-
1
-
-
79956310563
-
Structural analysis of the mechanism of inhibition and allosteric activation of the kinase domain of HER2 protein
-
Aertgeerts, K., Skene, R., Yano, J., Sang, B. C., Zou, H., Snell, G., ? Sogabe, S. (2011). Structural analysis of the mechanism of inhibition and allosteric activation of the kinase domain of HER2 protein. The Journal of Biological Chemistry, 286, 18756-18765.
-
(2011)
The Journal of Biological Chemistry
, vol.286
, pp. 18756-18765
-
-
Aertgeerts, K.1
Skene, R.2
Yano, J.3
Sang, B.C.4
Zou, H.5
Snell, G.6
Sogabe, S.7
-
2
-
-
84986512474
-
CHARMM: A program for macromolecular energy minimization and dynamics calculations
-
Brooks, B. R., Bruccoleri, R. E., Olafson, B. D., States, D. J., Swaminathan, S., & Karplus, M. (1983). CHARMM: A program for macromolecular energy minimization and dynamics calculations. Journal of Computational Chemistry, 4, 187-217.
-
(1983)
Journal of Computational Chemistry
, vol.4
, pp. 187-217
-
-
Brooks, B.R.1
Bruccoleri, R.E.2
Olafson, B.D.3
States, D.J.4
Swaminathan, S.5
Karplus, M.6
-
3
-
-
84855282742
-
Two birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicine
-
Chang, S. S., Huang, H. J., & Chen, C. Y. C. (2011). Two birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicine. PLoS Computational Biology, 7, e1002315.
-
(2011)
PLoS Computational Biology
, vol.7
-
-
Chang, S.S.1
Huang, H.J.2
Chen, C.Y.C.3
-
4
-
-
79959444251
-
ISMART: An integrated cloud computing web server for traditional Chinese medicine for online virtual screening, de novo evolution and drug design
-
Chang, K. W., Tsai, T. Y., Chen, K. C., Yang, S. C., Huang, H. J., Chang, T. T., ? Chen, C. Y. C. (2011). ISMART: An integrated cloud computing web server for traditional Chinese medicine for online virtual screening, de novo evolution and drug design. Journal of Biomolecular Structure & Dynamics, 29, 243-250.
-
(2011)
Journal of Biomolecular Structure & Dynamics
, vol.29
, pp. 243-250
-
-
Chang, K.W.1
Tsai, T.Y.2
Chen, K.C.3
Yang, S.C.4
Huang, H.J.5
Chang, T.T.6
Chen, Y.C.7
-
6
-
-
77249097809
-
Bioinformatics, chemoinformatics, and pharmainformatics analysis of HER2/HSP90 dual-targeted inhibitors
-
Chen, C. Y. C. (2010). Bioinformatics, chemoinformatics, and pharmainformatics analysis of HER2/HSP90 dual-targeted inhibitors. Journal of the Taiwan Institute of Chemical Engineers, 41, 143-149.
-
(2010)
Journal of the Taiwan Institute of Chemical Engineers
, vol.41
, pp. 143-149
-
-
Chen, C.Y.C.1
-
7
-
-
79251561193
-
TCM database@Taiwan: The world's largest traditional Chinese medicine database for drug screening in silico
-
Chen, C. Y. C. (2011). TCM database@Taiwan: The world?s largest traditional Chinese medicine database for drug screening in silico. PLoS ONE, 6, e15939.
-
(2011)
PLoS ONE
, vol.6
-
-
Chen, C.Y.C.1
-
8
-
-
84866065800
-
In silico identification of potent pancreatic triacylglycerol lipase inhibitors from traditional Chinese medicine
-
Chen, K. Y., Chang, S. S., & Chen, C. Y. C. (2012). In silico identification of potent pancreatic triacylglycerol lipase inhibitors from traditional Chinese medicine. PLoS ONE, 7, e43932.
-
(2012)
PLoS ONE
, vol.7
-
-
Chen, K.Y.1
Chang, S.S.2
Chen, C.Y.C.3
-
9
-
-
77955772552
-
Insights into designing the dual-targeted HER2/HSP90 inhibitors
-
Chen, C. Y., & Chen, C. Y. C. (2010). Insights into designing the dual-targeted HER2/HSP90 inhibitors. Journal of Molecular Graphics & Modelling, 29, 21-31.
