Hepatitis C and pregnancy

World Journal of Gastroenterology

Volumn 19, Issue 40, 2013, Pages 6714-6720

  Floreani, Annarosa ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Hepatitis C virus; Liver damage; Pregnancy; Viral RNA; Virus transmission

Indexed keywords

ALANINE AMINOTRANSFERASE; PEGINTERFERON; RIBAVIRIN; VIRUS RNA;

ARTICLE; BLOOD TRANSFUSION; CESAREAN SECTION; DISEASE EXACERBATION; FEMALE; FETUS OUTCOME; HEPATITIS C; HUMAN; LOW BIRTH WEIGHT; MENTAL DISEASE; MIXED INFECTION; PREGNANCY; PREMATURE LABOR; RISK FACTOR; SPONTANEOUS ABORTION; TERATOGENICITY; VERTICAL TRANSMISSION; VIRAL CLEARANCE; VIRUS LOAD;

HEPATITIS C VIRUS; LIVER DAMAGE; PREGNANCY; VIRAL RNA; VIRUS TRANSMISSION;

ACUTE DISEASE; ANTIVIRAL AGENTS; BIOLOGICAL MARKERS; COINFECTION; DISEASE PROGRESSION; DRUG THERAPY, COMBINATION; FEMALE; HEPACIVIRUS; HEPATITIS C; HEPATITIS C, CHRONIC; HIV INFECTIONS; HUMANS; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; RISK FACTORS; RNA, VIRAL; TREATMENT OUTCOME; VIRAL LOAD;

EID: 84887001114     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v19.i40.6714     Document Type: Article

References (78)

