3-D neurohistology of transparent tongue in health and injury with optical clearing

Frontiers in Neuroanatomy

Volumn 7, Issue OCT, 2013, Pages

  Hua, Tzu En ^a   Yang, Tsung Lin ^b,c   Yang, Wen Chan ^d   Liu, Ko Jiunn ^d,e   Tang, Shiue Cheng ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Neural network; Neurohistology; Neuromuscular junction; Optical clearing; Papilla; Skeletal muscle; Tongue innervation; Tongue lesion

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR SYSTEM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INNERVATION; MOUSE; MUCOSA; NERVE CELL; NERVE CELL NETWORK; NEUROMUSCULAR SYNAPSE; NONHUMAN; OPTICAL CLEARING; PHOTON; TASTE BUD; THREE DIMENSIONAL IMAGING; TISSUE INJURY; TONGUE; TONGUE INJURY;

EID: 84887034149     PISSN: 16625129     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnana.2013.00036     Document Type: Article

References (43)

1. Aps, J. K., and Martens, L. C. (2005). Review: the physiology of saliva and transfer of drugs into saliva. Forensic Sci. Int. 150, 119-131. doi: 10.1016/j.forsciint.2004.10.026.
2. Arvidsson, U., Riedl, M., Elde, R., and Meister, B. (1997). Vesicular acetylcholine transporter (VAChT) protein: a novel and unique marker for cholinergic neurons in the central and peripheral nervous systems. J. Comp. Neurol. 378, 454-467. doi: 10.1002/(SICI)1096-9861(19970224)378:4<454::AIDCNE2>3.0.CO;2-1.
3. Batbayar, B., Zelles, T., Ver, A., and Feher, E. (2004). Plasticity of the different neuropeptide-containing nerve fibres in the tongue of the diabetic rat. J. Peripher. Nerv. Syst. 9, 215-223. doi: 10.1111/j.1085-9489.2004.09402.x.
4. Berlanga, M. L., Phan, S., Bushong, E. A., Wu, S., Kwon, O., Phung, B. S., et al. (2011). Three-dimensional reconstruction of serial mouse brain sections: solution for flattening high-resolution large-scale mosaics. Front. Neuroanat. 5:17. doi: 10.3389/fnana.2011.00017.
5. Carl Zeiss Microimaging GmbH. (2009). Visualizing the Architecture of Cells and Tissues. Brochures for Laser Scanning Microscopy. Available online at:http://microscopy.zeiss.com/microscopy/en_gb/downloads/brochure-downloads.html?catalog=biowhitepaper. [Accessed 06 August 2013].
6. Chiu, Y. C., Hua, T. E., Fu, Y. Y., Pasricha, P. J., and Tang, S. C. (2012). 3-D imaging and illustration of the perfusive mouse islet sympathetic innervation and its remodelling in injury. Diabetologia 55, 3252-3261. doi: 10.1007/s00125-012-2699-6.
7. Demir, I. E., Friess, H., and Ceyhan, G. O. (2012). Nerve-cancer interactions in the stromal biology of pancreatic cancer. Front. Physiol. 3:97. doi: 10.3389/fphys.2012.00097.
8. Dios, P. D., and Leston, J. S. (2010). Oral cancer pain. Oral Oncol. 46, 448-451. doi: 10.1016/j.oraloncology.2010.02.017.
9. El-Rouby, D. H. (2011). Histological and immunohistochemical evaluation of the chemopreventive role of lycopene in tongue carcinogenesis induced by 4-nitroquinoline-1-oxide. Arch. Oral Biol. 56, 664-671. doi: 10.1016/j.archoralbio.2010.12.007.
10. Fu, Y. Y., Lin, C. W., Enikolopov, G., Sibley, E., Chiang, A. S., and Tang, S. C. (2009). Microtome-free 3-dimensional confocal imaging method for visualization of mouse intestine with subcellular-level resolution. Gastroenterology 137, 453-465. doi: 10.1053/j.gastro.2009.05.008.
11. Fu, Y. Y., Lu, C. H., Lin, C. W., Juang, J. H., Enikolopov, G., Sibley, E., et al. (2010). Three-dimensional optical method for integrated visualization of mouse islet microstructure and vascular network with subcellular-level resolution. J. Biomed. Opt. 15, 046018. doi: 10.1117/1.3470241.
