A common polymorphism in the ABCB11 gene is associated with advanced fibrosis in hepatitis C but not in non-alcoholic fatty liver disease

Clinical Science

Volumn 120, Issue 7, 2011, Pages 287-296

  Iwata, Rika ^a   Baur, Katharina ^a   Stieger, Bruno ^a,b   Mertens, Joachim C ^a   Daly, Ann K ^c   Frei, Pascal ^a   Braun, Julia ^d   Vergopoulos, Athanasios ^a   Stickel, Felix ^e   Sabrane, Karim ^a   Martin, Ina V ^a,f   Schmitt, Johannes ^a   Goetze, Oliver ^a   Day, Chris P ^c   Müulhaupt, Beat ^a   Geier, Andreas ^a,b  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e UNIVERSITY OF BERN   (Switzerland)

^f UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Bile acid transport; Bile salt export pump (BSEP); Cirrhosis; Farnesoid X receptor (FXR); Non alcoholic fatty liver disease (NAFLD); Single nucleotide polymorphism; Viral hepatitis

Indexed keywords

BILE ACID;

ABCB 11 GENE; ADULT; AGED; ALLELE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; FEMALE; FIBROGENESIS; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HEPATITIS C; HUMAN; LIVER CIRRHOSIS; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; DISEASE PROGRESSION; EPIDEMIOLOGIC METHODS; FATTY LIVER; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEPATITIS C, CHRONIC; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 79951780069     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20100246     Document Type: Article

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