The familial hemiplegic migraine type 1 mutation K1336E affects direct G protein-mediated regulation of neuronal P/Q-type Ca2+ channels

Cephalalgia

Volumn 33, Issue 6, 2013, Pages 398-407

  Garza López, Edgar ^a   González Ramírez, Ricardo ^b   Gandini, María A ^a   Sandoval, Alejandro ^c   Felix, Ricardo ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b HOSPITAL GENERAL DR MANUEL GEA GONZÁLEZ   (Mexico)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Ca2+ channels; channelopathies; familial hemiplegic migraine; G protein regulation; P Q type channel

Indexed keywords

CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; CALCIUM ION; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MU OPIATE RECEPTOR; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL CAV2.1 ALPHA1; CACNA1A PROTEIN, HUMAN; CALCIUM CHANNEL; CALCIUM CHANNEL N TYPE; VOLTAGE DEPENDENT CALCIUM CHANNEL (P Q TYPE); VOLTAGE-DEPENDENT CALCIUM CHANNEL (P-Q TYPE);

ARTICLE; CALCIUM CURRENT; COMPLEX FORMATION; CONTROLLED STUDY; FACILITATION; FAMILIAL HEMIPLEGIC MIGRAINE; FAMILIAL HEMIPLEGIC MIGRAINE TYPE I; GAIN OF FUNCTION MUTATION; GENETIC ASSOCIATION; HEK293 CELL LINE; HETEROLOGOUS EXPRESSION; HUMAN; HUMAN CELL; METABOLIC REGULATION; MISSENSE MUTATION; MOLECULAR PATHOLOGY; NERVE CELL EXCITABILITY; NERVE CELL NETWORK; PATCH CLAMP TECHNIQUE; PATHOPHYSIOLOGY; PREPULSE INHIBITION; PRESYNAPTIC INHIBITION; WILD TYPE; CELL STRAIN HEK293; CEREBELLAR ATAXIA; GENETIC TRANSFECTION; GENETICS; METABOLISM; MIGRAINE; NERVE CELL; PATCH CLAMP;

CALCIUM CHANNELS; CALCIUM CHANNELS, N-TYPE; CEREBELLAR ATAXIA; GTP-BINDING PROTEINS; HEK293 CELLS; HUMANS; MIGRAINE DISORDERS; MUTATION, MISSENSE; NEURONS; PATCH-CLAMP TECHNIQUES; TRANSFECTION;

EID: 84886931489     PISSN: 03331024     EISSN: 14682982     Source Type: Journal    
DOI: 10.1177/0333102412475236     Document Type: Article

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