RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy

Human Molecular Genetics

Volumn 22, Issue 22, 2013, Pages 4474-4484

  Ihara, Ryoko ^a   Matsukawa, Koji ^a   Nagata, Yusei ^a   Kunugi, Hayato ^a   Tsuji, Shoji ^a   Chihara, Takahiro ^a   Kuranaga, Erina ^a   Miura, Masayuki ^a   Wakabayashi, Tomoko ^a   Hashimoto, Tadafumi ^a   Iwatsubo, Takeshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; TAR DNA BINDING PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DROSOPHILA MELANOGASTER; FEMALE; FRUIT FLY MODEL; GENE EXPRESSION; GENE MUTATION; GENE OVEREXPRESSION; LABORATORY; MALE; MOLECULAR RECOGNITION; NERVE CELL; NERVE CELL DEGENERATION; NEUROTOXICITY; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE MOTIF; PHENOTYPE; PHOTORECEPTOR CELL; PRIORITY JOURNAL; RNA BINDING; TDP 43 PROTEINOPATHY; TRANSGENIC ANIMAL; VISUAL SYSTEM PARAMETERS; WILD TYPE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BINDING SITES; CYTOSOL; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; HUMANS; NERVE DEGENERATION; PHENOTYPE; PHOTORECEPTOR CELLS, INVERTEBRATE; RETINAL DEGENERATION; RNA; RNA-BINDING PROTEINS; TDP-43 PROTEINOPATHIES;

EID: 84887011964     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt296     Document Type: Article

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