CK2 in Embryonic Development

Protein Kinase CK2

Volumn , Issue , 2013, Pages 129-168

  Alvarez, Laura Macias ^a   Revuelta Cervantes, Jesus ^a   Dominguez, Isabel ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Developmental signaling pathways; Function; Invertebrate development; Plant development; Vertebrate development; Yeast biology

Indexed keywords

EID: 84886806300     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781118482490.ch4     Document Type: Chapter

References (189)

1. Ahmad KA, Wang G, Unger G, Slaton J, Ahmed K. 2008. Protein kinase CK2-a key sup- pressor of apoptosis. Adv Enzyme Regul 48:179-187.
2. Akten B, Jauch E, Genova GK, Kim EY, Edery I, Raabe T, Jackson FR. 2003. A role for CK2 in the Drosophila circadian oscillator. Nat Neurosci 6:251-257.
3. Al-Khouri AM, Ma Y, Togo SH, Williams S, Mustelin T. 2005. Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta. J Biol Chem 280:35195-35202.
4. Allada R, Meissner RA. 2005. Casein kinase 2, circadian clocks, and the flight from muta- genic light. Mol Cell Biochem 274:141-149.
5. Alvarado-Diaz CP, Tapia JC, Antonelli M, Moreno, RD. 2009. Differential localization of alpha' and beta subunits of protein kinase CK2 during rat spermatogenesis. Cell Tissue Res 338:139-149.
6. Andersson ER, Sandberg R, Lendahl, U. 2011. Notch signaling: simplicity in design, versatil- ity in function. Development 138:3593-3612.
7. Antonelli M, Daniotti JL, Rojo D, Allende CC, Allende JE. 1996. Cloning, expression and properties of the alpha' subunit of casein kinase 2 from zebrafish (Danio rerio). Eur J Biochem 241:272-279.
8. Arrigoni G, Pagano MA, Sarno S, Cesaro L, James P, Pinna LA. 2008. Mass spectrometry analysis of a protein kinase CK2beta subunit interactome isolated from mouse brain by affinity chromatography. J Proteome Res 7:990-1000.
9. Bai X, Chan ED, Xu X. 2003. The protein of a new gene, Tctex4, interacts with protein kinase CK2beta subunit and is highly expressed in mouse testis. Biochem Biophys Res Commun 307:86-91.
10. Bai X, Silvius D, Chan ED, Escalier D, Xu, SX. 2009. Identification and characterization of a novel testis-specific gene CKT2, which encodes a substrate for protein kinase CK2. Nucleic Acids Res 37:2699-2711.
11. Barker N, Clevers H. 2006. Mining the Wnt pathway for cancer therapeutics. Nat Rev Drug Discov 5:997-1014.
12. Bettencourt-Dias M, Giet R, Sinka R, Mazumdar A, Lock WG, Balloux F, Zafiropoulos PJ, Yamaguchi S, Winter S, Carthew RW, Cooper M, Jones D, Frenz L, Glover, DM. 2004. Genome-wide survey of protein kinases required for cell cycle progression. Nature 432:980-987.
13. Bibby AC, Litchfield DW. 2005. The Multiple Personalities of the Regulatory Subunit of Protein Kinase CK2: CK2 Dependent and CK2 Independent Roles Reveal a Secret Identity for CK2beta. Int J Biol Sci 1:67-79.
14. Bidwai AP, Reed JC, Glover CV. 1994. Casein kinase II of Saccharomyces cerevisiae contains two distinct regulatory subunits, beta and beta'. Arch Biochem Biophys 309:348-355.
15. Bidwai AP, Reed JC, Glover, CV. 1995. Cloning and disruption of CKB1, the gene encoding the 38-kDa beta subunit of Saccharomyces cerevisiae casein kinase II (CKII). Deletion of CKII regulatory subunits elicits a salt-sensitive phenotype. J Biol Chem 270:10395-10404.
16. Bidwai AP, Zhao W, Glover, CV. 1999. A gene located at 56F1-2 in Drosophila melanogaster encodes a novel metazoan beta-like subunit of casein kinase II. Mol Cell Biol Res Commun 1:21-28.
17. Blanquet PR. 2000. Casein kinase 2 as a potentially important enzyme in the nervous system. Prog Neurobiol 60:211-246.
18. Blond O, Jensen HH, Buchou T, Cochet C, Issinger OG, Boldyreff B. 2005. Knocking out the regulatory beta subunit of protein kinase CK2 in mice: gene dosage effects in ES cells and embryos. Mol Cell Biochem 274:31-37.
19. Boldyreff B, Issinger OG. 1997. A-Raf kinase is a new interacting partner of protein kinase CK2 beta subunit. FEBS Lett 403:197-199.
20. Boldyreff B, Wehr K, Hecht R, Issinger, OG. 1992. Identification of four genomic loci highly related to casein-kinase-2-alpha cDNA and characterization of a casein kinase-2-alpha pseudogene within the mouse genome. Biochem Biophys Res Commun 186:723-730.
21. Bonnet H, Filhol O, Truchet I, Brethenou P, Cochet C, Amalric F, Bouche G. 1996. Fibroblast growth factor-2 binds to the regulatory beta subunit of CK2 and directly stimulates CK2 activity toward nucleolin. J Biol Chem 271:24781-24787.
22. Bose A, Kahali B, Zhang S, Lin JM, Allada R, Karandikar U, Bidwai, AP. 2006. Drosophila CK2 regulates lateral-inhibition during eye and bristle development. Mech Dev 123: 649-664.
