Validation of an analytical LC-MS/MS method in human plasma for the pharmacokinetic study of atomoxetine

Journal of Analytical Chemistry

Volumn 68, Issue 11, 2013, Pages 986-991

  Choi, C I ^a   Jang, C G ^a   Bae, J W ^a,b   Lee, S Y ^a  

^a Sungkyunkwan University   (South Korea)

^b Daegu University   (South Korea)

Author keywords

atomoxetine; human plasma; LC ESI MS MS; pharmacokinetics

Indexed keywords

ATOMOXETINE; COEFFICIENTS OF VARIATIONS; HUMAN PLASMAS; LC-ESI-MS/MS; LIQUID-LIQUID EXTRACTION; LOWER LIMIT OF QUANTIFICATIONS; MULTIPLE-REACTION MONITORING MODES; PHARMACOKINETIC PARAMETERS;

CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS;

PLASMA (HUMAN);

EID: 84886874692     PISSN: 10619348     EISSN: None     Source Type: Journal    
DOI: 10.1134/S1061934813110051     Document Type: Article

References (17)

1. Wong, D.T.; Threlkeld, P.G.; Best, K.L.; and Bymaster, F.P.; J. Pharmacol. Exp. Ther.; 1982, vol. 222, no. 1, p. 61.
2. Gehlert, D.R.; Gackenheimer, S.L.; and Robertson, D.W.; Neurosci. Lett.; 1993, vol. 157, no. 2, p. 203.
3. Bymaster, F.P.; Katner, J.S.; Nelson, D.L.; Hemrick-Luecke, S.K.; Threlkeld, P.G.; Heiligenstein, J.H.; Morin, S.M.; Gehlert, D.R.; and Perry, K.W.; Neuropsychopharmacology, 2002, vol. 27, no. 5, p. 699.
4. Sauer, J.M.; Ring, B.J.; and Witcher, J.W.; Clin. Pharmacokinet.; 2005, vol. 44, no. 6, p. 571.
5. Sauer, J.M.; Ponsler, G.D.; Mattiuz, E.L.; Long, A.J.; Witcher, J.W.; Thomasson, H.R.; and Desante, K.A.; Drug Metab. Dispos.; 2003, vol. 31, no. 1, p. 98.
6. Belle, D.J.; Ernest, C.S.; Sauer, J.M.; Smith, B.P.; Thomasson, H.R.; and Witcher, J.W.; J. Clin. Pharmacol.; 2002, vol. 42, no. 11, p. 1219.
7. Chalon, S.A.; Desager, J.P.; Desante, K.A.; Frye, R.F.; Witcher, J.; Long, A.J.; Sauer, J.M.; Golnez, J.L.; Smith, B.P.; Thomasson, H.R.; and Horsmans, Y.; Clin. Pharmacol. Ther.; 2003, vol. 73, no. 3, p. 178.
8. Sauer, J.M.; Long, A.J.; Ring, B.; Gillespie, J.S.; Sanburn, N.P.; DeSante, K.A.; Petullo, D.; VandenBranden, M.R.; Jensen, C.B.; Wrighton, S.A.; Smith, B.P.; Read, H.A.; and Witcher, J.W.; J. Pharmacol. Exp. Ther.; 2004, vol. 308, no. 2, p. 410.
9. Witcher, J.W.; Long, A.; Smith, B.; Sauer, J.M.; Heilgenstein, J.; Wilens, T.; Spencer, T.; and Biederman, J.; J. Child. Adolesc. Psychopharmacol.; 2003, vol. 13, no. 1, p. 53.
10. Cui, Y.M.; Teng, C.H.; Pan, A.X.; Yuen, E.; Yeo, K.P.; Zhou, Y.; Zhao, X.; Long, A.J.; Bangs, M.E.; and Wise, S.D.; Br. J. Clin. Pharmacol.; 2007, vol. 64, no. 4, p. 445.
11. Zhu, H.J.; Wang, J.S.; Donovan, J.L.; DeVane, C.L.; Gibson, B.B.; and Markowitz, J.S.; J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.; 2007, vol. 846, nos. 1-2, p. 351.
12. Patel, C.; Patel, M.; Rani, S.; Nivsarkar, M.; and Padh, H.; J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.; 2007, vol. 850, no. 1-2, p. 356.
13. Guo, W.; Li, W.; Guo, G.; Zhang, J.; Zhou, B.; Zhai, Y.; and Wang, C.; J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.; 2007, vol. 854, nos. 1-2, p. 128.
14. Mattiuz, E.L.; Ponsler, G.D.; Barbuch, R.J.; Wood, P.G.; Mullen, J.H.; Shugert, R.L.; Li, Q.; Wheeler, W.J.; Kuo, F.; Conrad, P.C.; and Sauer, J.M.; Drug Metab. Dispos.; 2003, vol. 31, no. 1, p. 88.
15. Mullen, J.H.; Shugert, R.L.; Ponsler, G.D.; Li Q.; Sundaram, B.; Coales, H.L.; Yakupkovic, J.E.; Lelacheur, R.M.; Wheeler, W.J.; Belas, F.J.; and Sauer, J.M.; J. Pharm. Biomed. Anal.; 2005, vol. 38, no. 4, p. 720.
16. Rybak, M.E.; Parker, D.L.; and Pfeiffer, C.M.; J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.; 2008, vol. 861, no. 1, p. 145.
17. Ring, B.J.; Gillespie, J.S.; Eckstein, J.A.; and Wrighton, S.A.; Drug Metab. Dispos.; 2002, vol. 30, no. 3, p. 319.