메뉴 건너뛰기




Volumn 58, Issue 5, 2013, Pages 1713-1723

Protein kinase a-dependent pSer675-β-catenin, a novel signaling defect in a mouse model of congenital hepatic fibrosis

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTEIN CDC42; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UVOMORULIN;

EID: 84887019729     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26554     Document Type: Article
Times cited : (46)

References (39)
  • 1
    • 79958081521 scopus 로고    scopus 로고
    • Polycystic liver diseases: congenital disorders of cholangiocyte signaling
    • 1859 e1851.
    • Strazzabosco M, Somlo S. Polycystic liver diseases: congenital disorders of cholangiocyte signaling. Gastroenterology 2011;140:1855-1859, 1859 e1851.
    • (2011) Gastroenterology , vol.140 , pp. 1855-1859
    • Strazzabosco, M.1    Somlo, S.2
  • 2
    • 0036509712 scopus 로고    scopus 로고
    • The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein
    • Ward CJ, Hogan MC, Rossetti S, Walker D, Sneddon T, Wang X, et al. The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein. Nat Genet 2002;30:259-269.
    • (2002) Nat Genet , vol.30 , pp. 259-269
    • Ward, C.J.1    Hogan, M.C.2    Rossetti, S.3    Walker, D.4    Sneddon, T.5    Wang, X.6
  • 3
    • 67649841563 scopus 로고    scopus 로고
    • Autosomal dominant polycystic kidney disease: the last 3 years
    • Torres VE, Harris PC. Autosomal dominant polycystic kidney disease: the last 3 years. Kidney Int 2009;76:149-168.
    • (2009) Kidney Int , vol.76 , pp. 149-168
    • Torres, V.E.1    Harris, P.C.2
  • 4
    • 44949107444 scopus 로고    scopus 로고
    • Mechanoregulation of intracellular Ca2+ in human autosomal recessive polycystic kidney disease cyst-lining renal epithelial cells
    • Rohatgi R, Battini L, Kim P, Israeli S, Wilson PD, Gusella GL, et al. Mechanoregulation of intracellular Ca2+ in human autosomal recessive polycystic kidney disease cyst-lining renal epithelial cells. Am J Physiol Renal Physiol 2008;294:F890-899.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Rohatgi, R.1    Battini, L.2    Kim, P.3    Israeli, S.4    Wilson, P.D.5    Gusella, G.L.6
  • 5
    • 58949089448 scopus 로고    scopus 로고
    • The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD)
    • Banales JM, Masyuk TV, Gradilone SA, Masyuk AI, Medina JF, LaRusso NF. The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD). Hepatology 2009;49:160-174.
    • (2009) Hepatology , vol.49 , pp. 160-174
    • Banales, J.M.1    Masyuk, T.V.2    Gradilone, S.A.3    Masyuk, A.I.4    Medina, J.F.5    LaRusso, N.F.6
  • 7
    • 33947315462 scopus 로고    scopus 로고
    • Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine 3',5'-cyclic monophosphate
    • Masyuk TV, Masyuk AI, Torres VE, Harris PC, Larusso NF. Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine 3', 5'-cyclic monophosphate. Gastroenterology 2007;132:1104-1116.
    • (2007) Gastroenterology , vol.132 , pp. 1104-1116
    • Masyuk, T.V.1    Masyuk, A.I.2    Torres, V.E.3    Harris, P.C.4    Larusso, N.F.5
  • 8
    • 26444486391 scopus 로고    scopus 로고
    • Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination
    • Hino S, Tanji C, Nakayama KI, Kikuchi A. Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination. Mol Cell Biol 2005;25:9063-9072.
    • (2005) Mol Cell Biol , vol.25 , pp. 9063-9072
    • Hino, S.1    Tanji, C.2    Nakayama, K.I.3    Kikuchi, A.4
  • 9
    • 33744519452 scopus 로고    scopus 로고
    • Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase
    • Taurin S, Sandbo N, Qin Y, Browning D, Dulin NO. Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase. J Biol Chem 2006;281:9971-9976.
    • (2006) J Biol Chem , vol.281 , pp. 9971-9976
    • Taurin, S.1    Sandbo, N.2    Qin, Y.3    Browning, D.4    Dulin, N.O.5
  • 10
    • 48249109979 scopus 로고    scopus 로고
    • Phosphorylation of beta-catenin by PKA promotes ATP-induced proliferation of vascular smooth muscle cells
    • Taurin S, Sandbo N, Yau DM, Sethakorn N, Dulin NO. Phosphorylation of beta-catenin by PKA promotes ATP-induced proliferation of vascular smooth muscle cells. Am J Physiol Cell Physiol 2008;294:C1169-1174.