23. Boskey AL, Stiner D, Doty SB, Binderman I, Leboy P. 1992. Studies of mineralization in tissue culture: optimal conditions for cartilage calcification. Bone Miner 16:11-36.
24. Bourbon HM, Martin-Blanco E, Rosen D, Kornberg TB. 1995. Phosphorylation of the Dro- sophila engrailed protein at a site outside its homeodomain enhances DNA binding. J Biol Chem 270:11130-11139.
25. Bragdon B, Thinakaran S, Moseychuk O, Gurski L, Bonor J, Price C, Wang L, Beamer WG, Nohe A. 2011. Casein kinase 2 regulates in vivo bone formation through its interaction with bone morphogenetic protein receptor type Ia. Bone 49:944-954.
26. Bragdon B, Thinakaran S, Moseychuk O, King D, Young K, Litchfield DW, Petersen NO, Nohe A. 2010. Casein kinase 2 beta-subunit is a regulator of bone morphogenetic protein 2 signaling. Biophys J 99:897-904.
27. Bren GD, Pennington KN, Paya CV. 2000. PKC-zeta-associated CK2 participates in the turnover of free IkappaBalpha. J Mol Biol 297:1245-1258.
28. Bryja V, Schambony A, Cajanek L, Dominguez I, Arenas E, Schulte G. 2008. Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways. EMBO Rep 9:1244-1250.
29. Buchou T, Vernet M, Blond O, Jensen HH, Pointu H, Olsen BB, Cochet C, Issinger OG, Boldyreff, B. 2003. Disruption of the regulatory beta subunit of protein kinase CK2 in mice leads to a cell-autonomous defect and early embryonic lethality. Mol Cell Biol 23:908-915.
30. Canton DA, Litchfield DW. 2006. The shape of things to come: an emerging role for protein kinase CK2 in the regulation of cell morphology and the cytoskeleton. Cell Signal 18:267-275.
31. Carneiro AC, Fragel-Madeira L, Silva-Neto MA, Linden R. 2008. A role for CK2 upon interkinetic nuclear migration in the cell cycle of retinal progenitor cells. Dev Neurobiol 68:620-631.
32. Castelli M, Camps M, Gillieron C, Leroy D, Arkinstall S, Rommel C, Nichols A. 2004. MAP Kinase Phosphatase 3 (MKP3) Interacts with and Is Phosphorylated by Protein Kinase CK2a. Journal of Biological Chemistry 279:44731-44739.
33. Cavin LG, Romieu-Mourez R, Panta GR, Sun J, Factor VM, Thorgeirsson SS, Sonenshein GE, Arsura M. 2003. Inhibition of CK2 activity by TGF-beta1 promotes IkappaB-alpha protein stabilization and apoptosis of immortalized hepatocytes. Hepatology 38:1540-1551.
34. Chaverneff F, Barrett J. 2009. Casein kinase II contributes to the synergistic effects of BMP7 and BDNF on Smad 1/5/8 phosphorylation in septal neurons under hypoglycemic stress. J Neurochem 109:733-743.
35. Chen X, Yang J, Evans PM, Liu C. 2008. Wnt signaling: the good and the bad. Acta Biochim Biophys Sin (Shanghai) 40:577-594.
36. Chen-Wu JL, Padmanabha R, Glover CV. 1988. Isolation, sequencing, and disruption of the CKA1 gene encoding the alpha subunit of yeast casein kinase II. Mol Cell Biol 8:4981-4990.
37. Cheusova T, Khan MA, Schubert SW, Gavin AC, Buchou T, Jacob G, Sticht H, Allende J, Boldyreff B, Brenner HR, Hashemolhosseini S. 2006. Casein kinase 2-dependent serine phosphorylation of MuSK regulates acetylcholine receptor aggregation at the neuromus- cular junction. Genes Dev 20:1800-1816.
38. Chien AJ, Conrad WH, Moon RT. 2009. A Wnt survival guide: from flies to human disease. J Invest Dermatol 129:1614-1627.
39. Clevers H. 2006. Wnt/beta-catenin signaling in development and disease. Cell 127:469-480.
40. Crawford AD, Liekens S, Kamuhabwa AR, Maes J, Munck S, Busson R, Rozenski J, Esguerra CV, de Witte PA. 2011. Zebrafish bioassay-guided natural product discovery: isolation of angiogenesis inhibitors from East African medicinal plants. PLoS ONE 6:e14694.
41. Daniotti JL, Allende ML, Weinberg ES, Allende JE. 1994. Cloning and expression of genes coding for protein kinase CK2 alpha and beta subunits in zebrafish (Danio rerio). Cell Mol Biol Res 40:431-439.
42. Delalande C, Belle R, Cormier P, Mulner-Lorillon O. 1999. Transient increase of a protein kinase activity identified to CK2 during sea urchin development. Biochem Biophys Res Commun 266:425-431.
43. Deshiere A, Duchemin-Pelletier E, Spreux E, Ciais D, Forcet C, Cochet C, Filhol O. 2011. Regulation of epithelial to mesenchymal transition: CK2ß on stage. Molecular and Cel- lular Biochemistry 356:11-20.
44. Di Maira G, Salvi M, Arrigoni G, Marin O, Sarno S, Brustolon F, Pinna LA, Ruzzene M. 2005. Protein kinase CK2 phosphorylates and upregulates Akt/PKB. Cell Death Differ 12:668-677.