12. Fu, Y. Y., Peng, S. J., Lin, H. Y., Pasricha, P. J., and Tang, S. C. (2013). 3-D imaging and illustration of mouse intestinal neurovascular complex. Am. J. Physiol. Gastrointest. Liver Physiol. 304, G1-G11. doi: 10.1152/ajpgi.00209.2012.
13. Fu, Y. Y., and Tang, S. C. (2010). At the movies: 3-dimensional technology and gastrointestinal histology. Gastroenterology 139, 1100-1105. doi: 10.1053/j.gastro.2010.08.025.
14. Hiiemae, K. M., and Palmer, J. B. (2003). Tongue movements in feeding and speech. Crit. Rev. Oral Biol. Med. 14, 413-429. doi: 10.1177/154411130301400604.
15. Kanojia, D., and Vaidya, M. M. (2006). 4-nitroquinoline-1-oxide induced experimental oral carcinogenesis. Oral Oncol. 42, 655-667. doi: 10.1016/j.oraloncology.2005.10.013.
16. Kolokythas, A., Cox, D. P., Dekker, N., and Schmidt, B. L. (2010). Nerve growth factor and tyrosine kinase A receptor in oral squamous cell carcinoma: is there an association with perineural invasion. J. Oral Maxillofac. Surg. 68, 1290-1295. doi: 10.1016/j.joms.2010.01.006.
17. Krishnan, M. M., Venkatraghavan, V., Acharya, U. R., Pal, M., Paul, R. R., Min, L. C., et al. (2012). Automated oral cancer identification using histopathological images: a hybrid feature extraction paradigm. Micron 43, 352-364. doi: 10.1016/j.micron.2011.09.016.
18. Kusakabe, T., Matsuda, H., Gono, Y., Furukawa, M., Hiruma, H., Kawakami, T., et al. (1998). Immunohistochemical localisation of regulatory neuropeptides in human circumvallate papillae. J. Anat. 192(Pt 4), 557-564. doi: 10.1046/j.1469-7580.1998.19240557.x.
19. Liu, Y. A., Chen, Y., Chiang, A. S., Peng, S. J., Pasricha, P. J., and Tang, S. C. (2011). Optical clearing improves the imaging depth and signal-to-noise ratio for digital analysis and three-dimensional projection of the human enteric nervous system. Neurogastroenterol. Motil. 23, e446-e457. doi: 10.1111/j.1365-2982.2011.01773.x.
20. Liu, Y. A., Chung, Y. C., Pan, S. T., Hou, Y. C., Peng, S. J., Pasricha, P. J., et al. (2012). 3-D illustration of network orientations of interstitial cells of Cajal subgroups in human colon as revealed by deep-tissue imaging with optical clearing. Am. J. Physiol. Gastrointest. Liver Physiol. 302, G1099-G1110. doi: 10.1152/ajpgi.00432.2011.
21. Liu, Y. A., Chung, Y. C., Pan, S. T., Shen, M. Y., Hou, Y. C., Peng, S. J., et al. (2013). 3-D imaging, illustration, and quantitation of enteric glial network in transparent human colon mucosa. Neurogastroenterol. Motil. 25, e324-e338. doi: 10.1111/nmo.12115.
22. Maeda, M., Ohba, N., Nakagomi, S., Suzuki, Y., Kiryu-Seo, S., Namikawa, K., et al. (2004). Vesicular acetylcholine transporter can be a morphological marker for the reinnervation to muscle of regenerating motor axons. Neurosci. Res. 48, 305-314. doi: 10.1016/j.neures.2003.11.008.
23. Miller, A. J. (2008). The neurobiology of swallowing and dysphagia. Dev. Disabil. Res. Rev. 14, 77-86. doi: 10.1002/ddrr.12.
24. Mu, L., and Sanders, I. (2010). Human tongue neuroanatomy: nerve supply and motor endplates. Clin. Anat. 23, 777-791. doi: 10.1002/ca.21011.
25. Nosrat, C. A. (1998). Neurotrophic factors in the tongue: expression patterns, biological activity, relation to innervation and studies of neurotrophin knockout mice. Ann. N.Y. Acad. Sci. 855, 28-49. doi: 10.1111/j.1749-6632.1998.tb10544.x.
26. Nosrat, I. V., Margolskee, R. F., and Nosrat, C. A. (2012). Targeted taste cell-specific overexpression of brain-derived neurotrophic factor in adult taste buds elevates phosphorylated TrkB protein levels in taste cells, increases taste bud size, and promotes gustatory innervation. J. Biol. Chem. 287, 16791-16800. doi: 10.1074/jbc.M111.328476.