-
(2010)
Journal of Molecular Graphics & Modelling
, vol.29
, pp. 21-31
-
-
Chen, C.Y.1
Chen, C.Y.C.2
-
10
-
-
79953746295
-
Stroke prevention by traditional Chinese medicine? A genetic algorithm, support vector machine and molecular dynamics approach
-
Chen, K. C., & Chen, C. Y. C. (2011). Stroke prevention by traditional Chinese medicine? A genetic algorithm, support vector machine and molecular dynamics approach. Soft Matter, 7, 4001-4008.
-
(2011)
Soft Matter
, vol.7
, pp. 4001-4008
-
-
Chen, K.C.1
Chen, C.Y.C.2
-
11
-
-
44149095494
-
Molecular simulation of HER2/neu degradation by inhibiting HSP90
-
Chen, C. Y. C., Chen, G. W., & Chen, W. Y. C. (2008). Molecular simulation of HER2/neu degradation by inhibiting HSP90. Journal of the Chinese Chemical Society, 55, 297-302.
-
(2008)
Journal of the Chinese Chemical Society
, vol.55
, pp. 297-302
-
-
Chen, C.Y.C.1
Chen, G.W.2
Chen, W.Y.C.3
-
12
-
-
80052619174
-
Investigation into potent inflammation inhibitors from traditional Chinese medicine
-
Chen, K. C., Sun, M. F., Yang, S. C., Chang, S. S., Chen, H. Y., Tsai, F. J., & Chen, C. Y. C. (2011). Investigation into potent inflammation inhibitors from traditional Chinese medicine. Chemical Biology & Drug Design, 78, 679-688.
-
(2011)
Chemical Biology & Drug Design
, vol.78
, pp. 679-688
-
-
Chen, K.C.1
Sun, M.F.2
Yang, S.C.3
Chang, S.S.4
Chen, H.Y.5
Tsai, F.J.6
Chen, C.Y.C.7
-
13
-
-
84859842130
-
Treatment options for patients with recurrent or metastatic squamous cell carcinoma of the head and neck, who progress after platinum-based chemotherapy
-
de Andrade, D. A. P., & Machiels, J. P. (2012). Treatment options for patients with recurrent or metastatic squamous cell carcinoma of the head and neck, who progress after platinum-based chemotherapy. Current Opinion in Oncology, 24, 211-217.
-
(2012)
Current Opinion in Oncology
, vol.24
, pp. 211-217
-
-
De Andrade, D.A.P.1
Machiels, J.P.2
-
14
-
-
0004280908
-
-
New York, NY: Academic Press
-
Fletcher, R. (1969). Optimization. New York, NY: Academic Press.
-
(1969)
Optimization
-
-
Fletcher, R.1
-
15
-
-
2342492317
-
Review of epidermal growth factor receptor biology
-
DOI 10.1016/j.ijrobp.2003.11.041, PII S0360301604003311
-
Herbst R. S. (2004). Review of epidermal growth factor receptor biology. International Journal of Radiation Oncology Biology Physics, 59, 21-26. (Pubitemid 38610223)
-
(2004)
International Journal of Radiation Oncology Biology Physics
, vol.59
, Issue.2 SUPPL.
, pp. 21-26
-
-
Herbst, R.S.1
-
16
-
-
46249092554
-
GROMACS 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation
-
Hess, B., Kutzner, C., van der Spoel, D., & Lindahl, E. (2008). GROMACS 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation. Journal of Chemical Theory and Computation, 4, 435-447.
-
(2008)
Journal of Chemical Theory and Computation
, vol.4
, pp. 435-447
-
-
Hess, B.1
Kutzner, C.2
Van Der Spoel, D.3
Lindahl, E.4
-
17
-
-
84862825103
-
Lu-177-DO3A-HSA-Z (EGFR:1907): Characterization as a potential radiopharmaceutical for radionuclide therapy of EGFR-expressing head and neck carcinomas
-
Hoppmann, S., Qi, S. B., Miao, Z., Liu, H. G., Jiang, H., Cutler, C. S., ? Cheng, Z. (2012). Lu-177-DO3A-HSA-Z (EGFR:1907): Characterization as a potential radiopharmaceutical for radionuclide therapy of EGFR-expressing head and neck carcinomas. Journal of Biological Inorganic Chemistry, 17, 709-718.