45. Diaz-Nido J, Serrano L, Mendez E, Avila J. 1988. A casein kinase II-related activity is involved in phosphorylation of microtubule-associated protein MAP-1B during neuroblas- toma cell differentiation. J Cell Biol 106:2057-2065.
46. Dobrowolska G, Meggio F, Szczegielniak J, Muszynska G, Pinna LA. 1992. Purification and characterization of maize seedling casein kinase IIB, a monomeric enzyme immunolo- gically related to the alpha subunit of animal casein kinase-2. Eur J Biochem 204: 299-303.
47. Dominguez I, Degano IR, Chea K, Cha J, Toselli P, Seldin DC. 2011. CK2alpha is essential for embryonic morphogenesis. Mol Cell Biochem 356:209-216.
48. Dominguez I, Mizuno J, Wu H, Imbrie GA, Symes K, Seldin DC. 2005. A role for CK2alpha/ beta in Xenopus early embryonic development. Mol Cell Biochem 274:125-131.
49. Dominguez I, Mizuno J, Wu H, Song DH, Symes K, Seldin DC. 2004. Protein kinase CK2 is required for dorsal axis formation in Xenopus embryos. Dev Biol 274:110-124.
50. Dominguez I, Sonenshein GE, Seldin DC. 2009. Protein kinase CK2 in health and disease: CK2 and its role in Wnt and NF-kappaB signaling: linking development and cancer. Cell Mol Life Sci 66:1850-1857.
51. Dorey K, Amaya E. 2010. FGF signalling: diverse roles during early vertebrate embryogen- esis. Development 137:3731-3742.
52. Eastwood K, Yin C, Bandyopadhyay M, Bidwai A. 2011. New insights into the Orange domain of E(spl)-M8, and the roles of the C-terminal domain in autoinhibition and Groucho recruitment. Mol Cell Biochem 356:217-225.
53. Escalier D, Silvius D, Xu X. 2003. Spermatogenesis of mice lacking CK2alpha': failure of germ cell survival and characteristic modifications of the spermatid nucleus. Mol Reprod Dev 66:190-201.
54. Faust M, Montenarh M. 2000. Subcellular localization of protein kinase CK2. A key to its function? Cell Tissue Res 301:329-340.
55. Faust RA, Tawfic S, Davis AT, Bubash LA, Ahmed K. 2000. Antisense oligonucleotides against protein kinase CK2-alpha inhibit growth of squamous cell carcinoma of the head and neck in vitro. Head Neck 22:341-346.
56. Fialho E, Masuda H, Silva-Neto MA. 1999. Protein phosphorylation during Rhodnius pro- lixus embryogenesis: protein kinase casein kinase II activity. Insect Biochem Mol Biol 29:215-223.
57. Filhol O, Nueda A, Martel V, Gerber-Scokaert D, Benitez MJ, Souchier C, Saoudi Y, Cochet C. 2003. Live-cell fluorescence imaging reveals the dynamics of protein kinase CK2 individual subunits. Mol Cell Biol 23:975-987.
58. Finkielsztein A, Kelly GM. 2009. Altering PI3K-Akt signalling in zebrafish embryos affects PTEN phosphorylation and gastrulation. Biol Cell 101:661-678, 4 p following 678.
59. Fraser AG, Kamath RS, Zipperlen P, Martinez-Campos M, Sohrmann M, Ahringer J. 2000. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature 408:325-330.
60. Gao Y, Wang HY. 2006. Casein kinase 2 Is activated and essential for Wnt/beta-catenin sig- naling. J Biol Chem 281:18394-18400.
61. Ghosh-Dastidar S, Narayanan S, Stifani S, D'Mello SR. 2012. Transducin-like Enhancer of split-1 (TLE1) combines with Forkhead box protein G1 (FoxG1) to promote neuronal survival. J Biol Chem.
62. Glover CV, 3rd. 1998. On the physiological role of casein kinase II in Saccharomyces cere- visiae. Prog Nucleic Acid Res Mol Biol 59:95-133.
63. Glover CV, Shelton ER, Brutlag, DL. 1983. Purification and characterization of a type II casein kinase from Drosophila melanogaster. J Biol Chem 258:3258-3265.
64. Grigoryan T, Wend P, Klaus A, Birchmeier W. 2008. Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev 22:2308-2341.
65. Guerra B, Issinger OG. 1999. Protein kinase CK2 and its role in cellular proliferation, devel- opment and pathology. Electrophoresis 20:391-408.
66. Guerra B, Siemer S, Boldyreff B, Issinger OG. 1999. Protein kinase CK2: evidence for a protein kinase CK2beta subunit fraction, devoid of the catalytic CK2alpha subunit, in mouse brain and testicles. FEBS Lett 462:353-357.
67. Hagemann C, Kalmes A, Wixler V, Wixler L, Schuster T, Rapp UR. 1997. The regulatory subunit of protein kinase CK2 is a specific A-Raf activator. FEBS Lett 403:200-202.
68. Hamblet NS, Lijam N, Ruiz-Lozano P, Wang J, Yang Y, Luo Z, Mei L, Chien KR, Sussman DJ, Wynshaw-Boris A. 2002. Dishevelled 2 is essential for cardiac outflow tract develop- ment, somite segmentation and neural tube closure. Development 129:5827-5838.