    • (2008) Am J Physiol Cell Physiol , vol.294
    • Taurin, S.1    Sandbo, N.2    Yau, D.M.3    Sethakorn, N.4    Dulin, N.O.5
  • 11
    • 84870252814 scopus 로고    scopus 로고
    • The complex world of WNT receptor signalling
    • Niehrs C. The complex world of WNT receptor signalling. Nat Rev Mol Cell Biol;13:767-779.
    • Nat Rev Mol Cell Biol , vol.13 , pp. 767-779
    • Niehrs, C.1
  • 12
    • 84865302520 scopus 로고    scopus 로고
    • Activation of canonical WNT/beta-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition
    • Kahlert UD, Maciaczyk D, Doostkam S, Orr BA, Simons B, Bogiel T, et al. Activation of canonical WNT/beta-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to-mesenchymal transition. Cancer Lett 2012;325:42-53.
    • (2012) Cancer Lett , vol.325 , pp. 42-53
    • Kahlert, U.D.1    Maciaczyk, D.2    Doostkam, S.3    Orr, B.A.4    Simons, B.5    Bogiel, T.6
  • 13
    • 80052271808 scopus 로고    scopus 로고
    • Apico-basal polarity in polycystic kidney disease epithelia
    • Wilson PD. Apico-basal polarity in polycystic kidney disease epithelia. Biochim Biophys Acta 2011;1812:1239-1248.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 1239-1248
    • Wilson, P.D.1
  • 14
    • 84864290534 scopus 로고    scopus 로고
    • E-cadherin plays an essential role in collective directional migration of large epithelial sheets
    • Li L, Hartley R, Reiss B, Sun Y, Pu J, Wu D, et al. E-cadherin plays an essential role in collective directional migration of large epithelial sheets. Cell Mol Life Sci 2012;69:2779-2789.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 2779-2789
    • Li, L.1    Hartley, R.2    Reiss, B.3    Sun, Y.4    Pu, J.5    Wu, D.6
  • 17
    • 84857364721 scopus 로고    scopus 로고
    • A Rac1/PAK1 cascade controls beta-catenin activation in colon cancer cells
    • Zhu G, Wang Y, Huang B, Liang J, Ding Y, Xu A, et al. A Rac1/PAK1 cascade controls beta-catenin activation in colon cancer cells. Oncogene 2012;31:1001-1012.
    • (2012) Oncogene , vol.31 , pp. 1001-1012
    • Zhu, G.1    Wang, Y.2    Huang, B.3    Liang, J.4    Ding, Y.5    Xu, A.6
  • 18
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-catenin, and cadherin pathways
    • Nelson WJ, Nusse R. Convergence of Wnt, beta-catenin, and cadherin pathways. Science 2004;303:1483-1487.
    • (2004) Science , vol.303 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 19
    • 84870528219 scopus 로고    scopus 로고
    • Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib
    • Spirli C, Morell CM, Locatelli L, Okolicsanyi S, Ferrero C, Kim AK, et al. Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib. Hepatology 2012;56:2363-2374.
    • (2012) Hepatology , vol.56 , pp. 2363-2374
    • Spirli, C.1    Morell, C.M.2    Locatelli, L.3    Okolicsanyi, S.4    Ferrero, C.5    Kim, A.K.6
  • 20
    • 84857399769 scopus 로고    scopus 로고
    • Altered store operated calcium entry increases cyclic 3',5'-adenosine monophosphate production and extracellular signal-regulated kinases 1 and 2 phosphorylation in polycystin-2-defective cholangiocytes
    • Spirli C, Locatelli L, Fiorotto R, Morell CM, Fabris L, Pozzan T, et al. Altered store operated calcium entry increases cyclic 3', 5'-adenosine monophosphate production and extracellular signal-regulated kinases 1 and 2 phosphorylation in polycystin-2-defective cholangiocytes. Hepatology 2012;55:856-868.
    • (2012) Hepatology , vol.55 , pp. 856-868
    • Spirli, C.1    Locatelli, L.2    Fiorotto, R.3    Morell, C.M.4    Fabris, L.5    Pozzan, T.6
  • 21
    • 77951429069 scopus 로고    scopus 로고
    • Mammalian target of rapamycin regulates vascular endothelial growth factor-dependent liver cyst growth in polycystin-2-defective mice
    • Spirli C, Okolicsanyi S, Fiorotto R, Fabris L, Cadamuro M, Lecchi S, et al. Mammalian target of rapamycin regulates vascular endothelial growth factor-dependent liver cyst growth in polycystin-2-defective mice. Hepatology 2010;51:1778-1788.
