Marked synergistic bactericidal effects and mode of action of medium-chain fatty acids in combination with organic acids against Escherichia coli O157: H7

Applied and Environmental Microbiology

Volumn 79, Issue 21, 2013, Pages 6552-6560

  Kim, S A ^a   Rhee, M S ^a  

^a Korea University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-MICROBIAL EFFECTS; ANTIMICROBIAL COMPOUNDS; BACTERICIDAL EFFECTS; ESCHERICHIA COLI O157; ESCHERICHIA COLI O157:H7; MEDIUM-CHAIN FATTY ACIDS; MICROSCOPIC ANALYSIS; NATURAL-ANTIMICROBIALS;

BACTERIA; BACTERICIDES; CELL DEATH; CHAINS; CITRIC ACID; FLOW CYTOMETRY; SATURATED FATTY ACIDS; TRANSMISSION ELECTRON MICROSCOPY;

ESCHERICHIA COLI;

COST-BENEFIT ANALYSIS; FATTY ACID; FLOW CYTOMETRY; FOOD INDUSTRY; HEALTH CARE; MEDICINE; MEMBRANE; MICROBIAL COMMUNITY; MICROSCOPY; ORGANIC ACID; SYNERGISM;

ANTIINFECTIVE AGENT; CARBOXYLIC ACID; FATTY ACID;

ARTICLE; CELL DEATH; CELL MEMBRANE; DRUG EFFECT; DRUG POTENTIATION; ESCHERICHIA COLI O157; EVALUATION STUDY; FLOW CYTOMETRY; METABOLISM; PH; TRANSMISSION ELECTRON MICROSCOPY;

ANTI-BACTERIAL AGENTS; CARBOXYLIC ACIDS; CELL DEATH; CELL MEMBRANE; DRUG SYNERGISM; ESCHERICHIA COLI O157; FATTY ACIDS; FLOW CYTOMETRY; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ELECTRON, TRANSMISSION;

EID: 84886899769     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.02164-13     Document Type: Article

References (29)