-
(2012)
Journal of Biological Inorganic Chemistry
, vol.17
, pp. 709-718
-
-
Hoppmann, S.1
Qi, S.B.2
Miao, Z.3
Liu, H.G.4
Jiang, H.5
Cutler, C.S.6
Cheng, Z.7
-
18
-
-
77956546672
-
Structure-based and ligand-based drug design for HER 2 receptor
-
Huang, H. J., Lee, K. J., Yu, H. W., Chen, C. Y., Hsu, C. H., Chen, H. Y., & Tsai, F. J. (2010). Structure-based and ligand-based drug design for HER 2 receptor. Journal of Biomolecular Structure & Dynamics, 28, 23-37.
-
(2010)
Journal of Biomolecular Structure & Dynamics
, vol.28
, pp. 23-37
-
-
Huang, H.J.1
Lee, K.J.2
Yu, H.W.3
Chen, C.Y.4
Hsu, C.H.5
Chen, H.Y.6
Tsai, F.J.7
-
19
-
-
79956148112
-
Uroporphyrinogen decarboxylase: Optimizing radiotherapy for head and neck cancer
-
Ito, E., Yip, K. W., & Liu, F. F. (2011). Uroporphyrinogen decarboxylase: Optimizing radiotherapy for head and neck cancer. Future Oncology, 7, 595-597.
-
(2011)
Future Oncology
, vol.7
, pp. 595-597
-
-
Ito, E.1
Yip, K.W.2
Liu, F.F.3
-
20
-
-
79251504609
-
Uroporphyrinogen decarboxylase is a radiosensitizing target for head and neck cancer
-
Ito, E., Yue, S., Moriyama, E. H., Hui, A. B., Kim, I., Shi, W., ? Liu, F. F. (2011). Uroporphyrinogen decarboxylase is a radiosensitizing target for head and neck cancer. Science Translational Medicine, 3, 67ra7.
-
(2011)
Science Translational Medicine
, vol.3
-
-
Ito, E.1
Yue, S.2
Moriyama, E.H.3
Hui, A.B.4
Kim, I.5
Shi, W.6
Liu, F.F.7
-
21
-
-
79952232216
-
Global cancer statistics
-
Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., & Forman, D. (2011). Global cancer statistics. Cancer Journal for Clinicians, 61, 69-90.
-
(2011)
Cancer Journal for Clinicians
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
22
-
-
84861777141
-
Combined molecular targeted drug therapy for EGFR and HER-2 in head and neck squamous cell carcinoma cell lines
-
Kondo, N., Tsukuda, M., Sakakibara, A., Takahashi, H.,, H., Komatsu, M., ? Toth, G. (2012). Combined molecular targeted drug therapy for EGFR and HER-2 in head and neck squamous cell carcinoma cell lines. International Journal of Oncology, 40, 1805-1812.
-
(2012)
International Journal of Oncology
, vol.40
, pp. 1805-1812
-
-
Kondo, N.1
Tsukuda, M.2
Sakakibara, A.3
Takahashi, H.H.4
Komatsu, M.5
Toth, G.6
-
23
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
DOI 10.1016/S0169-409X(00)00129-0, PII S0169409X00001290
-
Lipinski, C. A., Lombardo, F., Dominy, B. W., & Feeney, P. J. (2001). Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Advanced Drug Delivery Reviews, 46, 3-26. (Pubitemid 33653411)
-
(2000)
Advanced Drug Delivery Reviews
, vol.46
, Issue.1-3
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
24
-
-
84861189997
-
Cancer stem cells hypothesis and stem cells in head and neck cancers
-
Mannelli, G., & Gallo, O. (2012). Cancer stem cells hypothesis and stem cells in head and neck cancers. Cancer Treatment Reviews, 38, 515-539.
-
(2012)
Cancer Treatment Reviews
, vol.38
, pp. 515-539
-
-
Mannelli, G.1
Gallo, O.2
-
25
-
-
84862075775
-
Radiotherapy for head and neck cancer: An increasing dependence on innovative imaging
-
Nuyts, S., & Fairchild, A. (2012). Radiotherapy for head and neck cancer: An increasing dependence on innovative imaging. Onkologie, 35, 287-292.