    • (2010) Hepatology , vol.51 , pp. 1778-1788
    • Spirli, C.1    Okolicsanyi, S.2    Fiorotto, R.3    Fabris, L.4    Cadamuro, M.5    Lecchi, S.6
  • 22
    • 72249123155 scopus 로고    scopus 로고
    • ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice
    • Spirli C, Okolicsanyi S, Fiorotto R, Fabris L, Cadamuro M, Lecchi S, et al. ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice. Gastroenterology 2010;138:360-371 e367.
    • (2010) Gastroenterology , vol.138
    • Spirli, C.1    Okolicsanyi, S.2    Fiorotto, R.3    Fabris, L.4    Cadamuro, M.5    Lecchi, S.6
  • 24
    • 53349173236 scopus 로고    scopus 로고
    • Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling
    • Lal M, Song X, Pluznick JL, Di Giovanni V, Merrick DM, Rosenblum ND, et al. Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling. Hum Mol Genet 2008;17:3105-3117.
    • (2008) Hum Mol Genet , vol.17 , pp. 3105-3117
    • Lal, M.1    Song, X.2    Pluznick, J.L.3    Di Giovanni, V.4    Merrick, D.M.5    Rosenblum, N.D.6
  • 25
    • 7244231107 scopus 로고    scopus 로고
    • Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney disease
    • Masyuk TV, Huang BQ, Masyuk AI, Ritman EL, Torres VE, Wang X, et al. Biliary dysgenesis in the PCK rat, an orthologous model of autosomal recessive polycystic kidney disease. Am J Pathol 2004;165:1719-1730.
    • (2004) Am J Pathol , vol.165 , pp. 1719-1730
    • Masyuk, T.V.1    Huang, B.Q.2    Masyuk, A.I.3    Ritman, E.L.4    Torres, V.E.5    Wang, X.6
  • 26
    • 84879174086 scopus 로고    scopus 로고
    • Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice
    • Epub ahead of print].
    • Fiorotto R, Raizner A, Morell CM, Torsello B, Scirpo R, Fabris L, et al. Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice. J Hepatol 2013 [Epub ahead of print].
    • (2013) J Hepatol
    • Fiorotto, R.1    Raizner, A.2    Morell, C.M.3    Torsello, B.4    Scirpo, R.5    Fabris, L.6
  • 27
    • 80053580862 scopus 로고    scopus 로고
    • Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-kappaB-mediated inflammatory response in mice
    • 1508 e1491-1495.
    • Fiorotto R, Scirpo R, Trauner M, Fabris L, Hoque R, Spirli C, et al. Loss of CFTR affects biliary epithelium innate immunity and causes TLR4-NF-kappaB-mediated inflammatory response in mice. Gastroenterology 2011;141:1498-1508, 1508 e1491-1495.
    • (2011) Gastroenterology , vol.141 , pp. 1498-1508
    • Fiorotto, R.1    Scirpo, R.2    Trauner, M.3    Fabris, L.4    Hoque, R.5    Spirli, C.6
  • 28
    • 68549106083 scopus 로고    scopus 로고
    • E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer
    • Schmalhofer O, Brabletz S, Brabletz T. E-cadherin, beta-catenin, and ZEB1 in malignant progression of cancer. Cancer Metastasis Rev 2009;28:151-166.
    • (2009) Cancer Metastasis Rev , vol.28 , pp. 151-166
    • Schmalhofer, O.1    Brabletz, S.2    Brabletz, T.3
  • 29
    • 77956064817 scopus 로고    scopus 로고
    • Cell adhesion: integrating cytoskeletal dynamics and cellular tension
    • Parsons JT, Horwitz AR, Schwartz MA. Cell adhesion: integrating cytoskeletal dynamics and cellular tension. Nat Rev Mol Cell Biol 2010;11:633-643.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 633-643
    • Parsons, J.T.1    Horwitz, A.R.2    Schwartz, M.A.3
  • 30
    • 67249091839 scopus 로고    scopus 로고
    • Polycystic kidney disease
    • Harris PC, Torres VE. Polycystic kidney disease. Annu Rev Med 2009;60:321-337.
    • (2009) Annu Rev Med , vol.60 , pp. 321-337
    • Harris, P.C.1    Torres, V.E.2
  • 31
    • 67649884993 scopus 로고    scopus 로고
    • Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways
    • Happe H, Leonhard WN, van der Wal A, van de Water B, Lantinga-van Leeuwen IS, Breuning MH, et al. Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways. Hum Mol Genet 2009;18:2532-2542.