27. Ondicova, K., and Mravec, B. (2010). Role of nervous system in cancer aetiopathogenesis. Lancet Oncol. 11, 596-601. doi: 10.1016/S1470-2045(09)70337-7.
28. Raju, B., Haug, S. R., Ibrahim, S. O., and Heyeraas, K. J. (2007). Sympathectomy decreases size and invasiveness of tongue cancer in rats. Neuroscience 149, 715-725. doi: 10.1016/j.neuroscience.2007.07.048.
29. Raju, B., and Ibrahim, S. O. (2011). Pathophysiology of oral cancer in experimental animal models: a review with focus on the role of sympathetic nerves. J. Oral Pathol. Med. 40, 1-9. doi: 10.1111/j.1600-0714.2010.00928.x.
30. Sbarbati, A., Merigo, F., Bernardi, P., Crescimanno, C., Benati, D., and Osculati, F. (2002). Ganglion cells and topographically related nerves in the vallate papilla/von Ebner gland complex. J. Histochem. Cytochem. 50, 709-718. doi: 10.1177/002215540205000512.
31. Schuller, H. M., and Al-Wadei, H. A. (2010). Neurotransmitter receptors as central regulators of pancreatic cancer. Future Oncol. 6, 221-228. doi: 10.2217/fon.09.171.
32. Smith, K. (2011). Neurogastroenterology: improving 3D imaging of the enteric nervous system. Nat. Rev. Gastroenterol. Hepatol. 8, 600. doi: 10.1038/nrgastro.2011.167.
33. Tang, S. C., Chiu, Y. C., Hsu, C. T., Peng, S. J., and Fu, Y. Y. (2013). Plasticity of Schwann cells and pericytes in response to islet injury in mice. Diabetologia 56, 2424-2434. doi: 10.1007/s00125-013-2977-y.
34. Tatsuta, M., Iishi, H., Baba, M., and Taniguchi, H. (1992). Inhibition of azoxymethane-induced experimental colon carcinogenesis in Wistar rats by 6-hydroxydopamine. Int. J. Cancer 50, 298-301. doi: 10.1002/ijc.2910500221.
35. Tseng, S. J., Lee, Y. H., Chen, Z. H., Lin, H. H., Lin, C. Y., and Tang, S. C. (2009). Integration of optical clearing and optical sectioning microscopy for three-dimensional imaging of natural biomaterial scaffolds in thin sections. J. Biomed. Opt. 14, 044004. doi: 10.1117/1.3158998.
36. Tuchin, V. V., Wang, R. K., and Yeh, A. T. (2008). Optical clearing of tissues and cells.J. Biomed. Opt. 13, 021101. doi: 10.1117/1.2903745.
37. Vered, M., Yarom, N., and Dayan, D. (2005). 4NQO oral carcinogenesis: animal models, molecular markers and future expectations. Oral Oncol. 41, 337-339. doi: 10.1016/j.oraloncology.2004.07.005.
38. Viet, C. T., and Schmidt, B. L. (2012). Biologic mechanisms of oral cancer pain and implications for clinical therapy. J. Dent. Res. 91, 447-453. doi: 10.1177/0022034511424156.
39. Wakisaka, S., Miyawaki, Y., Youn, S. H., Kato, J., and Kurisu, K. (1996). Protein gene-product 9.5 in developing mouse circumvallate papilla: comparison with neuron-specific enolase and calcitonin gene-related peptide. Anat. Embryol. (Berl) 194, 365-372. doi: 10.1007/BF00198538.
40. Witt, M., and Reutter, K. (1998). Innervation of developing human taste buds. An immunohistochemical study. Histochem. Cell Biol. 109, 281-291. doi: 10.1007/s004180050228.
41. Ye, Y., Dang, D., Zhang, J., Viet, C. T., Lam, D. K., Dolan, J. C., et al. (2011). Nerve growth factor links oral cancer progression, pain, and cachexia. Mol. Cancer Ther. 10, 1667-1676. doi: 10.1158/1535-7163.MCT-11-0123.
42. Zelles, T., Purushotham, K. R., Macauley, S. P., Oxford, G. E., and Humphreys-Beher, M. G. (1995). Saliva and growth factors: the fountain of youth resides in us all. J. Dent. Res. 74, 1826-1832. doi: 10.1177/00220345950740120301.
43. Zhang, Z. W., Burke, M. W., Calakos, N., Beaulieu, J. M., and Vaucher, E. (2010). Confocal analysis of cholinergic and dopaminergic inputs onto pyramidal cells in the prefrontal cortex of rodents. Front. Neuroanat. 4:21. doi: 10.3389/fnana.2010.00021.