A novel prophylactic effect of furosemide treatment on autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE)

Epilepsy Research

Volumn 107, Issue 1-2, 2013, Pages 127-137

  Yamada, Junko ^a   Zhu, Gang ^b   Okada, Motohiro ^c   Hirose, Shinichi ^d   Yoshida, Shukuko ^e   Shiba, Yuko ^a   Migita, Keisuke ^a   Mori, Fumiaki ^f   Sugawara, Takayuki ^g   Chen, Lei ^h   Liu, Fang ^b   Yoshida, Shuichi ⁱ   Ueno, Shinya ^a   Kaneko, Sunao ^f  

^a HIROSAKI UNIVERSITY   (Japan)

^b CHINA MEDICAL UNIVERSITY   (China)

^c MIE UNIVERSITY   (Japan)

^d FUKUOKA UNIVERSITY   (Japan)

^e Institute of Neuroscience and Molecular Biology   (Japan)

^f HIROSAKI UNIVERSITY   (Japan)

^g Tohoku Chemical Co Ltd   (Japan)

^h SICHUAN UNIVERSITY   (China)

ⁱ HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ADNFLE; CHRNA4; Furosemide; GABA; KCC2; Prophylactic medication

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; FUROSEMIDE; MESSENGER RNA; POTASSIUM CHLORIDE COTRANSPORTER; POTASSIUM CHLORIDE COTRANSPORTER 1; POTASSIUM CHLORIDE COTRANSPORTER 2; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; UNCLASSIFIED DRUG;

ACTION POTENTIAL; AGE DISTRIBUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; AUTOSOMAL DOMINANT DISORDER; AUTOSOMAL DOMINANT NOCTURNAL FRONTAL LOBE EPILEPSY; BRAIN CORTEX; BRAIN SLICE; CELL POLARITY; CONTROLLED STUDY; DEPOLARIZATION; DISEASE CONTROL; DISEASE COURSE; EPILEPTIC DISCHARGE; EPILEPTOGENESIS; EXCITATORY POSTSYNAPTIC POTENTIAL; FRONTAL CORTEX; FRONTAL LOBE EPILEPSY; GABAERGIC TRANSMISSION; HYPERPOLARIZATION; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; NERVE CELL MEMBRANE POTENTIAL; NEUROPROTECTION; NOCTURNAL SEIZURE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PYRAMIDAL NERVE CELL; RAT; RNA ANALYSIS;

ADNFLE; CHRNA4; FUROSEMIDE; GABA; KCC2; PROPHYLACTIC MEDICATION;

ANIMALS; ANTICONVULSANTS; BRAIN; ELECTROENCEPHALOGRAPHY; EPILEPSY, FRONTAL LOBE; FUROSEMIDE; MALE; RATS; RATS, TRANSGENIC; RECEPTORS, NICOTINIC;

EID: 84886952576     PISSN: 09201211     EISSN: 18726844     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2013.08.018     Document Type: Article

References (39)