    • (2009) Hum Mol Genet , vol.18 , pp. 2532-2542
    • Happe, H.1    Leonhard, W.N.2    van der Wal, A.3    van de Water, B.4    Lantinga-van Leeuwen, I.S.5    Breuning, M.H.6
  • 32
    • 79959785834 scopus 로고    scopus 로고
    • T-cell factor/beta-catenin activity is suppressed in two different models of autosomal dominant polycystic kidney disease
    • Miller MM, Iglesias DM, Zhang Z, Corsini R, Chu L, Murawski I, et al. T-cell factor/beta-catenin activity is suppressed in two different models of autosomal dominant polycystic kidney disease. Kidney Int 2011;80:146-153.
    • (2011) Kidney Int , vol.80 , pp. 146-153
    • Miller, M.M.1    Iglesias, D.M.2    Zhang, Z.3    Corsini, R.4    Chu, L.5    Murawski, I.6
  • 33
    • 84864856934 scopus 로고    scopus 로고
    • c-Met and NF-kappaB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease
    • Qin S, Taglienti M, Cai L, Zhou J, Kreidberg JA. c-Met and NF-kappaB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease. J Am Soc Nephrol 2012;23:1309-1318.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1309-1318
    • Qin, S.1    Taglienti, M.2    Cai, L.3    Zhou, J.4    Kreidberg, J.A.5
  • 34
    • 79959811780 scopus 로고    scopus 로고
    • WNT/beta-catenin signaling in polycystic kidney disease
    • Wuebken A, Schmidt-Ott KM. WNT/beta-catenin signaling in polycystic kidney disease. Kidney Int 2011;80:135-138.
    • (2011) Kidney Int , vol.80 , pp. 135-138
    • Wuebken, A.1    Schmidt-Ott, K.M.2
  • 35
    • 84866179288 scopus 로고    scopus 로고
    • The Akt1 isoform is required for optimal IFN-beta transcription through direct phosphorylation of beta-catenin
    • Gantner BN, Jin H, Qian F, Hay N, He B, Ye RD. The Akt1 isoform is required for optimal IFN-beta transcription through direct phosphorylation of beta-catenin. J Immunol;189:3104-3111.
    • J Immunol , vol.189 , pp. 3104-3111
    • Gantner, B.N.1    Jin, H.2    Qian, F.3    Hay, N.4    He, B.5    Ye, R.D.6
  • 36
    • 77951881189 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) cross-talks with canonical Wnt signaling via phosphorylation of beta-catenin at Ser 552
    • Zhao J, Yue W, Zhu MJ, Sreejayan N, Du M. AMP-activated protein kinase (AMPK) cross-talks with canonical Wnt signaling via phosphorylation of beta-catenin at Ser 552. Biochem Biophys Res Commun;395:146-151.
    • Biochem Biophys Res Commun , vol.395 , pp. 146-151
    • Zhao, J.1    Yue, W.2    Zhu, M.J.3    Sreejayan, N.4    Du, M.5
  • 37
    • 84868711769 scopus 로고    scopus 로고
    • Fellow travellers: emergent properties of collective cell migration
    • Rorth P. Fellow travellers: emergent properties of collective cell migration. EMBO Rep 2012;13:984-991.
    • (2012) EMBO Rep , vol.13 , pp. 984-991
    • Rorth, P.1
  • 38
    • 63049085679 scopus 로고    scopus 로고
    • A Rac GTPase-activating protein, MgcRacGAP, is a nuclear localizing signal-containing nuclear chaperone in the activation of STAT transcription factors
    • Kawashima T, Bao YC, Minoshima Y, Nomura Y, Hatori T, Hori T, et al. A Rac GTPase-activating protein, MgcRacGAP, is a nuclear localizing signal-containing nuclear chaperone in the activation of STAT transcription factors. Mol Cell Biol 2009;29:1796-1813.
    • (2009) Mol Cell Biol , vol.29 , pp. 1796-1813
    • Kawashima, T.1    Bao, Y.C.2    Minoshima, Y.3    Nomura, Y.4    Hatori, T.5    Hori, T.6
  • 39
    • 84876716657 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling and small molecule inhibitors
    • Voronkov A, Krauss S. Wnt/beta-catenin signaling and small molecule inhibitors. Curr Pharm Des 2013;19:634-664.
    • (2013) Curr Pharm Des , vol.19 , pp. 634-664
    • Voronkov, A.1    Krauss, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.