69. Hammerlein A, Weiske J, Huber O. 2005. A second protein kinase CK1-mediated step nega- tively regulates Wnt signalling by disrupting the lymphocyte enhancer factor-1/beta- catenin complex. Cell Mol Life Sci 62:606-618.
70. Hanna DE, Rethinaswamy A, Glover CV. 1995. Casein kinase II is required for cell cycle progression during G1 and G2/M in Saccharomyces cerevisiae. J Biol Chem 270:25905-25914.
71. Hauck L, Harms C, An J, Rohne J, Gertz K, Dietz R, Endres M, von Harsdorf R. 2008. Protein kinase CK2 links extracellular growth factor signaling with the control of p27(Kip1) stability in the heart. Nat Med 14:315-324.
72. Heiker JT, Wottawah CM, Juhl C, Kosel D, Morl K, Beck-Sickinger AG. 2009. Protein kinase CK2 interacts with adiponectin receptor 1 and participates in adiponectin signaling. Cell Signal 21:936-942.
73. Hilgard P, Huang T, Wolkoff AW, Stockert RJ. 2002. Translated Alu sequence determines nuclear localization of a novel catalytic subunit of casein kinase 2. Am J Physiol Cell Physiol 283:C472-C483.
74. Homma MK, Li D, Krebs EG, Yuasa Y, Homma Y. 2002. Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein. Proc Natl Acad Sci USA 99:5959-5964.
75. Hu E, Rubin CS. 1990. Casein kinase II from Caenorhabditis elegans. Properties and devel- opmental regulation of the enzyme; cloning and sequence analyses of cDNA and the gene for the catalytic subunit. J Biol Chem 265:5072-5080.
76. Hu E, Rubin CS. 1991. Casein kinase II from Caenorhabditis elegans. Cloning, characteriza- tion, and developmental regulation of the gene encoding the beta subunit. J Biol Chem 266:19796-19802.
77. Hu J, Bae YK, Knobel KM, Barr MM. 2006. Casein kinase II and calcineurin modulate TRPP function and ciliary localization. Mol Biol Cell 17:2200-2211.
78. Huillard E, Ziercher L, Blond O, Wong M, Deloulme JC, Souchelnytskyi S, Baudier J, Cochet C, Buchou T. 2010. Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol 30: 2737-2749.
79. Imbrie GA, Wu H, Seldin DC, Dominguez I. 2012. Assymetric localization of CK2alpha during Xenopus oogenesis. Human Genet Embryol S4:001.
80. Ingham PW, Nakano Y, Seger, C. 2011. Mechanisms and functions of Hedgehog signalling across the metazoa. Nat Rev Genet 12:393-406.
81. Isaeva AR, Mitev VI. 2011. The protein kinase CK2 inhibitor TBB mediates up-regulation of MEK3/6 and p38 activities, down-regulation of ERK1/2 activity and induction of G1/S arrest in normal human epidermal autocrine proliferating keratinocytes. Journal of Der- matological Science 63:124-126.
82. Jaffe L, Ryoo HD, Mann RS. 1997. A role for phosphorylation by casein kinase II in modu- lating Antennapedia activity in Drosophila. Genes Dev 11:1327-1340.
83. Janeczko M, Maslyk M, Szyszka R, Baier A. 2011. Interactions between subunits of protein kinase CK2 and their protein substrates influences its sensitivity to specific inhibitors. Mol Cell Biochem 356:121-126.
84. Jauch E, Melzig J, Brkulj M, Raabe T. 2002. In vivo functional analysis of Drosophila protein kinase casein kinase 2 (CK2) beta-subunit. Gene 298:29-39.
85. Jauch E, Wecklein H, Stark F, Jauch M, Raabe T. 2006. The Drosophila melanogaster DmCK- 2beta transcription unit encodes for functionally non-redundant protein isoforms. Gene 374:142-152.
86. Jedlicki A, Hinrichs MV, Allende CC, Allende JE. 1992. The cDNAs coding for the alpha- and beta-subunits of Xenopus laevis casein kinase II. FEBS Lett 297:280-284.
87. Ji H, Wang J, Nika H, Hawke D, Keezer S, Ge Q, Fang B, Fang X, Fang D, Litchfield DW, Aldape K, Lu Z. 2009. EGF-induced ERK activation promotes CK2-mediated disassocia- tion of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin. Mol Cell 36:547-559.
88. Jia H, Liu Y, Xia R, Tong C, Yue T, Jiang J, Jia J. 2010. Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus. J Biol Chem 285:37218-37226.
89. Juhl C, Mörl K, Beck-Sickinger A. 2011. Adiponectin receptor 1 interacts with both subunits of protein kinase CK2. Molecular and Cellular Biochemistry 356:185-189.
90. Kahali B, Trott R, Paroush Z, Allada R, Bishop CP, Bidwai AP. 2008. Drosophila CK2 phos- phorylates Hairy and regulates its activity in vivo. Biochem Biophys Res Commun 373:637-642.
91. Kalmykova AI, Shevelyov YY, Polesskaya OO, Dobritsa AA, Evstafieva AG, Boldyreff B, Issinger OG, Gvozdev VA. 2002. CK2(beta)tes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster. Eur J Biochem 269:1418-1427.
92. Karandikar U, Anderson S, Mason N, Trott RL, Bishop CP, Bidwai AP. 2003. The Drosophila SSL gene is expressed in larvae, pupae, and adults, exhibits sexual dimorphism, and mimics properties of the beta subunit of casein kinase II. Biochem Biophys Res Commun 301:941-947.
