Decrease in serum ALT and increase in serum HCV RNA during pregnancy in women with chronic hepatitis C

Journal of Hepatology

Volumn 32, Issue 2, 2000, Pages 293-299

  Gervais, Anne ^a   Bacq, Yannick ^b   Bernuau, Jacques ^a   Martinot, Michèle ^a   Auperin, Anne ^a   Boyer, Nathalie ^a   Kilani, Afef ^a   Erlinger, Serge ^a   Valla, Dominique ^a   Marcellin, Patrick ^a  

^a INSERM   (France)

^b SERVICE DE DERMATOLOGIE   (France)

Author keywords

Aminotransferases; Chronic hepatitis; HCV RNA; Hepatitis C virus; Pregnancy

Indexed keywords

ALANINE AMINOTRANSFERASE; VIRUS RNA;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CHRONIC HEPATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEPATITIS C; HUMAN; PREGNANCY; PRIORITY JOURNAL; SECOND TRIMESTER PREGNANCY; THIRD TRIMESTER PREGNANCY;

EID: 0033961858     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(00)80075-6     Document Type: Article

References (31)

1. EASL International Consensus Conference on Hepatitis C. J. Hepatol. 30:1999;956-961.
2. Dubois F, Desenclos J-C, Mariotte N, Goudeau A. Hepatitis C in a French population-based survey, 1994: seroprevalence, frequency of viremia, genotype distribution, and risk factors. Hepatology. 25:1997;1490-1496.
3. Roudot-Thoraval F, Pawlotski J-M, Thiers V, Desforges L, Girollet P-P, Guillot F, et al. Lack of mother-to-infant transmission of hepatitis C virus in human immunodefficiency virus-seronegative women: a prospective study with hepatitis C virus RNA testing. Hepatology. 17:1993;772-777.
4. Marcellin P, Bernuau J, Martinot-Peignoux M, Larzul D, Xu LZ, Tran S, et al. Prevalence of hepatitis C virus infection in asymptomatic anti-HIV1 negative pregnant women and their children. Dig Dis Sci. 38:1993;2151-2155.
5. Floreani A, Paternoster D, Zappala F, Cusinato R, Bombi G, Grella P, et al. Hepatitis C virus infection in pregnancy. Br J Obstet Gynaecol. 103:1996;325-329.
6. Reinus J, Leikin E, Alter H, Cheung L, Shindo M, Jett B, et al. Failure to detect vertical transmission of hepatitis C virus. Ann Intern Med. 117:1992;881-886.
7. Manzini P, Saracco G, Cerchier A, Riva C, Musso A, Ricotti E, et al. Human immunodeficiency virus infection as a risk factor for mother-to child hepatitis C virus transmission; persistence of anti-hepatitis C virus in children is associated with the mother's anti-hepatitis C virus immunoblotting pattern. Hepatology. 21:1995;328-332.
8. Wejstal R, Widell A, Mansson A-S, Hermodsson S, Norkrans G. Mother-to-infant transmission of hepatitis C virus. Ann Intern Med. 117:1992;887-890.
9. Ohto H, Terasawa S, Sasak Ni, Sasaki N, Hino K, Ishiwata C, et al. Transmission of Hepatitis C virus from mothers to infants. N Engl J Med. 330:1994;744-750.
10. Lin HH, Kao JH, Hsu HY. Possible role of high titer maternal viremia in perinatal transmission of hepatitis C virus. J Infect Dis. 169:1994;638-641.
11. Zanetti A, Tanzi S, Paccagnini S, Principi N, Pizzocolo G, Caccamo M, et al. Mother to infant transmission of hepatitis C virus. Lancet. 345:1995;289-291.
12. Zuccoti GV, Ribero ML, Giovannini M, Fasola, Riva E, Portera G, et al. Effects of hepatitis C genotype on mother-to-infant transmission of virus. J Pediatr. 127:1995;278-280.
13. Grangé JD, Abergel A, Amiot X, Chaslin-Ferbus D, Aygalenq P, Foukeray B, et al. Interactions entre l'hépatite virale chronique C et la grossesse. Gastroenterol Clin Biol. 19:1995;520-524.