1. Baldo V, Baldovin T, Trivello R, Floreani A. Epidemiology of HCV infection. Curr Pharm Des 2008; 14: 1646-1654 [PMID: 18673187]
2. Le Campion A, Larouche A, Fauteux-Daniel S, Soudeyns H. Pathogenesis of hepatitis C during pregnancy and childhood. Viruses 2012; 4: 3531-3550 [PMID: 23223189 DOI: 10.3390/v4123531]
3. Hillemanns P, Dannecker C, Kimmig R, Hasbargen U. Obstetric risks and vertical transmission of hepatitis C virus infection in pregnancy. Acta Obstet Gynecol Scand 2000; 79: 543-547 [PMID: 10929952]
4. Conte D, Fraquelli M, Prati D, Colucci A, Minola E. Prevalence and clinical course of chronic hepatitis C virus (HCV) infection and rate of HCV vertical transmission in a cohort of 15,250 pregnant women. Hepatology 2000; 31: 751-755 [PMID: 10706568]
5. Ward C, Tudor-Williams G, Cotzias T, Hargreaves S, Regan L, Foster GR. Prevalence of hepatitis C among pregnant women attending an inner London obstetric department: uptake and acceptability of named antenatal testing. Gut 2000; 47: 277-280 [PMID: 10896922]
6. Baldo V, Floreani A, Menegon T, Grella P, Paternoster DM, Trivello R. Hepatitis C virus, hepatitis B virus and human immunodeficiency virus infection in pregnant women in North-East Italy: a seroepidemiological study. Eur J Epidemiol 2000; 16: 87-91 [PMID: 10780348]
7. Goldberg D, McIntyre PG, Smith R, Appleyard K, Dunlop J, Taylor A, Hutchinson S. Hepatitis C virus among high and low risk pregnant women in Dundee: unlinked anonymous testing. BJOG 2001; 108: 365-370 [PMID: 11305542]
8. Kumar A, Sharma KA, Gupta RK, Kar P, Chakravarti A. Prevalence & risk factors for hepatitis C virus among pregnant women. Indian J Med Res 2007; 126: 211-215 [PMID: 18037715]
9. Sami S, Korejo R, Bhutta SZ. Prevalence of hepatitis B and C: a Jinnah Postgraduate Medical Centre experience. J Obstet Gynaecol Res 2009; 35: 533-538 [PMID: 19527395 DOI: 10.1111/j.1447-0756.2008.00991.x]
10. Ohto H, Ishii T, Kitazawa J, Sugiyama S, Ujiie N, Fujimori K, Ariga H, Satoh T, Nollet KE, Okamoto H, Hoshi T. Declining hepatitis C virus (HCV) prevalence in pregnant women: impact of anti-HCV screening of donated blood. Transfusion 2010; 50: 693-700 [PMID: 19912584 DOI: 10.1111/ j.1537-2995.2009.02487.x]
11. Seisdedos T, Díaz A, Bleda MJ, Ortiz M, García A, Díez M. Prevalence of maternal hepatitis C infection according to HIV serostatus in six Spanish regions (2003-2006). Eur J Public Health 2011; 21: 643-645 [PMID: 20639521 DOI: 10.1093/ eurpub/ckq085]
12. Ugbebor O, Aigbirior M, Osazuwa F, Enabudoso E, Zabayo O. The prevalence of hepatitis B and C viral infections among pregnant women. N Am J Med Sci 2011; 3: 238-241 [PMID: 22558601 DOI: 10.4297/najms.2011.3238]
13. Pinto CS, Martins RM, Andrade SM, Stief AC, Oliveira RD, Castro AR. Hepatitis C virus infection among pregnant women in Central-Western Brazil, 2005-2007. Rev Saude Publica 2011; 45: 974-976 [PMID: 21829975]
14. Urbanus AT, van de Laar TJ, van den Hoek A, Zuure FR, Speksnijder AG, Baaten GG, Heijman T, Vriend HJ, Op de Coul EL, Coutinho RA, Prins M. Hepatitis C in the general population of various ethnic origins living in the Netherlands: should non-Western migrants be screened? J Hepatol 2011; 55: 1207-1214 [PMID: 21703202 DOI: 10.1016/ j.jhep.2011.02.028]
15. Stoszek SK, Abdel-Hamid M, Narooz S, El Daly M, Saleh DA, Mikhail N, Kassem E, Hawash Y, El Kafrawy S, Said A, El Batanony M, Shebl FM, Sayed M, Sharaf S, Fix AD, Strickland GT. Prevalence of and risk factors for hepatitis C in rural pregnant Egyptian women. Trans R Soc Trop Med Hyg 2006; 100: 102-107 [PMID: 16289168]
