Multipoint binding of the SLP-76 SH2 domain to ADAP is critical for oligomerization of SLP-76 signaling complexes in stimulated T cells

Molecular and Cellular Biology

Volumn 33, Issue 21, 2013, Pages 4140-4151

  Coussens, Nathan P ^a,c   Hayashi, Ryo ^a,d   Brown, Patrick H ^b   Balagopalan, Lakshmi ^a   Balbo, Andrea ^b   Akpan, Itoro ^a   Houtman, Jon C D ^a,e   Barr, Valarie A ^a   Schuck, Peter ^a   Appella, Ettore ^a   Samelson, Lawrence E ^a  

^a NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d SAGA UNIVERSITY   (Japan)

^e UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CELL PROTEIN ADAP; MEMBRANE PROTEIN; MEMBRANE PROTEIN SLP76; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CALCIUM SIGNALING; CELL ADHESION; COMPLEX FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HUMAN; HUMAN CELL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; CALCIUM SIGNALING; CELL ADHESION; HUMANS; JURKAT CELLS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PHOSPHOPEPTIDES; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SINGLE-CELL ANALYSIS; SRC HOMOLOGY DOMAINS; T-LYMPHOCYTES; THERMODYNAMICS; TIME-LAPSE IMAGING;

EID: 84886910386     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00410-13     Document Type: Article

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