14. Gretch D, Corey L, Wilson, Dela Rosa C, Wilson R, Carithers R, et al. Assessment of hepatitis C virus RNA levels by quantitative competitive RNA polymerase chain reaction: high titer viremia correlates with advanced stage of disease. J Infect Dis. 169:1994;1219-1224.
15. Erickson A, Houghton M, Choo Q, Weiner A, Ralston R, Muchmore E, et al. Hepatitis C virus-specific CTL responses in the liver of chimpanzees with acute and chronic hepatitis C. J Immunol. 151:1993;4189-4199.
16. Botarelli P, Brunetto M, Minutello M, Calvo P, Unutmaz D, Weiner A, et al. T-lymphocyte response to hepatitis C virus in different clinical courses of infection. Gastroenterology. 104:1993;580-587.
17. Ferrari C, Valli A, Galati L, Penna A, Scaccaglia P, Giuberti T, et al. T-cell response to structural and non structural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections. Hepatology. 19:1994;286-295.
18. Mosnier J-F, Degott C, Marcellin P, Hénin D, Erlinger S, Benhamou J-P. The intraportal myphoid nodule and its environment in chronic active hepatitis C: an immunohistochemical study. Hepatology. 17:1993;366-371.
19. Davis G, Lau JY, Urdea MS, Neuwald PD, Wilbert JC, Lindsay K, Perrillo RP. Quantitative detection of hepatitis C virus with a solid-phase amplification method: definition of the optimal conditions for specimen collection and clinical application in interferon-treated patients. Hepatology. 19:1994;1321-1324.
20. Bacq Y, Zarka O, Bréchot J-F, Mariotte N, Vol S, Tichet J, et al. Liver function tests in normal pregnancy: a prospective study of 103 pregnant women and 103 matched controls. Hepatology. 23:1996;1030-1034.
21. Nguyen T, Sedghi-Vaziri A, Wilkes L, Mondala T, Pockros P, Lindsay K, et al. Fluctuations in viral load (HCV RNA) are relatively insignificant in untreated patients with chronic HCV infection. J Viral Hepatol. 3:1996;75-78.
22. Chard T, Craig PH, Menabawey M, Lee C. Alpha Interferon in human pregnancy. Br J Obstet Gynaecol. 93:1986;1145-1149.
23. Weiser B, Nachman S, Tropper P, Viscosi KH, Grimson R, Baxter G, et al. Quantitation of human immunodeficiency virus type 1 during pregnancy: relationship of viral titer to mother-to-child transmission and stability of viral load. Proc Natl Acad Sci USA. 91:1994;8037-8041.
24. Sargent IL. Maternal and fetal immune responses during pregnancy. Exp Clin Immunogenet. 10:1993;85-102.
25. Blackburn ST, Loper DL. Maternal, fetal, and neonatal physiology. A clinical perspective. 1992;Saunders, Philadelphia.
26. Guattery J, Faloon W, Biery D. Effect of ethynil estradiol on chronic active hepatitis. Ann Intern Med. 126:1997;88.
27. Okuyama R, Abo T, Seki S, Ohteki T, Sugiura K, Kusumi A, Kumagai K. Estrogen activates extrathymic T cell differentiation in the liver. J Exp Med. 175:1992;661-669.
28. Kimura M, Hanawa H, Watanabe H, Ogawa M, Abo T. Synchronous expansion of intermediate TCR cells in the liver and uterus during pregnancy. Cell Immunol. 162:1995;16-25.
29. Feinberg BB, Tan NS, Walsh SW, Brath PC, Gonik BL. Progesterone and estradiol suppress human mononuclear cell cytotoxicity. J Reprod Immunol. 21:1992;139-148.
30. Hidaka Y, Amino N, Iwatani Y, Kaneda T, Mitsuda N, Moriloto Y. Changes in natural killer cell activity in normal pregnant and post-partum women: increases in the first and post-partum period and decrease in late pregnancy. J Reprod Immunol. 20:1991;73-83.
31. Salmeron OJ, Vaqer S, Salmeron I, Molto L, Lapena P, Manzano L. Pregnancy is associated with a reduction in the pattern of the cytotoxic activity displayed by lymphokine activated killer cells. Am J Reprod Immunol. 26:1991;150-155.