16. Paccagnini S, Principi N, Massironi E, Tanzi E, Romanò L, Muggiasca ML, Ragni MC, Salvaggio L. Perinatal transmission and manifestation of hepatitis C virus infection in a high risk population. Pediatr Infect Dis J 1995; 14: 195-199 [PMID: 7761184]
17. Zanetti AR, Tanzi E, Paccagnini S, Principi N, Pizzocolo G, Caccamo ML, D'Amico E, Cambiè G, Vecchi L. Mother-toinfant transmission of hepatitis C virus. Lombardy Study Group on Vertical HCV Transmission. Lancet 1995; 345: 289-291 [PMID: 7530793]
18. Granovsky MO, Minkoff HL, Tess BH, Waters D, Hatzakis A, Devoid DE, Landesman SH, Rubinstein A, Di Bisceglie AM, Goedert JJ. Hepatitis C virus infection in the mothers and infants cohort study. Pediatrics 1998; 102: 355-359 [PMID: 9685438]
19. Hillemanns P, Langenegger P, Langer BC, Knitza R, Hasbargen U, Hepp H. [Prevalence and follow-up of hepatitis C virus infection in pregnancy]. Z Geburtshilfe Neonatol 1998; 202: 127-130 [PMID: 9715529]
20. Resti M, Azzari C, Mannelli F, Moriondo M, Novembre E, de Martino M, Vierucci A. Mother to child transmission of hepatitis C virus: prospective study of risk factors and timing of infection in children born to women seronegative for HIV-1. Tuscany Study Group on Hepatitis C Virus Infection. BMJ 1998; 317: 437-441 [PMID: 9703524]
21. Gervais A, Bacq Y, Bernuau J, Martinot M, Auperin A, Boyer N, Kilani A, Erlinger S, Valla D, Marcellin P. Decrease in serum ALT and increase in serum HCV RNA during pregnancy in women with chronic hepatitis C. J Hepatol 2000; 32: 293-299 [PMID: 10707870]
22. Mast EE, Hwang LY, Seto DS, Nolte FS, Nainan OV, Wurtzel H, Alter MJ. Risk factors for perinatal transmission of hepatitis C virus (HCV) and the natural history of HCV infection acquired in infancy. J Infect Dis 2005; 192: 1880-1889 [PMID: 16267758]
23. Zahran KM, Badary MS, Agban MN, Abdel Aziz NH. Pattern of hepatitis virus infection among pregnant women and their newborns at the Women's Health Center of Assiut University, Upper Egypt. Int J Gynaecol Obstet 2010; 111: 171-174 [PMID: 20708181 DOI: 10.1016/j.ijgo.2010.06.013]
24. Flichman D, Cello J, Castaño G, Campos R, Sookoian S. In vivo down regulation of HIV replication after hepatitis C superinfection. Medicina (B Aires) 1999; 59: 364-366 [PMID: 10752201]
25. Ozaslan E, Yilmaz R, Simsek H, Tatar G. Interferon therapy for acute hepatitis C during pregnancy. Ann Pharmacother 2002; 36: 1715-1718 [PMID: 12398565]
26. Gonzalez F, Medam-Djomo MA, Lucidarme D, Khalil A, Decoster A, Houze de L'Aulnoit D, Filoche B. Acute hepatitis C during the third trimester of pregnancy. Gastroenterol Clin Biol 2006; 30: 786-789 [PMID: 16801905]
27. Kogure T, Ueno Y, Kanno N, Fukushima K, Yamagiwa Y, Nagasaki F, Kakazu E, Matsuda Y, Kido O, Nakagome Y, Ninomiya M, Shimosegawa T. Sustained viral response of a case of acute hepatitis C virus infection via needle-stick injury. World J Gastroenterol 2006; 12: 4757-4760 [PMID: 16937453]
28. Sookoian S. Liver disease during pregnancy: acute viral hepatitis. Ann Hepatol 2006; 5: 231-236 [PMID: 17060891]
29. Khuroo MS, Kamili S. Aetiology, clinical course and outcome of sporadic acute viral hepatitis in pregnancy. J Viral Hepat 2003; 10: 61-69 [PMID: 12558914]