-
(2012)
Onkologie
, vol.35
, pp. 287-292
-
-
Nuyts, S.1
Fairchild, A.2
-
26
-
-
0347504852
-
Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase
-
DOI 10.1093/emboj/cdg606
-
Phillips, J. D., Whitby, F. G., Kushner, J. P., & Hill, C. P. (2003). Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase. The EMBO Journal, 22, 6225-6233. (Pubitemid 37522580)
-
(2003)
EMBO Journal
, vol.22
, Issue.23
, pp. 6225-6233
-
-
Phillips, J.D.1
Whitby, F.G.2
Kushner, J.P.3
Hill, C.P.4
-
27
-
-
33846199078
-
Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP
-
Phillips, J. D., Whitby, F. G., Stadtmueller, B. M., Edwards, C. Q., Hill, C. P., & Kushner, J. P. (2007). Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP). Translational Research, 149, 85-91.
-
(2007)
Translational Research
, vol.149
, pp. 85-91
-
-
Phillips, J.D.1
Whitby, F.G.2
Stadtmueller, B.M.3
Edwards, C.Q.4
Hill, C.P.5
Kushner, J.P.6
-
28
-
-
84857246429
-
Head and neck tumors
-
In R. Pazdur L. D. Wagman, K. A. Camphausen, & W. J. Hoskins (Eds. Retrieved from
-
Ridge, J. A., Glisson, B. S., Lango, M. N., & Feigenberg, S. (2011). Head and neck tumors. In R. Pazdur, L. D. Wagman, K. A. Camphausen, & W. J. Hoskins (Eds.), Cancer management: A multidisciplinary approach. Retrieved from http://www.cancernetwork.com/cancer-management/head-and-neck/article/10165/ 1802498
-
(2011)
Cancer Management: A Multidisciplinary Approach
-
-
Ridge, J.A.1
Glisson, B.S.2
Lango, M.N.3
Feigenberg, S.4
-
29
-
-
80052340860
-
Screening from TCM Database@Taiwan and QSAR model for identifying HER2 inhibitors
-
Sun, M. F., Yang, S. C., Chang, K. W., Tsai, T. Y., Chen, H. Y., Tsai, F. J., ? Chen, C. Y. C. (2011). Screening from TCM Database@Taiwan and QSAR model for identifying HER2 inhibitors. Molecular Simulation, 37, 884-892.
-
(2011)
Molecular Simulation
, vol.37
, pp. 884-892
-
-
Sun, M.F.1
Yang, S.C.2
Chang, K.W.3
Tsai, T.Y.4
Chen, H.Y.5
Tsai, F.J.6
Chen, C.Y.C.7
-
30
-
-
33749242759
-
Contribution of conformer focusing to the uncertainty in predicting free energies for protein-ligand binding
-
DOI 10.1021/jm060763i
-
Tirado-Rives, J., & Jorgensen, W. L. (2006). Contribution of conformer focusing to the uncertainty in predicting free energies for protein-ligand binding. Journal of Medicinal Chemistry, 49, 5880-5884. (Pubitemid 44484934)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.20
, pp. 5880-5884
-
-
Tirado-Rives, J.1
Jorgensen, W.L.2
-
31
-
-
84863362562
-
In silico investigation of potential SRC kinase ligands from traditional Chinese medicine
-
Tou, W. I., & Chen, C. Y. (2012). In silico investigation of potential SRC kinase ligands from traditional Chinese medicine. PLoS ONE, 7, e33728.
-
(2012)
PLoS ONE
, vol.7
-
-
Tou, W.I.1
Chen, C.Y.2
-
32
-
-
80051545693
-
IScreen: World's first cloud-computing web server for virtual screening and de novo drug design based on TCM database@Taiwan
-
Tsai, T. Y., Chang, K. W., & Chen, C. Y. C. (2011). IScreen: World's first cloud-computing web server for virtual screening and de novo drug design based on TCM database@Taiwan. Journal of Computer-Aided Molecular Design, 25, 525-531.
-
(2011)
Journal of Computer-Aided Molecular Design
, vol.25
, pp. 525-531
-
-
Tsai, T.Y.1
Chang, K.W.2
Chen, C.Y.C.3
-
33
-
-
84859323557
-
A novel algorithm for identification of activated cryptic 5 splice sites
-
Tsai, K. N., Chen, G. W., & Chen, C. Y. C. (2012). A novel algorithm for identification of activated cryptic 5? splice sites. Journal of Biomolecular Structure & Dynamics, 29, 1089-1099.