1. Armstrong GL, Hollingsworth J, Morris JG, Jr. 1996. Emerging foodborne pathogens: Escherichia coli O157:H7 as a model of entry of a new pathogen into the food supply of the developed world. Epidemiol. Rev. 18:29-51.
2. Faith N, Shere J, Brosch R, Arnold K, Ansay S, Lee M, Luchansky J, Kaspar C. 1996. Prevalence and clonal nature of Escherichia coli O157:H7 on dairy farms in Wisconsin. Appl. Environ. Microbiol. 62:1519-1525.
3. Lee GY, Jang HI, Hwang IG, Rhee MS. 2009. Prevalence and classification of pathogenic Escherichia coli isolated from fresh beef, poultry, and pork in Korea. Int. J. Food Microbiol. 134:196-200.
4. Rangel JM, Sparling PH, Crowe C, Griffin PM, Swerdlow DL. 2005. Epidemiology of Escherichia coli O157:H7 outbreaks, United States, 1982-2002. Emerg. Infect. Dis. 11:603-609.
5. Dundas S, Todd WTA, Stewart AI, Murdoch PS, Chaudhuri A, Hutchinson SJ. 2001. The central Scotland Escherichia coli O157:H7 outbreak: risk factors for the hemolytic uremic syndrome and death among hospitalized patients. Clin. Infect. Dis. 33:923-931.
6. Kaper JB, Nataro JP, Mobley HLT. 2004. Pathogenic Escherichia coli. Nat. Rev. Microbiol. 2:123-140.
7. Doyle MP, Schoeni JL. 1987. Isolation of Escherichia coli O157:H7 from retail fresh meats and poultry. Appl. Environ. Microbiol. 53:2394-2396.
8. Mead PS, Griffin PM. 1998. Escherichia coli O157:H7. Lancet 352:1207-1212.
9. Rhee MS, Lee SY, Dougherty RH, Kang DH. 2003. Antimicrobial effects of mustard flour and acetic acid against Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella enterica serovar Typhimurium. Appl. Environ. Microbiol. 69:2959-2963.
10. Tsuboi I, Ida H, Yoshikawa E, Hiyoshi S, Yamaji E, Nakayama I, Nonomiya T, Shigenobu F, Shimizu M, O'Hara K, Sawai T, Mizuoka K. 1998. Antibiotic susceptibility of enterohemorrhagic Escherichia coli O157:H7 isolated from an outbreak in Japan in 1996. Antimicrob. Agents Chemother. 42:431-432.
11. Frenzen PD, Drake A, Angulo FJ. 2005. Economic cost of illness due to Escherichia coli O157 infections in the United States. J. Food Prot. 68: 2623-2630.
12. Bae YY, Lee HJ, Kim SA, Rhee MS. 2009. Inactivation of Alicyclobacillus acidoterrestris spores in apple juice by supercritical carbon dioxide. Int. J. Food Microbiol. 136:95-100.
13. Kim SA, Kim OY, Rhee MS. 2010. Direct application of supercritical carbon dioxide for the reduction of Cronobacter spp. (Enterobacter sakazakii) in end products of dehydrated powdered infant formula. J. Dairy Sci. 93:1854-1860.
14. Zentek J, Buchheit-Renko S, Ferrara F, Vahjen W, Van Kessel A, Pieper R. 2011. Nutritional and physiological role of medium-chain triglycerides and medium-chain fatty acids in piglets. Anim. Health Res. Rev. 12:83-93.
15. Jensen RG. 2002. The composition of bovine milk lipids: January 1995 to December 2000. J. Dairy Sci. 85:295-350.
16. Sprong RC, Hulstein MFE, Van der Meer R. 2001. Bactericidal activities of milk lipids. Antimicrob. Agents Chemother. 45:1298-1301.
17. Korea Food and Drug Administration. 2004. Korea food additives code. Korea Food and Drug Administration, Chungbuk, South Korea. http://fa .kfda.go.kr/foodadditivescode.html. Accessed 1 July 2013.
18. Bergsson G, Arnfinnsson J, Steingrímsson ó, Thormar H. 2001. Killing of Gram positive cocci by fatty acids and monoglycerides. APMIS 109: 670-678.
19. Desbois AP, Smith VJ. 2010. Antibacterial free fatty acids: activities, mechanisms of action and biotechnological potential. Appl. Microbiol. Biotechnol. 85:1629-1642.
20. Wang LL, Johnson EA. 1992. Inhibition of Listeria monocytogenes by fatty acids and monoglycerides. Appl. Environ. Microbiol. 58:624-629.
21. Piper P, Calderon CO, Hatzixanthis K, Mollapour M. 2001. Weak acid adaptation: the stress response that confers yeasts with resistance to organic acid food preservatives. Microbiology 147:2635-2642.
22. Brul S, Coote P. 1999. Preservative agents in foods: mode of action and microbial resistance mechanisms. Int. J. Food Microbiol. 50:1-17.
23. Davidson PM, Branen AL. 2005. Food antimicrobials-an introduction, p 1-10. In Davidson PM, Sofos JN, Branen AL (ed), Antimicrobials in food, 3rd ed. CRC Press, Boca Raton, FL.
24. Altieri C, Bevilacqua A, Cardillo D, Sinigaglia M. 2009. Effectiveness of fatty acids and their monoglycerides against gram negative pathogens. Int. J. Food Sci. Technol. 44:359-366.
25. Doores S. 2005. Organic acids, p 91-141. In Davidson PM, Sofos JN, Branen AL (ed), Antimicrobials in food, 3rd ed. CRC Press, Boca Raton, FL.
26. Hsiao CP, Siebert KJ. 1999. Modeling the inhibitory effects of organic acids on bacteria. Int. J. Food Microbiol. 47:189-201.
27. U.S. Food and Drug Administration. 2013. Database of Select Committee on GRAS Substances. U.S. Food and Drug Administration, Rockville, MD. http://www.accessdata.fda.gov/scripts/fcn/fcnNavigation .cfm?rpt=scogsListing. Accessed 1 July 2013.
28. Nair M, Joy J, Vasudevan P, Hinckley L, Hoagland T, Venkitanarayanan K. 2005. Antibacterial effect of caprylic acid and monocaprylin on major bacterial mastitis pathogens. J. Dairy Sci. 88:3488-3495.
29. Nobmann P, Smith A, Dunne J, Henehan G, Bourke P. 2009. The antimicrobial efficacy and structure activity relationship of novel carbohydrate fatty acid derivatives against Listeria spp. and food spoilage microorganisms. Int. J. Food Microbiol. 128:440-445.