Familial hemiplegic migraine type 1 mutations K1336E, W1684R, and V1696I alter Cav2.1 Ca2+ channel gating: Evidence for β-subunit isoform-specific effects

Journal of Biological Chemistry

Volumn 279, Issue 50, 2004, Pages 51844-51850

  Müllner, Carmen ^a   Broos, Ludo A M ^b   Van Den Maagdenberg, Arn M J M ^c   Striessnig, Jörg ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Department of Human Genetics ^*  (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; ELECTRODES; NEUROLOGY; PATHOLOGY;

CHANNEL ACTIVITY; CHANNEL GATING; HUMAN DISEASES;

CALCIUM;

BARIUM; PROTEIN SUBUNIT; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; FAMILIAL DISEASE; FAMILIAL HEMIPLEGIC MIGRAINE TYPE 1; GENE MUTATION; HEMIPLEGIA; MEMBRANE CURRENT; MIGRAINE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; VOLTAGE CLAMP;

ANIMALS; CALCIUM CHANNELS, N-TYPE; FEMALE; HEMIPLEGIA; HUMANS; ION CHANNEL GATING; MIGRAINE WITH AURA; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; OOCYTES; POINT MUTATION; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; XENOPUS LAEVIS;

ANIMALIA; MAMMALIA;

EID: 10644295470     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M408756200     Document Type: Article

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