-
(2012)
Journal of Biomolecular Structure & Dynamics
, vol.29
, pp. 1089-1099
-
-
Tsai, K.N.1
Chen, G.W.2
Chen, C.Y.C.3
-
34
-
-
0037212102
-
LigandFit: A novel method for the shape-directed rapid docking of ligands to protein active sites
-
DOI 10.1016/S1093-3263(02)00164-X, PII S109332630200164X
-
Venkatachalam, C. M., Jiang, X., Oldfield, T., & Waldman, M. (2003). LigandFit: A novel method for the shape-directed rapid docking of ligands to protein active sites. Journal of Molecular Graphics and Modelling, 21, 289-307. (Pubitemid 35441326)
-
(2003)
Journal of Molecular Graphics and Modelling
, vol.21
, Issue.4
, pp. 289-307
-
-
Venkatachalam, C.M.1
Jiang, X.2
Oldfield, T.3
Waldman, M.4
-
35
-
-
0027921638
-
Head and neck cancer
-
Vokes, E. E., Weichselbaum, R. R., Lippman, S. M., & Hong, W. K. (1993). Head and neck cancer. The New England Journal of Medicine, 328, 184-194.
-
(1993)
The New England Journal of Medicine
, vol.328
, pp. 184-194
-
-
Vokes, E.E.1
Weichselbaum, R.R.2
Lippman, S.M.3
Hong, W.K.4
-
36
-
-
0028922586
-
LIGPLOT: A program to generate schematic diagrams of protein-ligand interactions
-
Wallace, A. C., Laskowski, R. A., & Thornton, J. M. (1995). LIGPLOT: A program to generate schematic diagrams of protein-ligand interactions. Protein Engineering, 8, 127-134.
-
(1995)
Protein Engineering
, vol.8
, pp. 127-134
-
-
Wallace, A.C.1
Laskowski, R.A.2
Thornton, J.M.3
-
37
-
-
83155183294
-
Identifying HER2 inhibitors from natural products database
-
Yang, S. C., Chang, S. S., & Chen, C. Y. C. (2011). Identifying HER2 inhibitors from natural products database. PLoS ONE, 6, e28793.
-
(2011)
PLoS ONE
, vol.6
-
-
Yang, S.C.1
Chang, S.S.2
Chen, C.Y.C.3
-
38
-
-
80055077153
-
Identification of potent EGFR inhibitors from TCM database@ Taiwan
-
Yang, S. C., Chang, S. S., Chen, H. Y., & Chen, C. Y. C. (2011). Identification of potent EGFR inhibitors from TCM database@ Taiwan. PLoS Computational Biology, 7, e1002189.
-
(2011)
PLoS Computational Biology
, vol.7
-
-
Yang, S.C.1
Chang, S.S.2
Chen, H.Y.3
Chen, C.Y.C.4
-
39
-
-
84862586383
-
A dual-targeting antibody against EGFR-VEGF for lung and head and neck cancer treatment
-
Zhang, H., Yun, S., Batuwangala, T. D., Steward, M., Holmes, S. D., Pan, L.,? Shin, D. M. (2012). A dual-targeting antibody against EGFR-VEGF for lung and head and neck cancer treatment. International Journal of Cancer, 131, 956-969.
-
(2012)
International Journal of Cancer
, vol.131
, pp. 956-969
-
-
Zhang, H.1
Yun, S.2
Batuwangala, T.D.3
Steward, M.4
Holmes, S.D.5
Pan, L.6
Shin, D.M.7
-
40
-
-
79958841703
-
SwissParam: A fast force field generation tool for small organic molecules
-
Zoete, V., Cuendet, M. A., Grosdidier, A., & Michielin, O. (2011). SwissParam: A fast force field generation tool for small organic molecules. Journal of Computational Chemistry, 32, 2359-2368.
-
(2011)
Journal of Computational Chemistry
, vol.32
, pp. 2359-2368
-
-
Zoete, V.1
Cuendet, M.A.2
Grosdidier, A.3
Michielin, O.4
-
41
-
-
84865344990
-
A new role of PET/CT for target delineation for radiotherapy treatment planning for head and neck carcinomas
-
Zygogianni, A., Kyrgias, G., Kouvaris, J., Pistevou-Gompaki, K., & Kouloulias, V. (2012). A new role of PET/CT for target delineation for radiotherapy treatment planning for head and neck carcinomas. Hellenic Journal of Nuclear Medicine, 15, 139-143.
-
(2012)
Hellenic Journal of Nuclear Medicine
, vol.15
, pp. 139-143
-
-
Zygogianni, A.1
Kyrgias, G.2
Kouvaris, J.3
Pistevou-Gompaki, K.4
Kouloulias, V.5
|