93. Karandikar UC, Trott RL, Yin J, Bishop CP, Bidwai AP. 2004. Drosophila CK2 regulates eye morphogenesis via phosphorylation of E(spl)M8. Mech Dev 121:273-286.
94. Karki S, Tokito MK, Holzbaur EL. 1997. Casein kinase II binds to and phosphorylates cyto- plasmic dynein. J Biol Chem 272:5887-5891.
95. Kawamoto M, Fujiwara A, Kuno S, Yasumasu I. 2000. Changes in the activities of protein phosphatase type 1 and type 2A in sea urchin embryos during early development. Zygote 8 Suppl 1:S68-S69.
96. Kietzmann A, Wang Y, Weber D, Steinbeisser H. 2012. Xenopus paraxial protocadherin inhibits Wnt/beta-catenin signalling via casein kinase 2beta. EMBO Rep 13:129-134.
97. Kim ST, Marquard K, Stephens S, Louden E, Allsworth J, Moley KH. 2011. Adiponectin and adiponectin receptors in the mouse preimplantation embryo and uterus. Human Reproduc- tion 26:82-95.
98. Kopan R, Ilagan MXG. 2009. The Canonical Notch Signaling Pathway: Unfolding the Activa- tion Mechanism. Cell 137:216-233.
99. Kopatz I, Naiman T, Eli D, Canaani D. 1990. The nucleotide sequence of the mouse cDNA encoding the beta subunit of casein kinase II. Nucleic Acids Res 18:3639.
100. Kramerov AA, Saghizadeh M, Caballero S, Shaw LC, Li Calzi S, Bretner M, Montenarh M, Pinna LA, Grant MB, Ljubimov AV. 2008. Inhibition of protein kinase CK2 suppresses angiogenesis and hematopoietic stem cell recruitment to retinal neovascularization sites. Mol Cell Biochem 316:177-186.
101. Krek W, Maridor G, Nigg EA. 1992. Casein kinase II is a predominantly nuclear enzyme. J Cell Biol 116:43-55.
102. Kuntamalla PP, Kunttas-Tatli E, Karandikar U, Bishop CP, Bidwai AP. 2008. Drosophila protein kinase CK2 is rendered temperature-sensitive by mutations of highly conserved residues flanking the activation segment. Mol Cell Biochem.
103. Kuntamalla PP, Kunttas-Tatli E, Karandikar U, Bishop CP, Bidwai AP. 2009. Drosophila protein kinase CK2 is rendered temperature-sensitive by mutations of highly conserved residues flanking the activation segment. Mol Cell Biochem 323:49-60.
104. Landesman-Bollag E, Belkina A, Hovey B, Connors E, Cox C, Seldin DC. 2011. Develop- mental and growth defects in mice with combined deficiency of CK2 catalytic genes. Mol Cell Biochem 356:227-231.
105. Lee J, Richburg JH, Shipp EB, Meistrich ML, Boekelheide K. 1999. The Fas system, a regula- tor of testicular germ cell apoptosis, is differentially up-regulated in Sertoli cell versus germ cell injury of the testis. Endocrinology 140:852-858.
106. Lee NY, Haney JC, Sogani J, Blobe GC. 2009. Casein kinase 2beta as a novel enhancer of activin-like receptor-1 signaling. Faseb J 23:3712-3721.
107. Lemeer S, Pinkse MW, Mohammed S, van Breukelen B, den Hertog J, Slijper M, Heck AJ. 2008. Online automated in vivo zebrafish phosphoproteomics: from large-scale analysis down to a single embryo. J Proteome Res 7:1555-1564.
108. Li D, Dobrowolska G, Krebs EG. 1996. The Physical Association of Casein Kinase 2 with Nucleolin. Journal of Biological Chemistry 271:15662-15668.
109. Lin JM, Kilman VL, Keegan K, Paddock B, Emery-Le M, Rosbash M, Allada R. 2002. A role for casein kinase 2alpha in the Drosophila circadian clock. Nature 420:816-820.
110. Litchfield DW. 2003. Protein kinase CK2: structure, regulation and role in cellular decisions of life and death. Biochem J 369:1-15.
111. Liu ZP, Galindo RL, Wasserman SA. 1997. A role for CKII phosphorylation of the cactus PEST domain in dorsoventral patterning of the Drosophila embryo. Genes Dev 11:3413-3422.
112. Logan CY, Nusse R. 2004. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 20:781-810.
113. Lorenz P, Pepperkok R, Ansorge W, Pyerin W. 1993. Cell biological studies with monoclonal and polyclonal antibodies against human casein kinase II subunit beta demonstrate par- ticipation of the kinase in mitogenic signaling. J Biol Chem 268:2733-2739.
114. Lou DY, Dominguez I, Toselli P, Landesman-Bollag E, O'Brien C, Seldin DC. 2008. The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic develop- ment. Mol Cell Biol 28:131-139.
115. Luo J, Chen J, Deng ZL, Luo X, Song WX, Sharff KA, Tang N, Haydon RC, Luu HH, He TC. 2007. Wnt signaling and human diseases: what are the therapeutic implications? Lab Invest 87:97-103.
116. Luscher B, Litchfield DW. 1994. Biosynthesis of casein kinase II in lymphoid cell lines. Eur J Biochem 220:521-526.
117. MacDonald BT, Tamai K, He X. 2009. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17:9-26.
118. Maizel A, Tassetto M, Filhol O, Cochet C, Prochiantz A, Joliot A. 2002. Engrailed homeo- protein secretion is a regulated process. Development 129:3545-3553.
