L. Tetherin does not significantly restrict dendritic cell-mediated HIV-1 transmission and its expression is upregulated by newly synthesized HIV-1 Nef. Retrovirology 2011, 8:26. 10.1186/1742-4690-8-26, 3108291, 21504576.
    • (2011) Retrovirology , vol.8 , pp. 26
    • Coleman, C.M.1    Spearman, P.2    Wu, L.3
  • 43
    • 84869194198 scopus 로고    scopus 로고
    • Innate sensing of HIV-1 assembly by tetherin induces NFkappaB-dependent proinflammatory responses
    • 10.1016/j.chom.2012.10.007, 3556742, 23159053
    • Galao RP, Le Tortorec A, Pickering S, Kueck T, Neil SJ. Innate sensing of HIV-1 assembly by tetherin induces NFkappaB-dependent proinflammatory responses. Cell Host Microbe 2012, 12:633-644. 10.1016/j.chom.2012.10.007, 3556742, 23159053.
    • (2012) Cell Host Microbe , vol.12 , pp. 633-644
    • Galao, R.P.1    Le Tortorec, A.2    Pickering, S.3    Kueck, T.4    Neil, S.J.5
  • 44
    • 33947627531 scopus 로고    scopus 로고
    • Mechanisms of CD4 downregulation by the Nef and Vpu proteins of primate immunodeficiency viruses
    • 10.2174/156652407780059177, 17346169
    • Lindwasser OW, Chaudhuri R, Bonifacino JS. Mechanisms of CD4 downregulation by the Nef and Vpu proteins of primate immunodeficiency viruses. Curr Mol Med 2007, 7:171-184. 10.2174/156652407780059177, 17346169.
    • (2007) Curr Mol Med , vol.7 , pp. 171-184
    • Lindwasser, O.W.1    Chaudhuri, R.2    Bonifacino, J.S.3
  • 47
    • 84861324358 scopus 로고    scopus 로고
    • Virus-activated interferon regulatory factor 7 upregulates expression of the interferon-regulated BST2 gene independently of interferon signaling
    • 10.1128/JVI.06971-11, 3302510, 22301143
    • Bego MG, Mercier J, Cohen EA. Virus-activated interferon regulatory factor 7 upregulates expression of the interferon-regulated BST2 gene independently of interferon signaling. J Virol 2012, 86:3513-3527. 10.1128/JVI.06971-11, 3302510, 22301143.
    • (2012) J Virol , vol.86 , pp. 3513-3527
    • Bego, M.G.1    Mercier, J.2    Cohen, E.A.3
  • 48
    • 0033151621 scopus 로고    scopus 로고
    • The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells
    • 10.1016/S1074-7613(00)80065-5, 10403641
    • Cohen GB, Gandhi RT, Davis DM, Mandelboim O, Chen BK, Strominger JL, Baltimore D. The selective downregulation of class I major histocompatibility complex proteins by HIV-1 protects HIV-infected cells from NK cells. Immunity 1999, 10:661-671. 10.1016/S1074-7613(00)80065-5, 10403641.
    • (1999) Immunity , vol.10 , pp. 661-671
    • Cohen, G.B.1    Gandhi, R.T.2    Davis, D.M.3    Mandelboim, O.4    Chen, B.K.5    Strominger, J.L.6    Baltimore, D.7
  • 49
    • 0032489864 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Vpr is a positive regulator of viral transcription and infectivity in primary human macrophages
    • 10.1084/jem.187.7.1103, 2212198, 9529326
    • Subbramanian RA, Kessous-Elbaz A, Lodge R, Forget J, Yao XJ, Bergeron D, Cohen EA. Human immunodeficiency virus type 1 Vpr is a positive regulator of viral transcription and infectivity in primary human macrophages. J Exp Med 1998, 187:1103-1111. 10.1084/jem.187.7.1103, 2212198, 9529326.
    • (1998) J Exp Med , vol.187 , pp. 1103-1111
    • Subbramanian, R.A.1    Kessous-Elbaz, A.2    Lodge, R.3    Forget, J.4    Yao, X.J.5    Bergeron, D.6    Cohen, E.A.7
  • 50
    • 0025139857 scopus 로고
    • The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release
    • 249152, 2404139
    • Klimkait T, Strebel K, Hoggan MD, Martin MA, Orenstein JM. The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release. J Virol 1990, 64:621-629. 249152, 2404139.
    • (1990) J Virol , vol.64 , pp. 621-629
    • Klimkait, T.1    Strebel, K.2    Hoggan, M.D.3    Martin, M.A.4    Orenstein, J.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.