HIV-1 Vpu protein antagonizes innate restriction factor BST-2 via lipid-embedded helix-helix interactions

Journal of Biological Chemistry

Volumn 287, Issue 1, 2012, Pages 58-67

  Skasko, Mark ^a   Wang, Yan ^b   Tian, Ye ^b   Tokarev, Andrey ^a   Munguia, Jason ^a   Ruiz, Autumn ^c   Stephens, Edward B ^c   Opella, Stanley J ^b   Guatelli, Ohn ^a,d  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^d VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROAD SPECTRUM; C-TERMINAL REGIONS; HELIX-HELIX INTERACTIONS; HELIX-HELIX PACKING; HELIX-HELIX PAIRING; HYDROPHOBIC RESIDUES; INNATE IMMUNE RESPONSE; INNATE IMMUNITY; INTERMOLECULAR INTERACTIONS; KEY FEATURE; NON-HUMAN PRIMATE; ORTHOLOGS; TILT ANGLE; TRANS-MEMBRANE DOMAINS; VIRAL INFECTIONS;

ACTIVATION ANALYSIS; AMINO ACIDS; LIPID BILAYERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEINS;

DISEASES;

ALANINE; LIPID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BST 2; TRYPTOPHAN; UNCLASSIFIED DRUG; VPU PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE MAPPING; HOST PATHOGEN INTERACTION; HOST RESISTANCE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INNATE IMMUNITY; LIPID BILAYER; MOLECULAR DOCKING; MOLECULAR INTERACTION; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANTIGENS, CD; CELL MEMBRANE; GPI-LINKED PROTEINS; HELA CELLS; HIV-1; HUMAN IMMUNODEFICIENCY VIRUS PROTEINS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMMUNITY, INNATE; LIPID BILAYERS; MICELLES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; THERMODYNAMICS; VIRAL REGULATORY AND ACCESSORY PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS 1; PRIMATES;

EID: 84855272482     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.296772     Document Type: Article

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