119. Mannowetz N, Kartarius S, Wennemuth G, Montenarh M. 2010. Protein kinase CK2 and new binding partners during spermatogenesis. Cell Mol Life Sci 67:3905-3913.
120. Maridor G, Park W, Krek W, Nigg EA. 1991. Casein kinase II. cDNA sequences, develop- mental expression, and tissue distribution of mRNAs for alpha, alpha', and beta subunits of the chicken enzyme. J Biol Chem 266:2362-2368.
121. Mason I. 1994. Cell signalling. Do adhesion molecules signal via FGF receptors? Curr Biol 4:1158-1161.
122. Meggio F, Pinna LA. 2003. One-thousand-and-one substrates of protein kinase CK2? Faseb J 17:349-368.
123. Mestres P, Boldyreff B, Ebensperger C, Hameister H, Issinger OG. 1994. Expression of casein kinase 2 during mouse embryogenesis. Acta Anat (Basel) 149:13-20.
124. Miravet S, Piedra J, Miro F, Itarte E, Garcia de Herreros A, Dunach M. 2002. The transcrip- tional factor Tcf-4 contains different binding sites for beta-catenin and plakoglobin. J Biol Chem 277:1884-1891.
125. Moon RT, Kohn AD, De Ferrari GV, Kaykas A. 2004. WNT and beta-catenin signalling: diseases and therapies. Nat Rev Genet 5:691-701.
126. Moreno-Romero J, Espunya MC, Platara M, Arino J, Martinez MC. 2008. A role for protein kinase CK2 in plant development: evidence obtained using a dominant-negative mutant. Plant J 55:118-130.
127. Mulekar JJ, Bu Q, Chen F, Huq E. 2012. Casein kinase II alpha subunits affect multiple developmental and stress-responsive pathways in Arabidopsis. Plant J 69:343-354.
128. Murtaza I, Wang HX, Feng X, Alenina N, Bader M, Prabhakar BS, Li PF. 2008. Down- regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hyper- trophy. J Biol Chem 28:35996-36004.
129. Nishio S-I, Gibert Y, Bernard L, Brunet F, Triqueneaux G, Laudet V. 2008. Adiponectin and adiponectin receptor genes are coexpressed during zebrafish embryogenesis and regulated by food deprivation. Developmental Dynamics 237:1682-1690.
130. Nuthall HN, Husain J, McLarren KW, Stifani S. 2002. Role for Hes1-induced phosphorylation in Groucho-mediated transcriptional repression. Mol Cell Biol 22:389-399.
131. Orlandini M, Semplici F, Ferruzzi R, Meggio F, Pinna LA, Oliviero S. 1998. Protein kinase CK2alpha' is induced by serum as a delayed early gene and cooperates with Ha-ras in fibroblast transformation. J Biol Chem 273:21291-21297.
132. Packman LC, Kubota K, Parker J, Gay NJ. 1997. Casein kinase II phosphorylates Ser468 in the PEST domain of the Drosophila IkappaB homologue cactus. FEBS Lett 400:45-50.
133. Padmanabha R, Chen-Wu JL, Hanna DE, Glover CV. 1990. Isolation, sequencing, and disrup- tion of the yeast CKA2 gene: casein kinase II is essential for viability in Saccharomyces cerevisiae. Mol Cell Biol 10:4089-4099.
134. Penner CG, Wang Z, Litchfield DW. 1997. Expression and localization of epitope-tagged protein kinase CK2. J Cell Biochem 64:525-537.
135. Pepperkok R, Lorenz P, Jakobi R, Ansorge W, Pyerin W. 1991. Cell growth stimulation by EGF: inhibition through antisense-oligodeoxynucleotides demonstrates important role of casein kinase II. Exp Cell Res 197:245-253.
136. Peracchia G, Jensen AB, Culianez-Macia FA, Grosset J, Goday A, Issinger OG, Pages M. 1999. Characterization, subcellular localization and nuclear targeting of casein kinase 2 from Zea mays. Plant Mol Biol 40:199-211.
137. Pirrello O, Machev N, Schimdt F, Terriou P, Menezo Y, Viville S. 2005. Search for mutations involved in human globozoospermia. Hum Reprod 20:1314-1318.
138. Popovici C, Berda Y, Conchonaud F, Harbis A, Birnbaum D, Roubin R. 2006. Direct and heterologous approaches to identify the LET-756/FGF interactome. BMC Genomics 7:105.
139. Pukrop T, Gradl D, Henningfeld KA, Knochel W, Wedlich D, Kuhl M. 2001. Identification of two regulatory elements within the high mobility group box transcription factor XTCF.J Biol Chem 276:8968-8978.
140. Ranganathan P, Vasquez-Del Carpio R, Kaplan FM, Wang H, Gupta A, Van Wye JD, Capobianco AJ. 2011. Hierarchical phosphorylation within the ankyrin repeat domain defines a phosphoregulatory loop that regulates Notch transcriptional activity. J Biol Chem 286:28844-28857.
141. Rasmussen T, Skjoth IH, Jensen HH, Niefind K, Boldyreff B, Issinger OG. 2005. Biochemical characterization of the recombinant human Drosophila homologues Timekeeper and Andante involved in the Drosophila circadian oscillator. Mol Cell Biochem 274:151-161.