30. Hsieh TY, Yu CH, Kuo PL, Chang FM. Acute viral hepatitis C-induced jaundice in pregnancy. Taiwan J Obstet Gynecol 2006; 45: 180-182 [PMID: 17197365]
31. Zhang RL, Zeng JS, Zhang HZ. Survey of 34 pregnant women with hepatitis A and their neonates. Chin Med J (Engl) 1990; 103: 552-555 [PMID: 1698588]
32. Gomes-Gouvêa MS, Pereira Soares Mdo C, Guedes de Carvalho Mello IM, Brito EM, Pereira Moia de J, Bensabath G, Nunes HM, Carrilho FJ, Pinho JR. Hepatitis D and B virus genotypes in chronically infected patients from the Eastern Amazon Basin. Acta Trop 2008; 106: 149-155 [PMID: 18420172 DOI: 10.1016/j.actatropica.2008.02.009]
33. Khuroo MS, Khuroo MS. Hepatitis E virus. Curr Opin Infect Dis 2008; 21: 539-543 [PMID: 18725805 DOI: 10.1097/ QCO.0b013e32830ee08a]
34. Doshi S, Zucker SD. Liver emergencies during pregnancy. Gastroenterol Clin North Am 2003; 32: 1213-127, ix [PMID: 14696304]
35. Kar P, Jilani N, Husain SA, Pasha ST, Anand R, Rai A, Das BC. Does hepatitis E viral load and genotypes influence the final outcome of acute liver failure during pregnancy? Am J Gastroenterol 2008; 103: 2495-2501 [PMID: 18785952 DOI: 10.1111/j.1572-0241.2008.02032.x]
36. Meng XJ. Recent advances in Hepatitis E virus. J Viral Hepat 2010; 17: 153-161 [PMID: 20040046 DOI: 10.1111/ j.1365-2893.2009.01257.x]
37. Riely CA. Liver disease in the pregnant patient. American College of Gastroenterology. Am J Gastroenterol 1999; 94: 1728-1732 [PMID: 10406228]
38. Guntupalli SR, Steingrub J. Hepatic disease and pregnancy: an overview of diagnosis and management. Crit Care Med 2005; 33: S332-S339 [PMID: 16215356]
39. Baxter JK, Weinstein L. HELLP syndrome: the state of the art. Obstet Gynecol Surv 2004; 59: 838-845 [PMID: 15572962]
40. Riely CA, Bacq Y. Intrahepatic cholestasis of pregnancy. Clin Liver Dis 2004; 8: 167-176 [PMID: 15062199]
41. Hay JE. Liver disease in pregnancy. Hepatology 2008; 47: 1067-1076 [PMID: 18265410 DOI: 10.1002/hep.22130]
42. Ohto H, Terazawa S, Sasaki N, Sasaki N, Hino K, Ishiwata C, Kako M, Ujiie N, Endo C, Matsui A. Transmission of hepatitis C virus from mothers to infants. The Vertical Transmission of Hepatitis C Virus Collaborative Study Group. N Engl J Med 1994; 330: 744-750 [PMID: 8107740]
43. Paternoster DM, Santarossa C, Grella P, Palù G, Baldo V, Boccagni P, Floreani A. Viral load in HCV RNA-positive pregnant women. Am J Gastroenterol 2001; 96: 2751-2754 [PMID: 11569706]
44. Paternoster DM, Belligoli A, Ngaradoumbe NK, Visentin S, Franco R, Fagiuoli S, Boldrin C, Palù G, Baldo V, Floreani A. Endogenous interferon-alpha level is increased in hepatitis C virus (HCV)-positive pregnant women. J Clin Gastroenterol 2008; 42: 204-207 [PMID: 18209593 DOI: 10.1097/01. mcg.0000247991.81591.2e]
45. Pontisso P, Bellati G, Brunetto M, Chemello L, Colloredo G, Di Stefano R, Nicoletti M, Rumi MG, Ruvoletto MG, Soffredini R, Valenza LM, Colucci G. Hepatitis C virus RNA profiles in chronically infected individuals: do they relate to disease activity? Hepatology 1999; 29: 585-589 [PMID: 9918939]
46. Zein CO, Abu-Lebdeh H, Zein NN. Spontaneous clearance of chronic hepatitis C during pregnancy. Am J Gastroenterol 2001; 96: 3044-3045 [PMID: 11693357]
47. Kumar RM, Shahul S. Role of breast-feeding in transmission of hepatitis C virus to infants of HCV-infected mothers. J Hepatol 1998; 29: 191-197 [PMID: 9722199]
48. Fontaine H, Nalpas B, Carnot F, Bréchot C, Pol S. Effect of pregnancy on chronic hepatitis C: a case-control study. Lancet 2000; 356: 1328-1329 [PMID: 11073028]