1. Ahmad S., Clarke L., Hewett A.J., Richens A. Controlled trial of frusemide as an antiepileptic drug in focal epilepsy. Br. J. Clin. Pharmacol. 1976, 3:621-625.
2. Ben Ari Y., Crepel V., Represa A. Seizures beget seizures in temporal lobe epilepsies: the boomerang effects of newly formed aberrant kainatergic synapses. Epilepsy Curr. 2008, 8:68-72.
3. Berg A.T., Shinnar S. Do seizures beget seizures? An assessment of the clinical evidence in humans. J. Clin. Neurophysiol. 1997, 14:102-110.
4. Berninger B., Poo M.-M. Fast actions of neurotrophic factors. Curr. Opin. Neurobiol. 1996, 6:324-330.
5. Binder D.K., Croll S.D., Gall C.M., Scharfman H.E. BDNF and epilepsy: too much of a good thing?. Trends Neurosci. 2001, 24:47-53.
6. Blumenfeld H. Cellular and network mechanisms of spike-wave seizures. Epilepsia 2005, 46:21-33.
7. Blumenfeld H., Klein J.P., Schridde U., Vestal M., Rice T., Khera D.S., Bashyal C., Giblin K., Paul-Laughinghouse C., Wang F., Phadke A., Mission J., Agarwal R.K., Englot D.J., Motelow J., Nersesyan H., Waxman S.G., Levin A.R. Early treatment suppresses the development of spike-wave epilepsy in a rat model. Epilepsia 2008, 49:400-409.
8. Bonhoeffer T. Neurotrophins and activity-dependent development of the neocortex. Curr. Opin. Neurobiol. 1996, 6:119-126.
9. Cohen I., Navarro V., Clemenceau S., Baulac M., Miles R. On the origin of interictal activity in human temporal lobe epilepsy in vitro. Science 2002, 298:1418-1421.
10. Crompton D.E., Berkovic S.F. The borderland of epilepsy: clinical and molecular features of phenomena that mimic epileptic seizures. Lancet Neurol. 2009, 8:370-381.
11. Esclapez M., Hirsch J.C., Ben Ari Y., Bernard C. Newly formed excitatory pathways provide a substrate for hyperexcitability in experimental temporal lobe epilepsy. J. Comp. Neurol. 1999, 408:449-460.
12. Haglund M.M., Hochman D.W. Furosemide and mannitol suppression of epileptic activity in the human brain. J. Neurophysiol. 2005, 94:907-918.
13. Hauser W.A. Incidence and prevalence. Epilepsy: A Comprehensive Textbook 1997, Philadelphia, Lippincott-Raven. J. Engel, T.A. Pedley (Eds.).
14. Heinemann U. Basic mechanisms of partial epilepsies. Curr. Opin. Neurol. 2004, 17:155-159.
15. Hesdorffer D.C., Stables J.P., Hauser W.A., Annegers J.F., Cascino G. Are certain diuretics also anticonvulsants?. Ann. Neurol. 2001, 50:458-462.
16. Hirose S., Iwata H., Akiyoshi H., Kobayashi K., Ito M., Wada K., Kaneko S., Mitsudome A. A novel mutation of CHRNA4 responsible for autosomal dominant nocturnal frontal lobe epilepsy. Neurology 1999, 53:1749-1753.
17. Hochman D.W. The extracellular space and epileptic activity in the adult brain: explaining the antiepileptic effects of furosemide and bumetanide. Epilepsia 2012, 53:18-25.
18. Hochman D.W., Baraban S.C., Owens J.W., Schwartzkroin P.A. Dissociation of synchronization and excitability in furosemide blockade of epileptiform activity. Science 1995, 270:99-102.
19. Hochman D.W., Schwartzkroin P.A. Chloride-cotransport blockade desynchronizes neuronal discharge in the epileptic hippocampal slice. J. Neurophysiol. 2000, 83:406-417.
20. Holtkamp M., Matzen J., Buchheim K., Walker M.C., Meierkord H. Furosemide terminates limbic status epilepticus in freely moving rats. Epilepsia 2003, 44:1141-1144.
21. Huberfeld G., Wittner L., Clemenceau S., Baulac M., Kaila K., Miles R., Rivera C. Perturbed chloride homeostasis and GABAergic signaling in human temporal lobe epilepsy. J. Neurosci. 2007, 27:9866-9873.
22. Ito M., Kobayashi K., Fujii T., Okuno T., Hirose S., Iwata H., Mitsudome A., Kaneko S. Electroclinical picture of autosomal dominant nocturnal frontal lobe epilepsy in a Japanese family. Epilepsia 2000, 41:52-58.
23. Katz L.C., Shatz C.J. Synaptic activity and the construction of cortical circuits. Science 1996, 274:1133-1138.
24. Kwan P., Brodie M.J. Early identification of refractory epilepsy. N. Engl. J. Med. 2000, 342:314-319.
25. Loscher W., Puskarjov M., Kaila K. Cation-chloride cotransporters NKCC1 and KCC2 as potential targets for novel antiepileptic and antiepileptogenic treatments. Neuropharmacology 2012, 10.1016/j.neuropharm.2012.05.045.
26. Lu B., Figurov A. Role of neurotrophins in synapse development and plasticity. Rev. Neurosci. 1997, 8:1-12.
27. McAllister A.K., Katz L.C., Lo D.C. Neurotrophins and synaptic plasticity. Annu. Rev. Neurosci. 1999, 22:295-318.
28. McCormick D.A., Contreras D. On the cellular and network bases of epileptic seizures. Annu. Rev. Physiol. 2001, 63:815-846.
29. Munoz A., Mendez P., DeFelipe J., Alvarez-Leefmans F.J. Cation-chloride cotransporters and GABA-ergic innervation in the human epileptic hippocampus. Epilepsia 2007, 48:663-673.
30. Najm I.M., Janigro D., Babb T.L. Mechanisms of epileptogenesis and experimental models of seizures. The Treatment of Epilepsy: Principles and Practice 2006, 33-44. Lea & Febiger, Philadelphia. E. Wyllie (Ed.).
31. Phillips H.A., Marini C., Scheffer I.E., Sutherland G.R., Mulley J.C., Berkovic S.F. A de novo mutation in sporadic nocturnal frontal lobe epilepsy. Ann. Neurol. 2000, 48:264-267.
32. Reid K.H., Guo S.Z., Iyer V.G. Agents which block potassium-chloride cotransport prevent sound-triggered seizures in post-ischemic audiogenic seizure-prone rats. Brain Res. 2000, 864:134-137.
33. Reid A.Y., Riazi K., Campbell-Teskey G., Pittman Q.J. Increased excitability and molecular changes in adult rats after a febrile seizure. Epilepsia 2013, 10.1111/epi.12061.
34. - extrusion. J. Cell Biol. 2002, 159:747-752.
35. Rivera C., Voipio J., Thomas-Crusells J., Li H., Emri Z., Sipila S., Payne J.A., Minichiello L., Saarma M., Kaila K. Mechanism of activity-dependent downregulation of the neuron-specific K-Cl cotransporter KCC2. J. Neurosci. 2004, 24:4683-4691.
36. Thoenen H. Neurotrophins and neuronal plasticity. Science 1995, 270:593-598.
37. Traynelis S.F., Dingledine R. Modification of potassium-induced interictal bursts and electrographic seizures by divalent cations. Neurosci. Lett. 1989, 98:194-199.
38. Yoshida S., Saruwatari J., Chen L., Liu F., Iwasa H., Sugawara T., Kaneko S. The Epilepsy Genetic Study Group Japan Individualized medicine for epilepsy-based on genetic information. Epilepsy Seizure 2010, 3:163-191.
39. Zhu G., Okada M., Yoshida S., Ueno S., Mori F., Takahara T., Saito R., Miura Y., Kishi A., Tomiyama M., Sato A., Kojima T., Fukuma G., Wakabayashi K., Hase K., Ohno H., Kijima H., Takano Y., Mitsudome A., Kaneko S., Hirose S. Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype. J. Neurosci. 2008, 28:12465-12476.