142. Reed JC, Bidwai AP, Glover CV. 1994. Cloning and disruption of CKB2, the gene encoding the 32-kDa regulatory beta'-subunit of Saccharomyces cerevisiae casein kinase II. J Biol Chem 269:18192-18200.
143. Rethinaswamy A, Birnbaum MJ, Glover CV. 1998. Temperature-sensitive mutations of the CKA1 gene reveal a role for casein kinase II in maintenance of cell polarity in Saccha- romyces cerevisiae. J Biol Chem 273:5869-5877.
144. Riera M, Figueras M, Lopez C, Goday A, Pages M. 2004. Protein kinase CK2 modulates developmental functions of the abscisic acid responsive protein Rab17 from maize. Proc Natl Acad Sci USA 101:9879-9884.
145. Riera M, Peracchia G, de Nadal E, Arino J, Pages M. 2001. Maize protein kinase CK2: regu- lation and functionality of three beta regulatory subunits. Plant J 25:365-374.
146. Roussou I, Draetta G. 1994. The Schizosaccharomyces pombe casein kinase II alpha and beta subunits: evolutionary conservation and positive role of the beta subunit. Mol Cell Biol 14:576-586.
147. Russo GL, Tosto M, Mupo A, Castellano I, Cuomo A, Tosti E. 2004. Biochemical and func- tional characterization of protein kinase CK2 in ascidian Ciona intestinalis oocytes at fertilization. Cloning and sequence analysis of cDNA for alpha and beta subunits. J Biol Chem 279:33012-33023.
148. Sawada H, Yamahama Y, Yamamoto T, Togawa T, Mase K. 2012. Developmental changes in the localization of protein kinase CK2 in non-diapause and diapause eggs of the silkworm. Bombyx mori. Zoolog Sci 29:6-10.
149. Schmidt-Spaniol I, Grimm B, Issinger OG. 1993. Subcellular localization of protein kinase CK-2 alpha- and beta-subunits in synchronized cells from primary human fibroblasts and established cell lines. Cell Mol Biol Res 39:761-772.
150. Schneider HR, Reichert GH, Issinger OG. 1986. Enhanced casein kinase II activity during mouse embryogenesis. Identification of a 110-kDa phosphoprotein as the major phos- phorylation product in mouse embryos and Krebs II mouse ascites tumor cells. Eur J Biochem 161:733-738.
151. Seeber S, Issinger OG, Holm T, Kristensen LP, Guerra B. 2005. Validation of protein kinase CK2 as oncological target. Apoptosis 10:875-885.
152. Seldin DC, Landesman-Bollag E, Farago M, Currier N, Lou D, Dominguez I. 2005. CK2 as a positive regulator of Wnt signalling and tumourigenesis. Mol Cell Biochem 274:63-67.
153. Seldin DC, Lou DY, Toselli P, Landesman-Bollag E, Dominguez I. 2008. Gene targeting of CK2 catalytic subunits. Mol Cell Biochem 316:141-147.
154. Semplici F, Meggio F, Pinna LA, Oliviero S. 2002. CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with beta-TrCP and enhances beta-catenin degradation. Oncogene 21:3978-3987.
155. Serrano L, Diaz-Nido J, Wandosell F, Avila J. 1987. Tubulin phosphorylation by casein kinase II is similar to that found in vivo. J Cell Biol 105:1731-1739.
156. Silva-Neto MA, Fialho E, Paes MC, Oliveira PL, Masuda H. 2002. Cyclic nucleotide- independent phosphorylation of vitellin by casein kinase II purified from Rhodnius pro- lixus oocytes. Insect Biochem Mol Biol 32:847-857.
157. Singh NN, Ramji DP. 2006. Transforming growth factor-beta-induced expression of the apolipoprotein E gene requires c-Jun N-terminal kinase, p38 kinase, and casein kinase 2. Arterioscler Thromb Vasc Biol 26:1323-1329.
158. Skjerpen CS, Nilsen T, Wesche J, Olsnes S. 2002. Binding of FGF-1 variants to protein kinase CK2 correlates with mitogenicity. EMBO J 21:4058-4069.
159. Snell V, Nurse P. 1994. Genetic analysis of cell morphogenesis in fission yeast-a role for casein kinase II in the establishment of polarized growth. Embo J 13:2066-2074.
160. Sommercorn J, Krebs EG. 1987. Induction of casein kinase II during differentiation of 3T3-L1 cells. J Biol Chem 262:3839-3843.
161. Song DH, Dominguez I, Mizuno J, Kaut M, Mohr SC, Seldin DC. 2003. CK2 phosphoryla- tion of the armadillo repeat region of beta-catenin potentiates Wnt signaling. J Biol Chem 278:24018-24025.
162. Song DH, Sussman DJ, Seldin DC. 2000. Endogenous protein kinase CK2 participates in Wnt Signaling in mammary epithelial cells. J Biol Chem 275:23790-23797.
163. Tan WQ, Wang JX, Lin ZQ, Li YR, Lin Y, Li PF. 2008. Novel cardiac apoptotic pathway: the dephosphorylation of apoptosis repressor with caspase recruitment domain by calcineurin. Circulation 118:2268-2276.
164. Tapia JC, Torres VA, Rodriguez DA, Leyton L, Quest AF. 2006. Casein kinase 2 (CK2) increases survivin expression via enhanced beta-catenin-T cell factor/lymphoid enhancer binding factor-dependent transcription. Proc Natl Acad Sci USA 103:15079-15084.