49. Jabeen T, Cannon B, Hogan J, Crowley M, Devereux C, Fanning L, Kenny-Walsh E, Shanahan F, Whelton MJ. Pregnancy and pregnancy outcome in hepatitis C type 1b. QJM 2000; 93: 597-601 [PMID: 10984554]
50. Floreani A, Paternoster D, Zappala F, Cusinato R, Bombi G, Grella P, Chiaramonte M. Hepatitis C virus infection in pregnancy. Br J Obstet Gynaecol 1996; 103: 325-329 [PMID: 8605128]
51. Pergam SA, Wang CC, Gardella CM, Sandison TG, Phipps WT, Hawes SE. Pregnancy complications associated with hepatitis C: data from a 2003-2005 Washington state birth cohort. Am J Obstet Gynecol 2008; 199: 38. e1-38. e9 [PMID: 18486089 DOI: 10.1016/j.ajog.2008.03.052]
52. Connell LE, Salihu HM, Salemi JL, August EM, Weldeselasse H, Mbah AK. Maternal hepatitis B and hepatitis C carrier status and perinatal outcomes. Liver Int 2011; 31: 1163-1170 [PMID: 21745298 DOI: 10.1111/j.1478-3231.2011.02556.x]
53. Hurtado CW, Golden-Mason L, Brocato M, Krull M, Narkewicz MR, Rosen HR. Innate immune function in placenta and cord blood of hepatitis C-seropositive mother-infant dyads. PLoS One 2010; 5: e12232 [PMID: 20814429 DOI: 10.1371/journal.pone.001223]
54. Berkley EM, Leslie KK, Arora S, Qualls C, Dunkelberg JC. Chronic hepatitis C in pregnancy. Obstet Gynecol 2008; 112: 304-310 [PMID: 18669727 DOI: 10.1097/ AOG.0b013e318180a4f3]
55. Locatelli A, Roncaglia N, Arreghini A, Bellini P, Vergani P, Ghidini A. Hepatitis C virus infection is associated with a higher incidence of cholestasis of pregnancy. Br J Obstet Gynaecol 1999; 106: 498-500 [PMID: 10430202]
56. Paternoster DM, Fabris F, Palù G, Santarossa C, Bracciante R, Snijders D, Floreani A. Intra-hepatic cholestasis of pregnancy in hepatitis C virus infection. Acta Obstet Gynecol Scand 2002; 81: 99-103 [PMID: 11942897]
57. Ropponen A, Sund R, Riikonen S, Ylikorkala O, Aittomäki K. Intrahepatic cholestasis of pregnancy as an indicator of liver and biliary diseases: a population-based study. Hepatology 2006; 43: 723-728 [PMID: 16557542]
58. Marschall HU, Wikström Shemer E, Ludvigsson JF, Stephansson O. Intrahepatic cholestasis of pregnancy and associated hepatobiliary disease: A population-based cohort study. Hepatology 2013; 58: 1385-1391 [PMID: 23564560 DOI: 10.1002/hep.26444]
59. Hinoshita E, Taguchi K, Inokuchi A, Uchiumi T, Kinukawa N, Shimada M, Tsuneyoshi M, Sugimachi K, Kuwano M. Decreased expression of an ATP-binding cassette transporter, MRP2, in human livers with hepatitis C virus infection. J Hepatol 2001; 35: 765-773 [PMID: 11738104]
60. Iwata R, Baur K, Stieger B, Mertens JC, Daly AK, Frei P, Braun J, Vergopoulos A, Stickel F, Sabrane K, Martin IV, Schmitt J, Goetze O, Day CP, Müllhaupt B, Geier A. A common polymorphism in the ABCB11 gene is associated with advanced fibrosis in hepatitis C but not in non-alcoholic fatty liver disease. Clin Sci (Lond) 2011; 120: 287-296 [PMID: 20883210 DOI: 10.1042/CS20100246]
61. Tovo PA, Palomba E, Ferraris G, Principi N, Ruga E, Dallacasa P, Maccabruni A. Increased risk of maternal-infant hepatitis C virus transmission for women coinfected with human immunodeficiency virus type 1. Italian Study Group for HCV Infection in Children. Clin Infect Dis 1997; 25: 1121-1124 [PMID: 9402369]
62. Zanetti AR, Tanzi E, Romanò L, Zuin G, Minola E, Vecchi L, Principi N. A prospective study on mother-to-infant transmission of hepatitis C virus. Intervirology 1998; 41: 208-212 [PMID: 10213898]