165. Toczyski DP, Galgoczy DJ, Hartwell LH. 1997. CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Cell 90:1097-1106.
166. Trott RL, Kalive M, Paroush Z, Bidwai AP. 2001. Drosophila melanogaster casein kinase II interacts with and phosphorylates the basic helix-loop-helix proteins m5, m7, and m8 derived from the Enhancer of split complex. J Biol Chem 276:2159-2167.
167. Varjosalo M, Taipale J. 2008. Hedgehog: functions and mechanisms. Genes Dev 22: 2454-2472.
168. Velez-Bermudez IC, Irar S, Carretero-Paulet L, Pages M, Riera M. 2011. Specific character- istics of CK2beta regulatory subunits in plants. Mol Cell Biochem 356:255-260.
169. Wang H, Davis A, Yu S, Ahmed K. 2001. Response of cancer cells to molecular interruption of the CK2 signal. Mol Cell Biochem 227:167-174.
170. Wang S, Jones KA. 2006. CK2 controls the recruitment of Wnt regulators to target genes in vivo. Curr Biol 16:2239-2244.
171. Waxman JS, Hocking AM, Stoick CL, Moon RT. 2004. Zebrafish Dapper1 and Dapper2 play distinct roles in Wnt-mediated developmental processes. Development 131:5909-5921.
172. Wilhelm N, Kostelnik K, Gotz C, Montenarh M. 2012. Protein kinase CK2 is implicated in early steps of the differentiation of pre-adipocytes into adipocytes. Mol Cell Biochem.
173. Wilhelm V, Neckelman G, Allende JE, Allende CC. 2001. The genomic structure of two protein kinase CK2alpha genes of Xenopus laevis and features of the putative promoter region. Mol Cell Biochem 227:175-183.
174. Wilhelm V, Rojas P, Gatica M, Allende CC, Allende JE. 1995. Expression of the subunits of protein kinase CK2 during oogenesis in Xenopus laevis. Eur J Biochem 232:671-676.
175. Willert K, Brink M, Wodarz A, Varmus H, Nusse R. 1997. Casein kinase 2 associates with and phosphorylates dishevelled. Embo J 16:3089-3096.
176. Wirkner U, Voss H, Ansorge W, Pyerin W. 1998. Genomic organization and promoter identi- fication of the human protein kinase CK2 catalytic subunit alpha (CSNK2A1). Genomics 48:71-78.
177. Wong LC, Costa A, McLeod I, Sarkeshik A, Yates J, 3rd, Kyin S, Perlman D, Schedl P. 2011. The functioning of the Drosophila CPEB protein Orb is regulated by phosphorylation and requires casein kinase 2 activity. PLoS ONE 6:e24355.
178. Wu H, Symes K, Seldin DC, Dominguez I. 2009. Threonine 393 of beta-catenin regulates interaction with Axin. J Cell Biochem 108:52-63.
179. Xu X, Rich ES, Jr, Seldin DC. 1998. Murine protein kinase CK2 alpha': cDNA and genomic cloning and chromosomal mapping. Genomics 48:79-86.
180. Xu X, Toselli PA, Russell LD, Seldin DC. 1999. Globozoospermia in mice lacking the casein kinase II alpha' catalytic subunit. Nat Genet 23:118-121.
181. Yamamoto T, Kanekatsu M, Nakagoshi M, Kato T, Mase K, Sawada H. 2005. Casein kinase 2 during early embryonic development in silkworm Bombyx mori: cDNA sequence, gene expression, and enzyme activity. DNA Seq 16:446-455.
182. Yde CW, Olsen BB, Meek D, Watanabe N, Guerra B. 2008. The regulatory beta-subunit of protein kinase CK2 regulates cell-cycle progression at the onset of mitosis. Oncogene 27:4986-4997.
183. Yu IJ, Spector DL, Bae YS, Marshak DR. 1991. Immunocytochemical localization of casein kinase II during interphase and mitosis. J Cell Biol 114:1217-1232.
184. Zhang C, Vilk G, Canton DA, Litchfield DW. 2002. Phosphorylation regulates the stability of the regulatory CK2beta subunit. Oncogene 21:3754-3764.
185. Zhang Y, Qiu WJ, Chan SC, Han J, He X, Lin SC. 2002. Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways. J Biol Chem 7:7.
186. Zheng Y, Qin H, Frank SJ, Deng L, Litchfield DW, Tefferi A, Pardanani A, Lin F-T, Li J, Sha B, Benveniste EN. 2011. A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway. Blood 118:156-166.
187. Zhu D, Hensel J, Hilgraf R, Abbasian M, Pornillos O, Deyanat-Yazdi G, Hua XH, Cox S. 2010. Inhibition of protein kinase CK2 expression and activity blocks tumor cell growth. Mol Cell Biochem 333:159-167.
188. Zien P, Duncan JS, Skierski J, Bretner M, Litchfield DW, Shugar D. 2005. Tetrabromobenzo- triazole (TBBt) and tetrabromobenzimidazole (TBBz) as selective inhibitors of protein kinase CK2: evaluation of their effects on cells and different molecular forms of human CK2. Biochim Biophys Acta 1754:271-280.
189. Ziercher L, Filhol O, Laudet B, Prudent R, Cochet C, Buchou T. 2011. Structure-function analysis of the beta regulatory subunit of protein kinase CK2 by targeting embryonic stem cell. Mol Cell Biochem 356:75-81.