63. Gibb DM, Goodall RL, Dunn DT, Healy M, Neave P, Cafferkey M, Butler K. Mother-to-child transmission of hepatitis C virus: evidence for preventable peripartum transmission. Lancet 2000; 356: 904-907 [PMID: 11036896]
64. European Paediatric Hepatitis C Virus Network. Effects of mode of delivery and infant feeding on the risk of mother-tochild transmission of hepatitis C virus. European Paediatric Hepatitis C Virus Network. BJOG 2001; 108: 371-377 [PMID: 11305543]
65. Mariné-Barjoan E, Berrébi A, Giordanengo V, Favre SF, Haas H, Moreigne M, Izopet J, Tricoire J, Tran A, Pradier C, Bongain A. HCV/HIV co-infection, HCV viral load and mode of delivery: risk factors for mother-to-child transmission of hepatitis C virus? AIDS 2007; 21: 1811-1815 [PMID: 17690581]
66. Hayashida A, Inaba N, Oshima K, Nishikawa M, Shoda A, Hayashida S, Negishi M, Inaba F, Inaba M, Fukasawa I, Watanabe H, Takamizawa H. Re-evaluation of the true rate of hepatitis C virus mother-to-child transmission and its novel risk factors based on our two prospective studies. J Obstet Gynaecol Res 2007; 33: 417-422 [PMID: 17688606]
67. Roberts EA, Yeung L. Maternal-infant transmission of hepatitis C virus infection. Hepatology 2002; 36: S106-S113 [PMID: 12407583]
68. Mok J, Pembrey L, Tovo PA, Newell ML. When does mother to child transmission of hepatitis C virus occur? Arch Dis Child Fetal Neonatal Ed 2005; 90: F156-F160 [PMID: 15724041]
69. Indolfi G, Resti M. Perinatal transmission of hepatitis C virus infection. J Med Virol 2009; 81: 836-843 [PMID: 19319981 DOI: 10.1002/jmv.21437]
70. European Paediatric Hepatitis C Virus Network. A significant sex--but not elective cesarean section--effect on motherto-child transmission of hepatitis C virus infection. J Infect Dis 2005; 192: 1872-1879 [PMID: 16267757]
71. Pappalardo BL. Influence of maternal human immunodeficiency virus (HIV) co-infection on vertical transmission of hepatitis C virus (HCV): a meta-analysis. Int J Epidemiol 2003; 32: 727-734 [PMID: 14559740]
72. England K, Thorne C, Newell ML. Vertically acquired paediatric coinfection with HIV and hepatitis C virus. Lancet Infect Dis 2006; 6: 83-90 [PMID: 16439328]
73. Indolfi G, Azzari C, Moriondo M, Lippi F, de Martino M, Resti M. Alanine transaminase levels in the year before pregnancy predict the risk of hepatitis C virus vertical transmission. J Med Virol 2006; 78: 911-914 [PMID: 16721858]
74. Prasad MR, Honegger JR. Hepatitis C virus in pregnancy. Am J Perinatol 2013; 30: 149-159 [PMID: 23389935 DOI: 10.1055/s-0033-1334459]
75. Arshad M, El-Kamary SS, Jhaveri R. Hepatitis C virus infection during pregnancy and the newborn period-are they opportunities for treatment? J Viral Hepat 2011; 18: 229-236 [PMID: 21392169 DOI: 10.1111/j.1365-2893.2010.01413.x]
76. López M, Coll O. Chronic viral infections and invasive procedures: risk of vertical transmission and current recommendations. Fetal Diagn Ther 2010; 28: 1-8 [PMID: 20558971 DOI: 10.1159/000309155]
77. Ghamar Chehreh ME, Tabatabaei SV, Khazanehdari S, Alavian SM. Effect of cesarean section on the risk of perinatal transmission of hepatitis C virus from HCV-RNA+/HIVmothers: a meta-analysis. Arch Gynecol Obstet 2011; 283: 255-260 [PMID: 20652289 DOI: 10.1007/s00404-010-1588-9]
78. Pembrey L, Newell ML, Tovo PA. The management of HCV infected pregnant women and their children European paediatric HCV network. J Hepatol 2005; 43: 515-525 [PMID: 16144064]